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The map label for this gene is ykcC [H]

Identifier: 52787866

GI number: 52787866

Start: 4018043

End: 4019041

Strand: Direct

Name: ykcC [H]

Synonym: BLi04189

Alternate gene names: 52787866

Gene position: 4018043-4019041 (Clockwise)

Preceding gene: 52787865

Following gene: 52787867

Centisome position: 95.15

GC content: 48.85

Gene sequence:

>999_bases
ATGAAAGGAAAGGTGATGAATATGCAGAAACAAGTCACATTTTCAATCGTAGTACCTGTCTACAACGAAGCGGAAGTGCT
TCAAAGCACCTATGACCGATTAAAAACCGTCATGGACTCGACAGGCGATCCCTATGAACTGATTTTTGTAAACGATGGTT
CAAGCGATGACAGCATTCACACGCTGAAGTCGCTTGCTCAGTCAGACCAGGCAGTAAAATGCATCAATTTCTCAAGAAAC
TTCGGTCATCAGATCGCGATTACGGCCGGCACAGACTATGCTGCCGGCGAGGCGATCGTTGTGATCGACGCCGATTTGCA
GGATCCTCCTGAATTGATTTTGGAAATGGCGGAAAAATGGCGCCAAGGCTTTGACGTTGTATACGCCGTCCGCACAAAGC
GAGAAGGAGAAACATTTTTCAAAAAGCAAACGGCCGCCATGTTCTACCGGATTTTAAGAAAACTTACAGACGTTGATATC
CCGGTGGATACAGGAGACTTCCGGCTCATGGACCGGAAGGTGGTCAATGAAATGAACAAGCTGAAAGAAAAAAACCCGTT
CGTCCGCGGTCTTGTCAGCTGGCTCGGGTTCAAGCAGACAGCCGTCTATTACGAGCGCCACGAACGGCTTGCAGGGGAAA
CGAAGTACCCGCTGAAAAAAATGCTGAAGCTCTCGCTCGACGGCATCACTTCATTTTCCTTTCAGCCGCTGAAACTGGCA
AGCTACTCAGGAATCGTGCTGTCAGCGATCGGCTTTATATACGCCTTCATCGTCGTCTGCATGAAGCTGTTTACGACAAG
CACCATTACAGGATGGTCGTCGATGATCATTCTGCAATGCTTGTTCAGCGGATTTATCCTGATCATCCTCGGGGCAATCG
GCGAATACATCGGCCGCATTTATGACGAAGTGAAAGACAGGCCGCTTTATATCATTGACGGAAAATACGGGTTTGAAGAA
CAGCGGCGGGCGCGAGCTCCCCAGCGCCATATTATGTAG

Upstream 100 bases:

>100_bases
CAGAAATTTCAAAAAGCGAATACAGCAGCTCTTCTTCTGATGATTCACAGTCAGGCGGACCTGGCGGAAATCAAACGCTT
TATAAAGTGGAGCTGGATTG

Downstream 100 bases:

>100_bases
AAAGATCCAAAAGGAGGGATTCCGATGAGCGTACTAGTTGTCGGGGGAGCCGGTTATATCGGTTCCCACGCCGTTTACAC
GTTAATTGAGAAAAAAGAAA

Product: YkcC

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKGKVMNMQKQVTFSIVVPVYNEAEVLQSTYDRLKTVMDSTGDPYELIFVNDGSSDDSIHTLKSLAQSDQAVKCINFSRN
FGHQIAITAGTDYAAGEAIVVIDADLQDPPELILEMAEKWRQGFDVVYAVRTKREGETFFKKQTAAMFYRILRKLTDVDI
PVDTGDFRLMDRKVVNEMNKLKEKNPFVRGLVSWLGFKQTAVYYERHERLAGETKYPLKKMLKLSLDGITSFSFQPLKLA
SYSGIVLSAIGFIYAFIVVCMKLFTTSTITGWSSMIILQCLFSGFILIILGAIGEYIGRIYDEVKDRPLYIIDGKYGFEE
QRRARAPQRHIM

Sequences:

>Translated_332_residues
MKGKVMNMQKQVTFSIVVPVYNEAEVLQSTYDRLKTVMDSTGDPYELIFVNDGSSDDSIHTLKSLAQSDQAVKCINFSRN
FGHQIAITAGTDYAAGEAIVVIDADLQDPPELILEMAEKWRQGFDVVYAVRTKREGETFFKKQTAAMFYRILRKLTDVDI
PVDTGDFRLMDRKVVNEMNKLKEKNPFVRGLVSWLGFKQTAVYYERHERLAGETKYPLKKMLKLSLDGITSFSFQPLKLA
SYSGIVLSAIGFIYAFIVVCMKLFTTSTITGWSSMIILQCLFSGFILIILGAIGEYIGRIYDEVKDRPLYIIDGKYGFEE
QRRARAPQRHIM
>Mature_332_residues
MKGKVMNMQKQVTFSIVVPVYNEAEVLQSTYDRLKTVMDSTGDPYELIFVNDGSSDDSIHTLKSLAQSDQAVKCINFSRN
FGHQIAITAGTDYAAGEAIVVIDADLQDPPELILEMAEKWRQGFDVVYAVRTKREGETFFKKQTAAMFYRILRKLTDVDI
PVDTGDFRLMDRKVVNEMNKLKEKNPFVRGLVSWLGFKQTAVYYERHERLAGETKYPLKKMLKLSLDGITSFSFQPLKLA
SYSGIVLSAIGFIYAFIVVCMKLFTTSTITGWSSMIILQCLFSGFILIILGAIGEYIGRIYDEVKDRPLYIIDGKYGFEE
QRRARAPQRHIM

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=298, Percent_Identity=40.6040268456376, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1788588, Length=305, Percent_Identity=32.7868852459016, Blast_Score=174, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 37785; Mature: 37785

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKVMNMQKQVTFSIVVPVYNEAEVLQSTYDRLKTVMDSTGDPYELIFVNDGSSDDSIH
CCCCCCCHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHH
TLKSLAQSDQAVKCINFSRNFGHQIAITAGTDYAAGEAIVVIDADLQDPPELILEMAEKW
HHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
RQGFDVVYAVRTKREGETFFKKQTAAMFYRILRKLTDVDIPVDTGDFRLMDRKVVNEMNK
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LKEKNPFVRGLVSWLGFKQTAVYYERHERLAGETKYPLKKMLKLSLDGITSFSFQPLKLA
HHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEECC
SYSGIVLSAIGFIYAFIVVCMKLFTTSTITGWSSMIILQCLFSGFILIILGAIGEYIGRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDEVKDRPLYIIDGKYGFEEQRRARAPQRHIM
HHHHCCCCEEEECCCCCCHHHHHHCCCHHCCC
>Mature Secondary Structure
MKGKVMNMQKQVTFSIVVPVYNEAEVLQSTYDRLKTVMDSTGDPYELIFVNDGSSDDSIH
CCCCCCCHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHH
TLKSLAQSDQAVKCINFSRNFGHQIAITAGTDYAAGEAIVVIDADLQDPPELILEMAEKW
HHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
RQGFDVVYAVRTKREGETFFKKQTAAMFYRILRKLTDVDIPVDTGDFRLMDRKVVNEMNK
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LKEKNPFVRGLVSWLGFKQTAVYYERHERLAGETKYPLKKMLKLSLDGITSFSFQPLKLA
HHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEECC
SYSGIVLSAIGFIYAFIVVCMKLFTTSTITGWSSMIILQCLFSGFILIILGAIGEYIGRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDEVKDRPLYIIDGKYGFEEQRRARAPQRHIM
HHHHCCCCEEEECCCCCCHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]