Click here to switch to the map view.

The map label for this gene is kinA [H]

Identifier: 52785372

GI number: 52785372

Start: 1575593

End: 1577404

Strand: Direct

Name: kinA [H]

Synonym: BLi01609

Alternate gene names: 52785372

Gene position: 1575593-1577404 (Clockwise)

Preceding gene: 52785371

Following gene: 52785374

Centisome position: 37.31

GC content: 44.59

Gene sequence:

>1812_bases
ATGGAACAAAAAACAAAACGTTTTGAGCAATATAAGCCTCATATGAATTTACAGGCAGTCCTGTCAGCTAACGGCCGTTT
TATATACATATCTGCAAATTGCAAAGAGCTCTTAAGCTACGAGCAGAATGAACTGATCGGTACGTATTTGAAGGACTATT
TACACGAAGACGATCTTTTTCTGGTAGAAAGCTATTTTTACAATGAGCATCATTTGCTGCCCTGCACCTTCAGATTTGTG
AAAAAAGACTACACGATGATCTGGATCGAAGCATCGATCGATTTCGTGACGACCCATGTTGGAGAAAAAGAACGCGAAAT
TGTACTCAAAATGAAAGTGTTTGAAGACCGTCCCTCTAAGAAAAGCAGCTCCATAAAAGAGGAAGACGCTCCGGAAGAAG
CCTCCAGGCTGCCGGCAAAAGAGGAATTCGAAGCCATGATCGAAGGCTTGCCAAACCCTCTGTGCATCAGCGTTCAAGGG
GAAATAGTCTACGTAAATGACGCCATGGTCAACCTGCTCGGAGCCGAGCATAAACGGCAAATTATCGGAAAGTATTCCTA
CGATTTTATCGAGAAAGAGTACCATGACATCGTCAAAAACCGCATTAAGCGGATGCAGCAGGGACTTGATGTCGGAATGA
TCGAGCAAACGTGGCATAAGCTCGACGGCACGCAGATTCACCTCGAAGTCAAGGCGGCGCCGACCATTTATCAAAACCAG
AAAGCGGAGCTGCTTCTTCTCATTGACATTTCATCGAGAAAAAAATTTCAGACCATTTTGCAAAAAAGCAGGGAGCGATA
TCAGCTCTTGATTCAAAACTCAATCGATACGATAGCCGTGATTCATAAAGGAAGATGGGTCTTTATGAATGAATCGGGCA
TTCGTCTGTTTGAAGCAAAGACGTATGAGGATTTAATCGGCAAAGATATTTACGAACACCTGCACCCATGCGATCACGAA
GATGTCAAAGCGAGGCTGAAACGGATCACAGACCGCCAATCCGAATCTGAAATCATAAAACAGACGTGGTATACATTTGA
AAAAAGGCTCATCTATACAGAAATGGTTTGCATCCCTACGACATTTTTCGGGGAAACGGCGGTTCAGGTGATTTTAAGGG
ACATTTCTGAACGCAAGCAGACCGAAGAGCTGATGGTCCGTTCGGAAAAGCTGTCGATTGCCGGACAGCTTGCAGCCGGG
ATCGCCCATGAAATCCGCAATCCGCTCACCGCGATCAAAGGGTTTTTGCAGCTGATGAAGCCGACAATGGAAGAAAATGA
ACATTATTTTAATATTATCTTTTCCGAGTTAAGCAGAATCGAATTGATCTTGAGCGAGCTTCTCATGCTGGCAAAGCCGC
AGCAAAACGCATTGAAAGAAAAGCTTGATCTGATCAGGCTGATCCGCGAAGTGACGGCGCTTTTAGAAACGCAGGCCAAC
TTAAACGGCATTTTGATCAATACGATCCTCACAGACGACAAAATTTACATTAAAGGGGATCAAAATCAATTAAAGCAAGT
GTTTATCAACCTAATCAAAAACGCCGTCGAATCCATGCCAAACGGCGGGACGGTTCATTTGACGGTCAGAGAAACCGACG
ATTCGGTCGTCGTCGAGGTGGAGGACGAAGGAGAAGGGATACCTGAACATGTCCTGAAGCGGATCGGCGAGCCGTTTTTG
ACGACGAAGGAAAAAGGAACAGGCCTCGGTTTGATGGTCACCTTCAATATCATCGAAAATCACAACGGAACCATCGAAGT
CGACAGCAAAGCAGAAAAAGGCACGACATTTAAGATTCTATTTCCAAAATAA

Upstream 100 bases:

>100_bases
TAGAAGTTTTGAAGGAGATTTCTCGCATTTTAGCGAATCCTTTTAAGCAAAATAGTTTTAATGAATGCTGGTCATGAATA
GGGTATAAAGGAGGGATATG

Downstream 100 bases:

>100_bases
AATAAAAAAACAACGGCGTAAAAGCCGTTGTTTACGTAGTCTGTATCGATTGCCTCTTATTGAAAACAAAGGACTCCAGC
CGGTCAAGACCTTCCCTTAG

Product: KinA

Products: NA

Alternate protein names: Stage II sporulation protein F; Stage II sporulation protein J [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MEQKTKRFEQYKPHMNLQAVLSANGRFIYISANCKELLSYEQNELIGTYLKDYLHEDDLFLVESYFYNEHHLLPCTFRFV
KKDYTMIWIEASIDFVTTHVGEKEREIVLKMKVFEDRPSKKSSSIKEEDAPEEASRLPAKEEFEAMIEGLPNPLCISVQG
EIVYVNDAMVNLLGAEHKRQIIGKYSYDFIEKEYHDIVKNRIKRMQQGLDVGMIEQTWHKLDGTQIHLEVKAAPTIYQNQ
KAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHKGRWVFMNESGIRLFEAKTYEDLIGKDIYEHLHPCDHE
DVKARLKRITDRQSESEIIKQTWYTFEKRLIYTEMVCIPTTFFGETAVQVILRDISERKQTEELMVRSEKLSIAGQLAAG
IAHEIRNPLTAIKGFLQLMKPTMEENEHYFNIIFSELSRIELILSELLMLAKPQQNALKEKLDLIRLIREVTALLETQAN
LNGILINTILTDDKIYIKGDQNQLKQVFINLIKNAVESMPNGGTVHLTVRETDDSVVVEVEDEGEGIPEHVLKRIGEPFL
TTKEKGTGLGLMVTFNIIENHNGTIEVDSKAEKGTTFKILFPK

Sequences:

>Translated_603_residues
MEQKTKRFEQYKPHMNLQAVLSANGRFIYISANCKELLSYEQNELIGTYLKDYLHEDDLFLVESYFYNEHHLLPCTFRFV
KKDYTMIWIEASIDFVTTHVGEKEREIVLKMKVFEDRPSKKSSSIKEEDAPEEASRLPAKEEFEAMIEGLPNPLCISVQG
EIVYVNDAMVNLLGAEHKRQIIGKYSYDFIEKEYHDIVKNRIKRMQQGLDVGMIEQTWHKLDGTQIHLEVKAAPTIYQNQ
KAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHKGRWVFMNESGIRLFEAKTYEDLIGKDIYEHLHPCDHE
DVKARLKRITDRQSESEIIKQTWYTFEKRLIYTEMVCIPTTFFGETAVQVILRDISERKQTEELMVRSEKLSIAGQLAAG
IAHEIRNPLTAIKGFLQLMKPTMEENEHYFNIIFSELSRIELILSELLMLAKPQQNALKEKLDLIRLIREVTALLETQAN
LNGILINTILTDDKIYIKGDQNQLKQVFINLIKNAVESMPNGGTVHLTVRETDDSVVVEVEDEGEGIPEHVLKRIGEPFL
TTKEKGTGLGLMVTFNIIENHNGTIEVDSKAEKGTTFKILFPK
>Mature_603_residues
MEQKTKRFEQYKPHMNLQAVLSANGRFIYISANCKELLSYEQNELIGTYLKDYLHEDDLFLVESYFYNEHHLLPCTFRFV
KKDYTMIWIEASIDFVTTHVGEKEREIVLKMKVFEDRPSKKSSSIKEEDAPEEASRLPAKEEFEAMIEGLPNPLCISVQG
EIVYVNDAMVNLLGAEHKRQIIGKYSYDFIEKEYHDIVKNRIKRMQQGLDVGMIEQTWHKLDGTQIHLEVKAAPTIYQNQ
KAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHKGRWVFMNESGIRLFEAKTYEDLIGKDIYEHLHPCDHE
DVKARLKRITDRQSESEIIKQTWYTFEKRLIYTEMVCIPTTFFGETAVQVILRDISERKQTEELMVRSEKLSIAGQLAAG
IAHEIRNPLTAIKGFLQLMKPTMEENEHYFNIIFSELSRIELILSELLMLAKPQQNALKEKLDLIRLIREVTALLETQAN
LNGILINTILTDDKIYIKGDQNQLKQVFINLIKNAVESMPNGGTVHLTVRETDDSVVVEVEDEGEGIPEHVLKRIGEPFL
TTKEKGTGLGLMVTFNIIENHNGTIEVDSKAEKGTTFKILFPK

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=38.6266094420601, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=33.8983050847458, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=27.3858921161826, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=29.5454545454545, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=220, Percent_Identity=30, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=28.3950617283951, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=214, Percent_Identity=25.7009345794392, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=298, Percent_Identity=26.510067114094, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=26.5060240963855, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790551, Length=208, Percent_Identity=27.8846153846154, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=25.3393665158371, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=214, Percent_Identity=27.5700934579439, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=25.3275109170306, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789808, Length=210, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=218, Percent_Identity=27.5229357798165, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=24.3478260869565, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69775; Mature: 69775

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQKTKRFEQYKPHMNLQAVLSANGRFIYISANCKELLSYEQNELIGTYLKDYLHEDDLF
CCCHHHHHHHHCCCCCEEEEEECCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHCCCCEE
LVESYFYNEHHLLPCTFRFVKKDYTMIWIEASIDFVTTHVGEKEREIVLKMKVFEDRPSK
EEEEEECCCCCCCHHHHHHHHCCCEEEEEEECCEEEEECCCCCCHHEEEEEEECCCCCCC
KSSSIKEEDAPEEASRLPAKEEFEAMIEGLPNPLCISVQGEIVYVNDAMVNLLGAEHKRQ
CCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCEEEEEECCEEEECHHHHHHHCCHHHHH
IIGKYSYDFIEKEYHDIVKNRIKRMQQGLDVGMIEQTWHKLDGTQIHLEVKAAPTIYQNQ
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEEECCCEECCC
KAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHKGRWVFMNESGIRLFEAK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCEEEECC
TYEDLIGKDIYEHLHPCDHEDVKARLKRITDRQSESEIIKQTWYTFEKRLIYTEMVCIPT
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
TFFGETAVQVILRDISERKQTEELMVRSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTMEENEHYFNIIFSELSRIELILSELLMLAKPQQNALKEKLDLIRLIREVTALLETQAN
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LNGILINTILTDDKIYIKGDQNQLKQVFINLIKNAVESMPNGGTVHLTVRETDDSVVVEV
CCEEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEE
EDEGEGIPEHVLKRIGEPFLTTKEKGTGLGLMVTFNIIENHNGTIEVDSKAEKGTTFKIL
CCCCCCCHHHHHHHCCCCCEECCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCEEEEE
FPK
CCC
>Mature Secondary Structure
MEQKTKRFEQYKPHMNLQAVLSANGRFIYISANCKELLSYEQNELIGTYLKDYLHEDDLF
CCCHHHHHHHHCCCCCEEEEEECCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHCCCCEE
LVESYFYNEHHLLPCTFRFVKKDYTMIWIEASIDFVTTHVGEKEREIVLKMKVFEDRPSK
EEEEEECCCCCCCHHHHHHHHCCCEEEEEEECCEEEEECCCCCCHHEEEEEEECCCCCCC
KSSSIKEEDAPEEASRLPAKEEFEAMIEGLPNPLCISVQGEIVYVNDAMVNLLGAEHKRQ
CCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCEEEEEECCEEEECHHHHHHHCCHHHHH
IIGKYSYDFIEKEYHDIVKNRIKRMQQGLDVGMIEQTWHKLDGTQIHLEVKAAPTIYQNQ
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEEECCCEECCC
KAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHKGRWVFMNESGIRLFEAK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCEEEECC
TYEDLIGKDIYEHLHPCDHEDVKARLKRITDRQSESEIIKQTWYTFEKRLIYTEMVCIPT
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
TFFGETAVQVILRDISERKQTEELMVRSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTMEENEHYFNIIFSELSRIELILSELLMLAKPQQNALKEKLDLIRLIREVTALLETQAN
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LNGILINTILTDDKIYIKGDQNQLKQVFINLIKNAVESMPNGGTVHLTVRETDDSVVVEV
CCEEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEE
EDEGEGIPEHVLKRIGEPFLTTKEKGTGLGLMVTFNIIENHNGTIEVDSKAEKGTTFKIL
CCCCCCCHHHHHHHCCCCCEECCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCEEEEE
FPK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104615; 2509430; 9384377 [H]