Click here to switch to the map view.

The map label for this gene is cidA1 [H]

Identifier: 54293220

GI number: 54293220

Start: 300160

End: 300549

Strand: Reverse

Name: cidA1 [H]

Synonym: lpl0268

Alternate gene names: 54293220

Gene position: 300549-300160 (Counterclockwise)

Preceding gene: 54293223

Following gene: 54293219

Centisome position: 8.98

GC content: 40.0

Gene sequence:

>390_bases
ATGGCAAACAAAATTCAGCAAAATTCATTTTTTCAGATAATATTGGTTGGCTTATTTTGGTTAGCTAGTGAGTTATTGCT
CAAACTAGTCAAGCTTCCTTTGTCCGGAGGAATCCTTGGATTAGGAATTGTTTTACTGCTTTTGGCGACGAACTGCTTAA
AATTAAATCGTATAAGACGGGGGGCTGAGTTACTCCTTGCCAATATGTTACTTTTTTTTATCCCTGGCGTCCTTGCAATA
CTGGAGCACCAGGAATTTATCGGTCTTTTAGGCCTTAAAATTCTCTTTATTATTCTGCTCAGCACAATCACGGTGATGCT
AGTCACTGCCCTTGTTGTAGATTATTGCTACCGTTGGAGAACGCATCATGCCAAGCAGCATTCTCTCTGA

Upstream 100 bases:

>100_bases
TTCCATATTGGAAAGGTTATTAGTCTATAAATTCATTTTATTCATCTTAATTAAAAGTGTAAACTTAAATGAAAAAATAA
TATCCATCATGAGCATATAT

Downstream 100 bases:

>100_bases
ATCCATGATCCAGGCATTTTTCTGGTCGCTTATCACAATAGGCATGTATTTTATTACCCAAAAACTATATAGAAGATGGC
CTTTTTGGTGGCTAATGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MANKIQQNSFFQIILVGLFWLASELLLKLVKLPLSGGILGLGIVLLLLATNCLKLNRIRRGAELLLANMLLFFIPGVLAI
LEHQEFIGLLGLKILFIILLSTITVMLVTALVVDYCYRWRTHHAKQHSL

Sequences:

>Translated_129_residues
MANKIQQNSFFQIILVGLFWLASELLLKLVKLPLSGGILGLGIVLLLLATNCLKLNRIRRGAELLLANMLLFFIPGVLAI
LEHQEFIGLLGLKILFIILLSTITVMLVTALVVDYCYRWRTHHAKQHSL
>Mature_128_residues
ANKIQQNSFFQIILVGLFWLASELLLKLVKLPLSGGILGLGIVLLLLATNCLKLNRIRRGAELLLANMLLFFIPGVLAIL
EHQEFIGLLGLKILFIILLSTITVMLVTALVVDYCYRWRTHHAKQHSL

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 14504; Mature: 14373

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKIQQNSFFQIILVGLFWLASELLLKLVKLPLSGGILGLGIVLLLLATNCLKLNRIRR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GAELLLANMLLFFIPGVLAILEHQEFIGLLGLKILFIILLSTITVMLVTALVVDYCYRWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THHAKQHSL
HHHHHHCCC
>Mature Secondary Structure 
ANKIQQNSFFQIILVGLFWLASELLLKLVKLPLSGGILGLGIVLLLLATNCLKLNRIRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GAELLLANMLLFFIPGVLAILEHQEFIGLLGLKILFIILLSTITVMLVTALVVDYCYRWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THHAKQHSL
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]