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The map label for this gene is yluC

Identifier: 52785636

GI number: 52785636

Start: 1829316

End: 1830575

Strand: Direct

Name: yluC

Synonym: BLi01877

Alternate gene names: 52785636

Gene position: 1829316-1830575 (Clockwise)

Preceding gene: 52785635

Following gene: 52785637

Centisome position: 43.32

GC content: 49.92

Gene sequence:

>1260_bases
GTGAATACTGTGATCGCGTTTATTCTTATTTTTGGAACGCTCGTATTTTTCCATGAGCTTGGTCATCTCATCCTTGCTCA
AAGAGCCGGAATACTGTGCCGGGAGTTTGCTATCGGCTTCGGTCCGAAAATCTTTTCGTTTAAGAAAAATGAGACCGTTT
ATACGATCAGGCTTCTTCCGATCGGCGGCTTTGTCAGAATGGCCGGCGAAGATCCTGAGATGATTGAAGTGAAGCCCGGT
TATACGGTCGGGCTGTTGTTCGACAGCGAAAACAAGGTCGAAAAGATCATTATCAACCAAAAAGAAAAGTATCCCGACGC
ATTGGTCATTGAAGTGGAGCAGGCCGACCTGGAGCACCAGATGAGGATTACGGGCTATGAGCACGGCAATGAAGATCATC
TCTCTTCATTTTCTGTCAGTGAAACGTCCTTTTTCATCGTAGACGGGGAAGAAGTCCAGATCGCTCCTTACAACCGCCAA
TTTCATTCGAAAACGGTTTGGCAGCGCATCAAAGCGATTGCTGCCGGACCGATCATGAACTTTATTTTGGCTTATGTCAT
ACTCGTGATGCTCGGACTGATGCAGGGAGTGCCGTCTGACGAGCCGGTGCTCGGCAAGTTGATAGACAACGGACGGGCGG
CGGAAGCAGGCCTCCAGGAGGGAGACCGCATTCAAACGATCAACGGGGAGAACATGAGGTCGTGGACGGATATTGTCAAC
ACGGTCAGAGAACACCCTGAAAAAGAACTGAAAATCGTTTTGATGCGCGACAATGTCAAGCTGACGAAATACGTAACACC
TGAAGCTGTCAAGGCAGGGGATGAAACCGTCGGCAGATTCGGCGCTTACAATCCTGTGAAAACAGGCGTTCTGACATCGA
TTTCCTACGGTGCGACCGAAACGGCGACAGTGGCCCAGAGCATCGTCACCAATCTCGGAAAGCTCGTCACAGGACAATTC
TCAATCGACATGCTGGCCGGTCCTGTCGGCATTTATGACATGACAGACCAAGTGGCCAAGACAGGCGTTATCAACCTGCT
GAAGCTGGCCGCATTTTTAAGCATCAACCTCGGGATCGTCAACCTTCTGCCAATCCCTGCGCTGGACGGCGGAAGACTGT
TGTTCCTGTTTATTGAAGCGATCCGCGGGAAGCCGATCAACCGCGAAAAAGAAGCGTTTGTCGTCTTTATCGGCGTCGCA
TTTTTGATGCTCCTAATGCTTGTCGTCACATGGAACGATATCCAGCGCTTATTTCTGTAA

Upstream 100 bases:

>100_bases
CCATCAGGTGATCGCAAAGCCGAGCCTTCAAGAGATCCGTGAAGTGGACAAAGACGCCAGAAAGTTTGTCCAAACATTAC
TCACATAAGGTGGTATGTTC

Downstream 100 bases:

>100_bases
AACCAATCGCCTTTTTTAAGTGCAGCCAAGCCTTTTAAAAGGCTCTTTTTTAGGGACACCGTTCCCGACTCAAAAAAGTA
ACCAACTGAAACAAATGAGG

Product: YluC

Products: NA

Alternate protein names: Regulating alternative sigma factor protease; Regulating anti-sigma-W factor activity protease

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNTVIAFILIFGTLVFFHELGHLILAQRAGILCREFAIGFGPKIFSFKKNETVYTIRLLPIGGFVRMAGEDPEMIEVKPG
YTVGLLFDSENKVEKIIINQKEKYPDALVIEVEQADLEHQMRITGYEHGNEDHLSSFSVSETSFFIVDGEEVQIAPYNRQ
FHSKTVWQRIKAIAAGPIMNFILAYVILVMLGLMQGVPSDEPVLGKLIDNGRAAEAGLQEGDRIQTINGENMRSWTDIVN
TVREHPEKELKIVLMRDNVKLTKYVTPEAVKAGDETVGRFGAYNPVKTGVLTSISYGATETATVAQSIVTNLGKLVTGQF
SIDMLAGPVGIYDMTDQVAKTGVINLLKLAAFLSINLGIVNLLPIPALDGGRLLFLFIEAIRGKPINREKEAFVVFIGVA
FLMLLMLVVTWNDIQRLFL

Sequences:

>Translated_419_residues
MNTVIAFILIFGTLVFFHELGHLILAQRAGILCREFAIGFGPKIFSFKKNETVYTIRLLPIGGFVRMAGEDPEMIEVKPG
YTVGLLFDSENKVEKIIINQKEKYPDALVIEVEQADLEHQMRITGYEHGNEDHLSSFSVSETSFFIVDGEEVQIAPYNRQ
FHSKTVWQRIKAIAAGPIMNFILAYVILVMLGLMQGVPSDEPVLGKLIDNGRAAEAGLQEGDRIQTINGENMRSWTDIVN
TVREHPEKELKIVLMRDNVKLTKYVTPEAVKAGDETVGRFGAYNPVKTGVLTSISYGATETATVAQSIVTNLGKLVTGQF
SIDMLAGPVGIYDMTDQVAKTGVINLLKLAAFLSINLGIVNLLPIPALDGGRLLFLFIEAIRGKPINREKEAFVVFIGVA
FLMLLMLVVTWNDIQRLFL
>Mature_419_residues
MNTVIAFILIFGTLVFFHELGHLILAQRAGILCREFAIGFGPKIFSFKKNETVYTIRLLPIGGFVRMAGEDPEMIEVKPG
YTVGLLFDSENKVEKIIINQKEKYPDALVIEVEQADLEHQMRITGYEHGNEDHLSSFSVSETSFFIVDGEEVQIAPYNRQ
FHSKTVWQRIKAIAAGPIMNFILAYVILVMLGLMQGVPSDEPVLGKLIDNGRAAEAGLQEGDRIQTINGENMRSWTDIVN
TVREHPEKELKIVLMRDNVKLTKYVTPEAVKAGDETVGRFGAYNPVKTGVLTSISYGATETATVAQSIVTNLGKLVTGQF
SIDMLAGPVGIYDMTDQVAKTGVINLLKLAAFLSINLGIVNLLPIPALDGGRLLFLFIEAIRGKPINREKEAFVVFIGVA
FLMLLMLVVTWNDIQRLFL

Specific function: Is responsible for Site-2 cleavage of the RsiW anti- sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=238, Percent_Identity=35.7142857142857, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RASP_BACLD (Q65JJ2)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079050.1
- RefSeq:   YP_091465.1
- ProteinModelPortal:   Q65JJ2
- STRING:   Q65JJ2
- MEROPS:   M50.004
- EnsemblBacteria:   EBBACT00000057328
- EnsemblBacteria:   EBBACT00000059386
- GeneID:   3031071
- GeneID:   3100160
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01877
- KEGG:   bli:BL01236
- NMPDR:   fig|279010.5.peg.2581
- eggNOG:   COG0750
- GeneTree:   EBGT00050000001607
- HOGENOM:   HBG664087
- OMA:   HGTEFVV
- ProtClustDB:   CLSK2460922
- BioCyc:   BLIC279010-1:BLI01877-MONOMER
- BioCyc:   BLIC279010:BL01236-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 46451; Mature: 46451

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 19-19

Signals:

None

Transmembrane regions:

HASH(0xe26084c)-; HASH(0xe96fbf0)-; HASH(0xe5afb98)-; HASH(0xf582a1c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVIAFILIFGTLVFFHELGHLILAQRAGILCREFAIGFGPKIFSFKKNETVYTIRLLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCEEEEEEEEE
IGGFVRMAGEDPEMIEVKPGYTVGLLFDSENKVEKIIINQKEKYPDALVIEVEQADLEHQ
CCCEEEECCCCCCEEEECCCEEEEEEECCCCCEEHEEECCCCCCCCEEEEEEECCCCCCE
MRITGYEHGNEDHLSSFSVSETSFFIVDGEEVQIAPYNRQFHSKTVWQRIKAIAAGPIMN
EEEECCCCCCCHHCCCCEECCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
FILAYVILVMLGLMQGVPSDEPVLGKLIDNGRAAEAGLQEGDRIQTINGENMRSWTDIVN
HHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHCCCCCCCEEEEECCCCCHHHHHHHH
TVREHPEKELKIVLMRDNVKLTKYVTPEAVKAGDETVGRFGAYNPVKTGVLTSISYGATE
HHHHCCCCCEEEEEEECCEEEEEEECHHHHHCCCHHHHHCCCCCCHHHHHHHEECCCCCH
TATVAQSIVTNLGKLVTGQFSIDMLAGPVGIYDMTDQVAKTGVINLLKLAAFLSINLGIV
HHHHHHHHHHHHHHHHCCCEEEEEHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEE
NLLPIPALDGGRLLFLFIEAIRGKPINREKEAFVVFIGVAFLMLLMLVVTWNDIQRLFL
EEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNTVIAFILIFGTLVFFHELGHLILAQRAGILCREFAIGFGPKIFSFKKNETVYTIRLLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCEEEEEEEEE
IGGFVRMAGEDPEMIEVKPGYTVGLLFDSENKVEKIIINQKEKYPDALVIEVEQADLEHQ
CCCEEEECCCCCCEEEECCCEEEEEEECCCCCEEHEEECCCCCCCCEEEEEEECCCCCCE
MRITGYEHGNEDHLSSFSVSETSFFIVDGEEVQIAPYNRQFHSKTVWQRIKAIAAGPIMN
EEEECCCCCCCHHCCCCEECCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
FILAYVILVMLGLMQGVPSDEPVLGKLIDNGRAAEAGLQEGDRIQTINGENMRSWTDIVN
HHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHCCCCCCCEEEEECCCCCHHHHHHHH
TVREHPEKELKIVLMRDNVKLTKYVTPEAVKAGDETVGRFGAYNPVKTGVLTSISYGATE
HHHHCCCCCEEEEEEECCEEEEEEECHHHHHCCCHHHHHCCCCCCHHHHHHHEECCCCCH
TATVAQSIVTNLGKLVTGQFSIDMLAGPVGIYDMTDQVAKTGVINLLKLAAFLSINLGIV
HHHHHHHHHHHHHHHHCCCEEEEEHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEE
NLLPIPALDGGRLLFLFIEAIRGKPINREKEAFVVFIGVAFLMLLMLVVTWNDIQRLFL
EEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA