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The map label for this gene is qacA [H]

Identifier: 54025550

GI number: 54025550

Start: 3790711

End: 3792273

Strand: Reverse

Name: qacA [H]

Synonym: nfa35800

Alternate gene names: 54025550

Gene position: 3792273-3790711 (Counterclockwise)

Preceding gene: 54025551

Following gene: 54025542

Centisome position: 62.98

GC content: 73.96

Gene sequence:

>1563_bases
GTGAGCACGACCGCGCCGGTCCGGCTGACCGGACGCCAGTGGTGGCTGCTGGTCGTCTCCTGCCTGGGGGTGGCACTCGT
CATCGCGGCGATGGCCGGGCTCTACACGGCGCTGCCGGAGATCGCGGCCGACACCGGCGCCAGCCAGCAGCAGCTGACCT
GGATCGTGGACGGCTACACGCTGACCCTGGCGTGCCTGGTGCTGCCGTGCGGCGCGCTGGGCGACCGCTACGGCCGCAGG
CTGGTGCTCGTGCTCGGGCTGGTGATCTTCGCGGCGTCCTCGGCGCTGCCGCTGCTCGTCGACAGTCCGCACTGGTTGAT
CGGGGCGCGCGCGCTCACCGGTGTGGGCGCGGCACTGGTGATGCCCGCCACGCTGTCGCTGCTCACCGCGAGCTTCCCCG
AGTCGCGGCGGTCGGTGGCGGTGGCCGTGTGGGCCGGCGTCGCGGGCGTGAGCGCGGTGATCGGCTTCCTCGGGTCGGGC
TTGCTGCTCGCGCACTTCTCCTGGGTGTCGATCTTCCTCGGCATGGCGATCGCGGCCGCGGTGCTCGCGGTCGCGGGATG
CACGGTCGGGGAGACCGTCGACGAGGATCGGCCCGGCCTCGATCCTGCCGGTGCGCTGAGTTCGGCCGCCGCGATCGGGC
TGCTGGTGGTGGGCGCGATCGAGGCGCCGGTACGGGGATGGACCGACCCGGTCGTCCTCGGGGTGCTGGCCGGGGCCGTG
GTCGCGGGCGTGCTGTTCGCGGTCGTCGAGCTGCGGTTGGCGACCCGCGGGGCACGGCCGCTGTTGGATGTGCGGCTGTT
CGCCGTGCGGGGATTCGGCAGCGGGACGGTGGCGGTGGGTGTGCAGTTCCTGGCCGCGTTCGGCACCTTCCTGCTGATCG
TGCAGTTCATGCAACTTTTCCTCGGCTACAGCCCGCTGATGTCGGCGGTGGCGTTGGCGCCGATGGTGGGACCGATGATC
GCCCTCGCCGCCGTCGCGCCGTGGCTGGCCGAGCGCTTCGGGCTGCGGCTGCCGACGGTGATCGGGGTGGGGCTGGTCGG
TGTCGGTTTGATCGGTCTCTCGCGGCTCACCGCCGACAGCGGCTACGTCGATCTGCTGTGGCCGCTGCTGGTGATGAGCA
GCGGGCTCGGGCTGAGTTCCCCGCCCGCGACCGCGGCGATCATCGCGAACACGCCTGTCGCCGACCACGGCGTCGCCTCC
GCGGTGAACGACGCCGCCCGCGAGGTGGGGGCGGCGTTGGGCATCGCCGTCGCGGGCAGTGTGCTGGCCGCGGGGTACAG
CGCCCGCATCGGTCCGGTGCTGCCGCAGTTGCCCGAGCCGGCGCGCGAGCCGGTGGGCAGTTCGCTGGCCGCGGCGCTCG
AGGTGGCCGACCGCGCCGGCCCGCAGGCGGCGCCGCTGGTCGATCTGGCACAGGCTGCATTCGTGCACGGGATGCAGAAC
GCGGCGCTGGCCCTGGGCGTGTCGAGCGTGGTGGCGGCCGTGGTCCTCGGGGCGTGGGCGCCGGGACGGGGTGCGCGGGG
ATCGGCCGAGGCCGGCGACGTGGCGGAGCAGGCGGTGCGCTGA

Upstream 100 bases:

>100_bases
GTGTCACCGAGATCCCGGGCGCCGGGCATCTGCTGCCCCTCGAACGCGGTGCCGAGGTCGATCGCCTGGTGCTGGCCCAC
CTCACCGACCTCGGGTTGGC

Downstream 100 bases:

>100_bases
GCGCGACACGGCTCGGAAACCGGCGGGGCGGCCCCGGGAAGCTTCCCGGGGCCGCCGCCGACCCAACCAGTCGGTGCCCG
ACCTGGCTCCAGACCCCGAC

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSTTAPVRLTGRQWWLLVVSCLGVALVIAAMAGLYTALPEIAADTGASQQQLTWIVDGYTLTLACLVLPCGALGDRYGRR
LVLVLGLVIFAASSALPLLVDSPHWLIGARALTGVGAALVMPATLSLLTASFPESRRSVAVAVWAGVAGVSAVIGFLGSG
LLLAHFSWVSIFLGMAIAAAVLAVAGCTVGETVDEDRPGLDPAGALSSAAAIGLLVVGAIEAPVRGWTDPVVLGVLAGAV
VAGVLFAVVELRLATRGARPLLDVRLFAVRGFGSGTVAVGVQFLAAFGTFLLIVQFMQLFLGYSPLMSAVALAPMVGPMI
ALAAVAPWLAERFGLRLPTVIGVGLVGVGLIGLSRLTADSGYVDLLWPLLVMSSGLGLSSPPATAAIIANTPVADHGVAS
AVNDAAREVGAALGIAVAGSVLAAGYSARIGPVLPQLPEPAREPVGSSLAAALEVADRAGPQAAPLVDLAQAAFVHGMQN
AALALGVSSVVAAVVLGAWAPGRGARGSAEAGDVAEQAVR

Sequences:

>Translated_520_residues
MSTTAPVRLTGRQWWLLVVSCLGVALVIAAMAGLYTALPEIAADTGASQQQLTWIVDGYTLTLACLVLPCGALGDRYGRR
LVLVLGLVIFAASSALPLLVDSPHWLIGARALTGVGAALVMPATLSLLTASFPESRRSVAVAVWAGVAGVSAVIGFLGSG
LLLAHFSWVSIFLGMAIAAAVLAVAGCTVGETVDEDRPGLDPAGALSSAAAIGLLVVGAIEAPVRGWTDPVVLGVLAGAV
VAGVLFAVVELRLATRGARPLLDVRLFAVRGFGSGTVAVGVQFLAAFGTFLLIVQFMQLFLGYSPLMSAVALAPMVGPMI
ALAAVAPWLAERFGLRLPTVIGVGLVGVGLIGLSRLTADSGYVDLLWPLLVMSSGLGLSSPPATAAIIANTPVADHGVAS
AVNDAAREVGAALGIAVAGSVLAAGYSARIGPVLPQLPEPAREPVGSSLAAALEVADRAGPQAAPLVDLAQAAFVHGMQN
AALALGVSSVVAAVVLGAWAPGRGARGSAEAGDVAEQAVR
>Mature_519_residues
STTAPVRLTGRQWWLLVVSCLGVALVIAAMAGLYTALPEIAADTGASQQQLTWIVDGYTLTLACLVLPCGALGDRYGRRL
VLVLGLVIFAASSALPLLVDSPHWLIGARALTGVGAALVMPATLSLLTASFPESRRSVAVAVWAGVAGVSAVIGFLGSGL
LLAHFSWVSIFLGMAIAAAVLAVAGCTVGETVDEDRPGLDPAGALSSAAAIGLLVVGAIEAPVRGWTDPVVLGVLAGAVV
AGVLFAVVELRLATRGARPLLDVRLFAVRGFGSGTVAVGVQFLAAFGTFLLIVQFMQLFLGYSPLMSAVALAPMVGPMIA
LAAVAPWLAERFGLRLPTVIGVGLVGVGLIGLSRLTADSGYVDLLWPLLVMSSGLGLSSPPATAAIIANTPVADHGVASA
VNDAAREVGAALGIAVAGSVLAAGYSARIGPVLPQLPEPAREPVGSSLAAALEVADRAGPQAAPLVDLAQAAFVHGMQNA
ALALGVSSVVAAVVLGAWAPGRGARGSAEAGDVAEQAVR

Specific function: Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=389, Percent_Identity=27.2493573264781, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788710, Length=324, Percent_Identity=23.7654320987654, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789042, Length=427, Percent_Identity=22.7166276346604, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790195, Length=398, Percent_Identity=26.8844221105528, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324954, Length=388, Percent_Identity=25.2577319587629, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52154; Mature: 52023

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTAPVRLTGRQWWLLVVSCLGVALVIAAMAGLYTALPEIAADTGASQQQLTWIVDGYT
CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
LTLACLVLPCGALGDRYGRRLVLVLGLVIFAASSALPLLVDSPHWLIGARALTGVGAALV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCHHHH
MPATLSLLTASFPESRRSVAVAVWAGVAGVSAVIGFLGSGLLLAHFSWVSIFLGMAIAAA
HHHHHHHHHHCCCHHHHHEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VLAVAGCTVGETVDEDRPGLDPAGALSSAAAIGLLVVGAIEAPVRGWTDPVVLGVLAGAV
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VAGVLFAVVELRLATRGARPLLDVRLFAVRGFGSGTVAVGVQFLAAFGTFLLIVQFMQLF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGYSPLMSAVALAPMVGPMIALAAVAPWLAERFGLRLPTVIGVGLVGVGLIGLSRLTADS
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
GYVDLLWPLLVMSSGLGLSSPPATAAIIANTPVADHGVASAVNDAAREVGAALGIAVAGS
CHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLAAGYSARIGPVLPQLPEPAREPVGSSLAAALEVADRAGPQAAPLVDLAQAAFVHGMQN
HHHCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AALALGVSSVVAAVVLGAWAPGRGARGSAEAGDVAEQAVR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
STTAPVRLTGRQWWLLVVSCLGVALVIAAMAGLYTALPEIAADTGASQQQLTWIVDGYT
CCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
LTLACLVLPCGALGDRYGRRLVLVLGLVIFAASSALPLLVDSPHWLIGARALTGVGAALV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCHHHH
MPATLSLLTASFPESRRSVAVAVWAGVAGVSAVIGFLGSGLLLAHFSWVSIFLGMAIAAA
HHHHHHHHHHCCCHHHHHEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VLAVAGCTVGETVDEDRPGLDPAGALSSAAAIGLLVVGAIEAPVRGWTDPVVLGVLAGAV
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VAGVLFAVVELRLATRGARPLLDVRLFAVRGFGSGTVAVGVQFLAAFGTFLLIVQFMQLF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGYSPLMSAVALAPMVGPMIALAAVAPWLAERFGLRLPTVIGVGLVGVGLIGLSRLTADS
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
GYVDLLWPLLVMSSGLGLSSPPATAAIIANTPVADHGVASAVNDAAREVGAALGIAVAGS
CHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLAAGYSARIGPVLPQLPEPAREPVGSSLAAALEVADRAGPQAAPLVDLAQAAFVHGMQN
HHHCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AALALGVSSVVAAVVLGAWAPGRGARGSAEAGDVAEQAVR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]