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The map label for this gene is accA

Identifier: 54293768

GI number: 54293768

Start: 932691

End: 933644

Strand: Direct

Name: accA

Synonym: lpl0824

Alternate gene names: 54293768

Gene position: 932691-933644 (Clockwise)

Preceding gene: 54293764

Following gene: 54293769

Centisome position: 27.88

GC content: 43.4

Gene sequence:

>954_bases
ATGACCCGACAATTTTTGGAATTTGAACAACCTATTGAAGAGTTGAATCAAAAAATTGAAGCACTGCGTATGGTTGGCAG
TGATAATGAAGTTAATTTAAGTGAAGAGATAGCTCGACTTGAAGCAAAATGCTCCGAGTTAACAGAGAATATATTCTCCA
GGCTCGAACCATGGCAAATCGCTCAGATGGCTAGACATCCTTTAAGGCCACAGACCACTGACTATATTGAGCGAATTTTT
ACTGATTTTCAGGAGTTGCATGGTGATCGCAGTTATTCTTCAGCCCCTGCAATTATCGGAGGCATGGCGCGATTAAACGG
GGAGCCTGTCATGGTACTTGGTCACCAAAAAGGTAAACGTACCAAGGAAAAAGTATACAGAAACTTTGGTATGGCAAGAC
CTGAAGAATACAGGAAAGCACTGCGTTTGATGAGGATGGCTGAAAAATTCAAAATGCCTGTAGTCACATTTATTGATACG
GCTGGAGCTTATCCTGGCATAGGTGCTGAAGAACGTAACCAATCAGAAGCCATTGCACGGAATCTTTTTGCTATGTCTCG
CATTAAAACACCAATTGTCTGTATTGTTACAGGAGAAGCCGGTTCAGGTGGTGCCTTGGCGATTGGGGTCGGTGATAAGA
TTATTATGCTGCAATTCAGCATTTATTCCGTCATTTCTCCTGAGGGGTGCGCCTCAATCCTTTGGAAAGACGCCTCTAAA
GCGAGTGAAGCTGCGCGTGCTATGGGAATTACTGCAGACAGAATATTCGAAAATGAATTGGTTGATATGGTAGTTCCTGA
GCCTTTGGGGGGCGCACACCGAGACGTTGATGAGATGGCAAGTCGCTTGAAGAGATTATTAACGAGTGAACTCCAGGCTT
TGAAAAAGGTGCCTCTGGATCAATTAATTGAGTTAAGGTATCAAAAGTTTATGGCAATGGGTGCTTGTGACTAG

Upstream 100 bases:

>100_bases
TAAATCCTGTAATTATCATCTGTTGTATCTGAAATCTGGCATCGATTAACGGTTAAGAGTATCATATACCAAAGATGTTT
AATTCACCAAAGAGTAATCA

Downstream 100 bases:

>100_bases
GCCTTTACTAAGTCCCGAATGGGTAGCTCGCCTTAAACAATTCAAGAAATTGATAGTAGGGTTCAGTGGTGGTCTGGACT
CTACAGTGCTCCTGCATGTC

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTRQFLEFEQPIEELNQKIEALRMVGSDNEVNLSEEIARLEAKCSELTENIFSRLEPWQIAQMARHPLRPQTTDYIERIF
TDFQELHGDRSYSSAPAIIGGMARLNGEPVMVLGHQKGKRTKEKVYRNFGMARPEEYRKALRLMRMAEKFKMPVVTFIDT
AGAYPGIGAEERNQSEAIARNLFAMSRIKTPIVCIVTGEAGSGGALAIGVGDKIIMLQFSIYSVISPEGCASILWKDASK
ASEAARAMGITADRIFENELVDMVVPEPLGGAHRDVDEMASRLKRLLTSELQALKKVPLDQLIELRYQKFMAMGACD

Sequences:

>Translated_317_residues
MTRQFLEFEQPIEELNQKIEALRMVGSDNEVNLSEEIARLEAKCSELTENIFSRLEPWQIAQMARHPLRPQTTDYIERIF
TDFQELHGDRSYSSAPAIIGGMARLNGEPVMVLGHQKGKRTKEKVYRNFGMARPEEYRKALRLMRMAEKFKMPVVTFIDT
AGAYPGIGAEERNQSEAIARNLFAMSRIKTPIVCIVTGEAGSGGALAIGVGDKIIMLQFSIYSVISPEGCASILWKDASK
ASEAARAMGITADRIFENELVDMVVPEPLGGAHRDVDEMASRLKRLLTSELQALKKVPLDQLIELRYQKFMAMGACD
>Mature_316_residues
TRQFLEFEQPIEELNQKIEALRMVGSDNEVNLSEEIARLEAKCSELTENIFSRLEPWQIAQMARHPLRPQTTDYIERIFT
DFQELHGDRSYSSAPAIIGGMARLNGEPVMVLGHQKGKRTKEKVYRNFGMARPEEYRKALRLMRMAEKFKMPVVTFIDTA
GAYPGIGAEERNQSEAIARNLFAMSRIKTPIVCIVTGEAGSGGALAIGVGDKIIMLQFSIYSVISPEGCASILWKDASKA
SEAARAMGITADRIFENELVDMVVPEPLGGAHRDVDEMASRLKRLLTSELQALKKVPLDQLIELRYQKFMAMGACD

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=60.5678233438486, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_LEGPA (Q5X6W5)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123178.1
- ProteinModelPortal:   Q5X6W5
- SMR:   Q5X6W5
- STRING:   Q5X6W5
- GeneID:   3116672
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0849
- LegioList:   lpp0849
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   LPNE297246:LPP0849-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35506; Mature: 35374

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQFLEFEQPIEELNQKIEALRMVGSDNEVNLSEEIARLEAKCSELTENIFSRLEPWQI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQMARHPLRPQTTDYIERIFTDFQELHGDRSYSSAPAIIGGMARLNGEPVMVLGHQKGKR
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCH
TKEKVYRNFGMARPEEYRKALRLMRMAEKFKMPVVTFIDTAGAYPGIGAEERNQSEAIAR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
NLFAMSRIKTPIVCIVTGEAGSGGALAIGVGDKIIMLQFSIYSVISPEGCASILWKDASK
HHHHHHHCCCCEEEEEECCCCCCCEEEEECCCEEEEEEHHHHHHCCCCHHHHHHHHHHHH
ASEAARAMGITADRIFENELVDMVVPEPLGGAHRDVDEMASRLKRLLTSELQALKKVPLD
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
QLIELRYQKFMAMGACD
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRQFLEFEQPIEELNQKIEALRMVGSDNEVNLSEEIARLEAKCSELTENIFSRLEPWQI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQMARHPLRPQTTDYIERIFTDFQELHGDRSYSSAPAIIGGMARLNGEPVMVLGHQKGKR
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCH
TKEKVYRNFGMARPEEYRKALRLMRMAEKFKMPVVTFIDTAGAYPGIGAEERNQSEAIAR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
NLFAMSRIKTPIVCIVTGEAGSGGALAIGVGDKIIMLQFSIYSVISPEGCASILWKDASK
HHHHHHHCCCCEEEEEECCCCCCCEEEEECCCEEEEEEHHHHHHCCCCHHHHHHHHHHHH
ASEAARAMGITADRIFENELVDMVVPEPLGGAHRDVDEMASRLKRLLTSELQALKKVPLD
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
QLIELRYQKFMAMGACD
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA