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The map label for this gene is yvrG [H]

Identifier: 52787208

GI number: 52787208

Start: 3358479

End: 3360236

Strand: Reverse

Name: yvrG [H]

Synonym: BLi03517

Alternate gene names: 52787208

Gene position: 3360236-3358479 (Counterclockwise)

Preceding gene: 52787209

Following gene: 52787207

Centisome position: 79.58

GC content: 45.56

Gene sequence:

>1758_bases
ATGAAGCTCAGAGGAAAGCTCGTTCTCCACTTTGTCAGTCAGATTTTTTTGATTCTCGGTCTTGTTCTCGCGACCTTGCT
GTTATCCTTCATTTTTTTCGCTCTCCGATTAAGCGAGAGCGAAGCGGATACAGGCTTGGCAAAAGCCACTTCAGACACGT
TTGAAAGCTGGGTCAGCGTGGATGACAATAACAATTGGCAGATCGAAGATATCTTGAAATCGGCTATCGACAAACAGGGA
GGCTGGCTTCAAATATTAGACGGCAAGGAGAAAACCGTTTATTCCTACCGTCTTCCTGCGGAAATTCAGAGGCAGTACCA
CAGGGAAGACCTGGTATCCGTTTTTGATAAAAAAAGAATTAAAAAATATCAAGTCAACTTCTGGTCTGCCAATTTCAATG
GTGAAGACTACGTGATTTTATTCGGATGGGAGTCGAAAAGCGATACGATCCTGTCCTATTTGGAAAAAGAAGAGAAGGAT
ATGGCAGACCTTTCTTCCTATAAAAAAAGCACGCTTGATTTCATTAAGAAAAACAAAGGGTCCGTCTATTTGTTCAGCGA
AAAAGGGAAAATGCTGGACTCGATCTACCAGGACATAGATTACAGCCAGGGAATCAATGAGCTGGAGCTTTTAAAATACG
GATCAAAGCCATGGAACTACGAGCACGAGTTTTCATACAGGCGATTAAGCGCGACAGAATGGCTGATCGCCGCTACGCCG
AACCCGATTTTTAATCCGGATCATGAGTTCAACAGGACGATGATCGGGCTCGCTTTAAAAATCGTTCTCATCGTGATCGG
CGTTCTGATCTTATTGATGTCTTCTATGACCATTTGGTATTCTTTCAGATTCGGCATGCCGATCATCCATACGATTAAAT
GGATCGTCAACCTTTCAAAAGGGCGATTTGAAGAACCGAGAAACCGGAAAGGCCGCCCGCGAAGCCGGAACAAAAAAGGG
AAGCGAAAACAGCCGTACCGGCTGTTCACAGAAGTGTTTGAATCGATGGAGCAGCTGACGGAAACGCTGAAAAAAGACGA
GCAAAACCGCAAGAAAATCCAAACGACCCGGGAGGAATGGATCGCAGGGCTCTCCCATGACTTAAAAACGCCGCTCAGCA
CGATTTACGGCTACAGCATGATGCTGGAGTCTCCAAACTATGAGTGGTCAAAAGAGGAAATCCGCGAAATCGGCCAGGCG
ATGAAAGAAAAGTCGGACTACATGTCACAGCTAATCGAAGACTTGAACTTGACGTACAGGCTGAAAAACGACGCTTTGCC
GATTAAACGCCAGACAGTGAGGCTCGTGCCGTTTTTAAAGAGCTTCGTTGAGGAGTTTAAGCGCCATTCATTTTCAGAAG
GGTACAACGTGTCTTTTGAATACAAGCAAGTAGATACCGAGTTTGCGATAGACAGGGGCTGGTTCCGAAGAGTCTTGGAA
AACCTCCTCGCCAACGCCGTCAAGCATAACAAAAAAGGCACTGACATCAAGGTGATCCTTGAAGAATCCAAGCAATATAT
TATTCTTAAAATTCAAGACAACGGAAGAGGCATGGACTCTGAAACCGTCTCAAATTTATTCAACCGCTACTACAGGGGAA
CGCATACAAAAGATGCGACAGAAGGAAGCGGTCTCGGCCTTGCTATTTCTTTGGAACTTGTCCACCTGCACGACGGCTGC
ATCGCAGTTGACAGCCGGACAGGCCGAGGGACGGAAATTACGATGGAATTTAAGAAAAACCCTAAAGCCGCCAAATAA

Upstream 100 bases:

>100_bases
AGAAAATCGAAAAAGACCCGAGCAGCCCCGAATATATTGTCACGATTCGCGGCCTTGGATATAAGTTCGTTCCCAATCCT
GCACGAAAAGAGAGCGAAGG

Downstream 100 bases:

>100_bases
GCGGTATGAAAAAGAAGAAGCCAAAGGTTATTGCCTTTAGGCTTCTTTTATGTTGAGAAAATAATGGAAAAGAAGGCGCG
GTTAGTATAAAATAAGATTA

Product: YvrG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MKLRGKLVLHFVSQIFLILGLVLATLLLSFIFFALRLSESEADTGLAKATSDTFESWVSVDDNNNWQIEDILKSAIDKQG
GWLQILDGKEKTVYSYRLPAEIQRQYHREDLVSVFDKKRIKKYQVNFWSANFNGEDYVILFGWESKSDTILSYLEKEEKD
MADLSSYKKSTLDFIKKNKGSVYLFSEKGKMLDSIYQDIDYSQGINELELLKYGSKPWNYEHEFSYRRLSATEWLIAATP
NPIFNPDHEFNRTMIGLALKIVLIVIGVLILLMSSMTIWYSFRFGMPIIHTIKWIVNLSKGRFEEPRNRKGRPRSRNKKG
KRKQPYRLFTEVFESMEQLTETLKKDEQNRKKIQTTREEWIAGLSHDLKTPLSTIYGYSMMLESPNYEWSKEEIREIGQA
MKEKSDYMSQLIEDLNLTYRLKNDALPIKRQTVRLVPFLKSFVEEFKRHSFSEGYNVSFEYKQVDTEFAIDRGWFRRVLE
NLLANAVKHNKKGTDIKVILEESKQYIILKIQDNGRGMDSETVSNLFNRYYRGTHTKDATEGSGLGLAISLELVHLHDGC
IAVDSRTGRGTEITMEFKKNPKAAK

Sequences:

>Translated_585_residues
MKLRGKLVLHFVSQIFLILGLVLATLLLSFIFFALRLSESEADTGLAKATSDTFESWVSVDDNNNWQIEDILKSAIDKQG
GWLQILDGKEKTVYSYRLPAEIQRQYHREDLVSVFDKKRIKKYQVNFWSANFNGEDYVILFGWESKSDTILSYLEKEEKD
MADLSSYKKSTLDFIKKNKGSVYLFSEKGKMLDSIYQDIDYSQGINELELLKYGSKPWNYEHEFSYRRLSATEWLIAATP
NPIFNPDHEFNRTMIGLALKIVLIVIGVLILLMSSMTIWYSFRFGMPIIHTIKWIVNLSKGRFEEPRNRKGRPRSRNKKG
KRKQPYRLFTEVFESMEQLTETLKKDEQNRKKIQTTREEWIAGLSHDLKTPLSTIYGYSMMLESPNYEWSKEEIREIGQA
MKEKSDYMSQLIEDLNLTYRLKNDALPIKRQTVRLVPFLKSFVEEFKRHSFSEGYNVSFEYKQVDTEFAIDRGWFRRVLE
NLLANAVKHNKKGTDIKVILEESKQYIILKIQDNGRGMDSETVSNLFNRYYRGTHTKDATEGSGLGLAISLELVHLHDGC
IAVDSRTGRGTEITMEFKKNPKAAK
>Mature_585_residues
MKLRGKLVLHFVSQIFLILGLVLATLLLSFIFFALRLSESEADTGLAKATSDTFESWVSVDDNNNWQIEDILKSAIDKQG
GWLQILDGKEKTVYSYRLPAEIQRQYHREDLVSVFDKKRIKKYQVNFWSANFNGEDYVILFGWESKSDTILSYLEKEEKD
MADLSSYKKSTLDFIKKNKGSVYLFSEKGKMLDSIYQDIDYSQGINELELLKYGSKPWNYEHEFSYRRLSATEWLIAATP
NPIFNPDHEFNRTMIGLALKIVLIVIGVLILLMSSMTIWYSFRFGMPIIHTIKWIVNLSKGRFEEPRNRKGRPRSRNKKG
KRKQPYRLFTEVFESMEQLTETLKKDEQNRKKIQTTREEWIAGLSHDLKTPLSTIYGYSMMLESPNYEWSKEEIREIGQA
MKEKSDYMSQLIEDLNLTYRLKNDALPIKRQTVRLVPFLKSFVEEFKRHSFSEGYNVSFEYKQVDTEFAIDRGWFRRVLE
NLLANAVKHNKKGTDIKVILEESKQYIILKIQDNGRGMDSETVSNLFNRYYRGTHTKDATEGSGLGLAISLELVHLHDGC
IAVDSRTGRGTEITMEFKKNPKAAK

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=266, Percent_Identity=25.9398496240602, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=244, Percent_Identity=30.7377049180328, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=27.2373540856031, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=24.0663900414938, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=25.8333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=24.0506329113924, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=25.8196721311475, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788549, Length=290, Percent_Identity=24.4827586206897, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=27.0531400966184, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=23.2365145228216, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=23.175965665236, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68166; Mature: 68166

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRGKLVLHFVSQIFLILGLVLATLLLSFIFFALRLSESEADTGLAKATSDTFESWVSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEC
DDNNNWQIEDILKSAIDKQGGWLQILDGKEKTVYSYRLPAEIQRQYHREDLVSVFDKKRI
CCCCCEEHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
KKYQVNFWSANFNGEDYVILFGWESKSDTILSYLEKEEKDMADLSSYKKSTLDFIKKNKG
HEEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVYLFSEKGKMLDSIYQDIDYSQGINELELLKYGSKPWNYEHEFSYRRLSATEWLIAATP
CEEEECCCCHHHHHHHHHCCHHCCCCHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEECC
NPIFNPDHEFNRTMIGLALKIVLIVIGVLILLMSSMTIWYSFRFGMPIIHTIKWIVNLSK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCC
GRFEEPRNRKGRPRSRNKKGKRKQPYRLFTEVFESMEQLTETLKKDEQNRKKIQTTREEW
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGLSHDLKTPLSTIYGYSMMLESPNYEWSKEEIREIGQAMKEKSDYMSQLIEDLNLTYR
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LKNDALPIKRQTVRLVPFLKSFVEEFKRHSFSEGYNVSFEYKQVDTEFAIDRGWFRRVLE
ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
NLLANAVKHNKKGTDIKVILEESKQYIILKIQDNGRGMDSETVSNLFNRYYRGTHTKDAT
HHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
EGSGLGLAISLELVHLHDGCIAVDSRTGRGTEITMEFKKNPKAAK
CCCCCEEEEEEEEEEEECCEEEEECCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MKLRGKLVLHFVSQIFLILGLVLATLLLSFIFFALRLSESEADTGLAKATSDTFESWVSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEC
DDNNNWQIEDILKSAIDKQGGWLQILDGKEKTVYSYRLPAEIQRQYHREDLVSVFDKKRI
CCCCCEEHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
KKYQVNFWSANFNGEDYVILFGWESKSDTILSYLEKEEKDMADLSSYKKSTLDFIKKNKG
HEEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVYLFSEKGKMLDSIYQDIDYSQGINELELLKYGSKPWNYEHEFSYRRLSATEWLIAATP
CEEEECCCCHHHHHHHHHCCHHCCCCHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEECC
NPIFNPDHEFNRTMIGLALKIVLIVIGVLILLMSSMTIWYSFRFGMPIIHTIKWIVNLSK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCC
GRFEEPRNRKGRPRSRNKKGKRKQPYRLFTEVFESMEQLTETLKKDEQNRKKIQTTREEW
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGLSHDLKTPLSTIYGYSMMLESPNYEWSKEEIREIGQAMKEKSDYMSQLIEDLNLTYR
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LKNDALPIKRQTVRLVPFLKSFVEEFKRHSFSEGYNVSFEYKQVDTEFAIDRGWFRRVLE
ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
NLLANAVKHNKKGTDIKVILEESKQYIILKIQDNGRGMDSETVSNLFNRYYRGTHTKDAT
HHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
EGSGLGLAISLELVHLHDGCIAVDSRTGRGTEITMEFKKNPKAAK
CCCCCEEEEEEEEEEEECCEEEEECCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]