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The map label for this gene is yfhM [H]

Identifier: 54025551

GI number: 54025551

Start: 3792270

End: 3793247

Strand: Reverse

Name: yfhM [H]

Synonym: nfa35810

Alternate gene names: 54025551

Gene position: 3793247-3792270 (Counterclockwise)

Preceding gene: 54025554

Following gene: 54025550

Centisome position: 63.0

GC content: 71.47

Gene sequence:

>978_bases
GTGACGGTGACCGAGCGGCCCACGTCCCGGATCGTGACCAACGACGGCATTCGCATGCACGTCACCGAGCGCGGCGCGGG
GCAGCCGGTGATCTTCTGCCACGGCTTCCCGCACACCGGGTTCATCTGGCACCGCCAGCTCGACGCCCTGGCCGCGGCCG
GCTACCACGCGCTGGCACCGGATCTGCGCGGCTACGGCCGCACGGACGCACCGGCCGACCCCGAGGCGTACACCAATCGC
GCGGTGATCGGTGATCTGCTGGCCCTGCTCGACGATCTCGCCGCGGAGCGGGCGGTGTTCGTCGGCCTCGACTTCGGTGC
CGTGCTGGTGTGGGAGCTGGCCCAACGGGCACCCGAGCGGGTGCGCGGGGTGATCGTGCTGAACAATCCCTACGCGCCGC
GGCCGTCCCGCGCGCCCTCGCAACTGTGGGCCAAGGCGGCGCAGCGGCACTTCCTGCACCTGGACTACTTCCAGCGCCCC
GGTGTCGCGGACCGCGAACTCGCGGCCGCGCCACGCGATTTCCTCGCCCGGGTGTACTACGCGCTCAGCGGCGACTACCA
CTACCTCGACACCTGGCGCTTCCCGCCCGGCTCCGGCTACCTCGAGGTATTGCCGGACGCGCCCGCCCTGCCGTGGCCGT
GGCTGTCGGCGGCGGAGTTCGACGTGCTCGCCGCCGAATTCGAACGCACCGGCTTCTCCGGTGGGCTGGCCTGGTACCGC
AGCCTGGACCGCAACTGGGAGCTGGGTGCCGATCTCGACCCGACGGTCCGGGTGCCCGCGTATTTCGTCTACGGCGAAAA
GGACCCGGACATGGCCGGATTCAGCGGTCGCGATCCGCTGGGGGTGATGCGCGCGCACGTGCCCGACCTACGCGGTGTCA
CCGAGATCCCGGGCGCCGGGCATCTGCTGCCCCTCGAACGCGGTGCCGAGGTCGATCGCCTGGTGCTGGCCCACCTCACC
GACCTCGGGTTGGCGTGA

Upstream 100 bases:

>100_bases
CCGGTGACGACCGCGACCCGGTCGCGTAGGTCTGGTATTCCGCTCACGACTGTCGGACATTACCGTGAAACGTAGAACGT
GTTCTAACTTTGGAGGCGCA

Downstream 100 bases:

>100_bases
GCACGACCGCGCCGGTCCGGCTGACCGGACGCCAGTGGTGGCTGCTGGTCGTCTCCTGCCTGGGGGTGGCACTCGTCATC
GCGGCGATGGCCGGGCTCTA

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTVTERPTSRIVTNDGIRMHVTERGAGQPVIFCHGFPHTGFIWHRQLDALAAAGYHALAPDLRGYGRTDAPADPEAYTNR
AVIGDLLALLDDLAAERAVFVGLDFGAVLVWELAQRAPERVRGVIVLNNPYAPRPSRAPSQLWAKAAQRHFLHLDYFQRP
GVADRELAAAPRDFLARVYYALSGDYHYLDTWRFPPGSGYLEVLPDAPALPWPWLSAAEFDVLAAEFERTGFSGGLAWYR
SLDRNWELGADLDPTVRVPAYFVYGEKDPDMAGFSGRDPLGVMRAHVPDLRGVTEIPGAGHLLPLERGAEVDRLVLAHLT
DLGLA

Sequences:

>Translated_325_residues
MTVTERPTSRIVTNDGIRMHVTERGAGQPVIFCHGFPHTGFIWHRQLDALAAAGYHALAPDLRGYGRTDAPADPEAYTNR
AVIGDLLALLDDLAAERAVFVGLDFGAVLVWELAQRAPERVRGVIVLNNPYAPRPSRAPSQLWAKAAQRHFLHLDYFQRP
GVADRELAAAPRDFLARVYYALSGDYHYLDTWRFPPGSGYLEVLPDAPALPWPWLSAAEFDVLAAEFERTGFSGGLAWYR
SLDRNWELGADLDPTVRVPAYFVYGEKDPDMAGFSGRDPLGVMRAHVPDLRGVTEIPGAGHLLPLERGAEVDRLVLAHLT
DLGLA
>Mature_324_residues
TVTERPTSRIVTNDGIRMHVTERGAGQPVIFCHGFPHTGFIWHRQLDALAAAGYHALAPDLRGYGRTDAPADPEAYTNRA
VIGDLLALLDDLAAERAVFVGLDFGAVLVWELAQRAPERVRGVIVLNNPYAPRPSRAPSQLWAKAAQRHFLHLDYFQRPG
VADRELAAAPRDFLARVYYALSGDYHYLDTWRFPPGSGYLEVLPDAPALPWPWLSAAEFDVLAAEFERTGFSGGLAWYRS
LDRNWELGADLDPTVRVPAYFVYGEKDPDMAGFSGRDPLGVMRAHVPDLRGVTEIPGAGHLLPLERGAEVDRLVLAHLTD
LGLA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=311, Percent_Identity=33.4405144694534, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI218777840, Length=320, Percent_Identity=26.5625, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI13376164, Length=320, Percent_Identity=26.5625, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI218777837, Length=152, Percent_Identity=33.5526315789474, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI145611434, Length=132, Percent_Identity=34.0909090909091, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554012, Length=183, Percent_Identity=25.6830601092896, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324392, Length=121, Percent_Identity=32.2314049586777, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 35884; Mature: 35753

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTERPTSRIVTNDGIRMHVTERGAGQPVIFCHGFPHTGFIWHRQLDALAAAGYHALAP
CCCCCCCCCCEEECCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHCC
DLRGYGRTDAPADPEAYTNRAVIGDLLALLDDLAAERAVFVGLDFGAVLVWELAQRAPER
CHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCHHH
VRGVIVLNNPYAPRPSRAPSQLWAKAAQRHFLHLDYFQRPGVADRELAAAPRDFLARVYY
HEEEEEECCCCCCCCCCCHHHHHHHHHHHHEEEEHHHCCCCCCCHHHHCCCHHHHHHHHH
ALSGDYHYLDTWRFPPGSGYLEVLPDAPALPWPWLSAAEFDVLAAEFERTGFSGGLAWYR
HHCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
SLDRNWELGADLDPTVRVPAYFVYGEKDPDMAGFSGRDPLGVMRAHVPDLRGVTEIPGAG
HCCCCCCCCCCCCCCEECCEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
HLLPLERGAEVDRLVLAHLTDLGLA
CEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVTERPTSRIVTNDGIRMHVTERGAGQPVIFCHGFPHTGFIWHRQLDALAAAGYHALAP
CCCCCCCCCEEECCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHCC
DLRGYGRTDAPADPEAYTNRAVIGDLLALLDDLAAERAVFVGLDFGAVLVWELAQRAPER
CHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCHHH
VRGVIVLNNPYAPRPSRAPSQLWAKAAQRHFLHLDYFQRPGVADRELAAAPRDFLARVYY
HEEEEEECCCCCCCCCCCHHHHHHHHHHHHEEEEHHHCCCCCCCHHHHCCCHHHHHHHHH
ALSGDYHYLDTWRFPPGSGYLEVLPDAPALPWPWLSAAEFDVLAAEFERTGFSGGLAWYR
HHCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
SLDRNWELGADLDPTVRVPAYFVYGEKDPDMAGFSGRDPLGVMRAHVPDLRGVTEIPGAG
HCCCCCCCCCCCCCCEECCEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
HLLPLERGAEVDRLVLAHLTDLGLA
CEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]