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The map label for this gene is recQ

Identifier: 52841103

GI number: 52841103

Start: 940306

End: 942132

Strand: Reverse

Name: recQ

Synonym: lpg0867

Alternate gene names: 52841103

Gene position: 942132-940306 (Counterclockwise)

Preceding gene: 52841107

Following gene: 52841102

Centisome position: 27.73

GC content: 39.57

Gene sequence:

>1827_bases
ATGGGAACTTTAGCGCAACCATCTTTTATAAATCCAAACGCATTAGCTGTTTTAAAAAAATATTTTGGATTTGATTCCTT
CAGACCTCCTCAGGAAAAAATAATTGAGGATGTCATTTCTGGGGAAGATGTACTGGTTTTGATGCCTACTGGAGGGGGAA
AATCGCTTTGCTATCAAATTCCAGCCATTGTCCGCCCTGGTGTTGGCATTGTAGTATCTCCTTTAATCGCGTTAATGGAA
GATCAAGTAACCGCTCTCAAACTGCAGGGTATTCGTGCGGCTTACTACAACTCATCCTTAACCGCCGAAGAGGCTAGAAA
TGTATTAAATCAATTACATCATAATGAATTGGATTTACTCTATATTGCTCCAGAACGTCTTATTAGTACCTCGTTTCTGG
ATCGGCTGTCAGAATGTACTATCTCTTTATTTGCTATCGATGAAGCACACTGTATTTCACAATGGGGACATGATTTTCGA
CCTGAATACGCCTGTTTAGGTTTACTGAAAACTAACTTTCCTGACATTCCTATGATTGCTCTGACAGCTACTGCCGATAA
GCAAACACGTGAGGATATTGTTACCAAGTTGAATTATCAACCCAAAAAATACGTTGTTTCATTCAATCGACCGAATATCC
ATTACAAAGTAGTTCCTAAAACAAATGCAGTGAAGCAATTAAATCTGTTTTTACAATCTGATACCCAGCAATCTGGAATT
ATTTATTGTGGAACCCGCCATACAGTCGAACATCTTACAGCGAAATTACAAGAACTTGGATTTAAAGCACGCGCTTATCA
TGCAGGCCTGCCTCATGCGGTGCGGCGTGAGGTGCAAAACCTTTTCAGATACGATCGCATTGATATTGTGGTAGCTACTA
TTGCTTTTGGAATGGGTATTGACAAGCCTAATGTTCGCTTTGTTGTTCACCATGATTTACCCAAAAGCATCGAAGGTTAC
TACCAGGAAACAGGTCGTGCAGGACGTGACGGATTACCGGCCAAGGCCCTTCTTCTTTATGATGCTGCGGATAGTGCCCG
TTTGCGGTCCTGGATCATGAACATTCCTCTTGAGGAGCAAAGACATATAGAAACCAATAAATTAAATCATATGCTTGCTT
TTGCTGAAGCGTCGCATTGTCGTCGTCAAATTTTATTACGCTATTTTGATGAACCTTCTCATACAGAATGTAAAAACTGT
GATGTCTGCGATAACCCACCGCAAACAGCCGATGCAACAGAAGATGCGCAAAAATTTTTATCGTGTATTTATCGATTAAA
ACAAAGCTATGGTTTAACTCATACTATTGATGTCCTGAGAGGTAGTTTATCTGAAAAAATCAAGCAGTCTGGGCATGAGC
ATTTAAGTACCTTTGGAATTGGGAAGGAGAAATCTGCCAATTATTGGAAGCATCTTGCCTGGCAATTAATTCATAAAGAT
TATTGTTTACAGGACATGAATCATTTTAATGTGTTACGCTTGACCCCAAAAGCGATTCCCCTCCTAAAAGGTGAAGAGAG
TATTTCATTAACCATTCCTAACAATGACCTGAATAGCAGTAAAAAGAAAGGCAAGCAGAATCCTTCCTTTAAACCTGAAA
GTAACCCATTATTTGAAAAGCTTCGTGCGTTAAGACGTCAGTTAGCCGATGAAGAAAACAAACCACCATTTATGATATTC
AGTGATGCCACATTACATGAAATGGCCCAATCAAAACCCAAAAACAGTAAGCAACTACTGAATGTATCTGGGGTTGGGCA
ACATAAATTAGCTCGTTATGGCCATTATTTTCTCGAAGCCTTAAACGAATTTTCAGAAGTCGAGTGA

Upstream 100 bases:

>100_bases
ATTTATTGATTTTAGTCATTGGATTTATTTATGACGCTTTCTTAAAAAATGATATTATTGCGAATTTTTAGCGCCCAGGA
AAGATAATAAGAATAATTAC

Downstream 100 bases:

>100_bases
GATTCCGTTATGCGTAAATTACTAAGACCTTTTTACGAACGTGATACCGTTCTGGTTGCAAAAGAACTTTTAGGTAAATA
TTTAGTTCATCATGATGGAT

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MGTLAQPSFINPNALAVLKKYFGFDSFRPPQEKIIEDVISGEDVLVLMPTGGGKSLCYQIPAIVRPGVGIVVSPLIALME
DQVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLLYIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFR
PEYACLGLLKTNFPDIPMIALTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGI
IYCGTRHTVEHLTAKLQELGFKARAYHAGLPHAVRREVQNLFRYDRIDIVVATIAFGMGIDKPNVRFVVHHDLPKSIEGY
YQETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLEEQRHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNC
DVCDNPPQTADATEDAQKFLSCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKD
YCLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKKKGKQNPSFKPESNPLFEKLRALRRQLADEENKPPFMIF
SDATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEALNEFSEVE

Sequences:

>Translated_608_residues
MGTLAQPSFINPNALAVLKKYFGFDSFRPPQEKIIEDVISGEDVLVLMPTGGGKSLCYQIPAIVRPGVGIVVSPLIALME
DQVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLLYIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFR
PEYACLGLLKTNFPDIPMIALTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGI
IYCGTRHTVEHLTAKLQELGFKARAYHAGLPHAVRREVQNLFRYDRIDIVVATIAFGMGIDKPNVRFVVHHDLPKSIEGY
YQETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLEEQRHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNC
DVCDNPPQTADATEDAQKFLSCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKD
YCLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKKKGKQNPSFKPESNPLFEKLRALRRQLADEENKPPFMIF
SDATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEALNEFSEVE
>Mature_607_residues
GTLAQPSFINPNALAVLKKYFGFDSFRPPQEKIIEDVISGEDVLVLMPTGGGKSLCYQIPAIVRPGVGIVVSPLIALMED
QVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLLYIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFRP
EYACLGLLKTNFPDIPMIALTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGII
YCGTRHTVEHLTAKLQELGFKARAYHAGLPHAVRREVQNLFRYDRIDIVVATIAFGMGIDKPNVRFVVHHDLPKSIEGYY
QETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLEEQRHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNCD
VCDNPPQTADATEDAQKFLSCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKDY
CLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKKKGKQNPSFKPESNPLFEKLRALRRQLADEENKPPFMIFS
DATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEALNEFSEVE

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=649, Percent_Identity=37.442218798151, Blast_Score=346, Evalue=4e-95,
Organism=Homo sapiens, GI110735439, Length=541, Percent_Identity=36.7837338262477, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI169218196, Length=509, Percent_Identity=37.328094302554, Blast_Score=323, Evalue=3e-88,
Organism=Homo sapiens, GI14591902, Length=535, Percent_Identity=36.2616822429907, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI14591904, Length=535, Percent_Identity=36.2616822429907, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI148612816, Length=422, Percent_Identity=41.4691943127962, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI51242947, Length=384, Percent_Identity=42.7083333333333, Blast_Score=281, Evalue=2e-75,
Organism=Homo sapiens, GI51242943, Length=384, Percent_Identity=42.7083333333333, Blast_Score=281, Evalue=2e-75,
Organism=Homo sapiens, GI284005309, Length=338, Percent_Identity=37.5739644970414, Blast_Score=209, Evalue=7e-54,
Organism=Homo sapiens, GI222352149, Length=372, Percent_Identity=23.6559139784946, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI7661920, Length=341, Percent_Identity=20.8211143695015, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI48994977, Length=598, Percent_Identity=49.1638795986622, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI87082221, Length=341, Percent_Identity=21.4076246334311, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787016, Length=341, Percent_Identity=22.2873900293255, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=668, Percent_Identity=33.8323353293413, Blast_Score=334, Evalue=8e-92,
Organism=Caenorhabditis elegans, GI32564293, Length=674, Percent_Identity=32.9376854599407, Blast_Score=328, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI71987997, Length=434, Percent_Identity=40.0921658986175, Blast_Score=311, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI71987993, Length=434, Percent_Identity=40.0921658986175, Blast_Score=311, Evalue=9e-85,
Organism=Caenorhabditis elegans, GI17552866, Length=410, Percent_Identity=36.0975609756098, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI17537549, Length=376, Percent_Identity=24.2021276595745, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995724, Length=353, Percent_Identity=22.0963172804533, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71987143, Length=355, Percent_Identity=21.9718309859155, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507121, Length=353, Percent_Identity=21.8130311614731, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565321, Length=130, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532548, Length=336, Percent_Identity=23.5119047619048, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533224, Length=341, Percent_Identity=21.7008797653959, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532546, Length=349, Percent_Identity=22.6361031518625, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=527, Percent_Identity=39.2789373814042, Blast_Score=355, Evalue=9e-99,
Organism=Saccharomyces cerevisiae, GI6324217, Length=340, Percent_Identity=25, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320224, Length=344, Percent_Identity=23.546511627907, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320041, Length=344, Percent_Identity=26.453488372093, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322912, Length=317, Percent_Identity=23.9747634069401, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322323, Length=317, Percent_Identity=23.9747634069401, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321856, Length=345, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323021, Length=373, Percent_Identity=22.2520107238606, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319714, Length=386, Percent_Identity=21.2435233160622, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321360, Length=331, Percent_Identity=22.9607250755287, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325138, Length=369, Percent_Identity=24.390243902439, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324778, Length=247, Percent_Identity=26.7206477732794, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646066, Length=626, Percent_Identity=34.9840255591054, Blast_Score=332, Evalue=6e-91,
Organism=Drosophila melanogaster, GI24664226, Length=438, Percent_Identity=36.5296803652968, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24664230, Length=438, Percent_Identity=36.5296803652968, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI62472181, Length=438, Percent_Identity=36.5296803652968, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI21358123, Length=404, Percent_Identity=35.3960396039604, Blast_Score=218, Evalue=8e-57,
Organism=Drosophila melanogaster, GI28574962, Length=343, Percent_Identity=24.198250728863, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355075, Length=385, Percent_Identity=21.8181818181818, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24583281, Length=333, Percent_Identity=24.6246246246246, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583279, Length=333, Percent_Identity=24.6246246246246, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24645031, Length=115, Percent_Identity=31.304347826087, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18857967, Length=350, Percent_Identity=23.4285714285714, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68848; Mature: 68717

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTLAQPSFINPNALAVLKKYFGFDSFRPPQEKIIEDVISGEDVLVLMPTGGGKSLCYQI
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHEEC
PAIVRPGVGIVVSPLIALMEDQVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLL
CHHHCCCCHHHHHHHHHHHHCCHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCCEEE
YIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFRPEYACLGLLKTNFPDIPMIA
EECHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEE
LTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGI
EEECCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCE
IYCGTRHTVEHLTAKLQELGFKARAYHAGLPHAVRREVQNLFRYDRIDIVVATIAFGMGI
EEECCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DKPNVRFVVHHDLPKSIEGYYQETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLEEQ
CCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCHH
RHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNCDVCDNPPQTADATEDAQKFL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
YCLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKKKGKQNPSFKPESNPLFEK
HHHHCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCHHHHH
LRALRRQLADEENKPPFMIFSDATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEA
HHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCCCCCHHEEECCCCCHHHHHHHHHHHHHH
LNEFSEVE
HHHHHCCC
>Mature Secondary Structure 
GTLAQPSFINPNALAVLKKYFGFDSFRPPQEKIIEDVISGEDVLVLMPTGGGKSLCYQI
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHEEC
PAIVRPGVGIVVSPLIALMEDQVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLL
CHHHCCCCHHHHHHHHHHHHCCHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCCEEE
YIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFRPEYACLGLLKTNFPDIPMIA
EECHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEE
LTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGI
EEECCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCE
IYCGTRHTVEHLTAKLQELGFKARAYHAGLPHAVRREVQNLFRYDRIDIVVATIAFGMGI
EEECCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DKPNVRFVVHHDLPKSIEGYYQETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLEEQ
CCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCHH
RHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNCDVCDNPPQTADATEDAQKFL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
YCLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKKKGKQNPSFKPESNPLFEK
HHHHCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCHHHHH
LRALRRQLADEENKPPFMIFSDATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEA
HHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCCCCCHHEEECCCCCHHHHHHHHHHHHHH
LNEFSEVE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]