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The map label for this gene is silP [H]

Identifier: 52841258

GI number: 52841258

Start: 1121779

End: 1123989

Strand: Direct

Name: silP [H]

Synonym: lpg1024

Alternate gene names: 52841258

Gene position: 1121779-1123989 (Clockwise)

Preceding gene: 52841257

Following gene: 52841259

Centisome position: 33.02

GC content: 47.72

Gene sequence:

>2211_bases
ATGAAACACGACCACCATCAAGGACATACCCATTCTGGTAAAGGACATGCTTGTCATCACGAACATAATTCTCCCAAGAC
TCAGCAAGCCTCTTCCAAAATGGAGGGGCCTATTGTTTATACGTGTCCCATGCACCCAGAAATTCGCCAATCTGCCCCTG
GTCATTGTCCTCTTTGTGGTATGGCTTTAGAACCGGAAACGGTGACGGTTTCGGAGGTTGTGAGCCCTGAATATCTTGAT
ATGAGACGTCGATTTTGGATTGCATTGATGTTAACTATACCTGTTGTGATATTGGAGATGGGTGGACATGGTTTGAAGCA
TTTTATTTCTGGTAATGGTTCCAGTTGGATCCAATTGCTTCTTGCCACGCCAGTGGTGTTATGGGGAGGTTGGCCTTTTT
TCAAGCGCGGTTGGCAGTCTCTAAAAACAGGCCAACTCAATATGTTTACCTTGATTGCCATGGGTATTGGTGTGGCGTGG
ATTTACAGTATGGTGGCTGTCCTTTGGCCAGGTGTATTTCCCCATGCGTTTAGAAGTCAAGAAGGAGTAGTTGCTGTTTA
TTTTGAAGCGGCAGCAGTGATTACTACGCTTGTCTTGTTGGGGCAAGTGCTGGAACTAAAAGCTCGAGAACAAACGGGTA
GTGCCATCCGTGCCTTGTTAAAATTGGTCCCTGAAAGTGCACACCGAATTAAGGAAGATGGCAGTGAAGAGGAGGTGTCC
CTGGATAACGTTGCCGTTGGTGATTTGTTGCGTGTTCGGCCTGGTGAAAAAATACCAGTGGATGGTGAAGTGCAAGAAGG
ACGAAGCTTTGTCGATGAATCCATGGTGACAGGTGAGCCCATTCCAGTTGCTAAAGAGGCCAGCGCTAAAGTTATTGGTG
CTACGATTAATCAGACGGGTAGCTTTGTCATGAAAGCGCTGCATGTGGGCAGTGATACCATGCTTGCACGCATTGTGCAG
ATGGTGAGTGATGCCCAACGAAGCCGTGCGCCGATTCAGCGACTAGCCGATACCGTCTCAGGATGGTTTGTGCCCGCTGT
GATTTTGGTTGCGGTGCTGTCTTTTATTGTGTGGGCACTGTTGGGTCCGCAACCAGCGCTTAGCTATGGTTTAATCGCTG
CTGTGTCAGTACTCATCATCGCTTGCCCTTGTGCGTTAGGTTTAGCAACGCCCATGTCCATTATGGTCGGTGTTGGAAAA
GGAGCACAAAGCGGGGTATTGATTAAAAATGCCGAAGCGTTGGAACGAATGGAGAAGGTCAATACCCTGGTGGTCGATAA
AACGGGCACGCTTACTGAAGGTCACCCTAAATTGACACGCATTGTGACCGATGATTTCGTGGAGGATAATGCTTTAGCAT
TAGCTGCGGCACTTGAGCATCAAAGTGAACATCCGCTGGCCAATGCTATTGTGCATGCTGCAAAAGAAAAAGGATTGTCC
CTTGGATCAGTCGAAGCGTTTGAAGCGCCCACTGGAAAAGGGGTTGTAGGTCAGGTAGACGGCCATCATGTTGCTATTGG
TAACGCCAGATTAATGCAAGAGCATGGAGGCGATAATGCCCCTCTTTTTGAAAAGGCTGATGAACTTCGTGGTAAAGGCG
CCTCAGTCATGTTTATGGCGGTTGATGGTAAAACAGTAGCTCTCTTGGTGGTTGAAGACCCTATTAAATCGAGTACTCCA
GAGACCATCCTCGAACTTCAGCAAAGTGGCATTGAAATTGTCATGCTCACCGGAGATAGCAAAAGAACAGCTGAAGCGGT
AGCAGGTACACTTGGCATCAAAAAGGTAGTAGCTGAAATCATGCCTGAAGACAAGAGCCGCATCGTGAGTGAATTAAAAG
ACAAAGGTCTTATTGTTGCCATGGCAGGAGATGGGGTGAATGATGCCCCAGCGCTTGCCAAAGCTGATATTGGTATTGCC
ATGGGAACAGGCACTGATGTGGCCATCGAAAGTGCTGGTGTTACCTTGTTGCATGGAGATTTGCGTGGTATCGCCAAAGC
GCGACGTTTGTCAGAAAGTACCATGAGCAACATTCGCCAAAATCTTTTCTTCGCCTTTATTTATAATGTACTGGGTGTGC
CCTTGGCTGCTGGGGTTTTGTACCCTCTAACTGGCTTGCTCTTAAGTCCTATGATTGCAGCAGCAGCGATGGCGCTTTCT
TCAGTGTCAGTGATTATCAATGCGCTGAGACTAAAGAGAGTGACACTATGA

Upstream 100 bases:

>100_bases
GGGTGGGCATGGTGGTCATGGCGGTGCTGGGCATTAAGCCCATTCGCTGCATTGGTAAATCAAGCCAAAGCATACTCACA
CTTAACAGGTAGGGCAAACC

Downstream 100 bases:

>100_bases
AAAAAAGGATGGTCAGATGAGCTTAAGATGTGATTAGTCTTTATTGTATTGGCTAAACAAAAATCATCACGTTCACTTCA
TTGAAGAAAAATCAAGTCTA

Product: copper efflux ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 736; Mature: 736

Protein sequence:

>736_residues
MKHDHHQGHTHSGKGHACHHEHNSPKTQQASSKMEGPIVYTCPMHPEIRQSAPGHCPLCGMALEPETVTVSEVVSPEYLD
MRRRFWIALMLTIPVVILEMGGHGLKHFISGNGSSWIQLLLATPVVLWGGWPFFKRGWQSLKTGQLNMFTLIAMGIGVAW
IYSMVAVLWPGVFPHAFRSQEGVVAVYFEAAAVITTLVLLGQVLELKAREQTGSAIRALLKLVPESAHRIKEDGSEEEVS
LDNVAVGDLLRVRPGEKIPVDGEVQEGRSFVDESMVTGEPIPVAKEASAKVIGATINQTGSFVMKALHVGSDTMLARIVQ
MVSDAQRSRAPIQRLADTVSGWFVPAVILVAVLSFIVWALLGPQPALSYGLIAAVSVLIIACPCALGLATPMSIMVGVGK
GAQSGVLIKNAEALERMEKVNTLVVDKTGTLTEGHPKLTRIVTDDFVEDNALALAAALEHQSEHPLANAIVHAAKEKGLS
LGSVEAFEAPTGKGVVGQVDGHHVAIGNARLMQEHGGDNAPLFEKADELRGKGASVMFMAVDGKTVALLVVEDPIKSSTP
ETILELQQSGIEIVMLTGDSKRTAEAVAGTLGIKKVVAEIMPEDKSRIVSELKDKGLIVAMAGDGVNDAPALAKADIGIA
MGTGTDVAIESAGVTLLHGDLRGIAKARRLSESTMSNIRQNLFFAFIYNVLGVPLAAGVLYPLTGLLLSPMIAAAAMALS
SVSVIINALRLKRVTL

Sequences:

>Translated_736_residues
MKHDHHQGHTHSGKGHACHHEHNSPKTQQASSKMEGPIVYTCPMHPEIRQSAPGHCPLCGMALEPETVTVSEVVSPEYLD
MRRRFWIALMLTIPVVILEMGGHGLKHFISGNGSSWIQLLLATPVVLWGGWPFFKRGWQSLKTGQLNMFTLIAMGIGVAW
IYSMVAVLWPGVFPHAFRSQEGVVAVYFEAAAVITTLVLLGQVLELKAREQTGSAIRALLKLVPESAHRIKEDGSEEEVS
LDNVAVGDLLRVRPGEKIPVDGEVQEGRSFVDESMVTGEPIPVAKEASAKVIGATINQTGSFVMKALHVGSDTMLARIVQ
MVSDAQRSRAPIQRLADTVSGWFVPAVILVAVLSFIVWALLGPQPALSYGLIAAVSVLIIACPCALGLATPMSIMVGVGK
GAQSGVLIKNAEALERMEKVNTLVVDKTGTLTEGHPKLTRIVTDDFVEDNALALAAALEHQSEHPLANAIVHAAKEKGLS
LGSVEAFEAPTGKGVVGQVDGHHVAIGNARLMQEHGGDNAPLFEKADELRGKGASVMFMAVDGKTVALLVVEDPIKSSTP
ETILELQQSGIEIVMLTGDSKRTAEAVAGTLGIKKVVAEIMPEDKSRIVSELKDKGLIVAMAGDGVNDAPALAKADIGIA
MGTGTDVAIESAGVTLLHGDLRGIAKARRLSESTMSNIRQNLFFAFIYNVLGVPLAAGVLYPLTGLLLSPMIAAAAMALS
SVSVIINALRLKRVTL
>Mature_736_residues
MKHDHHQGHTHSGKGHACHHEHNSPKTQQASSKMEGPIVYTCPMHPEIRQSAPGHCPLCGMALEPETVTVSEVVSPEYLD
MRRRFWIALMLTIPVVILEMGGHGLKHFISGNGSSWIQLLLATPVVLWGGWPFFKRGWQSLKTGQLNMFTLIAMGIGVAW
IYSMVAVLWPGVFPHAFRSQEGVVAVYFEAAAVITTLVLLGQVLELKAREQTGSAIRALLKLVPESAHRIKEDGSEEEVS
LDNVAVGDLLRVRPGEKIPVDGEVQEGRSFVDESMVTGEPIPVAKEASAKVIGATINQTGSFVMKALHVGSDTMLARIVQ
MVSDAQRSRAPIQRLADTVSGWFVPAVILVAVLSFIVWALLGPQPALSYGLIAAVSVLIIACPCALGLATPMSIMVGVGK
GAQSGVLIKNAEALERMEKVNTLVVDKTGTLTEGHPKLTRIVTDDFVEDNALALAAALEHQSEHPLANAIVHAAKEKGLS
LGSVEAFEAPTGKGVVGQVDGHHVAIGNARLMQEHGGDNAPLFEKADELRGKGASVMFMAVDGKTVALLVVEDPIKSSTP
ETILELQQSGIEIVMLTGDSKRTAEAVAGTLGIKKVVAEIMPEDKSRIVSELKDKGLIVAMAGDGVNDAPALAKADIGIA
MGTGTDVAIESAGVTLLHGDLRGIAKARRLSESTMSNIRQNLFFAFIYNVLGVPLAAGVLYPLTGLLLSPMIAAAAMALS
SVSVIINALRLKRVTL

Specific function: Component of the sil cation-efflux system that confers resistance to silver [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=661, Percent_Identity=37.5189107413011, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI115529486, Length=743, Percent_Identity=34.5895020188425, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI55743073, Length=517, Percent_Identity=37.5241779497099, Blast_Score=329, Evalue=7e-90,
Organism=Homo sapiens, GI28373107, Length=169, Percent_Identity=35.5029585798817, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI28373115, Length=169, Percent_Identity=35.5029585798817, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI28373111, Length=169, Percent_Identity=35.5029585798817, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI28373105, Length=169, Percent_Identity=35.5029585798817, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI28373109, Length=169, Percent_Identity=35.5029585798817, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI28373103, Length=169, Percent_Identity=35.5029585798817, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI28373113, Length=169, Percent_Identity=35.5029585798817, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI48762691, Length=186, Percent_Identity=34.4086021505376, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI48762689, Length=186, Percent_Identity=34.4086021505376, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI48255947, Length=227, Percent_Identity=29.5154185022026, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI48762685, Length=186, Percent_Identity=34.4086021505376, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI48255945, Length=227, Percent_Identity=29.5154185022026, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI48762687, Length=186, Percent_Identity=34.4086021505376, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI209413709, Length=184, Percent_Identity=30.9782608695652, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI24638454, Length=184, Percent_Identity=30.9782608695652, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI4502285, Length=184, Percent_Identity=30.9782608695652, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI118498343, Length=160, Percent_Identity=34.375, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI310128958, Length=169, Percent_Identity=31.9526627218935, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI153946397, Length=243, Percent_Identity=29.2181069958848, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI10835220, Length=169, Percent_Identity=31.9526627218935, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI51944966, Length=243, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI27886529, Length=169, Percent_Identity=31.9526627218935, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI237681109, Length=238, Percent_Identity=26.0504201680672, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI21361181, Length=238, Percent_Identity=26.0504201680672, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI237681111, Length=238, Percent_Identity=26.0504201680672, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI297374799, Length=238, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI83700225, Length=238, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI4502271, Length=241, Percent_Identity=25.3112033195021, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI22748667, Length=241, Percent_Identity=24.896265560166, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1786691, Length=658, Percent_Identity=45.1367781155015, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1789879, Length=544, Percent_Identity=36.2132352941176, Blast_Score=272, Evalue=5e-74,
Organism=Escherichia coli, GI1786914, Length=451, Percent_Identity=31.0421286031042, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI2367363, Length=634, Percent_Identity=23.9747634069401, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17556548, Length=722, Percent_Identity=35.595567867036, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71997262, Length=599, Percent_Identity=24.5409015025042, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71997275, Length=598, Percent_Identity=24.5819397993311, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71997269, Length=586, Percent_Identity=24.7440273037543, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17554158, Length=169, Percent_Identity=32.5443786982249, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193210130, Length=169, Percent_Identity=32.5443786982249, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71988506, Length=169, Percent_Identity=32.5443786982249, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541776, Length=199, Percent_Identity=31.1557788944724, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71999440, Length=186, Percent_Identity=31.1827956989247, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25152707, Length=186, Percent_Identity=31.1827956989247, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71999438, Length=186, Percent_Identity=31.1827956989247, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17557770, Length=183, Percent_Identity=30.0546448087432, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17557486, Length=236, Percent_Identity=28.8135593220339, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566766, Length=183, Percent_Identity=30.0546448087432, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559224, Length=240, Percent_Identity=25.8333333333333, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17531459, Length=361, Percent_Identity=22.1606648199446, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203354, Length=177, Percent_Identity=28.2485875706215, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193203356, Length=177, Percent_Identity=28.2485875706215, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320475, Length=640, Percent_Identity=36.09375, Blast_Score=378, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6319772, Length=637, Percent_Identity=31.2401883830455, Blast_Score=293, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6325221, Length=572, Percent_Identity=25.5244755244755, Blast_Score=134, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6321430, Length=566, Percent_Identity=25.0883392226148, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6321271, Length=636, Percent_Identity=24.0566037735849, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321432, Length=182, Percent_Identity=31.3186813186813, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320243, Length=237, Percent_Identity=26.5822784810127, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320244, Length=237, Percent_Identity=26.5822784810127, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221329854, Length=774, Percent_Identity=31.7829457364341, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24668708, Length=201, Percent_Identity=33.8308457711443, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281366617, Length=201, Percent_Identity=33.8308457711443, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24668704, Length=201, Percent_Identity=33.8308457711443, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24668696, Length=201, Percent_Identity=33.8308457711443, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI161085803, Length=201, Percent_Identity=33.8308457711443, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24762455, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24762453, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24762447, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24762457, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24762449, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24762445, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24762451, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17136664, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281366676, Length=240, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45553441, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24648580, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24648578, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45553437, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281362164, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45553435, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45553439, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648576, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648582, Length=281, Percent_Identity=22.7758007117438, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR007029 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase; PF04945 YHS [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 78245; Mature: 78245

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHDHHQGHTHSGKGHACHHEHNSPKTQQASSKMEGPIVYTCPMHPEIRQSAPGHCPLCG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHCCCCCCCEEC
MALEPETVTVSEVVSPEYLDMRRRFWIALMLTIPVVILEMGGHGLKHFISGNGSSWIQLL
CCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
LATPVVLWGGWPFFKRGWQSLKTGQLNMFTLIAMGIGVAWIYSMVAVLWPGVFPHAFRSQ
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
EGVVAVYFEAAAVITTLVLLGQVLELKAREQTGSAIRALLKLVPESAHRIKEDGSEEEVS
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCC
LDNVAVGDLLRVRPGEKIPVDGEVQEGRSFVDESMVTGEPIPVAKEASAKVIGATINQTG
CCCEECCCHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHH
SFVMKALHVGSDTMLARIVQMVSDAQRSRAPIQRLADTVSGWFVPAVILVAVLSFIVWAL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGPQPALSYGLIAAVSVLIIACPCALGLATPMSIMVGVGKGAQSGVLIKNAEALERMEKV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCCCEEEECHHHHHHHHHH
NTLVVDKTGTLTEGHPKLTRIVTDDFVEDNALALAAALEHQSEHPLANAIVHAAKEKGLS
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
LGSVEAFEAPTGKGVVGQVDGHHVAIGNARLMQEHGGDNAPLFEKADELRGKGASVMFMA
CCCCHHCCCCCCCCCEEECCCCEEEECCHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEE
VDGKTVALLVVEDPIKSSTPETILELQQSGIEIVMLTGDSKRTAEAVAGTLGIKKVVAEI
ECCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
MPEDKSRIVSELKDKGLIVAMAGDGVNDAPALAKADIGIAMGTGTDVAIESAGVTLLHGD
CCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCEEECCCCCEEEECCCEEEEEHH
LRGIAKARRLSESTMSNIRQNLFFAFIYNVLGVPLAAGVLYPLTGLLLSPMIAAAAMALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVSVIINALRLKRVTL
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHDHHQGHTHSGKGHACHHEHNSPKTQQASSKMEGPIVYTCPMHPEIRQSAPGHCPLCG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHCCCCCCCEEC
MALEPETVTVSEVVSPEYLDMRRRFWIALMLTIPVVILEMGGHGLKHFISGNGSSWIQLL
CCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
LATPVVLWGGWPFFKRGWQSLKTGQLNMFTLIAMGIGVAWIYSMVAVLWPGVFPHAFRSQ
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
EGVVAVYFEAAAVITTLVLLGQVLELKAREQTGSAIRALLKLVPESAHRIKEDGSEEEVS
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCC
LDNVAVGDLLRVRPGEKIPVDGEVQEGRSFVDESMVTGEPIPVAKEASAKVIGATINQTG
CCCEECCCHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHH
SFVMKALHVGSDTMLARIVQMVSDAQRSRAPIQRLADTVSGWFVPAVILVAVLSFIVWAL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGPQPALSYGLIAAVSVLIIACPCALGLATPMSIMVGVGKGAQSGVLIKNAEALERMEKV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCCCEEEECHHHHHHHHHH
NTLVVDKTGTLTEGHPKLTRIVTDDFVEDNALALAAALEHQSEHPLANAIVHAAKEKGLS
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
LGSVEAFEAPTGKGVVGQVDGHHVAIGNARLMQEHGGDNAPLFEKADELRGKGASVMFMA
CCCCHHCCCCCCCCCEEECCCCEEEECCHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEE
VDGKTVALLVVEDPIKSSTPETILELQQSGIEIVMLTGDSKRTAEAVAGTLGIKKVVAEI
ECCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
MPEDKSRIVSELKDKGLIVAMAGDGVNDAPALAKADIGIAMGTGTDVAIESAGVTLLHGD
CCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCEEECCCCCEEEECCCEEEEEHH
LRGIAKARRLSESTMSNIRQNLFFAFIYNVLGVPLAAGVLYPLTGLLLSPMIAAAAMALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVSVIINALRLKRVTL
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]