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The map label for this gene is exuR [H]

Identifier: 52787205

GI number: 52787205

Start: 3354379

End: 3355377

Strand: Reverse

Name: exuR [H]

Synonym: BLi03514

Alternate gene names: 52787205

Gene position: 3355377-3354379 (Counterclockwise)

Preceding gene: 52787206

Following gene: 52787204

Centisome position: 79.46

GC content: 47.65

Gene sequence:

>999_bases
ATGTCAGTAACGATTAAAGATATCGCCAGGCTGGCGAATGTATCGCACACCACAGTATCCAGAGCGCTGAACAACAGTCC
GCTGATAAAAGAGAACACGAAAAAGAAAATACTCGACATCGCAGCCGAAATGAATTATAAACCGAATTTTAATGCGAAAA
GCCTTGTCACGCAAAAGTCTTTTACGATCGGCCTGTTTTTAACAAGCCTGACAGACGGGACGTCTTCAAGTTTCTTTGCA
GACATCCTGCGCGGCGTCAACAAGGTGATCGATGAAAACTATAATATGGTTGTCAGGGGAATCGACGATTATCATGATTT
GTCATCCATTCACCGCAACCGCTATGACGGCATGATTTTAATCAGCCAAAGCGAACAGGATCAGGCTTTTATTGAGCATG
TCCTCAAACAGAATATTCCGGTCGTCGTGCTGAACAGAAAAATCGAAGGGCACTCCGTTGTCAATATACTGGCGAATGAA
CACGAGGGCGCTTTCCTCGCTGCTTCATACTTGATCAAAAACGGCCACAAACAGATCGCCATGGTGCAGGGGAAAGAAGG
CTTTAAATCGTCTCAAGAAAGGAAAGGAGGCTTTCTTCGCGCGCTTCGCGACTCAAACCTTGATATGCCCGGCGAATACC
TCGTTCAAGGCGATTATACGATGCAAAGCGGCTTTCGCGCGGCTGAAACGCTGCTAAAGCTGAAGAATCCTCCGACAGCC
CTGTTTTGCGCCAATGATGATATGGCGATCGGCGCGATGAACGCCCTCTATGCAAACGGGAAACGCTGTCCTGACAATAT
GTCGATTATCGGCTTTGACGATAGCGGATTTTCGGCGTATACGACACCGTCATTGACGACGGTAAAAAAACCGACTGAAA
AAATCAGCATGCTTGGTGCGGAAAGCCTGCTGTCATTGATCGAAAACCCGCAGGCAGAAGGCGGGCAGACGCTCATCAGC
ACGGAGCTGATCATTCGCAATTCAGTTAAGCATCTATAG

Upstream 100 bases:

>100_bases
GAAATCAAAGCGAGAACATAGCGGAAATTCACTTTCTAAAAAGCGCTTTTGATATGGTAAACTGATGGTAACAACAGCAA
GAAAAGGCGGGTAAAAAACA

Downstream 100 bases:

>100_bases
CATCATTTTTTTGATGCGCTGTAAAATGTGAACGTGTGCAGAAATGAGGAGGGGATTGAAATGGAGAGGCTGTCCAAACG
GATAAGGTCTAAGCCGAGCC

Product: ExuR

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSVTIKDIARLANVSHTTVSRALNNSPLIKENTKKKILDIAAEMNYKPNFNAKSLVTQKSFTIGLFLTSLTDGTSSSFFA
DILRGVNKVIDENYNMVVRGIDDYHDLSSIHRNRYDGMILISQSEQDQAFIEHVLKQNIPVVVLNRKIEGHSVVNILANE
HEGAFLAASYLIKNGHKQIAMVQGKEGFKSSQERKGGFLRALRDSNLDMPGEYLVQGDYTMQSGFRAAETLLKLKNPPTA
LFCANDDMAIGAMNALYANGKRCPDNMSIIGFDDSGFSAYTTPSLTTVKKPTEKISMLGAESLLSLIENPQAEGGQTLIS
TELIIRNSVKHL

Sequences:

>Translated_332_residues
MSVTIKDIARLANVSHTTVSRALNNSPLIKENTKKKILDIAAEMNYKPNFNAKSLVTQKSFTIGLFLTSLTDGTSSSFFA
DILRGVNKVIDENYNMVVRGIDDYHDLSSIHRNRYDGMILISQSEQDQAFIEHVLKQNIPVVVLNRKIEGHSVVNILANE
HEGAFLAASYLIKNGHKQIAMVQGKEGFKSSQERKGGFLRALRDSNLDMPGEYLVQGDYTMQSGFRAAETLLKLKNPPTA
LFCANDDMAIGAMNALYANGKRCPDNMSIIGFDDSGFSAYTTPSLTTVKKPTEKISMLGAESLLSLIENPQAEGGQTLIS
TELIIRNSVKHL
>Mature_331_residues
SVTIKDIARLANVSHTTVSRALNNSPLIKENTKKKILDIAAEMNYKPNFNAKSLVTQKSFTIGLFLTSLTDGTSSSFFAD
ILRGVNKVIDENYNMVVRGIDDYHDLSSIHRNRYDGMILISQSEQDQAFIEHVLKQNIPVVVLNRKIEGHSVVNILANEH
EGAFLAASYLIKNGHKQIAMVQGKEGFKSSQERKGGFLRALRDSNLDMPGEYLVQGDYTMQSGFRAAETLLKLKNPPTAL
FCANDDMAIGAMNALYANGKRCPDNMSIIGFDDSGFSAYTTPSLTTVKKPTEKISMLGAESLLSLIENPQAEGGQTLIST
ELIIRNSVKHL

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=31.1377245508982, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1788474, Length=307, Percent_Identity=33.8762214983713, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=31.5789473684211, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1790194, Length=333, Percent_Identity=30.03003003003, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=32.5423728813559, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789068, Length=308, Percent_Identity=30.8441558441558, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1786540, Length=333, Percent_Identity=30.03003003003, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=28.4810126582279, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI48994940, Length=312, Percent_Identity=26.9230769230769, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790715, Length=314, Percent_Identity=26.7515923566879, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787906, Length=337, Percent_Identity=22.8486646884273, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1789456, Length=305, Percent_Identity=24.9180327868852, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1786268, Length=331, Percent_Identity=21.4501510574018, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790192, Length=214, Percent_Identity=28.5046728971963, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790689, Length=298, Percent_Identity=23.1543624161074, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36578; Mature: 36447

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTIKDIARLANVSHTTVSRALNNSPLIKENTKKKILDIAAEMNYKPNFNAKSLVTQKS
CCEEHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHEECC
FTIGLFLTSLTDGTSSSFFADILRGVNKVIDENYNMVVRGIDDYHDLSSIHRNRYDGMIL
EEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCEEE
ISQSEQDQAFIEHVLKQNIPVVVLNRKIEGHSVVNILANEHEGAFLAASYLIKNGHKQIA
EECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEE
MVQGKEGFKSSQERKGGFLRALRDSNLDMPGEYLVQGDYTMQSGFRAAETLLKLKNPPTA
EEECCCCCCCCHHHCCHHHHHHHCCCCCCCCCEEEECCCHHHHCHHHHHHHHHCCCCCCE
LFCANDDMAIGAMNALYANGKRCPDNMSIIGFDDSGFSAYTTPSLTTVKKPTEKISMLGA
EEECCCCCEEHHHHHHHCCCCCCCCCCEEEEECCCCCCEECCCCCEECCCCHHHHHHHHH
ESLLSLIENPQAEGGQTLISTELIIRNSVKHL
HHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
SVTIKDIARLANVSHTTVSRALNNSPLIKENTKKKILDIAAEMNYKPNFNAKSLVTQKS
CEEHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHEECC
FTIGLFLTSLTDGTSSSFFADILRGVNKVIDENYNMVVRGIDDYHDLSSIHRNRYDGMIL
EEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCEEE
ISQSEQDQAFIEHVLKQNIPVVVLNRKIEGHSVVNILANEHEGAFLAASYLIKNGHKQIA
EECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEE
MVQGKEGFKSSQERKGGFLRALRDSNLDMPGEYLVQGDYTMQSGFRAAETLLKLKNPPTA
EEECCCCCCCCHHHCCHHHHHHHCCCCCCCCCEEEECCCHHHHCHHHHHHHHHCCCCCCE
LFCANDDMAIGAMNALYANGKRCPDNMSIIGFDDSGFSAYTTPSLTTVKKPTEKISMLGA
EEECCCCCEEHHHHHHHCCCCCCCCCCEEEEECCCCCCEECCCCCEECCCCHHHHHHHHH
ESLLSLIENPQAEGGQTLISTELIIRNSVKHL
HHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]