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The map label for this gene is syrD [H]

Identifier: 54026902

GI number: 54026902

Start: 5147578

End: 5149389

Strand: Reverse

Name: syrD [H]

Synonym: nfa49280

Alternate gene names: 54026902

Gene position: 5149389-5147578 (Counterclockwise)

Preceding gene: 54026903

Following gene: 54026900

Centisome position: 85.52

GC content: 69.87

Gene sequence:

>1812_bases
ATGCAACTCCTCCGATTTCTCGTATCGATCTCCTGGGCGCGCATCGTCGCGGTCGTCGCCGCGGGCCTGGTGTGCGGTGC
GGCGAACACCTATCTGGTCACCCTGATCAACGGGGTGGTCTCGCCCGCGCCGCATCCGCGGGTCACCCTGGCGCAGTTCG
CGCTCACCGGGCTGGTGGTGCTGGTCAGCGGCCTGCTGTCGCAGGTGCTGCTGATCCGGTTGGCGCAGGACGCCATCTAC
CGGCTGCGGGCCGACCTGAGTTCGAGCGTGGTGGCCGCGCCGCTCGAGCATCTGGAACGGCTCGGCACGCACCGCCTGGT
GGCCACCCTCACCGAGGACGTGCGGGCGCTCTCCCAGGCGGTGACGGCGATTCCGGCGATCTGCATCGACGTGGCGACCA
TCATCGGCTGCTTCGTCTACCTCGCGATGGTCTCCGGACCGATCTTCGCGATCACCATCGCGGGCACGCTGCTCGGGGTC
GCCTGCGTCGAGCTGTTCCTCGGCCGGGTGCGGCGCATCTACCGTGACGCCAGGGAGAACGAGGACGCGCTGCTGCGTTC
GTTCCAGTCGGTCACCCTGGGGATCAAGGAACTCAAGCTGCACCGCGGCAGGCGCCGCGACTTCATGGACCGGCACCTGC
TCGGCGCCGCCCGCGACCTGCGCACGCAGAACGTCGACGCCGGCTCGAAGTTCTCGGTGGCCCAGGGGCTCGGCCAGCTG
CTGCAACTGGCGACGATGGCGCTGATCCTGTTCGCGGTGGCCGCCGCGATGGACCTGCCGCGCGAGGTGATGATCGGCTA
CGTACTGGTGACCACGTTCCTGGCGATGCCGATGCAGAACTTCATGCACCGCATCCCGGACCTGCTGCGCGGCGACGTGG
CGCTGGCCAAGATCCGCGCGATGAACCTGTCGCTGGAGACCATGCACGACGAGGAGCAGCTGCCCTACGCGCAGCGTCCC
GCCGTCGAGTCGGCGCGGCTCGAGCTCGCCGGGGTGGAGTACAGCTACCGGCAGGACGCGCCGCCGCAGTTCCCGCCGGG
CCCGCCCGGACCGCATCCCGGCGGCAGGCCGCCGCTGCCGCCGCCCGGCGCCGGCGGGCTGCCGCCGCAGGGTCCGCCCG
ACGTGAACGGTCATCGCACGGTCAGCCACGCGGGCGCCGACGGCAGACCGGTGCCGCTCGGACCGCCGCCGCCCGGCGCC
GAGGACGAGTCCGGCTTCCGGCTCGGCCCGGTGGATCTGGTGTTCGAGCCGGGGCAGATCACCTTCGTGGTCGGCGGCAA
CGGCAGCGGCAAATCCACGCTGGCCAAGCTGATCACCGGACTGTATGTGCCGCGCGCGGGCACGGTGCGACTCAACGGCG
AGCCGATCGATCACCAGAACATCGAGTGGTTCCGGCAGAACACCTCGGCGGTGTTCACCGACTTCCACCTCTTCGAGGAG
TACCTCGGGTTCGACGGCCCTGGTGTCGACGACGAGGTGCGGCGGTACCTGCGCGAGTTGCGGCTCGACGACAAGGTGAC
GGTGCGGGACGGGAAGCTCTCGACCGTGGCGCTGTCGCAGGGTCAGCGCAAGCGGCTCGCGCTGCTGACGGCACTGCTGG
AGGACCGGCCGATCTACGTGTTCGACGAGTGGGCGGCCGATCAGGAACCGAAGTTCCGCGAGGTGTTCTACCGGGAGATC
CTCGACGGGCTCAAGCGGCGCGGGAAGACGGTCATCGTCATCACCCACGACGACCGGTACTTCGACCGCGCCGACCGGCT
GGTGAAGCTGGATTTCGGCCGGGTGGTGGATCCGGTCACCGTGCCCGGCTGA

Upstream 100 bases:

>100_bases
GCGACCGCCGAACCCATCTCGACGGGTGTGGCGTTCTCCTTCGCGCCCGGGGTCACGCTCGAGGGCCTGATCTTCGACAT
CATCCGTCGCTGAGGCCGTC

Downstream 100 bases:

>100_bases
CACCCGGCCGCCGCGGGCCGGTGACTCCGCCGACGGGCGGGGTCACCGGGCTCGGTCATCTCCGTCGGTTCCCGGCCGTC
ATCTCGGCCACCCGGGTCGC

Product: putative ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MQLLRFLVSISWARIVAVVAAGLVCGAANTYLVTLINGVVSPAPHPRVTLAQFALTGLVVLVSGLLSQVLLIRLAQDAIY
RLRADLSSSVVAAPLEHLERLGTHRLVATLTEDVRALSQAVTAIPAICIDVATIIGCFVYLAMVSGPIFAITIAGTLLGV
ACVELFLGRVRRIYRDARENEDALLRSFQSVTLGIKELKLHRGRRRDFMDRHLLGAARDLRTQNVDAGSKFSVAQGLGQL
LQLATMALILFAVAAAMDLPREVMIGYVLVTTFLAMPMQNFMHRIPDLLRGDVALAKIRAMNLSLETMHDEEQLPYAQRP
AVESARLELAGVEYSYRQDAPPQFPPGPPGPHPGGRPPLPPPGAGGLPPQGPPDVNGHRTVSHAGADGRPVPLGPPPPGA
EDESGFRLGPVDLVFEPGQITFVVGGNGSGKSTLAKLITGLYVPRAGTVRLNGEPIDHQNIEWFRQNTSAVFTDFHLFEE
YLGFDGPGVDDEVRRYLRELRLDDKVTVRDGKLSTVALSQGQRKRLALLTALLEDRPIYVFDEWAADQEPKFREVFYREI
LDGLKRRGKTVIVITHDDRYFDRADRLVKLDFGRVVDPVTVPG

Sequences:

>Translated_603_residues
MQLLRFLVSISWARIVAVVAAGLVCGAANTYLVTLINGVVSPAPHPRVTLAQFALTGLVVLVSGLLSQVLLIRLAQDAIY
RLRADLSSSVVAAPLEHLERLGTHRLVATLTEDVRALSQAVTAIPAICIDVATIIGCFVYLAMVSGPIFAITIAGTLLGV
ACVELFLGRVRRIYRDARENEDALLRSFQSVTLGIKELKLHRGRRRDFMDRHLLGAARDLRTQNVDAGSKFSVAQGLGQL
LQLATMALILFAVAAAMDLPREVMIGYVLVTTFLAMPMQNFMHRIPDLLRGDVALAKIRAMNLSLETMHDEEQLPYAQRP
AVESARLELAGVEYSYRQDAPPQFPPGPPGPHPGGRPPLPPPGAGGLPPQGPPDVNGHRTVSHAGADGRPVPLGPPPPGA
EDESGFRLGPVDLVFEPGQITFVVGGNGSGKSTLAKLITGLYVPRAGTVRLNGEPIDHQNIEWFRQNTSAVFTDFHLFEE
YLGFDGPGVDDEVRRYLRELRLDDKVTVRDGKLSTVALSQGQRKRLALLTALLEDRPIYVFDEWAADQEPKFREVFYREI
LDGLKRRGKTVIVITHDDRYFDRADRLVKLDFGRVVDPVTVPG
>Mature_603_residues
MQLLRFLVSISWARIVAVVAAGLVCGAANTYLVTLINGVVSPAPHPRVTLAQFALTGLVVLVSGLLSQVLLIRLAQDAIY
RLRADLSSSVVAAPLEHLERLGTHRLVATLTEDVRALSQAVTAIPAICIDVATIIGCFVYLAMVSGPIFAITIAGTLLGV
ACVELFLGRVRRIYRDARENEDALLRSFQSVTLGIKELKLHRGRRRDFMDRHLLGAARDLRTQNVDAGSKFSVAQGLGQL
LQLATMALILFAVAAAMDLPREVMIGYVLVTTFLAMPMQNFMHRIPDLLRGDVALAKIRAMNLSLETMHDEEQLPYAQRP
AVESARLELAGVEYSYRQDAPPQFPPGPPGPHPGGRPPLPPPGAGGLPPQGPPDVNGHRTVSHAGADGRPVPLGPPPPGA
EDESGFRLGPVDLVFEPGQITFVVGGNGSGKSTLAKLITGLYVPRAGTVRLNGEPIDHQNIEWFRQNTSAVFTDFHLFEE
YLGFDGPGVDDEVRRYLRELRLDDKVTVRDGKLSTVALSQGQRKRLALLTALLEDRPIYVFDEWAADQEPKFREVFYREI
LDGLKRRGKTVIVITHDDRYFDRADRLVKLDFGRVVDPVTVPG

Specific function: ATP-driven efflux pump necessary for the secretion of syringomycin. May specifically bind syringomycin and translocate it to the periplasmic space. SyrD is also required for full expression of the syrB gene [H]

COG id: COG4615

COG function: function code QP; ABC-type siderophore export system, fused ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI171184400, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI42741659, Length=201, Percent_Identity=31.3432835820896, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI9961252, Length=203, Percent_Identity=29.064039408867, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4505771, Length=203, Percent_Identity=29.064039408867, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI9961250, Length=203, Percent_Identity=29.064039408867, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI73747915, Length=253, Percent_Identity=26.8774703557312, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI25914749, Length=240, Percent_Identity=28.75, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788540, Length=199, Percent_Identity=44.2211055276382, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787112, Length=214, Percent_Identity=29.4392523364486, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787143, Length=237, Percent_Identity=29.535864978903, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787029, Length=202, Percent_Identity=26.7326732673267, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789873, Length=202, Percent_Identity=28.7128712871287, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1789672, Length=210, Percent_Identity=28.0952380952381, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786253, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788225, Length=210, Percent_Identity=29.5238095238095, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788450, Length=204, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI87081834, Length=213, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789032, Length=215, Percent_Identity=29.7674418604651, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790739, Length=220, Percent_Identity=27.7272727272727, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787105, Length=209, Percent_Identity=27.7511961722488, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787712, Length=193, Percent_Identity=25.9067357512953, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI48994943, Length=190, Percent_Identity=25.7894736842105, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=201, Percent_Identity=29.3532338308458, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115533592, Length=171, Percent_Identity=32.7485380116959, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17567269, Length=204, Percent_Identity=27.9411764705882, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567265, Length=205, Percent_Identity=26.3414634146341, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115535101, Length=204, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=203, Percent_Identity=29.064039408867, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71992290, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643674, Length=183, Percent_Identity=30.6010928961749, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI23397593, Length=205, Percent_Identity=33.1707317073171, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641565, Length=203, Percent_Identity=33.4975369458128, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24666092, Length=177, Percent_Identity=30.5084745762712, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24659289, Length=201, Percent_Identity=29.3532338308458, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281363262, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24653245, Length=243, Percent_Identity=27.9835390946502, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR005898 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 65935; Mature: 65935

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLRFLVSISWARIVAVVAAGLVCGAANTYLVTLINGVVSPAPHPRVTLAQFALTGLVV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LVSGLLSQVLLIRLAQDAIYRLRADLSSSVVAAPLEHLERLGTHRLVATLTEDVRALSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTAIPAICIDVATIIGCFVYLAMVSGPIFAITIAGTLLGVACVELFLGRVRRIYRDAREN
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EDALLRSFQSVTLGIKELKLHRGRRRDFMDRHLLGAARDLRTQNVDAGSKFSVAQGLGQL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LQLATMALILFAVAAAMDLPREVMIGYVLVTTFLAMPMQNFMHRIPDLLRGDVALAKIRA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MNLSLETMHDEEQLPYAQRPAVESARLELAGVEYSYRQDAPPQFPPGPPGPHPGGRPPLP
HCCCHHHCCCHHHCCCCCCCCHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPGAGGLPPQGPPDVNGHRTVSHAGADGRPVPLGPPPPGAEDESGFRLGPVDLVFEPGQI
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEECCEEEEECCCEE
TFVVGGNGSGKSTLAKLITGLYVPRAGTVRLNGEPIDHQNIEWFRQNTSAVFTDFHLFEE
EEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHH
YLGFDGPGVDDEVRRYLRELRLDDKVTVRDGKLSTVALSQGQRKRLALLTALLEDRPIYV
HHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEE
FDEWAADQEPKFREVFYREILDGLKRRGKTVIVITHDDRYFDRADRLVKLDFGRVVDPVT
EECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCEEEEECCCCCCCCC
VPG
CCC
>Mature Secondary Structure
MQLLRFLVSISWARIVAVVAAGLVCGAANTYLVTLINGVVSPAPHPRVTLAQFALTGLVV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LVSGLLSQVLLIRLAQDAIYRLRADLSSSVVAAPLEHLERLGTHRLVATLTEDVRALSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTAIPAICIDVATIIGCFVYLAMVSGPIFAITIAGTLLGVACVELFLGRVRRIYRDAREN
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EDALLRSFQSVTLGIKELKLHRGRRRDFMDRHLLGAARDLRTQNVDAGSKFSVAQGLGQL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LQLATMALILFAVAAAMDLPREVMIGYVLVTTFLAMPMQNFMHRIPDLLRGDVALAKIRA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MNLSLETMHDEEQLPYAQRPAVESARLELAGVEYSYRQDAPPQFPPGPPGPHPGGRPPLP
HCCCHHHCCCHHHCCCCCCCCHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPGAGGLPPQGPPDVNGHRTVSHAGADGRPVPLGPPPPGAEDESGFRLGPVDLVFEPGQI
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEECCEEEEECCCEE
TFVVGGNGSGKSTLAKLITGLYVPRAGTVRLNGEPIDHQNIEWFRQNTSAVFTDFHLFEE
EEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHH
YLGFDGPGVDDEVRRYLRELRLDDKVTVRDGKLSTVALSQGQRKRLALLTALLEDRPIYV
HHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEE
FDEWAADQEPKFREVFYREILDGLKRRGKTVIVITHDDRYFDRADRLVKLDFGRVVDPVT
EECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCEEEEECCCCCCCCC
VPG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8231810 [H]