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The map label for this gene is rhtC [H]

Identifier: 52841443

GI number: 52841443

Start: 1337473

End: 1338144

Strand: Reverse

Name: rhtC [H]

Synonym: lpg1211

Alternate gene names: 52841443

Gene position: 1338144-1337473 (Counterclockwise)

Preceding gene: 52841447

Following gene: 52841440

Centisome position: 39.38

GC content: 34.52

Gene sequence:

>672_bases
CTGAAAAACTTAATAAAAAAACTTGGAGTTTCTATGGAACAATGGCATCAATTTACTCTACTATTTCCTTTAATTATTTT
AGTTTTTATTTCATTAATCAGTCCTGGGCCAGATTTTGCTATCACAGTCAAAAACAGCTTGGCTTATTCCAGAAAGAGTG
GTTTATTAACCGCATTAGGAATAGCTTTGGGCAGCTTGGTTCATATCAGTTACACTCTTCTTGGATTAGGCTTGTTTATT
ACCAAAACGCCTATAATACTGCATATCATCCAGTATCTAGGCGCTGGATACCTCTTTTATATTGGCCTTAAAAATCTTGG
TGCCAAGCCAAATGCTGACCAAATAGGAAGTTATACAACGAACAACGATTTAAAACCAAGCGAAGCTTTTTTCAATGGGT
TTATAACGAATTTATTGAATCCCAAAGCCATGCTCTTTTTTATCAGTTTATTTTCAGTGCTTATGCCCAGAGAAATCTCA
ATCTCCACCAAATTATTCCTGGCAATTGTCCTCTTTCTACAAACATTGTTATGGTTTTCTTTTGTTGCATTCAGTCTTTC
TGGAAAAAATACGCGTACGAAATTTCAAAGAATTAGCTATTGGATTGAGCGTATTACAGGTGTCATTTTAATTGCATTGG
CATTAAAATTATTGCTAAGCCAATTGGTCTAA

Upstream 100 bases:

>100_bases
GAGGTGAGATACATTTAGAGAGTTTAAGTCATAGAAATAATGTCGTATTCACTAAATGTAAAACCAAAAAAGAGCGTTTA
AAAATTAGCTATGATATTGG

Downstream 100 bases:

>100_bases
TGCTCAGATAGAAGAACATACAAAATCCATCAAACTTTTATTAAGGAATTCTGTATACGATATAAAACATGCTTCGCTAA
CCTGTGATCAGAGACTAATT

Product: amino acid transporter LysE

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKNLIKKLGVSMEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRKSGLLTALGIALGSLVHISYTLLGLGLFI
TKTPIILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYTTNNDLKPSEAFFNGFITNLLNPKAMLFFISLFSVLMPREIS
ISTKLFLAIVLFLQTLLWFSFVAFSLSGKNTRTKFQRISYWIERITGVILIALALKLLLSQLV

Sequences:

>Translated_223_residues
MKNLIKKLGVSMEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRKSGLLTALGIALGSLVHISYTLLGLGLFI
TKTPIILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYTTNNDLKPSEAFFNGFITNLLNPKAMLFFISLFSVLMPREIS
ISTKLFLAIVLFLQTLLWFSFVAFSLSGKNTRTKFQRISYWIERITGVILIALALKLLLSQLV
>Mature_223_residues
MKNLIKKLGVSMEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRKSGLLTALGIALGSLVHISYTLLGLGLFI
TKTPIILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYTTNNDLKPSEAFFNGFITNLLNPKAMLFFISLFSVLMPREIS
ISTKLFLAIVLFLQTLLWFSFVAFSLSGKNTRTKFQRISYWIERITGVILIALALKLLLSQLV

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=205, Percent_Identity=30.7317073170732, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1786522, Length=210, Percent_Identity=29.5238095238095, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788099, Length=128, Percent_Identity=35.9375, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 24880; Mature: 24880

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLIKKLGVSMEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRKSGLLTALG
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHH
IALGSLVHISYTLLGLGLFITKTPIILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHCCCCCCHHHCCCCCC
NNDLKPSEAFFNGFITNLLNPKAMLFFISLFSVLMPREISISTKLFLAIVLFLQTLLWFS
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FVAFSLSGKNTRTKFQRISYWIERITGVILIALALKLLLSQLV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNLIKKLGVSMEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRKSGLLTALG
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHH
IALGSLVHISYTLLGLGLFITKTPIILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHCCCCCCHHHCCCCCC
NNDLKPSEAFFNGFITNLLNPKAMLFFISLFSVLMPREISISTKLFLAIVLFLQTLLWFS
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FVAFSLSGKNTRTKFQRISYWIERITGVILIALALKLLLSQLV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]