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The map label for this gene is mdtN [H]

Identifier: 54292979

GI number: 54292979

Start: 19163

End: 20236

Strand: Direct

Name: mdtN [H]

Synonym: lpl0015

Alternate gene names: 54292979

Gene position: 19163-20236 (Clockwise)

Preceding gene: 54292978

Following gene: 54292980

Centisome position: 0.57

GC content: 36.13

Gene sequence:

>1074_bases
GTGAAAGAGAAGTTTGCCACATGGTATAAAATAGTAACTAAACATATCCGGTTTTTCTTTAGTTATTCTATCCCTATGTT
TTTTAAAAAGGCTAAAAATTACATCAATCTTCCCATTATTGTCGTTGGCTTGGCTCTTATTATTGGCCTTTTTCATTTAT
TTTCCTATTTGCTCCCTTTCACTGACAATGCGTTTGTTGTTACTAATGTTACCCCTGTAGCTGCTGATGTATCTGGTTTT
ATTACAGAAATCTATGTAAAGAATGGCCAAAAAGTAAAGAAGAACGATCCTATATTTAGCGTTTACAGGATTCCTTATGA
GTTGGCTTATCAACAAGCAATGGCTGATTACAAGGAAGGATTAAAAAAAATAGACGTATTTCAAAAGCAGATTGAAAGAA
CGGTTGCTTTGATTAAAGCAACGGACGCTGAGCTTGAAAAAGCTCAATTTGCTCTTGGCCTTAAAAAAAATAAGAATGTG
GCCGAAGCAGTATCTGTTCTTGAATTAAAAAATCTTGGTTATGATGTTTCTACTTTAAGTAATAAAAGAAATGCCCTGCA
ACAGGAAGTGGCGGTTTTGCAAGCCAAGATTGAACAACAAAGACATACTGTCGCCAGCCTTAAGGCAAAAATGGATAATG
CCAAGGTTAATCTTGATTTAACCATTGTCAGAGCCCCTGGTGATGGAGTGATAGATAATATGTATGTCTCTCCAAATACC
CCTATCGAGATCCATAAACCGGTGTTTTCTTTTATAGATACGGCAAACTATTATATCCAGGCTAATTTTAATGAAACAGA
CTTACGCAATGTACGTCAAGGTGATAAAGCGTATATCATTTTACGCATGTATTATTTTGACAAAATATTTCATGGGGTTG
TTGTCAACTCGTTATGGGCTGCTGAACGACAAAGCACTGCTCCAAAGAGTCAAATTCAGGTTGTTACAAATCAAAATGAA
TGGCTGTTGCTTCCTCAGCGATTTCCATTACAAATCAAGATATTGGATCCCGATCCTGACTACCCTTTAAATCCTGGCGC
CAGTGCTTATGTTTATATCTCAACTAAAAGATAA

Upstream 100 bases:

>100_bases
TTTTAATGCCGAAAAAGGGAGAGCCTTGTCATGGGGTTTCTCTCTTTGAGAGATAAACTGATGTTGTATTATAGAGTCAT
CATCAAAGAGGCGCTGCATT

Downstream 100 bases:

>100_bases
GCTCGCATCCTACGATAGGTATAAAGAAAATCGTATTAATGGACTAAAAGCAGTATTTGTTTTGGAACTGATGATTATAT
TTTATTTTTTTTCTTCCATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKEKFATWYKIVTKHIRFFFSYSIPMFFKKAKNYINLPIIVVGLALIIGLFHLFSYLLPFTDNAFVVTNVTPVAADVSGF
ITEIYVKNGQKVKKNDPIFSVYRIPYELAYQQAMADYKEGLKKIDVFQKQIERTVALIKATDAELEKAQFALGLKKNKNV
AEAVSVLELKNLGYDVSTLSNKRNALQQEVAVLQAKIEQQRHTVASLKAKMDNAKVNLDLTIVRAPGDGVIDNMYVSPNT
PIEIHKPVFSFIDTANYYIQANFNETDLRNVRQGDKAYIILRMYYFDKIFHGVVVNSLWAAERQSTAPKSQIQVVTNQNE
WLLLPQRFPLQIKILDPDPDYPLNPGASAYVYISTKR

Sequences:

>Translated_357_residues
MKEKFATWYKIVTKHIRFFFSYSIPMFFKKAKNYINLPIIVVGLALIIGLFHLFSYLLPFTDNAFVVTNVTPVAADVSGF
ITEIYVKNGQKVKKNDPIFSVYRIPYELAYQQAMADYKEGLKKIDVFQKQIERTVALIKATDAELEKAQFALGLKKNKNV
AEAVSVLELKNLGYDVSTLSNKRNALQQEVAVLQAKIEQQRHTVASLKAKMDNAKVNLDLTIVRAPGDGVIDNMYVSPNT
PIEIHKPVFSFIDTANYYIQANFNETDLRNVRQGDKAYIILRMYYFDKIFHGVVVNSLWAAERQSTAPKSQIQVVTNQNE
WLLLPQRFPLQIKILDPDPDYPLNPGASAYVYISTKR
>Mature_357_residues
MKEKFATWYKIVTKHIRFFFSYSIPMFFKKAKNYINLPIIVVGLALIIGLFHLFSYLLPFTDNAFVVTNVTPVAADVSGF
ITEIYVKNGQKVKKNDPIFSVYRIPYELAYQQAMADYKEGLKKIDVFQKQIERTVALIKATDAELEKAQFALGLKKNKNV
AEAVSVLELKNLGYDVSTLSNKRNALQQEVAVLQAKIEQQRHTVASLKAKMDNAKVNLDLTIVRAPGDGVIDNMYVSPNT
PIEIHKPVFSFIDTANYYIQANFNETDLRNVRQGDKAYIILRMYYFDKIFHGVVVNSLWAAERQSTAPKSQIQVVTNQNE
WLLLPQRFPLQIKILDPDPDYPLNPGASAYVYISTKR

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=312, Percent_Identity=28.525641025641, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789637, Length=327, Percent_Identity=26.9113149847095, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790024, Length=268, Percent_Identity=25.7462686567164, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790012, Length=292, Percent_Identity=27.0547945205479, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081951, Length=324, Percent_Identity=22.5308641975309, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789041, Length=323, Percent_Identity=24.4582043343653, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788711, Length=311, Percent_Identity=25.4019292604502, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40750; Mature: 40750

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKFATWYKIVTKHIRFFFSYSIPMFFKKAKNYINLPIIVVGLALIIGLFHLFSYLLPF
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
TDNAFVVTNVTPVAADVSGFITEIYVKNGQKVKKNDPIFSVYRIPYELAYQQAMADYKEG
CCCEEEEEECCHHHHHHHHHHHEEEECCCCEECCCCCEEEEEECCHHHHHHHHHHHHHHH
LKKIDVFQKQIERTVALIKATDAELEKAQFALGLKKNKNVAEAVSVLELKNLGYDVSTLS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHH
NKRNALQQEVAVLQAKIEQQRHTVASLKAKMDNAKVNLDLTIVRAPGDGVIDNMYVSPNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCEEECCCC
PIEIHKPVFSFIDTANYYIQANFNETDLRNVRQGDKAYIILRMYYFDKIFHGVVVNSLWA
CEEEHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
AERQSTAPKSQIQVVTNQNEWLLLPQRFPLQIKILDPDPDYPLNPGASAYVYISTKR
HHHHCCCCCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKEKFATWYKIVTKHIRFFFSYSIPMFFKKAKNYINLPIIVVGLALIIGLFHLFSYLLPF
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
TDNAFVVTNVTPVAADVSGFITEIYVKNGQKVKKNDPIFSVYRIPYELAYQQAMADYKEG
CCCEEEEEECCHHHHHHHHHHHEEEECCCCEECCCCCEEEEEECCHHHHHHHHHHHHHHH
LKKIDVFQKQIERTVALIKATDAELEKAQFALGLKKNKNVAEAVSVLELKNLGYDVSTLS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHH
NKRNALQQEVAVLQAKIEQQRHTVASLKAKMDNAKVNLDLTIVRAPGDGVIDNMYVSPNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCEEECCCC
PIEIHKPVFSFIDTANYYIQANFNETDLRNVRQGDKAYIILRMYYFDKIFHGVVVNSLWA
CEEEHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
AERQSTAPKSQIQVVTNQNEWLLLPQRFPLQIKILDPDPDYPLNPGASAYVYISTKR
HHHHCCCCCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]