| Definition | Bacillus licheniformis ATCC 14580, complete genome. |
|---|---|
| Accession | NC_006322 |
| Length | 4,222,645 |
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The map label for this gene is dxr
Identifier: 52785635
GI number: 52785635
Start: 1828152
End: 1829303
Strand: Direct
Name: dxr
Synonym: BLi01876
Alternate gene names: 52785635
Gene position: 1828152-1829303 (Clockwise)
Preceding gene: 52785634
Following gene: 52785636
Centisome position: 43.29
GC content: 48.18
Gene sequence:
>1152_bases TTGAAGAACATATGTCTATTGGGAGCGACAGGCTCCATAGGAGAACAGACGCTTGATGTCATCAAAGCGCATGACGATAA GTTTCGGCTGACCGCCATGACTTTCGGCAAAAACGCCGAAAAAGCGGCAGAAATCATTGAAACCTTTAAACCGAAGTATG TAGGCGTCGGGGATGAGCATACATATGAAACATTAAAACAGCATTCTTTCTCCTACACCTTTAAAACAGGGATCGGGGAG GAAGCTTTAATCGAAGCGGCCGTTATCCCGGAAGCGGATATCGTCGTCAATGCTCTCGTCGGCAGCGTCGGTCTTCTTCC GACTTTAAAGGCGATGGAGCATAAAAAAACAATTGCGCTTGCAAATAAGGAAACTCTCGTGACAGCCGGTCATATAGTGA AAGAACACGCCCAAAAATACGATGTCCCGCTCCTGCCCGTCGACAGCGAACATTCCGCGATTTTCCAGGCCCTTCAGGGG GAAAATCCGAAGCATATCAAACGGCTGATCGTCACGGCTTCAGGCGGCAGCTTCAGGGACAGAACAAGGCGGGAACTTGA AGGCGTCACAGTGGAAGAAGCCCTCAATCATCCAAATTGGTCGATGGGTGCAAAAATCACGATCGATTCGGCTACAATGA TGAATAAAGGACTCGAGGTTATTGAAGCCCACTGGCTGTTTGATCTGCCCTATGACCAGATCGATGTCCTCCTTCACAAA GAAAGCATTATTCATTCAATGGTTGAATTCCACGACCGCAGCGTCATCGCCCAGCTTGGCACACCTGATATGAGAGTGCC GATTCAATATGCGCTCAGCCATCCGGAACGCCTGCCGTTTAATGAAGCAAAATCCCTCGATCTCTGGGAAGTCGGACAGC TGAATTTTGCCCAAGCTGATTTTGAAAGGTTCCGCTGCTTACAATTCGCTTATGAATCAGGTAAAATAGGCGGTACAATG CCGACTGTTTTAAACGCGGCCAACGAGGAAGCCGTTGCGGCATTTCTTTCGGGCAGGATTTCCTTTCTTGGAATAGAAGA CATCATTGAAAAGGCTTTGGAACGCCATCAGGTGATCGCAAAGCCGAGCCTTCAAGAGATCCGTGAAGTGGACAAAGACG CCAGAAAGTTTGTCCAAACATTACTCACATAA
Upstream 100 bases:
>100_bases GTCATGCCGGTTCTGTACTTCCTGCTTGTTCTTTTTCAGCCGTTCGGGCTATGATAGAAAAGGGTACTGATAGCTAGAAA GAAACAGAGGTGCGGCAATT
Downstream 100 bases:
>100_bases GGTGGTATGTTCGTGAATACTGTGATCGCGTTTATTCTTATTTTTGGAACGCTCGTATTTTTCCATGAGCTTGGTCATCT CATCCTTGCTCAAAGAGCCG
Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Products: NA
Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase
Number of amino acids: Translated: 383; Mature: 383
Protein sequence:
>383_residues MKNICLLGATGSIGEQTLDVIKAHDDKFRLTAMTFGKNAEKAAEIIETFKPKYVGVGDEHTYETLKQHSFSYTFKTGIGE EALIEAAVIPEADIVVNALVGSVGLLPTLKAMEHKKTIALANKETLVTAGHIVKEHAQKYDVPLLPVDSEHSAIFQALQG ENPKHIKRLIVTASGGSFRDRTRRELEGVTVEEALNHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDLPYDQIDVLLHK ESIIHSMVEFHDRSVIAQLGTPDMRVPIQYALSHPERLPFNEAKSLDLWEVGQLNFAQADFERFRCLQFAYESGKIGGTM PTVLNAANEEAVAAFLSGRISFLGIEDIIEKALERHQVIAKPSLQEIREVDKDARKFVQTLLT
Sequences:
>Translated_383_residues MKNICLLGATGSIGEQTLDVIKAHDDKFRLTAMTFGKNAEKAAEIIETFKPKYVGVGDEHTYETLKQHSFSYTFKTGIGE EALIEAAVIPEADIVVNALVGSVGLLPTLKAMEHKKTIALANKETLVTAGHIVKEHAQKYDVPLLPVDSEHSAIFQALQG ENPKHIKRLIVTASGGSFRDRTRRELEGVTVEEALNHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDLPYDQIDVLLHK ESIIHSMVEFHDRSVIAQLGTPDMRVPIQYALSHPERLPFNEAKSLDLWEVGQLNFAQADFERFRCLQFAYESGKIGGTM PTVLNAANEEAVAAFLSGRISFLGIEDIIEKALERHQVIAKPSLQEIREVDKDARKFVQTLLT >Mature_383_residues MKNICLLGATGSIGEQTLDVIKAHDDKFRLTAMTFGKNAEKAAEIIETFKPKYVGVGDEHTYETLKQHSFSYTFKTGIGE EALIEAAVIPEADIVVNALVGSVGLLPTLKAMEHKKTIALANKETLVTAGHIVKEHAQKYDVPLLPVDSEHSAIFQALQG ENPKHIKRLIVTASGGSFRDRTRRELEGVTVEEALNHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDLPYDQIDVLLHK ESIIHSMVEFHDRSVIAQLGTPDMRVPIQYALSHPERLPFNEAKSLDLWEVGQLNFAQADFERFRCLQFAYESGKIGGTM PTVLNAANEEAVAAFLSGRISFLGIEDIIEKALERHQVIAKPSLQEIREVDKDARKFVQTLLT
Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COG id: COG0743
COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DXR family
Homologues:
Organism=Escherichia coli, GI1786369, Length=395, Percent_Identity=41.7721518987342, Blast_Score=294, Evalue=6e-81,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DXR_BACLD (Q65JJ3)
Other databases:
- EMBL: AE017333 - EMBL: CP000002 - RefSeq: YP_079049.1 - RefSeq: YP_091464.1 - ProteinModelPortal: Q65JJ3 - SMR: Q65JJ3 - STRING: Q65JJ3 - EnsemblBacteria: EBBACT00000056508 - EnsemblBacteria: EBBACT00000060387 - GeneID: 3031070 - GeneID: 3101494 - GenomeReviews: AE017333_GR - GenomeReviews: CP000002_GR - KEGG: bld:BLi01876 - KEGG: bli:BL01237 - NMPDR: fig|279010.5.peg.2580 - eggNOG: COG0743 - GeneTree: EBGT00050000001768 - HOGENOM: HBG430762 - OMA: IHSMVEY - ProtClustDB: PRK05447 - BioCyc: BLIC279010-1:BLI01876-MONOMER - BioCyc: BLIC279010:BL01237-MONOMER - HAMAP: MF_00183 - InterPro: IPR003821 - InterPro: IPR013644 - InterPro: IPR013512 - InterPro: IPR016040 - Gene3D: G3DSA:3.40.50.720 - PIRSF: PIRSF006205 - TIGRFAMs: TIGR00243
Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom
EC number: =1.1.1.267
Molecular weight: Translated: 42594; Mature: 42594
Theoretical pI: Translated: 5.86; Mature: 5.86
Prosite motif: NA
Important sites: BINDING 123-123 BINDING 150-150 BINDING 174-174 BINDING 197-197 BINDING 219-219
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNICLLGATGSIGEQTLDVIKAHDDKFRLTAMTFGKNAEKAAEIIETFKPKYVGVGDEH CCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEECCCCHH TYETLKQHSFSYTFKTGIGEEALIEAAVIPEADIVVNALVGSVGLLPTLKAMEHKKTIAL HHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHEEE ANKETLVTAGHIVKEHAQKYDVPLLPVDSEHSAIFQALQGENPKHIKRLIVTASGGSFRD CCCCCEEHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCHHHEEEEEEEECCCCCHH RTRRELEGVTVEEALNHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDLPYDQIDVLLHK HHHHHHCCCCHHHHHCCCCCCCCCEEEECHHHHHHCCHHHHHHHEEEECCHHHHHHHHHH ESIIHSMVEFHDRSVIAQLGTPDMRVPIQYALSHPERLPFNEAKSLDLWEVGQLNFAQAD HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEECCCCCHHHHH FERFRCLQFAYESGKIGGTMPTVLNAANEEAVAAFLSGRISFLGIEDIIEKALERHQVIA HHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHC KPSLQEIREVDKDARKFVQTLLT CCCHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MKNICLLGATGSIGEQTLDVIKAHDDKFRLTAMTFGKNAEKAAEIIETFKPKYVGVGDEH CCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEECCCCHH TYETLKQHSFSYTFKTGIGEEALIEAAVIPEADIVVNALVGSVGLLPTLKAMEHKKTIAL HHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHEEE ANKETLVTAGHIVKEHAQKYDVPLLPVDSEHSAIFQALQGENPKHIKRLIVTASGGSFRD CCCCCEEHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCHHHEEEEEEEECCCCCHH RTRRELEGVTVEEALNHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDLPYDQIDVLLHK HHHHHHCCCCHHHHHCCCCCCCCCEEEECHHHHHHCCHHHHHHHEEEECCHHHHHHHHHH ESIIHSMVEFHDRSVIAQLGTPDMRVPIQYALSHPERLPFNEAKSLDLWEVGQLNFAQAD HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEECCCCCHHHHH FERFRCLQFAYESGKIGGTMPTVLNAANEEAVAAFLSGRISFLGIEDIIEKALERHQVIA HHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHC KPSLQEIREVDKDARKFVQTLLT CCCHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA