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The map label for this gene is uxaC

Identifier: 52787207

GI number: 52787207

Start: 3356881

End: 3358302

Strand: Reverse

Name: uxaC

Synonym: BLi03516

Alternate gene names: 52787207

Gene position: 3358302-3356881 (Counterclockwise)

Preceding gene: 52787208

Following gene: 52787206

Centisome position: 79.53

GC content: 47.54

Gene sequence:

>1422_bases
GTGAAGCCGTTTTTGAATGACGATTTTCTTTTAACGAATGAAACGTCGAAAGTGTTGTACCATCAGTATGCAAAAGGAAT
GCCGATCATCGACTACCACTGCCACTTGAGCCCGAAGGAGATTTACGAAAACAAAACGTTTAAAAACCTGACCGAAGTAT
GGCTCTACGGTGATCACTACAAGTGGAGAGCAATGAGGGCCAATGGAATATCCGAAGAGTTTATTACAGGAGATGCGTCA
GACGAGGAGAAATTCAGCGCCTGGGCAAGAACGGTTCCGATGACGATTGGAAACCCGCTCTATCATTGGACCCATTTGGA
GCTGAGGAGGTTTTTCGGCATCGATGACCGGCTTGATGAAAAGAGCGCGCCGCATATTTGGGAGCGGGTTAACGAACAGC
TGGCCGGAGGAGGGTTCGGCGCCAGAGACTTGATTGAAAAATCAAACGTTGAAACGGTTGTCACGACAGATGACCCCACA
GACAGTCTTGAATATCATGTAAAGCTGAAAGATGAAGACTTTAATGTAAGCGTTTTACCTGGATTTAGGCCAGACAAGGC
GATGGAAATCAATCAAGAGGGTTTTGCCGCCTGGGTGAGAAAGCTTGAAACAGCTAGCGGTATGAAGATAGCGAATTATG
ACGATTTTTTGAAAGCGCTTAAAAACAGAATTGACTTTTTCCATGAAGCAGGCGGACGGATATCGGATCATGCCATCAAT
CAAATGATGTACACGGAAACAGATGAGAGCGAAGTGCGCCCGATTTTTGCAAAGGTGATGAACGGGGAAAGCGCCTCGCC
TGAGGAAGAGTGCAAATTCAAATCCTTGACCTTGCACTTTTTGGGAACATGCTATGCGGAGAAGGGCTGGGCGATGCAGC
TCCACATTAACGCCCTCCGCAACAACAGCAGCAAAATGTACCGGAAGCTCGGGCCTGATACGGGATATGATGCGATTAAT
GATCAGGATATCGCAAAGCCTTTGTGCAGCTTTCTCGATTCTCTTGATCGAAAAGATGCGCTGCCAAAAACGATCTTGTA
TTCTTTAAACCCGCGGGACAATGTCGTGATTTCAAGCCTTTGCGGAAGCTTCCAGGACGGCCGGATACCGGGGAAAATCC
AGCACGGTACCGCCTGGTGGTTCAACGATACGAAAGACGGCATGCTCGAACAAATGAAATCGCTTGCCAACATCGGTCTA
TTGAGCCGTTTTATCGGTATGCTGACTGATTCGCGCAGCTTTCTTTCCTACACAAGACACGAATATTTCAGGCGCCTGCT
CTGCGATGTTATCGGCACATGGGTTGAGAACGGCGAAGCGCCGGATGATATCGAACTGCTGGGCCGGATCGTAAAAGGGA
TCTGCTACGAAAATGCAAAACACTATTTCCAGTTTGAAGTGAAAGATCGTTTGAAAGCTTAG

Upstream 100 bases:

>100_bases
CGCGGTTAGTATAAAATAAGATTAAATGTTAACGTTCACATTATGCTGCAGATGGTTTTGTTAACGTTAACATTTATAAA
TAAAGAAAGGTGGAGATTCT

Downstream 100 bases:

>100_bases
ATTCACAAATTGGCTAGCAGAGGAGCTGCTTTTTCATGGAAATATCGACGAACAAACAAACCGAAACAGTCGCCGTCACT
CAAGAGAAATTAAGTTTAAA

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MKPFLNDDFLLTNETSKVLYHQYAKGMPIIDYHCHLSPKEIYENKTFKNLTEVWLYGDHYKWRAMRANGISEEFITGDAS
DEEKFSAWARTVPMTIGNPLYHWTHLELRRFFGIDDRLDEKSAPHIWERVNEQLAGGGFGARDLIEKSNVETVVTTDDPT
DSLEYHVKLKDEDFNVSVLPGFRPDKAMEINQEGFAAWVRKLETASGMKIANYDDFLKALKNRIDFFHEAGGRISDHAIN
QMMYTETDESEVRPIFAKVMNGESASPEEECKFKSLTLHFLGTCYAEKGWAMQLHINALRNNSSKMYRKLGPDTGYDAIN
DQDIAKPLCSFLDSLDRKDALPKTILYSLNPRDNVVISSLCGSFQDGRIPGKIQHGTAWWFNDTKDGMLEQMKSLANIGL
LSRFIGMLTDSRSFLSYTRHEYFRRLLCDVIGTWVENGEAPDDIELLGRIVKGICYENAKHYFQFEVKDRLKA

Sequences:

>Translated_473_residues
MKPFLNDDFLLTNETSKVLYHQYAKGMPIIDYHCHLSPKEIYENKTFKNLTEVWLYGDHYKWRAMRANGISEEFITGDAS
DEEKFSAWARTVPMTIGNPLYHWTHLELRRFFGIDDRLDEKSAPHIWERVNEQLAGGGFGARDLIEKSNVETVVTTDDPT
DSLEYHVKLKDEDFNVSVLPGFRPDKAMEINQEGFAAWVRKLETASGMKIANYDDFLKALKNRIDFFHEAGGRISDHAIN
QMMYTETDESEVRPIFAKVMNGESASPEEECKFKSLTLHFLGTCYAEKGWAMQLHINALRNNSSKMYRKLGPDTGYDAIN
DQDIAKPLCSFLDSLDRKDALPKTILYSLNPRDNVVISSLCGSFQDGRIPGKIQHGTAWWFNDTKDGMLEQMKSLANIGL
LSRFIGMLTDSRSFLSYTRHEYFRRLLCDVIGTWVENGEAPDDIELLGRIVKGICYENAKHYFQFEVKDRLKA
>Mature_473_residues
MKPFLNDDFLLTNETSKVLYHQYAKGMPIIDYHCHLSPKEIYENKTFKNLTEVWLYGDHYKWRAMRANGISEEFITGDAS
DEEKFSAWARTVPMTIGNPLYHWTHLELRRFFGIDDRLDEKSAPHIWERVNEQLAGGGFGARDLIEKSNVETVVTTDDPT
DSLEYHVKLKDEDFNVSVLPGFRPDKAMEINQEGFAAWVRKLETASGMKIANYDDFLKALKNRIDFFHEAGGRISDHAIN
QMMYTETDESEVRPIFAKVMNGESASPEEECKFKSLTLHFLGTCYAEKGWAMQLHINALRNNSSKMYRKLGPDTGYDAIN
DQDIAKPLCSFLDSLDRKDALPKTILYSLNPRDNVVISSLCGSFQDGRIPGKIQHGTAWWFNDTKDGMLEQMKSLANIGL
LSRFIGMLTDSRSFLSYTRHEYFRRLLCDVIGTWVENGEAPDDIELLGRIVKGICYENAKHYFQFEVKDRLKA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=469, Percent_Identity=54.7974413646055, Blast_Score=541, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_BACLD (Q65F21)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080611.1
- RefSeq:   YP_093036.1
- ProteinModelPortal:   Q65F21
- SMR:   Q65F21
- STRING:   Q65F21
- EnsemblBacteria:   EBBACT00000057320
- EnsemblBacteria:   EBBACT00000062487
- GeneID:   3029362
- GeneID:   3100105
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03516
- KEGG:   bli:BL00708
- NMPDR:   fig|279010.5.peg.1875
- eggNOG:   COG1904
- GeneTree:   EBGT00050000002347
- HOGENOM:   HBG297087
- OMA:   AWAKTVP
- ProtClustDB:   PRK02925
- BioCyc:   BLIC279010-1:BLI03516-MONOMER
- BioCyc:   BLIC279010:BL00708-MONOMER
- HAMAP:   MF_00675
- InterPro:   IPR003766
- InterPro:   IPR023177
- Gene3D:   G3DSA:1.10.2020.10

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 54379; Mature: 54379

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFLNDDFLLTNETSKVLYHQYAKGMPIIDYHCHLSPKEIYENKTFKNLTEVWLYGDHY
CCCCCCCCEEEECCHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCHHHHHHHHEEECCCE
KWRAMRANGISEEFITGDASDEEKFSAWARTVPMTIGNPLYHWTHLELRRFFGIDDRLDE
EEEEEECCCCCHHHCCCCCCCHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHCCCCCCCCC
KSAPHIWERVNEQLAGGGFGARDLIEKSNVETVVTTDDPTDSLEYHVKLKDEDFNVSVLP
CCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCCCCCCEEEEEEEECCCCEEEECC
GFRPDKAMEINQEGFAAWVRKLETASGMKIANYDDFLKALKNRIDFFHEAGGRISDHAIN
CCCCCCCCEECHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QMMYTETDESEVRPIFAKVMNGESASPEEECKFKSLTLHFLGTCYAEKGWAMQLHINALR
HHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHH
NNSSKMYRKLGPDTGYDAINDQDIAKPLCSFLDSLDRKDALPKTILYSLNPRDNVVISSL
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHHH
CGSFQDGRIPGKIQHGTAWWFNDTKDGMLEQMKSLANIGLLSRFIGMLTDSRSFLSYTRH
HCCCCCCCCCCEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EYFRRLLCDVIGTWVENGEAPDDIELLGRIVKGICYENAKHYFQFEVKDRLKA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHEEEEEHHHHCCC
>Mature Secondary Structure
MKPFLNDDFLLTNETSKVLYHQYAKGMPIIDYHCHLSPKEIYENKTFKNLTEVWLYGDHY
CCCCCCCCEEEECCHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCHHHHHHHHEEECCCE
KWRAMRANGISEEFITGDASDEEKFSAWARTVPMTIGNPLYHWTHLELRRFFGIDDRLDE
EEEEEECCCCCHHHCCCCCCCHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHCCCCCCCCC
KSAPHIWERVNEQLAGGGFGARDLIEKSNVETVVTTDDPTDSLEYHVKLKDEDFNVSVLP
CCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCCCCCCEEEEEEEECCCCEEEECC
GFRPDKAMEINQEGFAAWVRKLETASGMKIANYDDFLKALKNRIDFFHEAGGRISDHAIN
CCCCCCCCEECHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QMMYTETDESEVRPIFAKVMNGESASPEEECKFKSLTLHFLGTCYAEKGWAMQLHINALR
HHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHH
NNSSKMYRKLGPDTGYDAINDQDIAKPLCSFLDSLDRKDALPKTILYSLNPRDNVVISSL
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHHH
CGSFQDGRIPGKIQHGTAWWFNDTKDGMLEQMKSLANIGLLSRFIGMLTDSRSFLSYTRH
HCCCCCCCCCCEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EYFRRLLCDVIGTWVENGEAPDDIELLGRIVKGICYENAKHYFQFEVKDRLKA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA