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The map label for this gene is aroF

Identifier: 52842738

GI number: 52842738

Start: 2862296

End: 2863339

Strand: Direct

Name: aroF

Synonym: lpg2530

Alternate gene names: 52842738

Gene position: 2862296-2863339 (Clockwise)

Preceding gene: 52842736

Following gene: 52842739

Centisome position: 84.24

GC content: 42.82

Gene sequence:

>1044_bases
ATGAGTTATTCCATCTTAAAAAAACTGCCACCAATAGAAAAAATTATCCGGGAATTGCCACTATCCCACCCCGCCTATCT
ACAAATTGCCCAAGACCGACAAGAGGTCAAAGCTATTTTGGAAGGGCGAGATAAACGTCTTTTGATGATAGTTGGTCCTT
GTTCAGCATGGCCTAAAAAAGCGGTATTGGAATACGCTGAGCGTTTGGTACAACTCAACAGCAAAGTAAAACACGCTTTA
AAATTAATCATGCGCGTTTACATTCAAAAGCCAAGAACCACCAAAGGCTGGACTGGACCGGTGAATCAACCCGATTTATT
TTCAACTCCTGATATTGAGGCAGGTATAAAATATACCCGGGACATGATGATAAAAGTCATTCAAATGGGGCTCCCTATCG
CTGATGAGGCTCTTTTCACCCATAATGCCAAAGGATTTCTTGAACTTCTGTCCTGGGTTGCAATAGGCGCCCGTAGTTCA
GAGGATCAAGAGCATCGAATTTTTGCCTCCGCCCTTGACTGTGCCGTAGGATTAAAAAACCCTACACATGGTTCACTCGC
TGTCGGAGTAAACAGCCTGGTTGCATCACAGCATCCTCATGTCGCTGTCTTCGATGGCTATGAAGTACAAACCCATGGTA
ATCATCATGCTCATCTCGTTCTGCGTGGTTCAAACCAAGCTCCCAATTACTCTGTTTCTCATCTGGAGGAAGTCATGTAC
TACATGGGCATGCATCAGATAGTGAACCCTTCTGTCATTATTGATGTTAGCCATGACAACTGTCTGGTGAATGGGAAAAA
AAATCATCAGCTACAACCAGAGATTGCATTTAATATTCTGGAAAGCATCAAAAACAGACCTGATTTAAAACAACTGGTCA
AGGGATTCATGGTAGAAAGTTTCATCAAAGAAGGTAATCAAAAATTAGATTCTATCAATCCCGATAACATTGATTTAAGC
GGGTTATCCGTTACCGATCCTTGCCTCAGTTGGGAGAAGACAGAATCGTTCCTGTTGGAACTGGCAGAGAGGGAAGCGTT
ATGA

Upstream 100 bases:

>100_bases
CTAATAAGGGGGTTGGGTACAAAAGAGGAGTGTGAACGATGAACCATCAATGTCAAATTCATCATCCATCTAAAGCGCTT
TCTGGCTTGAGGAGGATACG

Downstream 100 bases:

>100_bases
AGAATCTCGTTGAAGAAAAAGAAGCCTTTCGCTTCGGTGTTTCTGGAGATATCGGATCATTTTCTGAGGAAGCGGCTTTG
CTTTATGCCAGGAAAAAAGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSYSILKKLPPIEKIIRELPLSHPAYLQIAQDRQEVKAILEGRDKRLLMIVGPCSAWPKKAVLEYAERLVQLNSKVKHAL
KLIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIEAGIKYTRDMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSS
EDQEHRIFASALDCAVGLKNPTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMY
YMGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVESFIKEGNQKLDSINPDNIDLS
GLSVTDPCLSWEKTESFLLELAEREAL

Sequences:

>Translated_347_residues
MSYSILKKLPPIEKIIRELPLSHPAYLQIAQDRQEVKAILEGRDKRLLMIVGPCSAWPKKAVLEYAERLVQLNSKVKHAL
KLIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIEAGIKYTRDMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSS
EDQEHRIFASALDCAVGLKNPTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMY
YMGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVESFIKEGNQKLDSINPDNIDLS
GLSVTDPCLSWEKTESFLLELAEREAL
>Mature_346_residues
SYSILKKLPPIEKIIRELPLSHPAYLQIAQDRQEVKAILEGRDKRLLMIVGPCSAWPKKAVLEYAERLVQLNSKVKHALK
LIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIEAGIKYTRDMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSSE
DQEHRIFASALDCAVGLKNPTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMYY
MGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVESFIKEGNQKLDSINPDNIDLSG
LSVTDPCLSWEKTESFLLELAEREAL

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=337, Percent_Identity=40.9495548961424, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1787996, Length=341, Percent_Identity=35.7771260997067, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1786969, Length=340, Percent_Identity=37.0588235294118, Blast_Score=216, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6319726, Length=350, Percent_Identity=35.7142857142857, Blast_Score=206, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320240, Length=348, Percent_Identity=35.0574712643678, Blast_Score=199, Evalue=4e-52,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38888; Mature: 38757

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSILKKLPPIEKIIRELPLSHPAYLQIAQDRQEVKAILEGRDKRLLMIVGPCSAWPKK
CCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
AVLEYAERLVQLNSKVKHALKLIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIEAGIKYTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSSEDQEHRIFASALDCAVGLKN
HHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
PTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMY
CCCCCHHHHHHHHHHCCCCCEEEECCEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHH
YMGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVES
HHHHHHHCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FIKEGNQKLDSINPDNIDLSGLSVTDPCLSWEKTESFLLELAEREAL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYSILKKLPPIEKIIRELPLSHPAYLQIAQDRQEVKAILEGRDKRLLMIVGPCSAWPKK
CCHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
AVLEYAERLVQLNSKVKHALKLIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIEAGIKYTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSSEDQEHRIFASALDCAVGLKN
HHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
PTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMY
CCCCCHHHHHHHHHHCCCCCEEEECCEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHH
YMGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVES
HHHHHHHCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FIKEGNQKLDSINPDNIDLSGLSVTDPCLSWEKTESFLLELAEREAL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]