Click here to switch to the map view.

The map label for this gene is mtrB [H]

Identifier: 54026583

GI number: 54026583

Start: 4797754

End: 4799619

Strand: Reverse

Name: mtrB [H]

Synonym: nfa46100

Alternate gene names: 54026583

Gene position: 4799619-4797754 (Counterclockwise)

Preceding gene: 54026584

Following gene: 54026582

Centisome position: 79.71

GC content: 71.6

Gene sequence:

>1866_bases
GTGACCGATGGGGATGCGGAGCGTCCCGTCGGCGAGCAGGGCAGCGCGGCCTCCCGCGCCGCCGAGCCGAGCGGGACGAT
TCCCCGTCTGGAGCGGTCGCTGGCGCCCGTCGGTGTCTGGTTCAAGGATCTGGGCACCGCGCTGGGGCACCTGTGGCGCC
GTTCGCTGCAACTGCGCGTCATCGTCTCGACGCTGACGCTTTCGCTGATCGTCATCACGATCCTCGGGGTGGTGCTGACG
AGCCAGATCACCGACCGGCTGCTGGACGCCAAGATCAACGCCGCGGTCGAGGAGATGGGCCGGGCGCGCAACACGGTGGA
GAGCCAGCTGGCCGGTGTGCACGACCTCGGCACCCAGCAGCAGCGGCTGGCCGACGCGCGCAGCGCGCTGTCCAATCGCG
GCGGCTCCGGCCGTTCCACGGGTGCCGCGGGCAGTTTCGATTCCGCGCTGAGCATGGTCGGCGGCACGCCGCAGCAGCAG
ATCGCCACCGGGCCGATCCAGGAGGTGCCCGAGGAACTGCGCCGGTTCGTGCAGCGCAATCAGGTCAGCTACCAGTTCGC
CACGGTCGCCGACCCGGACGGCTATCACGGGCGCGCGCTCATCATCGGCAGCCCGAGCGCGGAGATCCCGACCCTGGAGA
TCTACCTCGTCTTCCCGCTGGTCAACGAGGAGCGCAGCCTGGCGCTGATGCGGGGCACGATGATGATCGGCGGGCTGGTC
CTGCTCGTGCTGCTGGCGGCGATCACCGCGCTGGTCACCCGGCAGGTGGTGCTGCCCATCCGGTCGGCGGCGCGGATCGC
CAGCCGCTTCGCCGACGGCCGCCTCAAGGAACGCATGCTGGTGCGCGGTGAGGACGACATGGCGCGGCTGGCGCAGGCGT
TCAACGAGATGGCCGAGAGCCTGTCGAACCAGATCACCCAGCTCGAGGAATTCGGCAACCTGCAACGCCGGTTCACCTCC
GACGTCAGCCACGAACTGCGGACGCCGTTGACCACGGTGCGCATGGCCGCCGACCTGATCCACGGCTCCAGCGAGGACCT
CGATCCGGCGCTGGCGCGCAGCGCGGAACTGCTGGTGACCGAGCTGGACCGGTTCGAAGGGCTGCTCAACGACCTGCTCG
AGATCAGCCGCCACGACGCGGGCGTGGCCGAGTTGCAGGTGGAGTCGCTGGACGTGCGGATGTGCGCGCGGGCCGCCATC
TCCACGGTGCGGCATCTGGCCAAGGAGGCCGGCGTGGAGGTCGTCATCGACCTGCCGGAGGAGCCGCTGGTCGCCGAGGT
CGATCCGCGCCGTGTCGAACGCGTGCTGCGCAATCTGCTCGCCAACGCCATCGACCACAGCGAAGGCAAGCCGGTCCTGA
TCCGGATGCGCGGGGACAGCGAGGCCAACGCGGTCGCGTTCGTGGTGCGCGACCAGGGCGTGGGGCTGCGTCCGGGCGAG
GAGAAGCTGGTCTTCAACCGGTTCTGGCGCTCGGACCCCTCCCGCATGCGCCGCTCCGGCGGCACCGGTCTCGGCCTGTC
GATCAGTGTGGAGGACGCGAACCTGCACGACGGCAGGCTGGAGGCGTGGGGCGAGCCGGGTGTCGGGGCCAGCTTCCGGT
TGACGTTGCCGCTGGTGCGCGGACGCAAGATGGGACCGAGCCCGCTGCCGCTGGAGCCCGCGGTGCGCAAGGCCGTGCCG
CCGCGCCCGGCCGAACCCGAGGCCGTGGACGGCGACGCCCCCACGATGCCGGTGCCGCGCACCGAGCCGGGGCCCGCCGC
CGACGGAGCGGGCTCCGCCGCCGTGTCCGGAGCGCCCGCGGCCGAGCCGGATTCCGGCGGCACCGGCGGCGCGGTGCTCA
CCGAACCGGGAGACGAACAGTCATGA

Upstream 100 bases:

>100_bases
ACGTGCACGTGCAGCGGCTGCGCGCGAAGGTGGAGAAGGACCCGGAGAATCCTGAGATCGTGCTGACCGTTCGGGGGGTC
GGCTACAAGGCCGGACCGCC

Downstream 100 bases:

>100_bases
CGATGCGTGCTGCCAGGTTGTCCGGATCCACCGGCCTCACCGCGGCGCTGGTCGCGGTGCTGCTGGTGCTCACCGGGTGC
GCGAGCCTGCCCGAGTCGTC

Product: putative two-component system sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MTDGDAERPVGEQGSAASRAAEPSGTIPRLERSLAPVGVWFKDLGTALGHLWRRSLQLRVIVSTLTLSLIVITILGVVLT
SQITDRLLDAKINAAVEEMGRARNTVESQLAGVHDLGTQQQRLADARSALSNRGGSGRSTGAAGSFDSALSMVGGTPQQQ
IATGPIQEVPEELRRFVQRNQVSYQFATVADPDGYHGRALIIGSPSAEIPTLEIYLVFPLVNEERSLALMRGTMMIGGLV
LLVLLAAITALVTRQVVLPIRSAARIASRFADGRLKERMLVRGEDDMARLAQAFNEMAESLSNQITQLEEFGNLQRRFTS
DVSHELRTPLTTVRMAADLIHGSSEDLDPALARSAELLVTELDRFEGLLNDLLEISRHDAGVAELQVESLDVRMCARAAI
STVRHLAKEAGVEVVIDLPEEPLVAEVDPRRVERVLRNLLANAIDHSEGKPVLIRMRGDSEANAVAFVVRDQGVGLRPGE
EKLVFNRFWRSDPSRMRRSGGTGLGLSISVEDANLHDGRLEAWGEPGVGASFRLTLPLVRGRKMGPSPLPLEPAVRKAVP
PRPAEPEAVDGDAPTMPVPRTEPGPAADGAGSAAVSGAPAAEPDSGGTGGAVLTEPGDEQS

Sequences:

>Translated_621_residues
MTDGDAERPVGEQGSAASRAAEPSGTIPRLERSLAPVGVWFKDLGTALGHLWRRSLQLRVIVSTLTLSLIVITILGVVLT
SQITDRLLDAKINAAVEEMGRARNTVESQLAGVHDLGTQQQRLADARSALSNRGGSGRSTGAAGSFDSALSMVGGTPQQQ
IATGPIQEVPEELRRFVQRNQVSYQFATVADPDGYHGRALIIGSPSAEIPTLEIYLVFPLVNEERSLALMRGTMMIGGLV
LLVLLAAITALVTRQVVLPIRSAARIASRFADGRLKERMLVRGEDDMARLAQAFNEMAESLSNQITQLEEFGNLQRRFTS
DVSHELRTPLTTVRMAADLIHGSSEDLDPALARSAELLVTELDRFEGLLNDLLEISRHDAGVAELQVESLDVRMCARAAI
STVRHLAKEAGVEVVIDLPEEPLVAEVDPRRVERVLRNLLANAIDHSEGKPVLIRMRGDSEANAVAFVVRDQGVGLRPGE
EKLVFNRFWRSDPSRMRRSGGTGLGLSISVEDANLHDGRLEAWGEPGVGASFRLTLPLVRGRKMGPSPLPLEPAVRKAVP
PRPAEPEAVDGDAPTMPVPRTEPGPAADGAGSAAVSGAPAAEPDSGGTGGAVLTEPGDEQS
>Mature_620_residues
TDGDAERPVGEQGSAASRAAEPSGTIPRLERSLAPVGVWFKDLGTALGHLWRRSLQLRVIVSTLTLSLIVITILGVVLTS
QITDRLLDAKINAAVEEMGRARNTVESQLAGVHDLGTQQQRLADARSALSNRGGSGRSTGAAGSFDSALSMVGGTPQQQI
ATGPIQEVPEELRRFVQRNQVSYQFATVADPDGYHGRALIIGSPSAEIPTLEIYLVFPLVNEERSLALMRGTMMIGGLVL
LVLLAAITALVTRQVVLPIRSAARIASRFADGRLKERMLVRGEDDMARLAQAFNEMAESLSNQITQLEEFGNLQRRFTSD
VSHELRTPLTTVRMAADLIHGSSEDLDPALARSAELLVTELDRFEGLLNDLLEISRHDAGVAELQVESLDVRMCARAAIS
TVRHLAKEAGVEVVIDLPEEPLVAEVDPRRVERVLRNLLANAIDHSEGKPVLIRMRGDSEANAVAFVVRDQGVGLRPGEE
KLVFNRFWRSDPSRMRRSGGTGLGLSISVEDANLHDGRLEAWGEPGVGASFRLTLPLVRGRKMGPSPLPLEPAVRKAVPP
RPAEPEAVDGDAPTMPVPRTEPGPAADGAGSAAVSGAPAAEPDSGGTGGAVLTEPGDEQS

Specific function: Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=283, Percent_Identity=29.3286219081272, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788393, Length=287, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=30.0847457627119, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1787894, Length=274, Percent_Identity=29.9270072992701, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081816, Length=441, Percent_Identity=27.2108843537415, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=28.5140562248996, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786783, Length=336, Percent_Identity=25.5952380952381, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789149, Length=329, Percent_Identity=25.531914893617, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=27.9661016949153, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786912, Length=218, Percent_Identity=31.651376146789, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1789403, Length=344, Percent_Identity=27.6162790697674, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=29.9559471365639, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=311, Percent_Identity=25.4019292604502, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1789808, Length=267, Percent_Identity=29.5880149812734, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788279, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI48994928, Length=227, Percent_Identity=26.431718061674, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=24.5689655172414, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=28.2051282051282, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790551, Length=229, Percent_Identity=27.9475982532751, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI1790861, Length=282, Percent_Identity=29.4326241134752, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66431; Mature: 66300

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGDAERPVGEQGSAASRAAEPSGTIPRLERSLAPVGVWFKDLGTALGHLWRRSLQLRV
CCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVSTLTLSLIVITILGVVLTSQITDRLLDAKINAAVEEMGRARNTVESQLAGVHDLGTQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHH
QRLADARSALSNRGGSGRSTGAAGSFDSALSMVGGTPQQQIATGPIQEVPEELRRFVQRN
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHC
QVSYQFATVADPDGYHGRALIIGSPSAEIPTLEIYLVFPLVNEERSLALMRGTMMIGGLV
CCCEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHH
LLVLLAAITALVTRQVVLPIRSAARIASRFADGRLKERMLVRGEDDMARLAQAFNEMAES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSNQITQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADLIHGSSEDLDPALARSAELLVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ELDRFEGLLNDLLEISRHDAGVAELQVESLDVRMCARAAISTVRHLAKEAGVEVVIDLPE
HHHHHHHHHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
EPLVAEVDPRRVERVLRNLLANAIDHSEGKPVLIRMRGDSEANAVAFVVRDQGVGLRPGE
CCCEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCC
EKLVFNRFWRSDPSRMRRSGGTGLGLSISVEDANLHDGRLEAWGEPGVGASFRLTLPLVR
HHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEHHC
GRKMGPSPLPLEPAVRKAVPPRPAEPEAVDGDAPTMPVPRTEPGPAADGAGSAAVSGAPA
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AEPDSGGTGGAVLTEPGDEQS
CCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TDGDAERPVGEQGSAASRAAEPSGTIPRLERSLAPVGVWFKDLGTALGHLWRRSLQLRV
CCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVSTLTLSLIVITILGVVLTSQITDRLLDAKINAAVEEMGRARNTVESQLAGVHDLGTQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHH
QRLADARSALSNRGGSGRSTGAAGSFDSALSMVGGTPQQQIATGPIQEVPEELRRFVQRN
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHC
QVSYQFATVADPDGYHGRALIIGSPSAEIPTLEIYLVFPLVNEERSLALMRGTMMIGGLV
CCCEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHH
LLVLLAAITALVTRQVVLPIRSAARIASRFADGRLKERMLVRGEDDMARLAQAFNEMAES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSNQITQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADLIHGSSEDLDPALARSAELLVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ELDRFEGLLNDLLEISRHDAGVAELQVESLDVRMCARAAISTVRHLAKEAGVEVVIDLPE
HHHHHHHHHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
EPLVAEVDPRRVERVLRNLLANAIDHSEGKPVLIRMRGDSEANAVAFVVRDQGVGLRPGE
CCCEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCC
EKLVFNRFWRSDPSRMRRSGGTGLGLSISVEDANLHDGRLEAWGEPGVGASFRLTLPLVR
HHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEHHC
GRKMGPSPLPLEPAVRKAVPPRPAEPEAVDGDAPTMPVPRTEPGPAADGAGSAAVSGAPA
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AEPDSGGTGGAVLTEPGDEQS
CCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA