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The map label for this gene is cocE [H]

Identifier: 54027162

GI number: 54027162

Start: 5485551

End: 5487602

Strand: Reverse

Name: cocE [H]

Synonym: nfa51880

Alternate gene names: 54027162

Gene position: 5487602-5485551 (Counterclockwise)

Preceding gene: 54027163

Following gene: 54027161

Centisome position: 91.14

GC content: 69.64

Gene sequence:

>2052_bases
ATGAGAAGAGCGTTCCGGGTCACCGTGGCGGGCCTCGCCGCCGCCCTGTTCCTGCCGTTCCTCGGCTCCGGCGCCACCGC
CGCGCCGCTGCCCACCGGGCCCGACGGTGGCGCGGCGGGCCAGGCATGGGCCGCGACCCACGACGGGCCGCAGCAGTTCC
CGAACATCCACATCACCTGGGATGTTCCGATCACCATGAGCGACGGCACGGTGCTGAAGGCGAATCTGTACCGCCCGGCC
GACGTGCTCGGCAATCCGGTCCCCGTCGCGACGCCGACGGTGGTCAACATGACGCCGTACACCAAGCTGGTGTCCAACCT
CGCCGACCACGCGGGCTCGGTGCCCGGCCTGTCGGACGCGATGATCGGGCTGTTCCGCGAGATCGACATGACCGGCACGC
CGTTCTCCGGCGTCACCGATCTCACCAAGGCCTTCGGGGGTGGCCAGCTGCGCAACTTCGCCGTCGACCGCAGCCTGGTC
CGCAGCGGCTACACCCAGCTGGTCGTCGACGTCCGCGGCACCGGCTTCTCGCAGGGCGAATGGGACATGCTGCGCGACCG
CGAGCAGCAGGACACCGTCGAGGTGATCGACTGGGCGGCCCGCCAGCCGTGGTCCAACGGCCGGATCGGCATGAGCGGCA
TCTCCTACTCCGCCATCAACCAGGTGCAGGCGGCGGAGAAGGCGCCGCCCGCGCTACAGGCCATCTTCCCGATCGTGCCG
GGCAGCGACCTGGTCACCGACGTGCTCGCGCCCGGCGGCGGCTTCGGGTTCAACTTCATCCCGCTGTGGCTGACCGCGAT
CAACACCCTCAAGTGGGTGCCGGACGTGCAGTCCCTGGTCACCGGCAACTTCGACCAGCAGTGGCTCACCGACCGCATGG
ACTCGCCACTGACCTACATGGACGTGTTCCTCAACGCCTACAGCAAGACCCGGCTCGAGGATCTGGACCCGCGGGTGCGC
AGCATGCTCACCGACGGCAGCCCCGAACGCAAGGCGTGGCTGGGTGATCCGAGCCGGATCACCATCCCGACCTTCGTCGT
CGGTGGCTGGCACGACCTGTTCACCTACTCCGAGTCCCAGATCTACAACCAGATCTCGGCGCCGCCCGGGCACAAGCAGC
TGTTGATGGGCAACACCTACCACCTGAACTCCGGCAACGAATACGCCGAGCCCGGTCTGCCACCCCGGCTGGACGTGCTG
CAGCGGGCGTGGTTCGACCGCTGGCTCAAGGACATCGACAACGGGATCGATCGCTACGGTCCGGTCACGCTGCGCCAGCA
GGGCGGTGGCTGGATCACCCAGAACGGCTTCGGCGACTCGGCCGAGGGTGCGGAGGTCGCCGAGCATCGGCGCATGTACC
TGTCGGGAGCGCCGAGCGGTACCGCGCGCAGCGTGTACGACGGCTCGCTGCTGGCCGAGCAGGACGGCAGCACCCAGCGC
CTCACCGTCGCGCCGGGCCTGACCGGCCTGTGCTCGAACGACGCGGGCCAGGCCACCGCGGGCGTGCTCGCCGCCATCGA
CGCCTGCGGTGCCGATTCGCGGATCCAGGAGACCAACGGCCTCACCTTCACCAGTGCGCCGGTGGCCGAGCCGACCGTCA
TCTCCGGGCCGATCGCGGTGCGGTTGAACACGGTGCAGGACGCCGCCGACGGCTACTGGTCGGTGACGGTCAACGACGTC
GCGCCCGACGGTCGCTCCACGGTGCTGTCCTCGGGCCAGTTGATGGCCTCGTTGCGGTCGATCGACGAGTCGCGCAGCAG
CCGCTCCGCCAACGGCGACTACACCGATCCGCGGCCGTTGGCCTCCCTGGAGGACCGGCTCCCGGTGATCCCGGGTGAGC
CGACCACCCTCGACATCGCGCTGCCCGCCACCGAGGCGGTACTGCAACCGGGCCACCGGCTGCGGGTGGACGTGTACGCG
GGCAACTTCCCGAAGGGCCTGCCGATCCTGCCCATGCTCGTCGACACCGGGCTGAAGCCGCAGCACCTACAGCTGGACCC
GCAGCGGCCCAGTTTCGTGAACATCCCGGTCCGCGGCAACCCCGGCTGGTAA

Upstream 100 bases:

>100_bases
CACGGGTTGTCCACACTGTGGTGGGTCACGTCTTCTTACCGGCGAGTAAGTGTGCAAGAATTCCGCCGTCCCATTTCAAA
GGAGAGGTGGACCACTCGCG

Downstream 100 bases:

>100_bases
CCGCGACGGCGCCGCCGAATCCGGCGGCGCCGTCTGCGTTTCGACCGACACGCCGCGCCGCCGCCCGCGTGGCGAACGGC
GGGTAAACACCTGCCCAACA

Product: putative peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MRRAFRVTVAGLAAALFLPFLGSGATAAPLPTGPDGGAAGQAWAATHDGPQQFPNIHITWDVPITMSDGTVLKANLYRPA
DVLGNPVPVATPTVVNMTPYTKLVSNLADHAGSVPGLSDAMIGLFREIDMTGTPFSGVTDLTKAFGGGQLRNFAVDRSLV
RSGYTQLVVDVRGTGFSQGEWDMLRDREQQDTVEVIDWAARQPWSNGRIGMSGISYSAINQVQAAEKAPPALQAIFPIVP
GSDLVTDVLAPGGGFGFNFIPLWLTAINTLKWVPDVQSLVTGNFDQQWLTDRMDSPLTYMDVFLNAYSKTRLEDLDPRVR
SMLTDGSPERKAWLGDPSRITIPTFVVGGWHDLFTYSESQIYNQISAPPGHKQLLMGNTYHLNSGNEYAEPGLPPRLDVL
QRAWFDRWLKDIDNGIDRYGPVTLRQQGGGWITQNGFGDSAEGAEVAEHRRMYLSGAPSGTARSVYDGSLLAEQDGSTQR
LTVAPGLTGLCSNDAGQATAGVLAAIDACGADSRIQETNGLTFTSAPVAEPTVISGPIAVRLNTVQDAADGYWSVTVNDV
APDGRSTVLSSGQLMASLRSIDESRSSRSANGDYTDPRPLASLEDRLPVIPGEPTTLDIALPATEAVLQPGHRLRVDVYA
GNFPKGLPILPMLVDTGLKPQHLQLDPQRPSFVNIPVRGNPGW

Sequences:

>Translated_683_residues
MRRAFRVTVAGLAAALFLPFLGSGATAAPLPTGPDGGAAGQAWAATHDGPQQFPNIHITWDVPITMSDGTVLKANLYRPA
DVLGNPVPVATPTVVNMTPYTKLVSNLADHAGSVPGLSDAMIGLFREIDMTGTPFSGVTDLTKAFGGGQLRNFAVDRSLV
RSGYTQLVVDVRGTGFSQGEWDMLRDREQQDTVEVIDWAARQPWSNGRIGMSGISYSAINQVQAAEKAPPALQAIFPIVP
GSDLVTDVLAPGGGFGFNFIPLWLTAINTLKWVPDVQSLVTGNFDQQWLTDRMDSPLTYMDVFLNAYSKTRLEDLDPRVR
SMLTDGSPERKAWLGDPSRITIPTFVVGGWHDLFTYSESQIYNQISAPPGHKQLLMGNTYHLNSGNEYAEPGLPPRLDVL
QRAWFDRWLKDIDNGIDRYGPVTLRQQGGGWITQNGFGDSAEGAEVAEHRRMYLSGAPSGTARSVYDGSLLAEQDGSTQR
LTVAPGLTGLCSNDAGQATAGVLAAIDACGADSRIQETNGLTFTSAPVAEPTVISGPIAVRLNTVQDAADGYWSVTVNDV
APDGRSTVLSSGQLMASLRSIDESRSSRSANGDYTDPRPLASLEDRLPVIPGEPTTLDIALPATEAVLQPGHRLRVDVYA
GNFPKGLPILPMLVDTGLKPQHLQLDPQRPSFVNIPVRGNPGW
>Mature_683_residues
MRRAFRVTVAGLAAALFLPFLGSGATAAPLPTGPDGGAAGQAWAATHDGPQQFPNIHITWDVPITMSDGTVLKANLYRPA
DVLGNPVPVATPTVVNMTPYTKLVSNLADHAGSVPGLSDAMIGLFREIDMTGTPFSGVTDLTKAFGGGQLRNFAVDRSLV
RSGYTQLVVDVRGTGFSQGEWDMLRDREQQDTVEVIDWAARQPWSNGRIGMSGISYSAINQVQAAEKAPPALQAIFPIVP
GSDLVTDVLAPGGGFGFNFIPLWLTAINTLKWVPDVQSLVTGNFDQQWLTDRMDSPLTYMDVFLNAYSKTRLEDLDPRVR
SMLTDGSPERKAWLGDPSRITIPTFVVGGWHDLFTYSESQIYNQISAPPGHKQLLMGNTYHLNSGNEYAEPGLPPRLDVL
QRAWFDRWLKDIDNGIDRYGPVTLRQQGGGWITQNGFGDSAEGAEVAEHRRMYLSGAPSGTARSVYDGSLLAEQDGSTQR
LTVAPGLTGLCSNDAGQATAGVLAAIDACGADSRIQETNGLTFTSAPVAEPTVISGPIAVRLNTVQDAADGYWSVTVNDV
APDGRSTVLSSGQLMASLRSIDESRSSRSANGDYTDPRPLASLEDRLPVIPGEPTTLDIALPATEAVLQPGHRLRVDVYA
GNFPKGLPILPMLVDTGLKPQHLQLDPQRPSFVNIPVRGNPGW

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 73310; Mature: 73310

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAFRVTVAGLAAALFLPFLGSGATAAPLPTGPDGGAAGQAWAATHDGPQQFPNIHITW
CCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEE
DVPITMSDGTVLKANLYRPADVLGNPVPVATPTVVNMTPYTKLVSNLADHAGSVPGLSDA
EEEEEECCCCEEEEECCCCHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCHHHH
MIGLFREIDMTGTPFSGVTDLTKAFGGGQLRNFAVDRSLVRSGYTQLVVDVRGTGFSQGE
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
WDMLRDREQQDTVEVIDWAARQPWSNGRIGMSGISYSAINQVQAAEKAPPALQAIFPIVP
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCC
GSDLVTDVLAPGGGFGFNFIPLWLTAINTLKWVPDVQSLVTGNFDQQWLTDRMDSPLTYM
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHCCCCHHHH
DVFLNAYSKTRLEDLDPRVRSMLTDGSPERKAWLGDPSRITIPTFVVGGWHDLFTYSESQ
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEECCCCCEEEEEEEEECCCHHHHHCCHHH
IYNQISAPPGHKQLLMGNTYHLNSGNEYAEPGLPPRLDVLQRAWFDRWLKDIDNGIDRYG
HHHHHCCCCCCCEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PVTLRQQGGGWITQNGFGDSAEGAEVAEHRRMYLSGAPSGTARSVYDGSLLAEQDGSTQR
CEEEEECCCCEEEECCCCCCCCCHHHHHHHHEEEECCCCCCCCEECCCCEEECCCCCCEE
LTVAPGLTGLCSNDAGQATAGVLAAIDACGADSRIQETNGLTFTSAPVAEPTVISGPIAV
EEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHCCCEEEECCCCCCCEEECCCEEE
RLNTVQDAADGYWSVTVNDVAPDGRSTVLSSGQLMASLRSIDESRSSRSANGDYTDPRPL
EEECHHHCCCCEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ASLEDRLPVIPGEPTTLDIALPATEAVLQPGHRLRVDVYAGNFPKGLPILPMLVDTGLKP
HHHHHCCCCCCCCCCEEEEECCCHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHCCCCCC
QHLQLDPQRPSFVNIPVRGNPGW
CEEEECCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRRAFRVTVAGLAAALFLPFLGSGATAAPLPTGPDGGAAGQAWAATHDGPQQFPNIHITW
CCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEE
DVPITMSDGTVLKANLYRPADVLGNPVPVATPTVVNMTPYTKLVSNLADHAGSVPGLSDA
EEEEEECCCCEEEEECCCCHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCHHHH
MIGLFREIDMTGTPFSGVTDLTKAFGGGQLRNFAVDRSLVRSGYTQLVVDVRGTGFSQGE
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
WDMLRDREQQDTVEVIDWAARQPWSNGRIGMSGISYSAINQVQAAEKAPPALQAIFPIVP
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCC
GSDLVTDVLAPGGGFGFNFIPLWLTAINTLKWVPDVQSLVTGNFDQQWLTDRMDSPLTYM
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHCCCCHHHH
DVFLNAYSKTRLEDLDPRVRSMLTDGSPERKAWLGDPSRITIPTFVVGGWHDLFTYSESQ
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEECCCCCEEEEEEEEECCCHHHHHCCHHH
IYNQISAPPGHKQLLMGNTYHLNSGNEYAEPGLPPRLDVLQRAWFDRWLKDIDNGIDRYG
HHHHHCCCCCCCEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PVTLRQQGGGWITQNGFGDSAEGAEVAEHRRMYLSGAPSGTARSVYDGSLLAEQDGSTQR
CEEEEECCCCEEEECCCCCCCCCHHHHHHHHEEEECCCCCCCCEECCCCEEECCCCCCEE
LTVAPGLTGLCSNDAGQATAGVLAAIDACGADSRIQETNGLTFTSAPVAEPTVISGPIAV
EEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHCCCEEEECCCCCCCEEECCCEEE
RLNTVQDAADGYWSVTVNDVAPDGRSTVLSSGQLMASLRSIDESRSSRSANGDYTDPRPL
EEECHHHCCCCEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ASLEDRLPVIPGEPTTLDIALPATEAVLQPGHRLRVDVYAGNFPKGLPILPMLVDTGLKP
HHHHHCCCCCCCCCCEEEEECCCHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHCCCCCC
QHLQLDPQRPSFVNIPVRGNPGW
CEEEECCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]