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The map label for this gene is bmrR [H]

Identifier: 52786519

GI number: 52786519

Start: 2673221

End: 2674066

Strand: Reverse

Name: bmrR [H]

Synonym: BLi02784

Alternate gene names: 52786519

Gene position: 2674066-2673221 (Counterclockwise)

Preceding gene: 52786520

Following gene: 52786518

Centisome position: 63.33

GC content: 36.17

Gene sequence:

>846_bases
ATGAAGGAATATTTTTCAATCGGGGAAACAGCCCGTCTAAATAACATTTCCATTCAAACATTGCGCTATTATGATAAGAT
CGGAATTTTCAAGCCTCAATGTACAGACCGGGATAACGGCTATCGATATTACCATGTTAAACAGTTCTTTTATTTGGATA
TTATAAAATATCTCAAATCCATTAAAACGCCTTTGGAAGAAATTAAGCGCATTATCTCACATACATCTGCCCCTGAACTG
ATGCAAACCTTTCTTGAGGAGCAAGAAAACGTTATTGAGCGTGAAATGGAAAAACTCGAACGTGCCAGGCAATTGCTTCA
AAGAAGAAAGGACCAGCTTCATGAACAATTGGAGATACGCGCTAAAAAAGAAGAAGGTCTGGTGTATGTTCGGCATATAG
AAGGCCAAACCATTTTAAAAGCAGCGACACCTCAAGTGAATCCTCATGACCAATCAGATTTGTATTACCGAAAACTGGCT
GAGGTCCTGGAAGAAAGAGGAGATATGGTCGATAACTATTATGGACTGATTTATGATTTAAAGCCTTATAAAAATTCAGG
TGACATTTATTGCAACAGTGTTTATACGACGATTTACGATGGAGCAAAGATAGATACAGAAGAACAAAATATTGGGATGG
ATACGATCCCATCCGGTGAATATGTGTGTATTTCATTTGATTGCTCTTCAACAAATTATTTTTCATACTATCAAAAACTG
TACCATTTTATTGAAACTCATGGCATTCAAACGGATGGAAAAGTATATCAAGTTTCTTTTCCAAACAGCTATAACTCATT
AAAAGAAGAAGACTTCCTCACAGAATTCAGAGTGCTGAAAAAATAA

Upstream 100 bases:

>100_bases
TTTTCCGTCCGTCCAAGATGTTGATGTAATTTTTCACTTTTTGAAGGTAATTGTGGAGAGGAAGGATAATTCTTAGAACT
AAGAAGAAAGGATGGGATTC

Downstream 100 bases:

>100_bases
CGAACTCCTTGACCCTATAGTTGCTATAGGGTTTATCATTTATGCATCGTTCTTATGAATATTTGAAAGGAAGGGTATAT
AAGTGGCAGAAAATAAGACG

Product: BmrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKEYFSIGETARLNNISIQTLRYYDKIGIFKPQCTDRDNGYRYYHVKQFFYLDIIKYLKSIKTPLEEIKRIISHTSAPEL
MQTFLEEQENVIEREMEKLERARQLLQRRKDQLHEQLEIRAKKEEGLVYVRHIEGQTILKAATPQVNPHDQSDLYYRKLA
EVLEERGDMVDNYYGLIYDLKPYKNSGDIYCNSVYTTIYDGAKIDTEEQNIGMDTIPSGEYVCISFDCSSTNYFSYYQKL
YHFIETHGIQTDGKVYQVSFPNSYNSLKEEDFLTEFRVLKK

Sequences:

>Translated_281_residues
MKEYFSIGETARLNNISIQTLRYYDKIGIFKPQCTDRDNGYRYYHVKQFFYLDIIKYLKSIKTPLEEIKRIISHTSAPEL
MQTFLEEQENVIEREMEKLERARQLLQRRKDQLHEQLEIRAKKEEGLVYVRHIEGQTILKAATPQVNPHDQSDLYYRKLA
EVLEERGDMVDNYYGLIYDLKPYKNSGDIYCNSVYTTIYDGAKIDTEEQNIGMDTIPSGEYVCISFDCSSTNYFSYYQKL
YHFIETHGIQTDGKVYQVSFPNSYNSLKEEDFLTEFRVLKK
>Mature_281_residues
MKEYFSIGETARLNNISIQTLRYYDKIGIFKPQCTDRDNGYRYYHVKQFFYLDIIKYLKSIKTPLEEIKRIISHTSAPEL
MQTFLEEQENVIEREMEKLERARQLLQRRKDQLHEQLEIRAKKEEGLVYVRHIEGQTILKAATPQVNPHDQSDLYYRKLA
EVLEERGDMVDNYYGLIYDLKPYKNSGDIYCNSVYTTIYDGAKIDTEEQNIGMDTIPSGEYVCISFDCSSTNYFSYYQKL
YHFIETHGIQTDGKVYQVSFPNSYNSLKEEDFLTEFRVLKK

Specific function: Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind; PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 33376; Mature: 33376

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYFSIGETARLNNISIQTLRYYDKIGIFKPQCTDRDNGYRYYHVKQFFYLDIIKYLKS
CCCCCCCCCCCEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
IKTPLEEIKRIISHTSAPELMQTFLEEQENVIEREMEKLERARQLLQRRKDQLHEQLEIR
HCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKKEEGLVYVRHIEGQTILKAATPQVNPHDQSDLYYRKLAEVLEERGDMVDNYYGLIYDL
EECCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCEEEEEE
KPYKNSGDIYCNSVYTTIYDGAKIDTEEQNIGMDTIPSGEYVCISFDCSSTNYFSYYQKL
CCCCCCCCEEEEEEEEEEECCCCCCCCHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
YHFIETHGIQTDGKVYQVSFPNSYNSLKEEDFLTEFRVLKK
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEYFSIGETARLNNISIQTLRYYDKIGIFKPQCTDRDNGYRYYHVKQFFYLDIIKYLKS
CCCCCCCCCCCEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
IKTPLEEIKRIISHTSAPELMQTFLEEQENVIEREMEKLERARQLLQRRKDQLHEQLEIR
HCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKKEEGLVYVRHIEGQTILKAATPQVNPHDQSDLYYRKLAEVLEERGDMVDNYYGLIYDL
EECCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCEEEEEE
KPYKNSGDIYCNSVYTTIYDGAKIDTEEQNIGMDTIPSGEYVCISFDCSSTNYFSYYQKL
CCCCCCCCEEEEEEEEEEECCCCCCCCHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
YHFIETHGIQTDGKVYQVSFPNSYNSLKEEDFLTEFRVLKK
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961792; 8969508; 9384377; 10568751; 10025401; 11201751 [H]