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The map label for this gene is pilE

Identifier: 52842132

GI number: 52842132

Start: 2137668

End: 2138096

Strand: Reverse

Name: pilE

Synonym: lpg1914

Alternate gene names: 52842132

Gene position: 2138096-2137668 (Counterclockwise)

Preceding gene: 52842133

Following gene: 52842129

Centisome position: 62.93

GC content: 44.99

Gene sequence:

>429_bases
ATGCCAGGTGACGTTATGAGAATGAAAGGATTTACTTTAATCGAGCTGATGATCGTTGCCGCTATCCTTGGGATTCTGGT
TGCCATCGCAATTCCAGCCTATCAGGACTATACCATCAGAGCACGGGTGGTCGAAGGATTGGAAATGGCTTCGGCCGCTA
AATTAGCTGTTGTTGAAACGAGTTTAATTGATAACACTTTGCCAGCAAATCAGGCAGATACGGGCTATACCAGTCCTGCC
CCAACAATTAATGTAGCCTCTATAGCCATTGGTAATCAAGGCATTATTACCATTACCTACACTGCAAACGCAGGTAATGG
TACCATTACAATGGTTCCCACAATAGATGCCACTAACAGAATACTCACTTGGGATTGCACTGGTGGTACCCTGATTAGTA
AATATCGTCCAGCCTACTGCCGCCCTTAA

Upstream 100 bases:

>100_bases
CAGAAATGTTTTGAAAGAAGCTTGTCAAGCTATTTAGTCAGCAGAAGGATTTTTAAATCATAGAGTTGGCATTGAATTTG
CGTGATATCAGTTAGATGCA

Downstream 100 bases:

>100_bases
TCTTGGTTGATTTTTTTAGCCACTAACTGGTTTTTTAGTCGGACATAATCTGGCAATCCATTTTTGTAATTTGGATAAGC
TTCACCTTGAATCAAAGGGG

Product: fimbrial protein, type IV pilin, PilE

Products: NA

Alternate protein names: MS11 antigen; Pilin [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MPGDVMRMKGFTLIELMIVAAILGILVAIAIPAYQDYTIRARVVEGLEMASAAKLAVVETSLIDNTLPANQADTGYTSPA
PTINVASIAIGNQGIITITYTANAGNGTITMVPTIDATNRILTWDCTGGTLISKYRPAYCRP

Sequences:

>Translated_142_residues
MPGDVMRMKGFTLIELMIVAAILGILVAIAIPAYQDYTIRARVVEGLEMASAAKLAVVETSLIDNTLPANQADTGYTSPA
PTINVASIAIGNQGIITITYTANAGNGTITMVPTIDATNRILTWDCTGGTLISKYRPAYCRP
>Mature_141_residues
PGDVMRMKGFTLIELMIVAAILGILVAIAIPAYQDYTIRARVVEGLEMASAAKLAVVETSLIDNTLPANQADTGYTSPAP
TINVASIAIGNQGIITITYTANAGNGTITMVPTIDATNRILTWDCTGGTLISKYRPAYCRP

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=122, Percent_Identity=31.1475409836066, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 15006; Mature: 14874

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGDVMRMKGFTLIELMIVAAILGILVAIAIPAYQDYTIRARVVEGLEMASAAKLAVVET
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCEEEEEEH
SLIDNTLPANQADTGYTSPAPTINVASIAIGNQGIITITYTANAGNGTITMVPTIDATNR
HHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCEEEEEEECCCCCE
ILTWDCTGGTLISKYRPAYCRP
EEEEECCCCEEECCCCCCCCCC
>Mature Secondary Structure 
PGDVMRMKGFTLIELMIVAAILGILVAIAIPAYQDYTIRARVVEGLEMASAAKLAVVET
CCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCEEEEEEH
SLIDNTLPANQADTGYTSPAPTINVASIAIGNQGIITITYTANAGNGTITMVPTIDATNR
HHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCEEEEEEECCCCCE
ILTWDCTGGTLISKYRPAYCRP
EEEEECCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6148752; 2872674; 1671354; 1348857; 6143785; 7477282; 10048019 [H]