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The map label for this gene is gpmA

Identifier: 54027163

GI number: 54027163

Start: 5487787

End: 5488524

Strand: Reverse

Name: gpmA

Synonym: nfa51890

Alternate gene names: 54027163

Gene position: 5488524-5487787 (Counterclockwise)

Preceding gene: 54027164

Following gene: 54027162

Centisome position: 91.15

GC content: 68.7

Gene sequence:

>738_bases
ATGACGTACACCCTCGTGCTGCTGCGCCACGGCGAGAGCGAATGGAACGCCCTGAACCTGTTCACCGGCTGGGTGGACGT
GCACCTCACCGACAAGGGCGTGGCCGAGGGCAAGCGGGCCGGTGAGCTGCTCGCCGAGCACGGGATCCTGCCCGACATCG
TCTACACCTCGCTGCTGCGCCGGGCCATCTCCACCGCCAACATCGCCCTCGACGCCGCCGACCGGCACTGGATCCCGGTC
GTGCGGGACTGGCGGCTCAACGAGCGGCACTACGGCGAGCTGCAGGGCAAGAACAAGGCCCAGATCCGCGACAAGTACGG
CGAGGAGCAGTTCATGCTGTGGCGGCGCAGCTACGACACCCCGCCGCCGCCCATCGAGGCGGGCAACGAGTACAGCCAGG
AGGGCGACGCCCGTTACGCGGGCATCGACATCCCCAAGACCGAGTGCCTGCTCGACGTGGTGAACCGGATGGTCCCCTAC
TGGGAGTCGACCATCTCCAAGGATCTGCTGGCGGGCAAGACCGTGCTGATCGCCGCGCACGGCAACTCGCTGCGCGCGCT
GGTCAAGCACCTCGACCAGATCTCCGACGAGGAGATCGCCGGTCTGAACATCCCGACCGGCATTCCGCTGCGCTACGAAC
TGGACGAGAACCTGCGTCCGGTGCGCCCCCGCGAGTACCTGGACCCGGAGGCGGCCGCCGCCGGCGCGGCCGCGGTCGCG
AGCCAGGGCGGTAAGTAA

Upstream 100 bases:

>100_bases
CCTCCGAACTCGGCGAGCAGGCCACGCTGGTGGGGGCGGGCCTGCTGACGGCGCTGGGCGGCCGCGGCTGAGTCGCCGCG
GCGTCGTTACACTACGCGGC

Downstream 100 bases:

>100_bases
CTCGTCGTTCGCGCGTGGGGCCCGGCGGATTCCGCCGGGCCCCACGTGTGTTCAGGCCCGTGTGTCGAGCTGTTGTCCAC
AGGGCACGGGTTGTCCACAC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTYTLVLLRHGESEWNALNLFTGWVDVHLTDKGVAEGKRAGELLAEHGILPDIVYTSLLRRAISTANIALDAADRHWIPV
VRDWRLNERHYGELQGKNKAQIRDKYGEEQFMLWRRSYDTPPPPIEAGNEYSQEGDARYAGIDIPKTECLLDVVNRMVPY
WESTISKDLLAGKTVLIAAHGNSLRALVKHLDQISDEEIAGLNIPTGIPLRYELDENLRPVRPREYLDPEAAAAGAAAVA
SQGGK

Sequences:

>Translated_245_residues
MTYTLVLLRHGESEWNALNLFTGWVDVHLTDKGVAEGKRAGELLAEHGILPDIVYTSLLRRAISTANIALDAADRHWIPV
VRDWRLNERHYGELQGKNKAQIRDKYGEEQFMLWRRSYDTPPPPIEAGNEYSQEGDARYAGIDIPKTECLLDVVNRMVPY
WESTISKDLLAGKTVLIAAHGNSLRALVKHLDQISDEEIAGLNIPTGIPLRYELDENLRPVRPREYLDPEAAAAGAAAVA
SQGGK
>Mature_244_residues
TYTLVLLRHGESEWNALNLFTGWVDVHLTDKGVAEGKRAGELLAEHGILPDIVYTSLLRRAISTANIALDAADRHWIPVV
RDWRLNERHYGELQGKNKAQIRDKYGEEQFMLWRRSYDTPPPPIEAGNEYSQEGDARYAGIDIPKTECLLDVVNRMVPYW
ESTISKDLLAGKTVLIAAHGNSLRALVKHLDQISDEEIAGLNIPTGIPLRYELDENLRPVRPREYLDPEAAAAGAAAVAS
QGGK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=248, Percent_Identity=49.5967741935484, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI4502445, Length=249, Percent_Identity=48.1927710843374, Blast_Score=237, Evalue=7e-63,
Organism=Homo sapiens, GI40353764, Length=249, Percent_Identity=48.1927710843374, Blast_Score=237, Evalue=7e-63,
Organism=Homo sapiens, GI4505753, Length=247, Percent_Identity=50.6072874493927, Blast_Score=230, Evalue=9e-61,
Organism=Homo sapiens, GI71274132, Length=247, Percent_Identity=48.1781376518219, Blast_Score=216, Evalue=1e-56,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=49.3827160493827, Blast_Score=141, Evalue=6e-34,
Organism=Escherichia coli, GI1786970, Length=226, Percent_Identity=53.5398230088496, Blast_Score=242, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6322697, Length=244, Percent_Identity=66.3934426229508, Blast_Score=318, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=34.4481605351171, Blast_Score=165, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324516, Length=293, Percent_Identity=33.1058020477816, Blast_Score=164, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24646216, Length=248, Percent_Identity=48.7903225806452, Blast_Score=238, Evalue=2e-63,
Organism=Drosophila melanogaster, GI85725270, Length=248, Percent_Identity=47.9838709677419, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI85725272, Length=248, Percent_Identity=47.9838709677419, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24650981, Length=248, Percent_Identity=47.9838709677419, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=40.4545454545455, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=40.4545454545455, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=40.4545454545455, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_NOCFA (Q5YP50)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_121405.1
- ProteinModelPortal:   Q5YP50
- SMR:   Q5YP50
- GeneID:   3110754
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa51890
- NMPDR:   fig|247156.1.peg.4986
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK14120
- BioCyc:   NFAR247156:NFA51890-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 27376; Mature: 27245

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 10-10 ACT_SITE 180-180

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTLVLLRHGESEWNALNLFTGWVDVHLTDKGVAEGKRAGELLAEHGILPDIVYTSLLR
CEEEEEEEECCCCCCCEEEEEEEEEEEEECCCCHHCHHHHHHHHHHCCCCHHHHHHHHHH
RAISTANIALDAADRHWIPVVRDWRLNERHYGELQGKNKAQIRDKYGEEQFMLWRRSYDT
HHHHHHHEEEECCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCC
PPPPIEAGNEYSQEGDARYAGIDIPKTECLLDVVNRMVPYWESTISKDLLAGKTVLIAAH
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GNSLRALVKHLDQISDEEIAGLNIPTGIPLRYELDENLRPVRPREYLDPEAAAAGAAAVA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCHHHHHHHHHHH
SQGGK
CCCCC
>Mature Secondary Structure 
TYTLVLLRHGESEWNALNLFTGWVDVHLTDKGVAEGKRAGELLAEHGILPDIVYTSLLR
EEEEEEEECCCCCCCEEEEEEEEEEEEECCCCHHCHHHHHHHHHHCCCCHHHHHHHHHH
RAISTANIALDAADRHWIPVVRDWRLNERHYGELQGKNKAQIRDKYGEEQFMLWRRSYDT
HHHHHHHEEEECCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCC
PPPPIEAGNEYSQEGDARYAGIDIPKTECLLDVVNRMVPYWESTISKDLLAGKTVLIAAH
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GNSLRALVKHLDQISDEEIAGLNIPTGIPLRYELDENLRPVRPREYLDPEAAAAGAAAVA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCHHHHHHHHHHH
SQGGK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA