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The map label for this gene is mprA

Identifier: 53723014

GI number: 53723014

Start: 2695482

End: 2696984

Strand: Reverse

Name: mprA

Synonym: BPSS1993

Alternate gene names: NA

Gene position: 2696984-2695482 (Counterclockwise)

Preceding gene: 53723018

Following gene: 53723013

Centisome position: 85.0

GC content: 70.26

Gene sequence:

>1503_bases
ATGTCAATATTGATTCGTACTGCTTCGTTCAAGGCGACCGTCCTGTGTGCCGCGCTGGCCGGCCTCGTTTCGGCCGCGCA
AGCGGAAACCGCGGCCGCGCCCCAGGTGCCGGGGCCCGCCGACGCGGTCAATCAGTTGATCGTCAAGTTGCGCGCGGTGA
AGACGCCGCCCGGTGCGACGGCCGCGAAGGCCGAGCGCGCGGACGTTCAGGCCGTCATCGATCGCGTGCTCGCCGCGCGC
AATGCGCGGGCGGCGGGGCGTGCGTTCGGCGCGGCCGCCGCATCCGCGCCCGGCAATCCGGACGACCCCGCCGCGGGCAT
TCGCATCAAGCGCGACATGTCGGGCGGCGCGACCGTGCTGTCGCTGCAGCGCCACGTGTCGCTCGCGCAGGCCGAGGCGC
TCGCGCGCGACTTCGCGGCGGACGGCGCGATCGAATATGCGGAGCCCGATGCGCGGATGCATCCGTTCGTCGTGCCGAAC
GATACGCGCTATTCGGAGCAATGGGGCTACTTCAATCCGACCGCCGGCGCGAATCTGCCGAAGGCTTGGGATCGCACGAC
CGGCTCCGCGCGCGTCGTCGTCGCCGTCATCGATACCGGCTACCGTCCGCATGCGGATCTCGCCGCGAACCTGCTGCCGG
GCTACGACTTCATCTCCGATATCCCGAGCGCGAACGACGGCAATGGCCGCGACAGCGACGCATCGGATCCCGGCGACTGG
GTGAGCGCGCAGGAAGACGGCGATCCGAGCGGCCCATTCTATGGCTGCGGCGCGAGCGACAGCTCATGGCACGGCACGCA
CGTCGCGGGCACGATCGGCGCGGTGACGAACAACGGCGTCGGCGTGGCGGGCATCTCGTGGGTCGGCAAGGTGCTGCCCG
TGCGCGTGCTCGGCAAGTGCGGCGGGATGCTGAGCGACATCGCCGACGGCATGCGCTGGGCGGCGGGCCTGCCGGTGCCG
GGCGCGCCGTCGAATCCGAACCCGGCGAAGGTGCTGAACCTGAGCCTCGGCGGATACGGCCGCACATGCAGCTCGACGTA
CCAGAACGCGATCAACGAAATCACGTCGCGCGGCGCGAACGTCGTTGTCGCCGCGGGCAATAACGGCGGCTCGGTGTCGA
CGACTCAGCCGGCGAATTGCCGGGGCGTGATCGCGGTCGGCGCGATCGACAGCCGCGGCGTGCGCGCGAGCTTCAGCAAC
ACCGGCGCCGCGGTGAAGATCTCCGCGCCGGGCGTCGGCATTCTGTCGACGCTCAATGCGGGCAAGACCTCGCCGGGCGC
GGACAGCTACGCGAGCTATAGCGGCACGAGCATGGCAACGCCGCATGTCGCGGGCACGGTCGCGCTGATGCTCGCCGTCA
ACTCGACGCTGTCGCCTTCGCAGATCTTGCAGCGGCTGCAATCGAGCGCGCGGCCGTTCTCGAGCGGATCGAGCTGCTCG
ACGAGCACGTGCGGCGCAGGGCTGCTCGACGCAGGCAACGCGGTCGACGCCGCCGCGCAGTGA

Upstream 100 bases:

>100_bases
GCGCGGCGTGTCCTTTCTTGCCGGCAGCGCAGCGAAGCAAGCAGCGACAGCACAACATCGTCGACTCATTCCGTTCAATT
TCGTTTGGGGGAGTATGAGC

Downstream 100 bases:

>100_bases
GCGAAATCGGGCGTTGCGGCCGAAAGGCCGCGCGTTCGCGCGCGCCGATGCCCGTCAGCGGGATGCGGGCATCGGCGCGG
CGAATCGACGTGCGGCGCGC

Product: serine metalloprotease precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MSILIRTASFKATVLCAALAGLVSAAQAETAAAPQVPGPADAVNQLIVKLRAVKTPPGATAAKAERADVQAVIDRVLAAR
NARAAGRAFGAAAASAPGNPDDPAAGIRIKRDMSGGATVLSLQRHVSLAQAEALARDFAADGAIEYAEPDARMHPFVVPN
DTRYSEQWGYFNPTAGANLPKAWDRTTGSARVVVAVIDTGYRPHADLAANLLPGYDFISDIPSANDGNGRDSDASDPGDW
VSAQEDGDPSGPFYGCGASDSSWHGTHVAGTIGAVTNNGVGVAGISWVGKVLPVRVLGKCGGMLSDIADGMRWAAGLPVP
GAPSNPNPAKVLNLSLGGYGRTCSSTYQNAINEITSRGANVVVAAGNNGGSVSTTQPANCRGVIAVGAIDSRGVRASFSN
TGAAVKISAPGVGILSTLNAGKTSPGADSYASYSGTSMATPHVAGTVALMLAVNSTLSPSQILQRLQSSARPFSSGSSCS
TSTCGAGLLDAGNAVDAAAQ

Sequences:

>Translated_500_residues
MSILIRTASFKATVLCAALAGLVSAAQAETAAAPQVPGPADAVNQLIVKLRAVKTPPGATAAKAERADVQAVIDRVLAAR
NARAAGRAFGAAAASAPGNPDDPAAGIRIKRDMSGGATVLSLQRHVSLAQAEALARDFAADGAIEYAEPDARMHPFVVPN
DTRYSEQWGYFNPTAGANLPKAWDRTTGSARVVVAVIDTGYRPHADLAANLLPGYDFISDIPSANDGNGRDSDASDPGDW
VSAQEDGDPSGPFYGCGASDSSWHGTHVAGTIGAVTNNGVGVAGISWVGKVLPVRVLGKCGGMLSDIADGMRWAAGLPVP
GAPSNPNPAKVLNLSLGGYGRTCSSTYQNAINEITSRGANVVVAAGNNGGSVSTTQPANCRGVIAVGAIDSRGVRASFSN
TGAAVKISAPGVGILSTLNAGKTSPGADSYASYSGTSMATPHVAGTVALMLAVNSTLSPSQILQRLQSSARPFSSGSSCS
TSTCGAGLLDAGNAVDAAAQ
>Mature_499_residues
SILIRTASFKATVLCAALAGLVSAAQAETAAAPQVPGPADAVNQLIVKLRAVKTPPGATAAKAERADVQAVIDRVLAARN
ARAAGRAFGAAAASAPGNPDDPAAGIRIKRDMSGGATVLSLQRHVSLAQAEALARDFAADGAIEYAEPDARMHPFVVPND
TRYSEQWGYFNPTAGANLPKAWDRTTGSARVVVAVIDTGYRPHADLAANLLPGYDFISDIPSANDGNGRDSDASDPGDWV
SAQEDGDPSGPFYGCGASDSSWHGTHVAGTIGAVTNNGVGVAGISWVGKVLPVRVLGKCGGMLSDIADGMRWAAGLPVPG
APSNPNPAKVLNLSLGGYGRTCSSTYQNAINEITSRGANVVVAAGNNGGSVSTTQPANCRGVIAVGAIDSRGVRASFSNT
GAAVKISAPGVGILSTLNAGKTSPGADSYASYSGTSMATPHVAGTVALMLAVNSTLSPSQILQRLQSSARPFSSGSSCST
STCGAGLLDAGNAVDAAAQ

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=222, Percent_Identity=34.6846846846847, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324576, Length=221, Percent_Identity=32.579185520362, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319893, Length=216, Percent_Identity=35.6481481481481, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 50235; Mature: 50104

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIRTASFKATVLCAALAGLVSAAQAETAAAPQVPGPADAVNQLIVKLRAVKTPPGAT
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
AAKAERADVQAVIDRVLAARNARAAGRAFGAAAASAPGNPDDPAAGIRIKRDMSGGATVL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEE
SLQRHVSLAQAEALARDFAADGAIEYAEPDARMHPFVVPNDTRYSEQWGYFNPTAGANLP
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCC
KAWDRTTGSARVVVAVIDTGYRPHADLAANLLPGYDFISDIPSANDGNGRDSDASDPGDW
CHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCC
VSAQEDGDPSGPFYGCGASDSSWHGTHVAGTIGAVTNNGVGVAGISWVGKVLPVRVLGKC
CCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECEECCCCCEEHHHHHHHHHHHHHHHHH
GGMLSDIADGMRWAAGLPVPGAPSNPNPAKVLNLSLGGYGRTCSSTYQNAINEITSRGAN
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCE
VVVAAGNNGGSVSTTQPANCRGVIAVGAIDSRGVRASFSNTGAAVKISAPGVGILSTLNA
EEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCEEEECCCCCCHHHHCCC
GKTSPGADSYASYSGTSMATPHVAGTVALMLAVNSTLSPSQILQRLQSSARPFSSGSSCS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCC
TSTCGAGLLDAGNAVDAAAQ
CCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
SILIRTASFKATVLCAALAGLVSAAQAETAAAPQVPGPADAVNQLIVKLRAVKTPPGAT
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
AAKAERADVQAVIDRVLAARNARAAGRAFGAAAASAPGNPDDPAAGIRIKRDMSGGATVL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEE
SLQRHVSLAQAEALARDFAADGAIEYAEPDARMHPFVVPNDTRYSEQWGYFNPTAGANLP
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCC
KAWDRTTGSARVVVAVIDTGYRPHADLAANLLPGYDFISDIPSANDGNGRDSDASDPGDW
CHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCC
VSAQEDGDPSGPFYGCGASDSSWHGTHVAGTIGAVTNNGVGVAGISWVGKVLPVRVLGKC
CCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECEECCCCCEEHHHHHHHHHHHHHHHHH
GGMLSDIADGMRWAAGLPVPGAPSNPNPAKVLNLSLGGYGRTCSSTYQNAINEITSRGAN
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCE
VVVAAGNNGGSVSTTQPANCRGVIAVGAIDSRGVRASFSNTGAAVKISAPGVGILSTLNA
EEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCEEEECCCCCCHHHHCCC
GKTSPGADSYASYSGTSMATPHVAGTVALMLAVNSTLSPSQILQRLQSSARPFSSGSSCS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCC
TSTCGAGLLDAGNAVDAAAQ
CCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]