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The map label for this gene is ykuA [H]

Identifier: 52785371

GI number: 52785371

Start: 1573324

End: 1575432

Strand: Direct

Name: ykuA [H]

Synonym: BLi01608

Alternate gene names: 52785371

Gene position: 1573324-1575432 (Clockwise)

Preceding gene: 52785369

Following gene: 52785372

Centisome position: 37.26

GC content: 49.6

Gene sequence:

>2109_bases
GTGACAGAATCTCAACATGATCCGGCTGAAATCAAAAAGAGCAGGCGTTCGCGTTTATGGCGGATCAACCTGTACTTCTT
TGCGGTGTTCACTTTGTTCGCTGCGCTGATTGTCAAGCTGGGCCTCGTGCAAATCGTCAATGGAGAGGCGTATGAGCAGG
AAGCTTCGAAAACCGAGGCGAAAATTGCGTCATACCCGGCACCGCGGGGTAAAATGTATGACAGATACGGGCGGGTGGTT
GTCGACAACCAAAGCGTTCCCGCGATCACATATACGATGATGACTAGCACAAAAACGGAGGAAAAAATCAGCACAGCCAA
AAAACTCGCAGAATTGATCGATATCGATACTTCGTTTCTGAAAGAGAGAGATCTGAAAGATTACTGGCTTGCCAGACACC
CGAAAAAAGCTGCTGCACTTCTGAAAGACAGCGAGAAAACCCTCAAGTCTGATCAAACATACAAGCTTCAGGTGGACCGC
GTTCCGGCGGAAGAGATCAAAGCGCTGGAAAAGGACAAAGATGAGCTTAAAGTCGCAGCGATTTTCAGAAGATTTTCTGG
CGGCTATGCGTATGAGCCGCAAATCGTCAAGGCGATGAGCCCGAAAACCGCGGGGAAAAACGATGCGCAGCTCCTTGATG
AGAAGGCTTCTAAACAGATGCCGGCCAACGATTTGACGTATGAGGAAGTCTCACGCGTTTCCGAGCATCTTGAGGAACTG
CCCGGCGTCGACGTCATCATGGACTGGACCAGGAAATATCCTTATGAAAAAACGCTCTACTCCATTTTCGGAGGCGTCAC
AACGCCTGAACAAGGGCTTATCAAGGACCGGGAAGACTTTTACCTGACAAGGGGATATGCCCGGAATGACAGAGTGGGAA
AAAGCTATCTCGAGTATCAATATGAAGAATATTTAAATCCGAAAAAAGCGAAAGTCCAATATACCGAAAACCGTTCAGGA
AAGGTTATCAGCCAGGAAACGGTTGATGAAGGAAGACGCGGCTACGATCTGCAGCTGACGTTCGACATGGAGCTCCAAAA
GAAAGTCGAAGAGGCTATCGAAGAGGAGCTTAATAAATTCCGCGGCTCAAACTACATGCTGGACAGAGCGTTCGTCGTCA
TGATGGACCCGAATAACGGAGACATTCTGTCCATGGCCGGAAAGCGGATCGTCGACGGCAAAATCACCGACTATGCAATC
GGCGCGTTTACAACCCAGTACGAAATGGGATCGGCGGTCAAAGGCGCGACCGTGCTTGCCGGCTATCAGGACGGCATGCC
GCATGGGCAGAGTTATTTAGACCAAGAGCTGAGCTTCGCAGGGGGAGTTAAAAAAGGTTCCTACAGAGGAAACACTATCG
GTTGGGCTAATGAAGTTAGAGCGCTGGAAAAAAGTTCAAACGTTTATATGTTCTATGTGGCAATGAGAATGGCAGGAATT
ACGTATGTACCGAACGGCCCGCTTCCGGCGAACCTAGAGGACTTAAAGAAAATGAGGTATTACTTCAATCAATTTGGCCT
TGGGGTAAAAACAGGCATCGACTTGCCGCAGGAGTCGGCCGGGATGCAGACAAACCCAAAAATAGTCGGGGGTCTCCTCC
TCGATGAAGCGATCGGCCAGTTTGACACGTACACGCCTTTGCAGCTCGCCCAATATGTTTCAACGATCGCCAACGGCGGA
TACAGGTTGCAGCCGAGAGTCGTGAAAAGCATTCACCAGCCAGAAAGCGAAAAACTCGGTCCGGTCATTGAAGAGCGCTC
TGCCAATGTGCTGAATCGTATCAACAATTCTCAAAGCGACATCGCCATCGTCAAGCAAGGATTTAAACGAGTAACCCAGA
CGGGAACTGCAGCCGGCGCATTCGGTTCGCTTGACGTATCAGGCAAAACCGGAACGGCGCAGACGCAATACTACGGCACA
AACCGAAACTGGTGGGGGACTAGGACTTACAATATCACCTTTGCCGGCTATTACCCGTCGGAAAATCCGCAGGTCGCCTT
CAGCGTTGTCGTCCCGAATGTCGACGACAAAACGAAGATGAACAAAAACATCGCCGCCAAAATCGTCAAAGCCTATGTCG
ATCTGCAAAAAAAATACAGCAAAGATTAG

Upstream 100 bases:

>100_bases
TTTTGAAAACTTTAGATTGTAACAACCATTACAAAAGTGTTACAATATATCTCAGTTAATTAATGTAAAATTGAATATTG
TGAGAGGAGAGAGAGTTTCA

Downstream 100 bases:

>100_bases
ACAAAAAAGAACACGGATTTTTTCCGGGTTCTTTTTTTGTTATCAAAATTTGACGAATGCTAGAAGTTTTGAAGGAGATT
TCTCGCATTTTAGCGAATCC

Product: YkuA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MTESQHDPAEIKKSRRSRLWRINLYFFAVFTLFAALIVKLGLVQIVNGEAYEQEASKTEAKIASYPAPRGKMYDRYGRVV
VDNQSVPAITYTMMTSTKTEEKISTAKKLAELIDIDTSFLKERDLKDYWLARHPKKAAALLKDSEKTLKSDQTYKLQVDR
VPAEEIKALEKDKDELKVAAIFRRFSGGYAYEPQIVKAMSPKTAGKNDAQLLDEKASKQMPANDLTYEEVSRVSEHLEEL
PGVDVIMDWTRKYPYEKTLYSIFGGVTTPEQGLIKDREDFYLTRGYARNDRVGKSYLEYQYEEYLNPKKAKVQYTENRSG
KVISQETVDEGRRGYDLQLTFDMELQKKVEEAIEEELNKFRGSNYMLDRAFVVMMDPNNGDILSMAGKRIVDGKITDYAI
GAFTTQYEMGSAVKGATVLAGYQDGMPHGQSYLDQELSFAGGVKKGSYRGNTIGWANEVRALEKSSNVYMFYVAMRMAGI
TYVPNGPLPANLEDLKKMRYYFNQFGLGVKTGIDLPQESAGMQTNPKIVGGLLLDEAIGQFDTYTPLQLAQYVSTIANGG
YRLQPRVVKSIHQPESEKLGPVIEERSANVLNRINNSQSDIAIVKQGFKRVTQTGTAAGAFGSLDVSGKTGTAQTQYYGT
NRNWWGTRTYNITFAGYYPSENPQVAFSVVVPNVDDKTKMNKNIAAKIVKAYVDLQKKYSKD

Sequences:

>Translated_702_residues
MTESQHDPAEIKKSRRSRLWRINLYFFAVFTLFAALIVKLGLVQIVNGEAYEQEASKTEAKIASYPAPRGKMYDRYGRVV
VDNQSVPAITYTMMTSTKTEEKISTAKKLAELIDIDTSFLKERDLKDYWLARHPKKAAALLKDSEKTLKSDQTYKLQVDR
VPAEEIKALEKDKDELKVAAIFRRFSGGYAYEPQIVKAMSPKTAGKNDAQLLDEKASKQMPANDLTYEEVSRVSEHLEEL
PGVDVIMDWTRKYPYEKTLYSIFGGVTTPEQGLIKDREDFYLTRGYARNDRVGKSYLEYQYEEYLNPKKAKVQYTENRSG
KVISQETVDEGRRGYDLQLTFDMELQKKVEEAIEEELNKFRGSNYMLDRAFVVMMDPNNGDILSMAGKRIVDGKITDYAI
GAFTTQYEMGSAVKGATVLAGYQDGMPHGQSYLDQELSFAGGVKKGSYRGNTIGWANEVRALEKSSNVYMFYVAMRMAGI
TYVPNGPLPANLEDLKKMRYYFNQFGLGVKTGIDLPQESAGMQTNPKIVGGLLLDEAIGQFDTYTPLQLAQYVSTIANGG
YRLQPRVVKSIHQPESEKLGPVIEERSANVLNRINNSQSDIAIVKQGFKRVTQTGTAAGAFGSLDVSGKTGTAQTQYYGT
NRNWWGTRTYNITFAGYYPSENPQVAFSVVVPNVDDKTKMNKNIAAKIVKAYVDLQKKYSKD
>Mature_701_residues
TESQHDPAEIKKSRRSRLWRINLYFFAVFTLFAALIVKLGLVQIVNGEAYEQEASKTEAKIASYPAPRGKMYDRYGRVVV
DNQSVPAITYTMMTSTKTEEKISTAKKLAELIDIDTSFLKERDLKDYWLARHPKKAAALLKDSEKTLKSDQTYKLQVDRV
PAEEIKALEKDKDELKVAAIFRRFSGGYAYEPQIVKAMSPKTAGKNDAQLLDEKASKQMPANDLTYEEVSRVSEHLEELP
GVDVIMDWTRKYPYEKTLYSIFGGVTTPEQGLIKDREDFYLTRGYARNDRVGKSYLEYQYEEYLNPKKAKVQYTENRSGK
VISQETVDEGRRGYDLQLTFDMELQKKVEEAIEEELNKFRGSNYMLDRAFVVMMDPNNGDILSMAGKRIVDGKITDYAIG
AFTTQYEMGSAVKGATVLAGYQDGMPHGQSYLDQELSFAGGVKKGSYRGNTIGWANEVRALEKSSNVYMFYVAMRMAGIT
YVPNGPLPANLEDLKKMRYYFNQFGLGVKTGIDLPQESAGMQTNPKIVGGLLLDEAIGQFDTYTPLQLAQYVSTIANGGY
RLQPRVVKSIHQPESEKLGPVIEERSANVLNRINNSQSDIAIVKQGFKRVTQTGTAAGAFGSLDVSGKTGTAQTQYYGTN
RNWWGTRTYNITFAGYYPSENPQVAFSVVVPNVDDKTKMNKNIAAKIVKAYVDLQKKYSKD

Specific function: Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 79084; Mature: 78952

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESQHDPAEIKKSRRSRLWRINLYFFAVFTLFAALIVKLGLVQIVNGEAYEQEASKTEA
CCCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHH
KIASYPAPRGKMYDRYGRVVVDNQSVPAITYTMMTSTKTEEKISTAKKLAELIDIDTSFL
HHHCCCCCCCCHHHHCCCEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHH
KERDLKDYWLARHPKKAAALLKDSEKTLKSDQTYKLQVDRVPAEEIKALEKDKDELKVAA
HHCCCHHHHHHCCCHHHHHHHHCCHHHHCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHH
IFRRFSGGYAYEPQIVKAMSPKTAGKNDAQLLDEKASKQMPANDLTYEEVSRVSEHLEEL
HHHHHCCCCEECCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
PGVDVIMDWTRKYPYEKTLYSIFGGVTTPEQGLIKDREDFYLTRGYARNDRVGKSYLEYQ
CCCEEEHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHH
YEEYLNPKKAKVQYTENRSGKVISQETVDEGRRGYDLQLTFDMELQKKVEEAIEEELNKF
HHHHCCCCCEEEEEECCCCCCEEEHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
RGSNYMLDRAFVVMMDPNNGDILSMAGKRIVDGKITDYAIGAFTTQYEMGSAVKGATVLA
CCCCEEEEEEEEEEECCCCCCEEECCCCEEECCCCCCEEEEHEEEHHHCCCCCCCCEEEE
GYQDGMPHGQSYLDQELSFAGGVKKGSYRGNTIGWANEVRALEKSSNVYMFYVAMRMAGI
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEHHHCCE
TYVPNGPLPANLEDLKKMRYYFNQFGLGVKTGIDLPQESAGMQTNPKIVGGLLLDEAIGQ
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
FDTYTPLQLAQYVSTIANGGYRLQPRVVKSIHQPESEKLGPVIEERSANVLNRINNSQSD
CCCCCHHHHHHHHHHHHCCCEEECHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCCHH
IAIVKQGFKRVTQTGTAAGAFGSLDVSGKTGTAQTQYYGTNRNWWGTRTYNITFAGYYPS
HHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCEEEEEEEEEEECCC
ENPQVAFSVVVPNVDDKTKMNKNIAAKIVKAYVDLQKKYSKD
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TESQHDPAEIKKSRRSRLWRINLYFFAVFTLFAALIVKLGLVQIVNGEAYEQEASKTEA
CCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHH
KIASYPAPRGKMYDRYGRVVVDNQSVPAITYTMMTSTKTEEKISTAKKLAELIDIDTSFL
HHHCCCCCCCCHHHHCCCEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHH
KERDLKDYWLARHPKKAAALLKDSEKTLKSDQTYKLQVDRVPAEEIKALEKDKDELKVAA
HHCCCHHHHHHCCCHHHHHHHHCCHHHHCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHH
IFRRFSGGYAYEPQIVKAMSPKTAGKNDAQLLDEKASKQMPANDLTYEEVSRVSEHLEEL
HHHHHCCCCEECCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
PGVDVIMDWTRKYPYEKTLYSIFGGVTTPEQGLIKDREDFYLTRGYARNDRVGKSYLEYQ
CCCEEEHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHH
YEEYLNPKKAKVQYTENRSGKVISQETVDEGRRGYDLQLTFDMELQKKVEEAIEEELNKF
HHHHCCCCCEEEEEECCCCCCEEEHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
RGSNYMLDRAFVVMMDPNNGDILSMAGKRIVDGKITDYAIGAFTTQYEMGSAVKGATVLA
CCCCEEEEEEEEEEECCCCCCEEECCCCEEECCCCCCEEEEHEEEHHHCCCCCCCCEEEE
GYQDGMPHGQSYLDQELSFAGGVKKGSYRGNTIGWANEVRALEKSSNVYMFYVAMRMAGI
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEHHHCCE
TYVPNGPLPANLEDLKKMRYYFNQFGLGVKTGIDLPQESAGMQTNPKIVGGLLLDEAIGQ
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
FDTYTPLQLAQYVSTIANGGYRLQPRVVKSIHQPESEKLGPVIEERSANVLNRINNSQSD
CCCCCHHHHHHHHHHHHCCCEEECHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCCHH
IAIVKQGFKRVTQTGTAAGAFGSLDVSGKTGTAQTQYYGTNRNWWGTRTYNITFAGYYPS
HHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCEEEEEEEEEEECCC
ENPQVAFSVVVPNVDDKTKMNKNIAAKIVKAYVDLQKKYSKD
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]