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The map label for this gene is glmS3

Identifier: 53723027

GI number: 53723027

Start: 2714171

End: 2715988

Strand: Reverse

Name: glmS3

Synonym: BPSS2009

Alternate gene names: 53723027

Gene position: 2715988-2714171 (Counterclockwise)

Preceding gene: 53723028

Following gene: 53723026

Centisome position: 85.6

GC content: 67.66

Gene sequence:

>1818_bases
ATGTGCGGGATCGTCGGCGCGGTAGCGCAACGGAACATCGTTCCGATTCTGATCGAAGGCTTACGCCGCCTCGAATATCG
CGGCTACGATTCGTGCGGCGTGGCGACCGTGGTGGACGGCGAGGCGCGGCGCGAGCGCAGCGTCTCGCGCGTCGCCGATC
TCGAGGCGCACGTGCGTACGGCGGGCCTCGCCGGCACCACGGGCATCGCGCACACGCGCTGGGCGACGCACGGCGCGCCC
GCCACGTGCAACGCGCACCCGATCTTCTCGCGCGATCACATCGCACTCGTTCACAACGGCATCATCGAGAATCACGAAGC
GCTGCGCACGCAGCTCGCCGGCGAGCATTACGAATTCGACGGGCAGACCGATACCGAAGTCGTCGCGCATCTGATTCACA
GCAAGTACCGCGGCGATCTGCTGGCGGCCGTTCGCGATGCGACGGCGCAGTTGCGCGGCGCGTATGCGATCGCGGTGTTC
AGCAAGACCGAGCCGAACCGGCTGATCGGCGCGCGGGTCGGCTCGCCGCTCGTCGTCGGCCTGAAGGACGGCGAGTGCTT
CCTGGCGTCGGACGCGCTCGCGCTCGCGGGCATTACCGATCAGTTCATCTTTCTCGACGAAGGCGACATCGTCGAGCTGA
CGCCGCGCGGCGCGCGGATCGTCGATCGCGACGGCAGGCCGGTCGTGCGCGCGGTGCAGACGGTATCGGCGGCGCAGGGC
GCGGCGGAGCTCGGCGAATACCGGCATTTCATGCAGAAGGAGATCTTCGAGCAGCCGCGCGCGGTGGCGGCGACGATCCC
CGACGCGGGGCTGTTCGATCCGGCGGTGTTCGGCCACGACGCGCGGCGCGCGTTCGAGCAGATCGACAACGTGCTGATCC
TCGCGTGCGGGACGAGCCATTACGCGGGGCTGACCGCGCGCCGCTGGCTCGAGACGGTCGCGCGGATTCCCGCGCAGGTC
GAGATCGCGAGCGAATACCGGTACAGCGACGCGGTGGCGATGCCGAACACGCTGATCGTCGTGATATCGCAATCGGGCGA
GACGGCCGACACGCTCGCCGCGCTGAAGTATGCGCAGGCGCTCGGCCATATCGATACGCTCGCGATCTGCAACGTGCCGA
CGAGCGCGATGATGCGGCAAGCCGGGCTGCGCTTCCTGACGCGCGCGGGCTCGGAAATCGGCGTCGCGTCGACGAAGGCG
TTTACGACGCAACTCGTCGCGCTGTTCGTGCTGGCGGTCACGCTCGGGCGGATGCGCGGCTACGTGGACGACGCGCAACT
CGCGCGCTGCACGCAGCAGTTGCGCCGGCTGCCCGGCGCGCTCGAGGACGTGCTCGCGCTCGAGCCGCGGGTGAAGCGTT
GGGCGGACGAGTTCGCGTGCCACGAGAACGCGCTGTTCCTCGGGCGCGGACTGCACTATCCGATCGCGCTCGAAGGCGCG
CTGAAGCTCAAGGAGATCTCGTACATTCACGCGGAAGCGTATCCGGCGGGCGAGCTGAAGCACGGCCCGCTCGCGCTCGT
GACGAATACGATGCCGGTCGCGACGATCGCGCCGAACGACGCGTTGCTCGAGAAGCTGAAGTCGAACATGCAGGAAGTGC
GCGCGCGCGGCGGGCAGCTCTATGTGTTCGCCGATGCGGACACGCGGATCGACGACGGCGACGGGATATCGGTGATGAGG
ATGCCGGATTATTACGGACTGCTGTCGCCGATTCTGCATGTCGTGCCGCTGCAACTGCTTGCGTATCACGCGGCGTGCAA
CAGGGGGACGGATATCGACAAGCCGAGGAATCTGGCGAAGTCGGTGACGGTGGAGTAG

Upstream 100 bases:

>100_bases
CGCGCCCGCGCGCTGCGGGCTCGCCACCGCGTCGGCCGATTTCGCGCCGCGCGACGCAAGCGCGCGCGCGGGCATCGCGA
GCCTTTGGAGGTAACGAGTC

Downstream 100 bases:

>100_bases
GGGAGGTGGGGCGCGGTTGTGTTTGATGATTTGCATTAATTCCGGTTACGGGGCCTAGATTCATCTTTGGCTACTAGCGC
TCGCACCTGCCGCTGAGCCT

Product: glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 3

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MCGIVGAVAQRNIVPILIEGLRRLEYRGYDSCGVATVVDGEARRERSVSRVADLEAHVRTAGLAGTTGIAHTRWATHGAP
ATCNAHPIFSRDHIALVHNGIIENHEALRTQLAGEHYEFDGQTDTEVVAHLIHSKYRGDLLAAVRDATAQLRGAYAIAVF
SKTEPNRLIGARVGSPLVVGLKDGECFLASDALALAGITDQFIFLDEGDIVELTPRGARIVDRDGRPVVRAVQTVSAAQG
AAELGEYRHFMQKEIFEQPRAVAATIPDAGLFDPAVFGHDARRAFEQIDNVLILACGTSHYAGLTARRWLETVARIPAQV
EIASEYRYSDAVAMPNTLIVVISQSGETADTLAALKYAQALGHIDTLAICNVPTSAMMRQAGLRFLTRAGSEIGVASTKA
FTTQLVALFVLAVTLGRMRGYVDDAQLARCTQQLRRLPGALEDVLALEPRVKRWADEFACHENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTNTMPVATIAPNDALLEKLKSNMQEVRARGGQLYVFADADTRIDDGDGISVMR
MPDYYGLLSPILHVVPLQLLAYHAACNRGTDIDKPRNLAKSVTVE

Sequences:

>Translated_605_residues
MCGIVGAVAQRNIVPILIEGLRRLEYRGYDSCGVATVVDGEARRERSVSRVADLEAHVRTAGLAGTTGIAHTRWATHGAP
ATCNAHPIFSRDHIALVHNGIIENHEALRTQLAGEHYEFDGQTDTEVVAHLIHSKYRGDLLAAVRDATAQLRGAYAIAVF
SKTEPNRLIGARVGSPLVVGLKDGECFLASDALALAGITDQFIFLDEGDIVELTPRGARIVDRDGRPVVRAVQTVSAAQG
AAELGEYRHFMQKEIFEQPRAVAATIPDAGLFDPAVFGHDARRAFEQIDNVLILACGTSHYAGLTARRWLETVARIPAQV
EIASEYRYSDAVAMPNTLIVVISQSGETADTLAALKYAQALGHIDTLAICNVPTSAMMRQAGLRFLTRAGSEIGVASTKA
FTTQLVALFVLAVTLGRMRGYVDDAQLARCTQQLRRLPGALEDVLALEPRVKRWADEFACHENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTNTMPVATIAPNDALLEKLKSNMQEVRARGGQLYVFADADTRIDDGDGISVMR
MPDYYGLLSPILHVVPLQLLAYHAACNRGTDIDKPRNLAKSVTVE
>Mature_605_residues
MCGIVGAVAQRNIVPILIEGLRRLEYRGYDSCGVATVVDGEARRERSVSRVADLEAHVRTAGLAGTTGIAHTRWATHGAP
ATCNAHPIFSRDHIALVHNGIIENHEALRTQLAGEHYEFDGQTDTEVVAHLIHSKYRGDLLAAVRDATAQLRGAYAIAVF
SKTEPNRLIGARVGSPLVVGLKDGECFLASDALALAGITDQFIFLDEGDIVELTPRGARIVDRDGRPVVRAVQTVSAAQG
AAELGEYRHFMQKEIFEQPRAVAATIPDAGLFDPAVFGHDARRAFEQIDNVLILACGTSHYAGLTARRWLETVARIPAQV
EIASEYRYSDAVAMPNTLIVVISQSGETADTLAALKYAQALGHIDTLAICNVPTSAMMRQAGLRFLTRAGSEIGVASTKA
FTTQLVALFVLAVTLGRMRGYVDDAQLARCTQQLRRLPGALEDVLALEPRVKRWADEFACHENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTNTMPVATIAPNDALLEKLKSNMQEVRARGGQLYVFADADTRIDDGDGISVMR
MPDYYGLLSPILHVVPLQLLAYHAACNRGTDIDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=683, Percent_Identity=35.4319180087848, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI4826742, Length=692, Percent_Identity=34.393063583815, Blast_Score=361, Evalue=1e-99,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=52.8641571194763, Blast_Score=627, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=228, Percent_Identity=27.6315789473684, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539970, Length=716, Percent_Identity=34.2178770949721, Blast_Score=355, Evalue=6e-98,
Organism=Caenorhabditis elegans, GI17532899, Length=434, Percent_Identity=36.6359447004608, Blast_Score=252, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17532897, Length=434, Percent_Identity=36.6359447004608, Blast_Score=252, Evalue=5e-67,
Organism=Saccharomyces cerevisiae, GI6322745, Length=445, Percent_Identity=36.1797752808989, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6323731, Length=437, Percent_Identity=29.5194508009153, Blast_Score=183, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6323730, Length=206, Percent_Identity=33.0097087378641, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323958, Length=281, Percent_Identity=28.1138790035587, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21357745, Length=688, Percent_Identity=34.593023255814, Blast_Score=360, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65556; Mature: 65556

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPILIEGLRRLEYRGYDSCGVATVVDGEARRERSVSRVADLEAHVRT
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
AGLAGTTGIAHTRWATHGAPATCNAHPIFSRDHIALVHNGIIENHEALRTQLAGEHYEFD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEECC
GQTDTEVVAHLIHSKYRGDLLAAVRDATAQLRGAYAIAVFSKTEPNRLIGARVGSPLVVG
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEECCCCCEEEE
LKDGECFLASDALALAGITDQFIFLDEGDIVELTPRGARIVDRDGRPVVRAVQTVSAAQG
ECCCCEEEECCCHHEECCCCEEEEECCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHH
AAELGEYRHFMQKEIFEQPRAVAATIPDAGLFDPAVFGHDARRAFEQIDNVLILACGTSH
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCHHHHHHHHHHCCEEEEEECCCC
YAGLTARRWLETVARIPAQVEIASEYRYSDAVAMPNTLIVVISQSGETADTLAALKYAQA
CCCHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
LGHIDTLAICNVPTSAMMRQAGLRFLTRAGSEIGVASTKAFTTQLVALFVLAVTLGRMRG
HCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
YVDDAQLARCTQQLRRLPGALEDVLALEPRVKRWADEFACHENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTNTMPVATIAPNDALLEKLKSNMQEVRARGGQL
EEHHHHHEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTRIDDGDGISVMRMPDYYGLLSPILHVVPLQLLAYHAACNRGTDIDKPRNLAK
EEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SVTVE
HCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPILIEGLRRLEYRGYDSCGVATVVDGEARRERSVSRVADLEAHVRT
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
AGLAGTTGIAHTRWATHGAPATCNAHPIFSRDHIALVHNGIIENHEALRTQLAGEHYEFD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEECC
GQTDTEVVAHLIHSKYRGDLLAAVRDATAQLRGAYAIAVFSKTEPNRLIGARVGSPLVVG
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEECCCCCEEEE
LKDGECFLASDALALAGITDQFIFLDEGDIVELTPRGARIVDRDGRPVVRAVQTVSAAQG
ECCCCEEEECCCHHEECCCCEEEEECCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHH
AAELGEYRHFMQKEIFEQPRAVAATIPDAGLFDPAVFGHDARRAFEQIDNVLILACGTSH
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCHHHHHHHHHHCCEEEEEECCCC
YAGLTARRWLETVARIPAQVEIASEYRYSDAVAMPNTLIVVISQSGETADTLAALKYAQA
CCCHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
LGHIDTLAICNVPTSAMMRQAGLRFLTRAGSEIGVASTKAFTTQLVALFVLAVTLGRMRG
HCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
YVDDAQLARCTQQLRRLPGALEDVLALEPRVKRWADEFACHENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTNTMPVATIAPNDALLEKLKSNMQEVRARGGQL
EEHHHHHEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTRIDDGDGISVMRMPDYYGLLSPILHVVPLQLLAYHAACNRGTDIDKPRNLAK
EEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SVTVE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]