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The map label for this gene is pheA [H]

Identifier: 52842739

GI number: 52842739

Start: 2863336

End: 2863920

Strand: Direct

Name: pheA [H]

Synonym: lpg2531

Alternate gene names: 52842739

Gene position: 2863336-2863920 (Clockwise)

Preceding gene: 52842738

Following gene: 52842740

Centisome position: 84.27

GC content: 38.46

Gene sequence:

>585_bases
ATGAAGAATCTCGTTGAAGAAAAAGAAGCCTTTCGCTTCGGTGTTTCTGGAGATATCGGATCATTTTCTGAGGAAGCGGC
TTTGCTTTATGCCAGGAAAAAAGGCCTTAATGCCCATCTCGTTCATTTGCTGGATATGGAAGGCGTTTTAAATGCTATTG
AGAATGAAACTATAGATTTGGGCATCTTACCCGTTGTTAACCTTTTAGGAGGATTGGTAAAACCAGCATTTCAGGCTATG
GGCAAATATTCATTTACTCCCATCGATGAGATTTGGCATGACATAAACCAATGCCTGCTAGTTAAGACAAATACTCAAAA
TCATAAAATCACACATATTGTGTCACATCCTCAAGGCTTTGCCCAATGCAAAAAATTCCTAAGAAACAAATTTAAGAATG
CGAAAAAAATAGAATGGATCGATACAGCAAAAGCAGCAAAGGATTTGGCAGAAGGAATATTGCCACCCCATGCCGCAGTC
ATTGCATCGGCACGTTGTGCACCACTTTATGATTTGAAAATCAGTGCGAGAAATATTCAGGACAGTCATCTGAACAGAAC
AGCTTTTATATTAGTTAAAAAATAA

Upstream 100 bases:

>100_bases
CCGATAACATTGATTTAAGCGGGTTATCCGTTACCGATCCTTGCCTCAGTTGGGAGAAGACAGAATCGTTCCTGTTGGAA
CTGGCAGAGAGGGAAGCGTT

Downstream 100 bases:

>100_bases
GTGATAAGGTCTCTATCCGCTAAGGAGTTCATCATGAGTACGATTGAAGAACTAAGAAAACAAATTGAACAAACTGATGC
ATACATCATTGAAAAGTTGG

Product: chorismate mutase/prephenate dehydratase (P-protein)

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKNLVEEKEAFRFGVSGDIGSFSEEAALLYARKKGLNAHLVHLLDMEGVLNAIENETIDLGILPVVNLLGGLVKPAFQAM
GKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGFAQCKKFLRNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAV
IASARCAPLYDLKISARNIQDSHLNRTAFILVKK

Sequences:

>Translated_194_residues
MKNLVEEKEAFRFGVSGDIGSFSEEAALLYARKKGLNAHLVHLLDMEGVLNAIENETIDLGILPVVNLLGGLVKPAFQAM
GKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGFAQCKKFLRNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAV
IASARCAPLYDLKISARNIQDSHLNRTAFILVKK
>Mature_194_residues
MKNLVEEKEAFRFGVSGDIGSFSEEAALLYARKKGLNAHLVHLLDMEGVLNAIENETIDLGILPVVNLLGGLVKPAFQAM
GKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGFAQCKKFLRNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAV
IASARCAPLYDLKISARNIQDSHLNRTAFILVKK

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=188, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 21566; Mature: 21566

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLVEEKEAFRFGVSGDIGSFSEEAALLYARKKGLNAHLVHLLDMEGVLNAIENETIDL
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEE
GILPVVNLLGGLVKPAFQAMGKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGF
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEEECCCCCEEEEEECCCCHH
AQCKKFLRNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAVIASARCAPLYDLKISARNIQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECCCCC
DSHLNRTAFILVKK
HHHCCCEEEEEEEC
>Mature Secondary Structure
MKNLVEEKEAFRFGVSGDIGSFSEEAALLYARKKGLNAHLVHLLDMEGVLNAIENETIDL
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEE
GILPVVNLLGGLVKPAFQAMGKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGF
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEEECCCCCEEEEEECCCCHH
AQCKKFLRNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAVIASARCAPLYDLKISARNIQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECCCCC
DSHLNRTAFILVKK
HHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512561; 1444388 [H]