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The map label for this gene is gap [H]

Identifier: 54293100

GI number: 54293100

Start: 168183

End: 169175

Strand: Reverse

Name: gap [H]

Synonym: lpl0138

Alternate gene names: 54293100

Gene position: 169175-168183 (Counterclockwise)

Preceding gene: 54293101

Following gene: 54293099

Centisome position: 5.06

GC content: 45.22

Gene sequence:

>993_bases
ATGACAATACGAGTCGCGATTAATGGCTATGGCCGCATTGGCCGTTGCATTTTAAGATCGATTTTTGAATACAACAGGCA
AAATGAGTTTGAAGTCGTTGCCATTAACGATTTATCTGGCATCGATGTGACCGCTCACCTGACTCGCTACGATTCAACTC
ACGGCCCTTTTCGCTCGGATGTGAGCATAGAAGGAAACATGCTGATTGTTGATGGGCATGGCATTCAAGTGATTGCTGAG
CGCGATCCGGCCAAACTGCCATGGAAACAATTAGACATTGATATCGTCTTTGAATGCACCGGTTTCTTTACCAGCAGAGA
TGCGGCAATGGGTCATATCAATGCCGGCGCCAAAAAAGTATTAATATCTGCCCCGGCCAAAGGCGTTGATACGACAGTGG
TCTATGGAGTTAATCACTCCGTCATCAAAGCGTCTGATGTCATTGTGTCTAACGCTTCCTGTACAACAAACTGCCTGGCG
CCAGTAGTTAAAGTGTTACATGATGCCATAGGAATTGAATCAGGATTGGTCAACACTGTCCATGCTTATACAAAAGATCA
AATGCTTTTGGATGGAAGCCATAAAGATTTACGGCGCGCCCGCTCTGCAACACAGTCCATCATTCCAACCAAAACCGGCG
CTGCCGCAGCCGTTGGATTGGTTTTACCTGAACTGGCAGGGAAATTGGACGGATTTGCGATGCGAGTACCGGTATTAAAC
GTATCCGTTGTTGATTTAACTTTCCAGGCAAAACGCGCAACTTCTGTGGAAGAAGTCAATGACATCTTGCGCAAGGCTAA
AAGCCGAATTTTACAAATTAATGAGGACCCTTTAGTTTCTTGTGACTTCAATCACAACCCCGCTTCCGCTATTTTCGACA
CAACAGAAACCAAAGTGATAGGCAATTTGGTCAAAGTAGTAGCCTGGTATGACAATGAATGGGGTTTCTCTAACCGCATG
ATTGATACCGCACACCAAATGATGAATTGCTAA

Upstream 100 bases:

>100_bases
CAAACAAACAATGGTGTAACCCATACCCCTTCTGAAGTTTCAAGAAGGCCTGTATTCAGTCTGACTGAGTATGGAGGTTA
CCCTAACTCGGAGAAGTAGT

Downstream 100 bases:

>100_bases
AGGATAACCAATGAACCTGATTAAAATGAGCGACATTGATCTGTCTGGCAAAAGAGTCCTGATTCGTGAGGATTTAAATG
TCCCGATCAAAGACGGCATG

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSDVSIEGNMLIVDGHGIQVIAE
RDPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVIVSNASCTTNCLA
PVVKVLHDAIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGKLDGFAMRVPVLN
VSVVDLTFQAKRATSVEEVNDILRKAKSRILQINEDPLVSCDFNHNPASAIFDTTETKVIGNLVKVVAWYDNEWGFSNRM
IDTAHQMMNC

Sequences:

>Translated_330_residues
MTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSDVSIEGNMLIVDGHGIQVIAE
RDPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVIVSNASCTTNCLA
PVVKVLHDAIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGKLDGFAMRVPVLN
VSVVDLTFQAKRATSVEEVNDILRKAKSRILQINEDPLVSCDFNHNPASAIFDTTETKVIGNLVKVVAWYDNEWGFSNRM
IDTAHQMMNC
>Mature_329_residues
TIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSDVSIEGNMLIVDGHGIQVIAER
DPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVIVSNASCTTNCLAP
VVKVLHDAIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGKLDGFAMRVPVLNV
SVVDLTFQAKRATSVEEVNDILRKAKSRILQINEDPLVSCDFNHNPASAIFDTTETKVIGNLVKVVAWYDNEWGFSNRMI
DTAHQMMNC

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=43.6746987951807, Blast_Score=269, Evalue=3e-72,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=42.6865671641791, Blast_Score=251, Evalue=5e-67,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=48.948948948949, Blast_Score=327, Evalue=8e-91,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=48.4756097560976, Blast_Score=300, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=48.3383685800604, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=48.3383685800604, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=47.4320241691843, Blast_Score=267, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=47.4320241691843, Blast_Score=267, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=327, Percent_Identity=49.2354740061162, Blast_Score=298, Evalue=8e-82,
Organism=Saccharomyces cerevisiae, GI6322409, Length=327, Percent_Identity=47.4006116207951, Blast_Score=293, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6321631, Length=327, Percent_Identity=48.3180428134557, Blast_Score=289, Evalue=4e-79,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=44.9230769230769, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=43.8438438438438, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=43.8438438438438, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=43.5435435435435, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=43.5435435435435, Blast_Score=255, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35949; Mature: 35817

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSD
CEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCC
VSIEGNMLIVDGHGIQVIAERDPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKV
CEECCCEEEEECCCEEEEECCCCCCCCHHHCCEEEEEEEECCEECCCCCCEECCCCCEEE
LISAPAKGVDTTVVYGVNHSVIKASDVIVSNASCTTNCLAPVVKVLHDAIGIESGLVNTV
EEECCCCCCCCEEEEECCCCEEEECEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
HAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGKLDGFAMRVPVLN
HHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEE
VSVVDLTFQAKRATSVEEVNDILRKAKSRILQINEDPLVSCDFNHNPASAIFDTTETKVI
EEEEEEEEECHHCCCHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCHHEECCHHHHHH
GNLVKVVAWYDNEWGFSNRMIDTAHQMMNC
HHHHEEEEEECCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSD
EEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCC
VSIEGNMLIVDGHGIQVIAERDPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKV
CEECCCEEEEECCCEEEEECCCCCCCCHHHCCEEEEEEEECCEECCCCCCEECCCCCEEE
LISAPAKGVDTTVVYGVNHSVIKASDVIVSNASCTTNCLAPVVKVLHDAIGIESGLVNTV
EEECCCCCCCCEEEEECCCCEEEECEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
HAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGKLDGFAMRVPVLN
HHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEE
VSVVDLTFQAKRATSVEEVNDILRKAKSRILQINEDPLVSCDFNHNPASAIFDTTETKVI
EEEEEEEEECHHCCCHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCHHEECCHHHHHH
GNLVKVVAWYDNEWGFSNRMIDTAHQMMNC
HHHHEEEEEECCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7763137 [H]