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The map label for this gene is yegE

Identifier: 52841259

GI number: 52841259

Start: 1124129

End: 1125010

Strand: Direct

Name: yegE

Synonym: lpg1025

Alternate gene names: 52841259

Gene position: 1124129-1125010 (Clockwise)

Preceding gene: 52841258

Following gene: 52841260

Centisome position: 33.08

GC content: 40.25

Gene sequence:

>882_bases
ATGGTTATCCCAGTTGTTATGATAGTGTTTGGTATTGCCTTTCTTGCTAATGGAGCTTATTTAATCAATGGATTAGTGCA
ACAAAGGAATCACTATCGGCGACTAGGGCTTGTTTCTCTTGCTTTTATTGGCATTTTTATCCTCAGTTATTTAGCCAGCA
TTTTTTATGGTTTATTGGTCGATCCTCATTGCCTTAATTATTTTTATGGCAGTGTGTTTTTGTTAGCGGCGACTTATATT
TATTTTTCATGTCATTTGGTGACTAAGACCATTCAAAAAGTGGAATTGATGGCTGACTTTAAAAGTCGCTACGAACTATT
AAGGCAGCATGCTCAGTATGATTCGTTGACTGGCTGTCATAACAGAGAGACCCTTTTTGAGGTTTTGAACACAAGGCTCC
AACAAATTAAGATGCATGGAGGATGGGTTATCGTTCTTTTTATTGATATGGATAAATTTAAGACGGTCAATGACCGTTAT
GGTCATGATGCGGGAGATAACACGTTACAAACATTTGGGCAACTCCTAACGCAGCGATTGCGAAAGGATGATATCGTGGC
TCGTTATGGTGGGGATGAGTTTATTGCCGTGATGGAAAACATCTCTATCGATGAGGCGAAAAAGATTGCTGAAAATCTTA
TCACTGTGACGAGACAATTGTTCAAAGAAGGTATTTTATCGGAGCTTAATCTAGGTTGCTCTATTGGCATCACTCAGATG
AATCCTCACTCGGCCTCAGTGAATACCGTCATCAAAGAAGCGGATTTGGCGTGCTACGCGGCAAAACAAAGAAAAATCAA
TGGCTCGGTTTGTGTCTATAGTCCAATGCTTGCAACAACAAACCATCCCATCGACACGAGTATCCATCCAATCGCTGACT
AG

Upstream 100 bases:

>100_bases
TTTATTGTATTGGCTAAACAAAAATCATCACGTTCACTTCATTGAAGAAAAATCAAGTCTATACTAAAGAAATAGTTCAG
ACTGTATTCAAGGCCAAATC

Downstream 100 bases:

>100_bases
AAAAAGAGAATGCATAAAACAGTCATCTTACTGCAGAAGCAGGTACGACATCATCTATTATTTTACAACCCATTGTTTAA
TGGCATTGGGTGGGAGATAC

Product: sensory box/GGDEF family protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MVIPVVMIVFGIAFLANGAYLINGLVQQRNHYRRLGLVSLAFIGIFILSYLASIFYGLLVDPHCLNYFYGSVFLLAATYI
YFSCHLVTKTIQKVELMADFKSRYELLRQHAQYDSLTGCHNRETLFEVLNTRLQQIKMHGGWVIVLFIDMDKFKTVNDRY
GHDAGDNTLQTFGQLLTQRLRKDDIVARYGGDEFIAVMENISIDEAKKIAENLITVTRQLFKEGILSELNLGCSIGITQM
NPHSASVNTVIKEADLACYAAKQRKINGSVCVYSPMLATTNHPIDTSIHPIAD

Sequences:

>Translated_293_residues
MVIPVVMIVFGIAFLANGAYLINGLVQQRNHYRRLGLVSLAFIGIFILSYLASIFYGLLVDPHCLNYFYGSVFLLAATYI
YFSCHLVTKTIQKVELMADFKSRYELLRQHAQYDSLTGCHNRETLFEVLNTRLQQIKMHGGWVIVLFIDMDKFKTVNDRY
GHDAGDNTLQTFGQLLTQRLRKDDIVARYGGDEFIAVMENISIDEAKKIAENLITVTRQLFKEGILSELNLGCSIGITQM
NPHSASVNTVIKEADLACYAAKQRKINGSVCVYSPMLATTNHPIDTSIHPIAD
>Mature_293_residues
MVIPVVMIVFGIAFLANGAYLINGLVQQRNHYRRLGLVSLAFIGIFILSYLASIFYGLLVDPHCLNYFYGSVFLLAATYI
YFSCHLVTKTIQKVELMADFKSRYELLRQHAQYDSLTGCHNRETLFEVLNTRLQQIKMHGGWVIVLFIDMDKFKTVNDRY
GHDAGDNTLQTFGQLLTQRLRKDDIVARYGGDEFIAVMENISIDEAKKIAENLITVTRQLFKEGILSELNLGCSIGITQM
NPHSASVNTVIKEADLACYAAKQRKINGSVCVYSPMLATTNHPIDTSIHPIAD

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=196, Percent_Identity=33.6734693877551, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87081977, Length=183, Percent_Identity=31.6939890710383, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787541, Length=173, Percent_Identity=33.5260115606936, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786584, Length=180, Percent_Identity=29.4444444444444, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=35.3658536585366, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081974, Length=152, Percent_Identity=33.5526315789474, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787262, Length=224, Percent_Identity=27.2321428571429, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082007, Length=170, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87081881, Length=159, Percent_Identity=31.4465408805031, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787802, Length=195, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=30.2469135802469, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788085, Length=162, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 33013; Mature: 33013

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIPVVMIVFGIAFLANGAYLINGLVQQRNHYRRLGLVSLAFIGIFILSYLASIFYGLLV
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPHCLNYFYGSVFLLAATYIYFSCHLVTKTIQKVELMADFKSRYELLRQHAQYDSLTGCH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NRETLFEVLNTRLQQIKMHGGWVIVLFIDMDKFKTVNDRYGHDAGDNTLQTFGQLLTQRL
CHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHCCCCHHCCCCCCCHHHHHHHHHHHHHH
RKDDIVARYGGDEFIAVMENISIDEAKKIAENLITVTRQLFKEGILSELNLGCSIGITQM
HHCCCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEEEC
NPHSASVNTVIKEADLACYAAKQRKINGSVCVYSPMLATTNHPIDTSIHPIAD
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVIPVVMIVFGIAFLANGAYLINGLVQQRNHYRRLGLVSLAFIGIFILSYLASIFYGLLV
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPHCLNYFYGSVFLLAATYIYFSCHLVTKTIQKVELMADFKSRYELLRQHAQYDSLTGCH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NRETLFEVLNTRLQQIKMHGGWVIVLFIDMDKFKTVNDRYGHDAGDNTLQTFGQLLTQRL
CHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHCCCCHHCCCCCCCHHHHHHHHHHHHHH
RKDDIVARYGGDEFIAVMENISIDEAKKIAENLITVTRQLFKEGILSELNLGCSIGITQM
HHCCCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEEEC
NPHSASVNTVIKEADLACYAAKQRKINGSVCVYSPMLATTNHPIDTSIHPIAD
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]