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The map label for this gene is mraY [H]

Identifier: 52785495

GI number: 52785495

Start: 1691647

End: 1692666

Strand: Direct

Name: mraY [H]

Synonym: BLi01736

Alternate gene names: 52785495

Gene position: 1691647-1692666 (Clockwise)

Preceding gene: 52785494

Following gene: 52785496

Centisome position: 40.06

GC content: 47.65

Gene sequence:

>1020_bases
ATGCGTATGCTGCTTCTTATATCATGCGGAAAGGAGAGAAGAACGATGCTCGAACAAGTAATTTTATTTACCATTATCAT
GGGCTTTTTAATCAGCGTTCTTTTATCTCCGATTTTCATTCCGTTTTTAAGAAGGCTGAAATTCGGGCAGAGCATCCGTG
AGGAAGGTCCGAAATCCCATCAGAAAAAATCGGGAACGCCGACGATGGGCGGCGTCATGATCATATTGTCGATTATCGCG
ACGACCATTGTTATGACGATGAAATTTTCCGAAGTCAGCATGAACATGATCCTCCTCTTGTTTGTTACGGTTGGATACGG
TCTGCTCGGCTTTCTGGATGATTATATTAAAGTCGTGATGAAGCGCAACCTTGGACTCACATCCAAACAAAAACTGATCG
GTCAGATCGTGATTGCTCTCGTATTCTATGCCGTCTACCACTTCCAAGGAATGCCGACTGACATCCGCATTCCGGGAACA
GAGCTGTCGTTTGACTTCGGCTGGATTTATCCAGTGCTCGTCATCTTTATGCTTGTCGGCGGTTCAAATGCCGTCAACCT
GACTGACGGGCTTGACGGTCTGTTGTCGGGTACAGCTGCCATCGCGTTCGGTGCGTTTGCGATTTTGGCGTGGAACCAGT
CGCAATACGATGTCGCAATTTTCGCGGTTGCCGTTGTCGGAGCGGTGTTAGGATTTCTTGTGTTTAACGCGCACCCCGCG
AAAGTCTTTATGGGAGATACAGGGTCGCTTGCCCTCGGCGGCGCGATTGTGACGATCGCGATTTTAACGAAACTGGAAAT
CCTGCTTGTTATCATCGGCGGTGTATTCGTCATTGAAACGCTGTCCGTCATTTTGCAGGTCATTTCATTTAAAACGACCG
GCAAACGAATTTTCAAAATGAGCCCTCTTCACCATCACTACGAGCTTGTCGGATGGTCTGAGTGGAGAGTTGTCGTCACT
TTTTGGACAGCGGGGCTTCTGCTTGCCGTCTTAGGAATTTACATCGAGGTGTGGTTATAA

Upstream 100 bases:

>100_bases
ATTCTTGAGCTGAAATAATCGAAAAAGAACTACAGGAAAGAGTTGTTGAAATGATGGATGAAATAAATCAACATATGAAA
AAAAACAGTGAATATGATAA

Downstream 100 bases:

>100_bases
GTGGATACTCAAGATTTATTGCAAAATCAAAATGTGCTCGTACTGGGGCTGGCGAAAAGCGGATATGCTGCCGCTTCGAT
CCTTCATGAGAAAGGCGTAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRMLLLISCGKERRTMLEQVILFTIIMGFLISVLLSPIFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMIILSIIA
TTIVMTMKFSEVSMNMILLLFVTVGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIVIALVFYAVYHFQGMPTDIRIPGT
ELSFDFGWIYPVLVIFMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFAVAVVGAVLGFLVFNAHPA
KVFMGDTGSLALGGAIVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEWRVVVT
FWTAGLLLAVLGIYIEVWL

Sequences:

>Translated_339_residues
MRMLLLISCGKERRTMLEQVILFTIIMGFLISVLLSPIFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMIILSIIA
TTIVMTMKFSEVSMNMILLLFVTVGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIVIALVFYAVYHFQGMPTDIRIPGT
ELSFDFGWIYPVLVIFMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFAVAVVGAVLGFLVFNAHPA
KVFMGDTGSLALGGAIVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEWRVVVT
FWTAGLLLAVLGIYIEVWL
>Mature_339_residues
MRMLLLISCGKERRTMLEQVILFTIIMGFLISVLLSPIFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMIILSIIA
TTIVMTMKFSEVSMNMILLLFVTVGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIVIALVFYAVYHFQGMPTDIRIPGT
ELSFDFGWIYPVLVIFMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFAVAVVGAVLGFLVFNAHPA
KVFMGDTGSLALGGAIVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEWRVVVT
FWTAGLLLAVLGIYIEVWL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=334, Percent_Identity=44.9101796407186, Blast_Score=244, Evalue=7e-66,
Organism=Escherichia coli, GI1790218, Length=95, Percent_Identity=34.7368421052632, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 37273; Mature: 37273

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLLLISCGKERRTMLEQVILFTIIMGFLISVLLSPIFIPFLRRLKFGQSIREEGPKSH
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHH
QKKSGTPTMGGVMIILSIIATTIVMTMKFSEVSMNMILLLFVTVGYGLLGFLDDYIKVVM
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNLGLTSKQKLIGQIVIALVFYAVYHFQGMPTDIRIPGTELSFDFGWIYPVLVIFMLVG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHC
GSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFAVAVVGAVLGFLVFNAHPA
CCCCEECCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
KVFMGDTGSLALGGAIVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKM
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEE
SPLHHHYELVGWSEWRVVVTFWTAGLLLAVLGIYIEVWL
CCCHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRMLLLISCGKERRTMLEQVILFTIIMGFLISVLLSPIFIPFLRRLKFGQSIREEGPKSH
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHH
QKKSGTPTMGGVMIILSIIATTIVMTMKFSEVSMNMILLLFVTVGYGLLGFLDDYIKVVM
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNLGLTSKQKLIGQIVIALVFYAVYHFQGMPTDIRIPGTELSFDFGWIYPVLVIFMLVG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHC
GSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFAVAVVGAVLGFLVFNAHPA
CCCCEECCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
KVFMGDTGSLALGGAIVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKM
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEE
SPLHHHYELVGWSEWRVVVTFWTAGLLLAVLGIYIEVWL
CCCHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA