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The map label for this gene is aspB [H]

Identifier: 52842740

GI number: 52842740

Start: 2864214

End: 2865380

Strand: Direct

Name: aspB [H]

Synonym: lpg2532

Alternate gene names: 52842740

Gene position: 2864214-2865380 (Clockwise)

Preceding gene: 52842739

Following gene: 52842741

Centisome position: 84.3

GC content: 43.62

Gene sequence:

>1167_bases
ATGAACCATTATGAAAAAATGAGCTTGCTAAAAGATTCCGCAACAGTTGCCATCAATTCTCTAGCCCAACAAAAAATAAA
CGCGGGAATCAAAATTCATAATCTCAGTGCTGGAGAACCCAAACTGCCACCCCATCCCTCCATAATAAATGCCGTCACAC
AAGCTATGGAACAAGGACATACCCTTTATCCTCCAATAATGGGAATTCCTGAACTACGTCATATGGGCTGTGAATGGATG
TATAGATCCTATGATTGCTCATTCCAAAATGAGCAATGCCTGGTTGTGAATGGTGGAAAACTTGGCATTTATTTACTCAT
GCAATTATTACTGCAGCCTAACGACGAAGTCATTATTCCTTCTCCCTACTGGGTTTCCTATCCAGCCATGGTTAGCCTGT
TTGGCGGCACCCCCGTGCCAGTTGAAACGACAGAAGCCGAAGAATGGAAACTAACGCCACAGGCACTGCAAAAAGCGTGT
ACCACAAAAAGTAAAATACTCATTCTGAATAATGCCACCAATCCCACCGGAGCTCTGTATACCCAGTCCGAGCTGATTCA
CTTATTGCAAACTGCCAAGAAGCATAATCTTTTAGTGATCTCTGATGAAGTTTACAGCGAACTAACCTATGATGGGCATC
ATTACGTATCCTGTGGTTCTTTACCCCAGTTTCGAGAGCGTGTCATCATCATTCAAAGCTGTTCAAAAAACTTTTCCATG
ACCGGGTGGCGAGTGGGTTTTATTTTTGCCCCGGAAATATTCATCAAACCTTTAAGCGCCCTGGTCAGTCAAAGCACCAG
TGGAGTAACCACCCTTAGCCAATGGGCCGCTGTGGCTGCGCTGCAAGAAGTAAATCAAGTCAATATCTGGGTTCAGCAAA
ACATGGAAAAAAGAAGAAATTGCCTCCTCCGCACCTTGCATGACTATCTGGGATTGACCATAACACCTCCAATTTCCTCA
CTTTATGTTTTTCTTTCCCTAAAGGATATTGGCTGCAAAAATCAAAATTCCGAGGAGTTTTGTAAACAAGCTTTGGATAA
GGCAAATGTTGCGATGGTACCGGGAATCGCCTTTGGTAAAGAGGGTTACGTCCGCTTGTCTTTTGGAGGCAATGAAGACG
ATTTAAAATCAGGTATTTATGCTCTGGCGCAATGGCTGCATCGCTAA

Upstream 100 bases:

>100_bases
AATATTATGACTTTTTATCCAGGCAATATCACTTGCAGCAGGATTTCGTGAATCAATTATTCAAGATAATTATCTCAAAC
TCAAAAAAGGTCCAAAAATA

Downstream 100 bases:

>100_bases
TTAAAGTAATTCATTACTTTGCAAGAAGCATGACCAGACCTCTTACATAACTAGTCTCTTTTATTTTAAACGTTTCTGTG
GTGCCTCATTTAACGACTCT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHMGCEWM
YRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRTLHDYLGLTITPPISS
LYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR

Sequences:

>Translated_388_residues
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHMGCEWM
YRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRTLHDYLGLTITPPISS
LYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR
>Mature_388_residues
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHMGCEWM
YRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRTLHDYLGLTITPPISS
LYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=28.5359801488834, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=28.5359801488834, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=29.3729372937294, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI56713256, Length=395, Percent_Identity=27.0886075949367, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI56713254, Length=395, Percent_Identity=26.8354430379747, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI4507369, Length=366, Percent_Identity=21.0382513661202, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI149944424, Length=361, Percent_Identity=26.0387811634349, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI187936925, Length=324, Percent_Identity=25.6172839506173, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI14211921, Length=324, Percent_Identity=25.6172839506173, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788722, Length=375, Percent_Identity=28.2666666666667, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1786816, Length=388, Percent_Identity=25, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788627, Length=280, Percent_Identity=26.7857142857143, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=197, Percent_Identity=35.5329949238579, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=197, Percent_Identity=35.5329949238579, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=22.5806451612903, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=199, Percent_Identity=29.6482412060301, Blast_Score=104, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=288, Percent_Identity=28.4722222222222, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6320317, Length=343, Percent_Identity=22.7405247813411, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573069, Length=322, Percent_Identity=25.1552795031056, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646114, Length=322, Percent_Identity=25.1552795031056, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28573067, Length=322, Percent_Identity=25.1552795031056, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28573065, Length=322, Percent_Identity=25.1552795031056, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI18859735, Length=351, Percent_Identity=20.7977207977208, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43262; Mature: 43262

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
TLYPPIMGIPELRHMGCEWMYRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIP
EECCCCCCCHHHHHCCHHHHEECCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEC
SPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKACTTKSKILILNNATNPTGALY
CCCCCCCHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHCCCCEEEEEECCCCCCCCEE
TQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
EHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCCCEEEEECCCHHHHHHEEEEEECCCCCCC
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRN
CCEEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHH
CLLRTLHDYLGLTITPPISSLYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGK
HHHHHHHHHCCEEECCCHHHEEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCEEECC
EGYVRLSFGGNEDDLKSGIYALAQWLHR
CCEEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
TLYPPIMGIPELRHMGCEWMYRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIP
EECCCCCCCHHHHHCCHHHHEECCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEC
SPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKACTTKSKILILNNATNPTGALY
CCCCCCCHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHCCCCEEEEEECCCCCCCCEE
TQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
EHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCCCEEEEECCCHHHHHHEEEEEECCCCCCC
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRN
CCEEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHH
CLLRTLHDYLGLTITPPISSLYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGK
HHHHHHHHHCCEEECCCHHHEEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCEEECC
EGYVRLSFGGNEDDLKSGIYALAQWLHR
CCEEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]