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The map label for this gene is galE [H]

Identifier: 52787867

GI number: 52787867

Start: 4019066

End: 4020061

Strand: Direct

Name: galE [H]

Synonym: BLi04190

Alternate gene names: 52787867

Gene position: 4019066-4020061 (Clockwise)

Preceding gene: 52787866

Following gene: 52787872

Centisome position: 95.18

GC content: 50.9

Gene sequence:

>996_bases
ATGAGCGTACTAGTTGTCGGGGGAGCCGGTTATATCGGTTCCCACGCCGTTTACACGTTAATTGAGAAAAAAGAAAGAGT
CGTTGTTGTGGATTCCCTGGCAACAGGACACGCAGAAGCCGTTCACTCCGAAGCTGCGTTTTATAAAGGGGACATTCGCG
ACCGGCATTTTCTCAAGCAAGTATTTGAAAACGAGGACATTGAAGCCGTCATGCATTTCGCAGCATCTCCGATTTCCTCG
AAATCCAAAAACGTGTTTACTTCCTTTAACGAAAACATCACAGGAATGGAAACACTGCTTGACGTGATGAAAGAATACGA
TGTCGGCCGGATCGTTTTCGCGTCAAGCGCGGCCGTCTACGGCAGTCCAGAAGACCTCCCTGTCACGGAAGAAACCGAAC
CTGAGCCCGTTCACGCGCACGGCAAAGTCAAATGGATGATGGAGAAAATGCTGATGGAAGCGGAAAAAGCGTACGGGCTG
AAATATGTGATCCTCCGCTCCTTCAATGCGTGCGGCGCTCACCCATCCGCCATCATCGGCGAAGACCGGGGGAGCGAAAC
ACATCTCATTTCAAATGTTCTGCGAACCGCTCTCGGACACCTTCCTTTTGTTCACATAGATCAATCTGAAGACGGAACTG
GCGTCCGCGATTATGTTCATGTTCAAGATTTGGCAGAAGCACACGTGCTCGCCATCAATCACTTGCGGAAAGGCAAGGAT
AGCCGAATCTACAATCTCAGCTATGGCGAAAGCTACTCCGCTGAACAAATCATCCTTGCCGCCCAATATGTCACAGGCAT
TCCCCTCATCGCCGCAAAGCTGACAGAAACGGACATCGATTCACAAGCAACATTTGCCGCTTCTTCCTCCAGAGCCAGAA
AAGAATTAGGCTGGACCCCACAGCACAACAGCCTGATCGCGATCATCCGCGACGCCTGGAACTGGCACTCTGCGAATCCG
AATGGATATGCGTCGGAGAAGGTGAAGCAAGGGTGA

Upstream 100 bases:

>100_bases
GCTTTATATCATTGACGGAAAATACGGGTTTGAAGAACAGCGGCGGGCGCGAGCTCCCCAGCGCCATATTATGTAGAAAG
ATCCAAAAGGAGGGATTCCG

Downstream 100 bases:

>100_bases
AAATGAACTGCACCCCTATCGTTAGGCAGCGTCTAACTATGGAGGTGCGTTTTTTTCTCCATCGGCTTTGCGGTAGTTGG
TGATCATCGGCAGGCCATTG

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSVLVVGGAGYIGSHAVYTLIEKKERVVVVDSLATGHAEAVHSEAAFYKGDIRDRHFLKQVFENEDIEAVMHFAASPISS
KSKNVFTSFNENITGMETLLDVMKEYDVGRIVFASSAAVYGSPEDLPVTEETEPEPVHAHGKVKWMMEKMLMEAEKAYGL
KYVILRSFNACGAHPSAIIGEDRGSETHLISNVLRTALGHLPFVHIDQSEDGTGVRDYVHVQDLAEAHVLAINHLRKGKD
SRIYNLSYGESYSAEQIILAAQYVTGIPLIAAKLTETDIDSQATFAASSSRARKELGWTPQHNSLIAIIRDAWNWHSANP
NGYASEKVKQG

Sequences:

>Translated_331_residues
MSVLVVGGAGYIGSHAVYTLIEKKERVVVVDSLATGHAEAVHSEAAFYKGDIRDRHFLKQVFENEDIEAVMHFAASPISS
KSKNVFTSFNENITGMETLLDVMKEYDVGRIVFASSAAVYGSPEDLPVTEETEPEPVHAHGKVKWMMEKMLMEAEKAYGL
KYVILRSFNACGAHPSAIIGEDRGSETHLISNVLRTALGHLPFVHIDQSEDGTGVRDYVHVQDLAEAHVLAINHLRKGKD
SRIYNLSYGESYSAEQIILAAQYVTGIPLIAAKLTETDIDSQATFAASSSRARKELGWTPQHNSLIAIIRDAWNWHSANP
NGYASEKVKQG
>Mature_330_residues
SVLVVGGAGYIGSHAVYTLIEKKERVVVVDSLATGHAEAVHSEAAFYKGDIRDRHFLKQVFENEDIEAVMHFAASPISSK
SKNVFTSFNENITGMETLLDVMKEYDVGRIVFASSAAVYGSPEDLPVTEETEPEPVHAHGKVKWMMEKMLMEAEKAYGLK
YVILRSFNACGAHPSAIIGEDRGSETHLISNVLRTALGHLPFVHIDQSEDGTGVRDYVHVQDLAEAHVLAINHLRKGKDS
RIYNLSYGESYSAEQIILAAQYVTGIPLIAAKLTETDIDSQATFAASSSRARKELGWTPQHNSLIAIIRDAWNWHSANPN
GYASEKVKQG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=350, Percent_Identity=35.7142857142857, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI56118217, Length=350, Percent_Identity=35.7142857142857, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI189083684, Length=350, Percent_Identity=35.7142857142857, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI7657641, Length=320, Percent_Identity=26.25, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI116268111, Length=369, Percent_Identity=24.9322493224932, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786974, Length=340, Percent_Identity=32.3529411764706, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI48994969, Length=364, Percent_Identity=28.2967032967033, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788353, Length=359, Percent_Identity=25.6267409470752, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=359, Percent_Identity=33.983286908078, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71982038, Length=361, Percent_Identity=33.7950138504155, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17568069, Length=339, Percent_Identity=26.5486725663717, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=34.3023255813954, Blast_Score=180, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6321437, Length=250, Percent_Identity=24.8, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19923002, Length=354, Percent_Identity=35.8757062146893, Blast_Score=194, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36427; Mature: 36296

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVVGGAGYIGSHAVYTLIEKKERVVVVDSLATGHAEAVHSEAAFYKGDIRDRHFLKQ
CEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHH
VFENEDIEAVMHFAASPISSKSKNVFTSFNENITGMETLLDVMKEYDVGRIVFASSAAVY
HHCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCEEEC
GSPEDLPVTEETEPEPVHAHGKVKWMMEKMLMEAEKAYGLKYVILRSFNACGAHPSAIIG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEE
EDRGSETHLISNVLRTALGHLPFVHIDQSEDGTGVRDYVHVQDLAEAHVLAINHLRKGKD
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SRIYNLSYGESYSAEQIILAAQYVTGIPLIAAKLTETDIDSQATFAASSSRARKELGWTP
CEEEEECCCCCCCCCCEEEEHHHHHCCHHHHHHHHHCCCCCCCEEHHCHHHHHHHCCCCC
QHNSLIAIIRDAWNWHSANPNGYASEKVKQG
CCCCEEEEEECCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
SVLVVGGAGYIGSHAVYTLIEKKERVVVVDSLATGHAEAVHSEAAFYKGDIRDRHFLKQ
EEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHH
VFENEDIEAVMHFAASPISSKSKNVFTSFNENITGMETLLDVMKEYDVGRIVFASSAAVY
HHCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCEEEC
GSPEDLPVTEETEPEPVHAHGKVKWMMEKMLMEAEKAYGLKYVILRSFNACGAHPSAIIG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEE
EDRGSETHLISNVLRTALGHLPFVHIDQSEDGTGVRDYVHVQDLAEAHVLAINHLRKGKD
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SRIYNLSYGESYSAEQIILAAQYVTGIPLIAAKLTETDIDSQATFAASSSRARKELGWTP
CEEEEECCCCCCCCCCEEEEHHHHHCCHHHHHHHHHCCCCCCCEEHHCHHHHHHHCCCCC
QHNSLIAIIRDAWNWHSANPNGYASEKVKQG
CCCCEEEEEECCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]