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The map label for this gene is pamO [H]

Identifier: 54026068

GI number: 54026068

Start: 4248430

End: 4250040

Strand: Reverse

Name: pamO [H]

Synonym: nfa40970

Alternate gene names: 54026068

Gene position: 4250040-4248430 (Counterclockwise)

Preceding gene: 54026069

Following gene: 54026067

Centisome position: 70.58

GC content: 68.22

Gene sequence:

>1611_bases
GTGAGCACCGAATTCGATGCCGTGGTGGTCGGAGCCGGGATCTCGGGCCTGTACGCGGTGTACAAACTGCGGCAGCGCGG
GATGCGGGTGCGGGGCTTCGAGTCCGCCGAGGGGCTGGGTGGCACCTGGTATCACAACCGGTATCCGGGCGCCCGGTGCG
ATGTGGAGAGCATCGACTACTCGTATTCGTTCGACGAGGAGTTGCAGCAGGAGTGGACCTGGTCGGAGCGGTTCGCGACG
CAGGAAGAGATCCTGCGGTATCTCGAGCACGTCGCCGACCGGCACGATCTGCGCTCGGCCTACGAGTTCTCGACCCGGGT
GACCGCGGCGGTCTTCGACGAACAGACGGCGCGGTGGACGGTCTCCACCGACACCGGCCGAACGGTGACGGCCCGCTACT
GCGTGCTCGCCACGGGTGTGTTGTCGGCGACGAACAAACCCGACATCCCCGGCCGGGACAGTTTCGGCGGGGAGCTGTAC
CACACCGGTGAGTGGCCGCACGAGCCGGTGCGTTTCGCCGGCAAGCGCGTGGGCGTGATCGGCACCGGATCGTCGGGGAT
CCAGGCGATTCCGGTGATCGCCGAGGAGGCCGCGCAGGTGGTGGTGTTCCAGCGCAGCCCGAACTATTCGATCCCGGCGG
GCAACCGGCGGTTGGATCCGGAGTTCGTGGCCGAGGTGAAGGCCAATTACGCGGAGCGGCGGCGGCTGTCGCGGATCAGC
GGGGGCGGCACGCCGAACAGTCCGTATCCCAAGGGTGCGCTCGAGGTCGACGAGGCCGAGCGCAGGCGGATCTACGACCA
GTGGTGGCAGCGGGGCGGCTACCTGTTCGCCAAGGCGTTCCCGGACCAGACGACGAACCCGGCGGCGAACGACACCGCGC
GCGAGTACGTCGAGGCCAAGATCCGGGAGATGGTGGCCGACCCGGAGATCGCCGAGCAGTTGATCCCGACCGACCATCCG
ATCGGCACCAAGCGGATCGTCACCGACACCGGCTATTTCCAGACCTACAACCGCGACAACGTCACCCTGGTGAACCTGCG
GCGGACTCCGATCGAGGAGATCACCGCGACCGGTGTGCGCACCAGCGGCGGGTCCTACGAGTTGGACATGCTGATCTTCG
CGACCGGGTTCGACGCGATGACCGGCTCGCTGCTGCGGATCGACATCCGCGGCCGCGGCGGGCGGGAGTTGCGGCAGGAA
TGGGCGGCAGGCCCGCGCACCTACCTGGGCCTGGCGGTGGCGGGCTTCCCGAACATGTTCATCCTGGCCGGGCCGGGCAG
CCCCAGCGTGCTGGCGAACATGGTGCTGGTGGCCGAGCAGCACGTGGACTGGATCGCGCGCTGCCTGGATCATCTCGACG
AGCACAACGTGACCACCATCGAGGCCGGTGCCGAGGCGGTGGACCAGTGGGTGGCCGAGTGCAACACCAAGGCCGCGGCC
ACGTTGTTCCCGCAGGCCAACTCCTGGTATCTGGGCGCCAACATCCCCGGGAAGCCGCGGGTGTTCATGCCCTACATCGG
CGGGTTCGGCAACTACAGCCAGATCTGCGACGAGGTGGCCGCCGCCGGGTACAAGGGCTTCGTCCTCGACGGCGCCGCGG
CGGACGAGTGA

Upstream 100 bases:

>100_bases
CCGACAGCTACTGGGGCCACGAGTGGATGTGGATGCGGGAGATGAAGCAGGCGCAGCAGGAGGCCGCCGCGCAGACCGCC
GAGCCGCGGGAAGTGGCGTC

Downstream 100 bases:

>100_bases
GGGGTGACCGAGATGGGCGCACAGCGACGGTCCGATCTGCACCCCGACGTGGCGGCGATGCTCGCGGCACTGGAGTCGTT
CCCGGATGTCACCCGCTACG

Product: putative monooxygenase

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MSTEFDAVVVGAGISGLYAVYKLRQRGMRVRGFESAEGLGGTWYHNRYPGARCDVESIDYSYSFDEELQQEWTWSERFAT
QEEILRYLEHVADRHDLRSAYEFSTRVTAAVFDEQTARWTVSTDTGRTVTARYCVLATGVLSATNKPDIPGRDSFGGELY
HTGEWPHEPVRFAGKRVGVIGTGSSGIQAIPVIAEEAAQVVVFQRSPNYSIPAGNRRLDPEFVAEVKANYAERRRLSRIS
GGGTPNSPYPKGALEVDEAERRRIYDQWWQRGGYLFAKAFPDQTTNPAANDTAREYVEAKIREMVADPEIAEQLIPTDHP
IGTKRIVTDTGYFQTYNRDNVTLVNLRRTPIEEITATGVRTSGGSYELDMLIFATGFDAMTGSLLRIDIRGRGGRELRQE
WAAGPRTYLGLAVAGFPNMFILAGPGSPSVLANMVLVAEQHVDWIARCLDHLDEHNVTTIEAGAEAVDQWVAECNTKAAA
TLFPQANSWYLGANIPGKPRVFMPYIGGFGNYSQICDEVAAAGYKGFVLDGAAADE

Sequences:

>Translated_536_residues
MSTEFDAVVVGAGISGLYAVYKLRQRGMRVRGFESAEGLGGTWYHNRYPGARCDVESIDYSYSFDEELQQEWTWSERFAT
QEEILRYLEHVADRHDLRSAYEFSTRVTAAVFDEQTARWTVSTDTGRTVTARYCVLATGVLSATNKPDIPGRDSFGGELY
HTGEWPHEPVRFAGKRVGVIGTGSSGIQAIPVIAEEAAQVVVFQRSPNYSIPAGNRRLDPEFVAEVKANYAERRRLSRIS
GGGTPNSPYPKGALEVDEAERRRIYDQWWQRGGYLFAKAFPDQTTNPAANDTAREYVEAKIREMVADPEIAEQLIPTDHP
IGTKRIVTDTGYFQTYNRDNVTLVNLRRTPIEEITATGVRTSGGSYELDMLIFATGFDAMTGSLLRIDIRGRGGRELRQE
WAAGPRTYLGLAVAGFPNMFILAGPGSPSVLANMVLVAEQHVDWIARCLDHLDEHNVTTIEAGAEAVDQWVAECNTKAAA
TLFPQANSWYLGANIPGKPRVFMPYIGGFGNYSQICDEVAAAGYKGFVLDGAAADE
>Mature_535_residues
STEFDAVVVGAGISGLYAVYKLRQRGMRVRGFESAEGLGGTWYHNRYPGARCDVESIDYSYSFDEELQQEWTWSERFATQ
EEILRYLEHVADRHDLRSAYEFSTRVTAAVFDEQTARWTVSTDTGRTVTARYCVLATGVLSATNKPDIPGRDSFGGELYH
TGEWPHEPVRFAGKRVGVIGTGSSGIQAIPVIAEEAAQVVVFQRSPNYSIPAGNRRLDPEFVAEVKANYAERRRLSRISG
GGTPNSPYPKGALEVDEAERRRIYDQWWQRGGYLFAKAFPDQTTNPAANDTAREYVEAKIREMVADPEIAEQLIPTDHPI
GTKRIVTDTGYFQTYNRDNVTLVNLRRTPIEEITATGVRTSGGSYELDMLIFATGFDAMTGSLLRIDIRGRGGRELRQEW
AAGPRTYLGLAVAGFPNMFILAGPGSPSVLANMVLVAEQHVDWIARCLDHLDEHNVTTIEAGAEAVDQWVAECNTKAAAT
LFPQANSWYLGANIPGKPRVFMPYIGGFGNYSQICDEVAAAGYKGFVLDGAAADE

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=210, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 59266; Mature: 59135

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEFDAVVVGAGISGLYAVYKLRQRGMRVRGFESAEGLGGTWYHNRYPGARCDVESIDY
CCCCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCC
SYSFDEELQQEWTWSERFATQEEILRYLEHVADRHDLRSAYEFSTRVTAAVFDEQTARWT
CCCCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEE
VSTDTGRTVTARYCVLATGVLSATNKPDIPGRDSFGGELYHTGEWPHEPVRFAGKRVGVI
EECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCHHHHHCCCEEEEE
GTGSSGIQAIPVIAEEAAQVVVFQRSPNYSIPAGNRRLDPEFVAEVKANYAERRRLSRIS
ECCCCCCEEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GGGTPNSPYPKGALEVDEAERRRIYDQWWQRGGYLFAKAFPDQTTNPAANDTAREYVEAK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
IREMVADPEIAEQLIPTDHPIGTKRIVTDTGYFQTYNRDNVTLVNLRRTPIEEITATGVR
HHHHHCCHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCEEEEEECCCCHHHHHHCCEE
TSGGSYELDMLIFATGFDAMTGSLLRIDIRGRGGRELRQEWAAGPRTYLGLAVAGFPNMF
CCCCCEEEEEEEEEECCHHHCCCEEEEEECCCCCHHHHHHHCCCCCHHEEEEEECCCCEE
ILAGPGSPSVLANMVLVAEQHVDWIARCLDHLDEHNVTTIEAGAEAVDQWVAECNTKAAA
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCEE
TLFPQANSWYLGANIPGKPRVFMPYIGGFGNYSQICDEVAAAGYKGFVLDGAAADE
EECCCCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure 
STEFDAVVVGAGISGLYAVYKLRQRGMRVRGFESAEGLGGTWYHNRYPGARCDVESIDY
CCCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCC
SYSFDEELQQEWTWSERFATQEEILRYLEHVADRHDLRSAYEFSTRVTAAVFDEQTARWT
CCCCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEE
VSTDTGRTVTARYCVLATGVLSATNKPDIPGRDSFGGELYHTGEWPHEPVRFAGKRVGVI
EECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCHHHHHCCCEEEEE
GTGSSGIQAIPVIAEEAAQVVVFQRSPNYSIPAGNRRLDPEFVAEVKANYAERRRLSRIS
ECCCCCCEEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GGGTPNSPYPKGALEVDEAERRRIYDQWWQRGGYLFAKAFPDQTTNPAANDTAREYVEAK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
IREMVADPEIAEQLIPTDHPIGTKRIVTDTGYFQTYNRDNVTLVNLRRTPIEEITATGVR
HHHHHCCHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCEEEEEECCCCHHHHHHCCEE
TSGGSYELDMLIFATGFDAMTGSLLRIDIRGRGGRELRQEWAAGPRTYLGLAVAGFPNMF
CCCCCEEEEEEEEEECCHHHCCCEEEEEECCCCCHHHHHHHCCCCCHHEEEEEECCCCEE
ILAGPGSPSVLANMVLVAEQHVDWIARCLDHLDEHNVTTIEAGAEAVDQWVAECNTKAAA
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCEE
TLFPQANSWYLGANIPGKPRVFMPYIGGFGNYSQICDEVAAAGYKGFVLDGAAADE
EECCCCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA