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The map label for this gene is uppP

Identifier: 52786988

GI number: 52786988

Start: 3153015

End: 3153845

Strand: Reverse

Name: uppP

Synonym: BLi03290

Alternate gene names: 52786988

Gene position: 3153845-3153015 (Counterclockwise)

Preceding gene: 52786989

Following gene: 52786987

Centisome position: 74.69

GC content: 48.38

Gene sequence:

>831_bases
ATGAACATTTGGGATATTATTGTCGCTATCATACTTGGAATTGTTGAAGGATTAACCGAATATGCCCCTGTATCGTCAAC
AGGGCATATGATTATTGTTGACGATGTCTGGCTGAAATCGAAAGAACTGCTTACGCCGGAGGCGGCGAATACCTTTAAAG
TCGTGATTCAGCTCGGCTCCATCCTTGCCGTCGCCTTCGTATTTAAAGACCGGATTCTCAATCTTTTAGGCATGAAGAAA
AACATTACGGAAGAGCAGAAATCGGGAAACCGCCTTTCCATCGCCCAAATCGCTGTAGGCCTTGTTCCCGCCGCTGTGCT
TGGATTTTTATTTGAAGACTATATTGATCAATACTTGTTTTCCGTCCGCACCGTTGCGGTCGGTCTCATCGCCGGTGCGG
TGCTGATGCTCGCAGCCGACTGGATCAATCGGCGCAAGGATACGACAGATTCGGTTGATAGGATGACGTATAAGCAGGCG
CTTGGCATGGGGCTGTTTCAATGTCTGGCGCTTTGGCCGGGCTTCTCGCGCTCGGGTTCGACGATTTCAGGCGGGGTTAT
TCTCGGCTTGAGCCACAGAGCGGCCGCTGATTTCACCTTCATCATGGCGATTCCGATCATGATGGGTGCAAGCCTGCTCT
CTTTAATCAAAAACTGGGCATATTTGAGTGCAGACCTGTTGCCTTTCTTTATCGCAGGGTTTATCAGCGCTTTTATTGTC
GCTCTTTTTGTCGTCCGTTTTTTCCTCCGGCTGATCAACAAGATCAAGCTGGTTCCGTTTGCCATCTATCGAATCGTTTT
AGGGCTGCTTCTGTTCATTTTGTTTCTGTAA

Upstream 100 bases:

>100_bases
ACGAAAAAAACGAAGAAGTCTGAATCCCGCTTGCATAATCGGCTTTTAATATAAATAGTTTATTAGAGGACAAGTTTTAA
GGAAGCGAAAGGAATGACAT

Downstream 100 bases:

>100_bases
GAGTGAAAATGCGAACCGATTTCCGGCTGGAAATCGGTTTTGTTATGGGTAAAAAGAATGATATTCTATTATTTCCCACT
GTAAAACCGCCTGCCAACTT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNIWDIIVAIILGIVEGLTEYAPVSSTGHMIIVDDVWLKSKELLTPEAANTFKVVIQLGSILAVAFVFKDRILNLLGMKK
NITEEQKSGNRLSIAQIAVGLVPAAVLGFLFEDYIDQYLFSVRTVAVGLIAGAVLMLAADWINRRKDTTDSVDRMTYKQA
LGMGLFQCLALWPGFSRSGSTISGGVILGLSHRAAADFTFIMAIPIMMGASLLSLIKNWAYLSADLLPFFIAGFISAFIV
ALFVVRFFLRLINKIKLVPFAIYRIVLGLLLFILFL

Sequences:

>Translated_276_residues
MNIWDIIVAIILGIVEGLTEYAPVSSTGHMIIVDDVWLKSKELLTPEAANTFKVVIQLGSILAVAFVFKDRILNLLGMKK
NITEEQKSGNRLSIAQIAVGLVPAAVLGFLFEDYIDQYLFSVRTVAVGLIAGAVLMLAADWINRRKDTTDSVDRMTYKQA
LGMGLFQCLALWPGFSRSGSTISGGVILGLSHRAAADFTFIMAIPIMMGASLLSLIKNWAYLSADLLPFFIAGFISAFIV
ALFVVRFFLRLINKIKLVPFAIYRIVLGLLLFILFL
>Mature_276_residues
MNIWDIIVAIILGIVEGLTEYAPVSSTGHMIIVDDVWLKSKELLTPEAANTFKVVIQLGSILAVAFVFKDRILNLLGMKK
NITEEQKSGNRLSIAQIAVGLVPAAVLGFLFEDYIDQYLFSVRTVAVGLIAGAVLMLAADWINRRKDTTDSVDRMTYKQA
LGMGLFQCLALWPGFSRSGSTISGGVILGLSHRAAADFTFIMAIPIMMGASLLSLIKNWAYLSADLLPFFIAGFISAFIV
ALFVVRFFLRLINKIKLVPFAIYRIVLGLLLFILFL

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=276, Percent_Identity=46.0144927536232, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_BACLD (Q65FP0)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080399.1
- RefSeq:   YP_092817.1
- STRING:   Q65FP0
- EnsemblBacteria:   EBBACT00000054346
- EnsemblBacteria:   EBBACT00000059139
- GeneID:   3027920
- GeneID:   3099356
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03290
- KEGG:   bli:BL02576
- NMPDR:   fig|279010.5.peg.2854
- eggNOG:   COG1968
- GeneTree:   EBGT00050000002490
- HOGENOM:   HBG391969
- OMA:   IGHFIGF
- ProtClustDB:   PRK00281
- BioCyc:   BLIC279010-1:BLI03290-MONOMER
- BioCyc:   BLIC279010:BL02576-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30371; Mature: 30371

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11dc0414)-; HASH(0x122ab0bc)-; HASH(0x122b669c)-; HASH(0x122ab20c)-; HASH(0x122b66f0)-; HASH(0x1226f55c)-; HASH(0x122a6168)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIWDIIVAIILGIVEGLTEYAPVSSTGHMIIVDDVWLKSKELLTPEAANTFKVVIQLGS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHCHHHHCCCCCHHHHHHHHHHHH
ILAVAFVFKDRILNLLGMKKNITEEQKSGNRLSIAQIAVGLVPAAVLGFLFEDYIDQYLF
HHHHHHHHHHHHHHHHCCHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVRTVAVGLIAGAVLMLAADWINRRKDTTDSVDRMTYKQALGMGLFQCLALWPGFSRSGS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TISGGVILGLSHRAAADFTFIMAIPIMMGASLLSLIKNWAYLSADLLPFFIAGFISAFIV
EECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFVVRFFLRLINKIKLVPFAIYRIVLGLLLFILFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MNIWDIIVAIILGIVEGLTEYAPVSSTGHMIIVDDVWLKSKELLTPEAANTFKVVIQLGS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHCHHHHCCCCCHHHHHHHHHHHH
ILAVAFVFKDRILNLLGMKKNITEEQKSGNRLSIAQIAVGLVPAAVLGFLFEDYIDQYLF
HHHHHHHHHHHHHHHHCCHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVRTVAVGLIAGAVLMLAADWINRRKDTTDSVDRMTYKQALGMGLFQCLALWPGFSRSGS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TISGGVILGLSHRAAADFTFIMAIPIMMGASLLSLIKNWAYLSADLLPFFIAGFISAFIV
EECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFVVRFFLRLINKIKLVPFAIYRIVLGLLLFILFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA