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The map label for this gene is pimC [H]

Identifier: 54026889

GI number: 54026889

Start: 5131548

End: 5132675

Strand: Reverse

Name: pimC [H]

Synonym: nfa49150

Alternate gene names: 54026889

Gene position: 5132675-5131548 (Counterclockwise)

Preceding gene: 54026890

Following gene: 54026885

Centisome position: 85.24

GC content: 75.53

Gene sequence:

>1128_bases
GTGCGCATCGTGCAGCTGGCCAACTTCTACGGCCCCCGCTCGGGTGGGTTGCGAACCGCGCTGCACCACCTGGGCGCCGG
GTACGTCGCCGCCGGGCACGAGGTGGTGCTGATCGTGCCGGGACCGCGCAGGCGCGAAGAGGTGTTGCCCGGCGGCGCCG
TGCGGATCACCCTGCCCGCCCTGCCCATCCCGTGGACCGGCGGCTACCGCGCCGCCGACCCGCGCCGCGTCGCCGACGTG
CTCACCGGCCTGCGCCCCGACGTGCTCGAGGTCTCCGATCGGCTCACCCTGCGCGGCTTCGGCCGCTGGGCCCGCCGCCG
CGACGTGGCCGGCGTGATGATCTCCCACGAACGCCTCGACCGGCTGCTCGGCCAGGTACTGCCCGGCCCGCTGGCCCGCC
GCTGCGCCGACATCGCCAACCGCCACACCGCCGCCGACTACGACATCGTCGTGTGCACCACCGAATTCGCCCGCGCCGAA
TTCCGCCGCATCGGCGCGCCCAACGTGGAACTGGTGCCGCTGGGCGTCGACCTCGACCTGTTCAGCCCCCGCCGCCGCGA
CGGCCGCCTGCGCGCCGACCTCGCCGCACCCGGTCACCCGCTGCTGGTGCACTGCGGACGGCTGTCGGTGGAGAAACGCG
TCGACCGCAGCATCGAGGCCGTCGGCGAACTCAACCGGGCCGGTGCACCGGTCCGCCTGGTCGTCGCCGGCGACGGACCT
CGCCGCGACGCGCTGGAGAAACGCGCCCGCAGCGTGCCCGCCCTGCCCGACGGCAGGCCCGCCGTCCACTTCACCGGCTT
CATCTCCGACCGCCACCGGGTCGCCACCCTGCTCGCCACCGCCGACGTCTCCCTCGCCCCCGGCCCGCACGAAACCTTCG
GGCTGGCCGCCCTCGAAGCCCTCGCCGCGGGCACCCCCGTCGTCGCCAGCCGCTCCTCGGCCCTCGCCGACATCGTCACC
GCCGACTGCGGCGCCATCGCCGACGACGACCCCGCCGCCTTCGCCACCGCCGTCACCGACATCCTCGCCCGCCCCCCGGC
CACCCGCCGCCGCGCCGCCCGCCACCGCGCCGAACAATTCACCTGGGGGAGAGCGGTATCCGGCATGCTGAAGATCCTCG
CCCGGTGA

Upstream 100 bases:

>100_bases
CGCGGCGTCGCCAAGCGCTGACCGCCGCTTCCCGCGTTCTTTCCCGACTGTTCACCGCGCGTTGCCCGGCTGGGTTCCGG
TGCCCGCCACCATCGGCGGA

Downstream 100 bases:

>100_bases
CCCACGTTCTGCCAGGCGAAGGGCTCACCGCGGCCAGCTCGGAACGGAATCACCTCGGCGGTCTCCGGATCAGCTGCGAT
ACTCATGTGAAAGAGCGCCG

Product: putative glycosyltransferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRIVQLANFYGPRSGGLRTALHHLGAGYVAAGHEVVLIVPGPRRREEVLPGGAVRITLPALPIPWTGGYRAADPRRVADV
LTGLRPDVLEVSDRLTLRGFGRWARRRDVAGVMISHERLDRLLGQVLPGPLARRCADIANRHTAADYDIVVCTTEFARAE
FRRIGAPNVELVPLGVDLDLFSPRRRDGRLRADLAAPGHPLLVHCGRLSVEKRVDRSIEAVGELNRAGAPVRLVVAGDGP
RRDALEKRARSVPALPDGRPAVHFTGFISDRHRVATLLATADVSLAPGPHETFGLAALEALAAGTPVVASRSSALADIVT
ADCGAIADDDPAAFATAVTDILARPPATRRRAARHRAEQFTWGRAVSGMLKILAR

Sequences:

>Translated_375_residues
MRIVQLANFYGPRSGGLRTALHHLGAGYVAAGHEVVLIVPGPRRREEVLPGGAVRITLPALPIPWTGGYRAADPRRVADV
LTGLRPDVLEVSDRLTLRGFGRWARRRDVAGVMISHERLDRLLGQVLPGPLARRCADIANRHTAADYDIVVCTTEFARAE
FRRIGAPNVELVPLGVDLDLFSPRRRDGRLRADLAAPGHPLLVHCGRLSVEKRVDRSIEAVGELNRAGAPVRLVVAGDGP
RRDALEKRARSVPALPDGRPAVHFTGFISDRHRVATLLATADVSLAPGPHETFGLAALEALAAGTPVVASRSSALADIVT
ADCGAIADDDPAAFATAVTDILARPPATRRRAARHRAEQFTWGRAVSGMLKILAR
>Mature_375_residues
MRIVQLANFYGPRSGGLRTALHHLGAGYVAAGHEVVLIVPGPRRREEVLPGGAVRITLPALPIPWTGGYRAADPRRVADV
LTGLRPDVLEVSDRLTLRGFGRWARRRDVAGVMISHERLDRLLGQVLPGPLARRCADIANRHTAADYDIVVCTTEFARAE
FRRIGAPNVELVPLGVDLDLFSPRRRDGRLRADLAAPGHPLLVHCGRLSVEKRVDRSIEAVGELNRAGAPVRLVVAGDGP
RRDALEKRARSVPALPDGRPAVHFTGFISDRHRVATLLATADVSLAPGPHETFGLAALEALAAGTPVVASRSSALADIVT
ADCGAIADDDPAAFATAVTDILARPPATRRRAARHRAEQFTWGRAVSGMLKILAR

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of the alpha-1,6-linked mannose residue of the triacyl phosphatidylinositol dimannoside (Ac3PIM2) to generate triacyl phosphatidylinositol trimannoside (Ac3PIM3) [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1788357, Length=266, Percent_Identity=27.0676691729323, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 40280; Mature: 40280

Theoretical pI: Translated: 11.29; Mature: 11.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVQLANFYGPRSGGLRTALHHLGAGYVAAGHEVVLIVPGPRRREEVLPGGAVRITLPA
CCEEEEHHHCCCCCCCHHHHHHHCCCCEEECCCEEEEEECCCCCHHHCCCCCEEEEEECC
LPIPWTGGYRAADPRRVADVLTGLRPDVLEVSDRLTLRGFGRWARRRDVAGVMISHERLD
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCHHHHEECHHHHH
RLLGQVLPGPLARRCADIANRHTAADYDIVVCTTEFARAEFRRIGAPNVELVPLGVDLDL
HHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCCCCCEEEEEEECCCCC
FSPRRRDGRLRADLAAPGHPLLVHCGRLSVEKRVDRSIEAVGELNRAGAPVRLVVAGDGP
CCCCCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
RRDALEKRARSVPALPDGRPAVHFTGFISDRHRVATLLATADVSLAPGPHETFGLAALEA
CHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHEECCCEECCCCCHHHHHHHHHH
LAAGTPVVASRSSALADIVTADCGAIADDDPAAFATAVTDILARPPATRRRAARHRAEQF
HHCCCCCEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TWGRAVSGMLKILAR
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIVQLANFYGPRSGGLRTALHHLGAGYVAAGHEVVLIVPGPRRREEVLPGGAVRITLPA
CCEEEEHHHCCCCCCCHHHHHHHCCCCEEECCCEEEEEECCCCCHHHCCCCCEEEEEECC
LPIPWTGGYRAADPRRVADVLTGLRPDVLEVSDRLTLRGFGRWARRRDVAGVMISHERLD
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCHHHHEECHHHHH
RLLGQVLPGPLARRCADIANRHTAADYDIVVCTTEFARAEFRRIGAPNVELVPLGVDLDL
HHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCCCCCEEEEEEECCCCC
FSPRRRDGRLRADLAAPGHPLLVHCGRLSVEKRVDRSIEAVGELNRAGAPVRLVVAGDGP
CCCCCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
RRDALEKRARSVPALPDGRPAVHFTGFISDRHRVATLLATADVSLAPGPHETFGLAALEA
CHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHEECCCEECCCCCHHHHHHHHHH
LAAGTPVVASRSSALADIVTADCGAIADDDPAAFATAVTDILARPPATRRRAARHRAEQF
HHCCCCCEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TWGRAVSGMLKILAR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10531227 [H]