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The map label for this gene is nagC [H]

Identifier: 54027164

GI number: 54027164

Start: 5488554

End: 5489447

Strand: Reverse

Name: nagC [H]

Synonym: nfa51900

Alternate gene names: 54027164

Gene position: 5489447-5488554 (Counterclockwise)

Preceding gene: 54027165

Following gene: 54027163

Centisome position: 91.17

GC content: 75.06

Gene sequence:

>894_bases
ATGACGGTTCTCGCACTGGACATCGGCGCCACCAAGATCGCGGTGGGGCTGGTCGGCGCCGACGGGGTGACCCACGAGGT
GGGCCGGATCCGGGTGCCCGAGAGCGGGGTGTGGGAGGCGGTGTCCGGACTGCTGCTCGCGGCCGCCAACGGCCACGAGG
TGGCGGTCGTCGGGATCGGGTCGTGCGGCCCGGTGGACGCGCCCGCCGGGATCACCACCCCGCTCAACATTCCCGAGTGG
CGCGAGGGGTTCGCCCTGGTCGACGCGGTGCGCGAACTGTTTCCCGGCGCCTCGGTGCGGATGGCCATCGACGGGGTGTG
CCTCGCGCTGGCCGAGCGGCACTTCGGCGCGGCGCGGGAGACCCCGGACGCGCTCGCCATGACGGTGTCCTCGGGAATCG
GGGGCGGGATCATCGTCGGCGGCATGGTCGCGGTCGGGCACACCGGCAACGCCGGGCACATCGGGCACATGATCGTGCCG
GGGAGCACCGATCCCTGCGCGTGCGGCGGTGTCGGCTGCGTGGAGGCCGTGGCGAGCGGACCCTCGGCGGTGCGCTGGGC
TCGGGAGCGGGGCTGGACCGGCAGCGACGGCGTCGAACTGGCGGCCGCCGCGCAGGCCGGTGACCGGATCGCCAAGGCCG
CCCTGCGGCGCGCCGGAATCGCGCTGGGACAGGTCATCTCGTCGGCGGCCGCGCTGCTGGACGTGGACCTGGTGGTGGTC
GGCGGTGGTTTCGCCCAGTCCGGCGAGCCGCTGTGGCGGCCGCTGCAGGAAGCCCTCGGCGCGCACGCGCGCATCGAGTT
CCTCGGCGATCTGCGGGTGGTGCCCTCCGAACTCGGCGAGCAGGCCACGCTGGTGGGGGCGGGCCTGCTGACGGCGCTGG
GCGGCCGCGGCTGA

Upstream 100 bases:

>100_bases
CAACCACGTAGCGTTACCGCCCGACACGAACATGCACGCACCGGGCCGCCGCCGTGCGCGGCGGTCCGGTGCTGCCTGGG
CAGTTGGGGGTTTTGGGCAG

Downstream 100 bases:

>100_bases
GTCGCCGCGGCGTCGTTACACTACGCGGCATGACGTACACCCTCGTGCTGCTGCGCCACGGCGAGAGCGAATGGAACGCC
CTGAACCTGTTCACCGGCTG

Product: putative sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTVLALDIGATKIAVGLVGADGVTHEVGRIRVPESGVWEAVSGLLLAAANGHEVAVVGIGSCGPVDAPAGITTPLNIPEW
REGFALVDAVRELFPGASVRMAIDGVCLALAERHFGAARETPDALAMTVSSGIGGGIIVGGMVAVGHTGNAGHIGHMIVP
GSTDPCACGGVGCVEAVASGPSAVRWARERGWTGSDGVELAAAAQAGDRIAKAALRRAGIALGQVISSAAALLDVDLVVV
GGGFAQSGEPLWRPLQEALGAHARIEFLGDLRVVPSELGEQATLVGAGLLTALGGRG

Sequences:

>Translated_297_residues
MTVLALDIGATKIAVGLVGADGVTHEVGRIRVPESGVWEAVSGLLLAAANGHEVAVVGIGSCGPVDAPAGITTPLNIPEW
REGFALVDAVRELFPGASVRMAIDGVCLALAERHFGAARETPDALAMTVSSGIGGGIIVGGMVAVGHTGNAGHIGHMIVP
GSTDPCACGGVGCVEAVASGPSAVRWARERGWTGSDGVELAAAAQAGDRIAKAALRRAGIALGQVISSAAALLDVDLVVV
GGGFAQSGEPLWRPLQEALGAHARIEFLGDLRVVPSELGEQATLVGAGLLTALGGRG
>Mature_296_residues
TVLALDIGATKIAVGLVGADGVTHEVGRIRVPESGVWEAVSGLLLAAANGHEVAVVGIGSCGPVDAPAGITTPLNIPEWR
EGFALVDAVRELFPGASVRMAIDGVCLALAERHFGAARETPDALAMTVSSGIGGGIIVGGMVAVGHTGNAGHIGHMIVPG
STDPCACGGVGCVEAVASGPSAVRWARERGWTGSDGVELAAAAQAGDRIAKAALRRAGIALGQVISSAAALLDVDLVVVG
GGFAQSGEPLWRPLQEALGAHARIEFLGDLRVVPSELGEQATLVGAGLLTALGGRG

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=212, Percent_Identity=29.2452830188679, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081733, Length=256, Percent_Identity=27.34375, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787363, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082230, Length=248, Percent_Identity=33.8709677419355, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787878, Length=244, Percent_Identity=23.3606557377049, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 29539; Mature: 29408

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01125 ROK ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLALDIGATKIAVGLVGADGVTHEVGRIRVPESGVWEAVSGLLLAAANGHEVAVVGIG
CEEEEEECCCEEEEEEEECCCCCEECCCEEECCCCCHHHHHHHHEEEECCCCEEEEEEEC
SCGPVDAPAGITTPLNIPEWREGFALVDAVRELFPGASVRMAIDGVCLALAERHFGAARE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCC
TPDALAMTVSSGIGGGIIVGGMVAVGHTGNAGHIGHMIVPGSTDPCACGGVGCVEAVASG
CCHHHEEEHHCCCCCCEEEECEEEECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCC
PSAVRWARERGWTGSDGVELAAAAQAGDRIAKAALRRAGIALGQVISSAAALLDVDLVVV
CHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
GGGFAQSGEPLWRPLQEALGAHARIEFLGDLRVVPSELGEQATLVGAGLLTALGGRG
ECCCCCCCCHHHHHHHHHCCCCEEEEECCCCEECHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TVLALDIGATKIAVGLVGADGVTHEVGRIRVPESGVWEAVSGLLLAAANGHEVAVVGIG
EEEEEECCCEEEEEEEECCCCCEECCCEEECCCCCHHHHHHHHEEEECCCCEEEEEEEC
SCGPVDAPAGITTPLNIPEWREGFALVDAVRELFPGASVRMAIDGVCLALAERHFGAARE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCC
TPDALAMTVSSGIGGGIIVGGMVAVGHTGNAGHIGHMIVPGSTDPCACGGVGCVEAVASG
CCHHHEEEHHCCCCCCEEEECEEEECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCC
PSAVRWARERGWTGSDGVELAAAAQAGDRIAKAALRRAGIALGQVISSAAALLDVDLVVV
CHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
GGGFAQSGEPLWRPLQEALGAHARIEFLGDLRVVPSELGEQATLVGAGLLTALGGRG
ECCCCCCCCHHHHHHHHHCCCCEEEEECCCCEECHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]