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The map label for this gene is thiL [H]

Identifier: 54026172

GI number: 54026172

Start: 4350653

End: 4351654

Strand: Reverse

Name: thiL [H]

Synonym: nfa42010

Alternate gene names: 54026172

Gene position: 4351654-4350653 (Counterclockwise)

Preceding gene: 54026176

Following gene: 54026171

Centisome position: 72.27

GC content: 75.65

Gene sequence:

>1002_bases
GTGATCGGCGAGGACGGGACGCCGCCGACGGTGCGCGAGCTCGGGGAGTTCGCGCTCATCGAGCGGATCAACGCCGGTCG
TCGGCAGGGCCCGCAGGTGCTGCTCGGCCCGGGCGACGACGCGGCGGTGGTGGCGGCGCCGGACGGGCGGTTCGCGGTGA
GCACCGACATGCTCGTCGAGGGCAGGCATTTCCGGCTGGACTGGTCGACACCGCACGACGTCGGCCGCAAGGCCATCGCC
CAGAACGCCGCCGACGTGTTCGCGATGGGCGCGCGGCCGACCGCCTTCGTGGTCGCCCTCGGCTGTCCCGCCGACACCCC
GGTCGAGGTGATCGACGGACTCGCGGCGGGCATGTGGGCCGAGGCGGAGCGGGTGGGCGCGTCCGTCGCGGGCGGTGACC
TCGTGCGCAGCCGCGAGGTGGTCGTCTCGATCACGGCCTTCGGCGACCTGGGCGGACTGCCGCCGATCACCCGGGCCGGT
GCGCGGCCGGGCCACGTGGTCGCGGTCGCGGGCCGGCTCGGCTGGTCGGCGGCCGGCTTGGCGGTGCTGACCACCGGTGC
GGCGCCGGACGGTCCGGGGGCCGAAGCGGTGGCGCTGCATCGGGTTCCGCACCCGCCGTACGAGGCGGCGCCGGTGGGTG
GCGGCCCGCGCCCGCACGCGTTGACCGACGTCTCCGACGGCCTGCTGGCCGACCTCGGCCACATCGCCGACGCCTCCGGT
GTGGCGATCGACCTGTCCGCGTCCGCGTTGCGCGACGACGCACTGACCGCACTCGCCGCCACGATGAATGTCGATGCGCG
GCAATGGGTTCTGGGTGGCGGCGAGGATCACGCCTTCGTCGGCGCCTGGGCGCGGGAGGCACCGCTGCCGCCGGGCTGGC
GGGCGATCGGGACGGTCCGCGCGGGGTCGGGGGTCACCGTGGACGGGATGAGCTGGGACGGCGCCGTGGGCTGGGAATCG
TTCCGTGGGGCGGAGGCTGCGCCGGGAAACGAACCGCGATAG

Upstream 100 bases:

>100_bases
TGCCCCGGGTCCTTTCCTCGTCCGCCTCGATGGTCTCGGTCGGGATCAGGGTACCGTCGAGCGGATTTCTGCCTGCACGA
CCGTCGCGGAAGGAGGACCG

Downstream 100 bases:

>100_bases
GTTGTGCGGTCATGGGCGCGAAACCACTGTCGGAAATCATGGATCCGGGCTGGGCGCAGGCGCTGGAGCCGGTGGCCGAC
CGCATCAGGGCGATGGGTGA

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIGEDGTPPTVRELGEFALIERINAGRRQGPQVLLGPGDDAAVVAAPDGRFAVSTDMLVEGRHFRLDWSTPHDVGRKAIA
QNAADVFAMGARPTAFVVALGCPADTPVEVIDGLAAGMWAEAERVGASVAGGDLVRSREVVVSITAFGDLGGLPPITRAG
ARPGHVVAVAGRLGWSAAGLAVLTTGAAPDGPGAEAVALHRVPHPPYEAAPVGGGPRPHALTDVSDGLLADLGHIADASG
VAIDLSASALRDDALTALAATMNVDARQWVLGGGEDHAFVGAWAREAPLPPGWRAIGTVRAGSGVTVDGMSWDGAVGWES
FRGAEAAPGNEPR

Sequences:

>Translated_333_residues
MIGEDGTPPTVRELGEFALIERINAGRRQGPQVLLGPGDDAAVVAAPDGRFAVSTDMLVEGRHFRLDWSTPHDVGRKAIA
QNAADVFAMGARPTAFVVALGCPADTPVEVIDGLAAGMWAEAERVGASVAGGDLVRSREVVVSITAFGDLGGLPPITRAG
ARPGHVVAVAGRLGWSAAGLAVLTTGAAPDGPGAEAVALHRVPHPPYEAAPVGGGPRPHALTDVSDGLLADLGHIADASG
VAIDLSASALRDDALTALAATMNVDARQWVLGGGEDHAFVGAWAREAPLPPGWRAIGTVRAGSGVTVDGMSWDGAVGWES
FRGAEAAPGNEPR
>Mature_333_residues
MIGEDGTPPTVRELGEFALIERINAGRRQGPQVLLGPGDDAAVVAAPDGRFAVSTDMLVEGRHFRLDWSTPHDVGRKAIA
QNAADVFAMGARPTAFVVALGCPADTPVEVIDGLAAGMWAEAERVGASVAGGDLVRSREVVVSITAFGDLGGLPPITRAG
ARPGHVVAVAGRLGWSAAGLAVLTTGAAPDGPGAEAVALHRVPHPPYEAAPVGGGPRPHALTDVSDGLLADLGHIADASG
VAIDLSASALRDDALTALAATMNVDARQWVLGGGEDHAFVGAWAREAPLPPGWRAIGTVRAGSGVTVDGMSWDGAVGWES
FRGAEAAPGNEPR

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=275, Percent_Identity=33.8181818181818, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33792; Mature: 33792

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGEDGTPPTVRELGEFALIERINAGRRQGPQVLLGPGDDAAVVAAPDGRFAVSTDMLVE
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCEEEECCEEEC
GRHFRLDWSTPHDVGRKAIAQNAADVFAMGARPTAFVVALGCPADTPVEVIDGLAAGMWA
CCEEEEECCCCHHHHHHHHHHCCHHEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
EAERVGASVAGGDLVRSREVVVSITAFGDLGGLPPITRAGARPGHVVAVAGRLGWSAAGL
HHHHHCCCCCCCHHEECCEEEEEEEEECCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCE
AVLTTGAAPDGPGAEAVALHRVPHPPYEAAPVGGGPRPHALTDVSDGLLADLGHIADASG
EEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCCCC
VAIDLSASALRDDALTALAATMNVDARQWVLGGGEDHAFVGAWAREAPLPPGWRAIGTVR
EEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHHHCCCCCCCCEEEEEEE
AGSGVTVDGMSWDGAVGWESFRGAEAAPGNEPR
CCCCCEEECCCCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIGEDGTPPTVRELGEFALIERINAGRRQGPQVLLGPGDDAAVVAAPDGRFAVSTDMLVE
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCEEEECCEEEC
GRHFRLDWSTPHDVGRKAIAQNAADVFAMGARPTAFVVALGCPADTPVEVIDGLAAGMWA
CCEEEEECCCCHHHHHHHHHHCCHHEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
EAERVGASVAGGDLVRSREVVVSITAFGDLGGLPPITRAGARPGHVVAVAGRLGWSAAGL
HHHHHCCCCCCCHHEECCEEEEEEEEECCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCE
AVLTTGAAPDGPGAEAVALHRVPHPPYEAAPVGGGPRPHALTDVSDGLLADLGHIADASG
EEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCCCC
VAIDLSASALRDDALTALAATMNVDARQWVLGGGEDHAFVGAWAREAPLPPGWRAIGTVR
EEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHHHCCCCCCCCEEEEEEE
AGSGVTVDGMSWDGAVGWESFRGAEAAPGNEPR
CCCCCEEECCCCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]