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The map label for this gene is appB [H]

Identifier: 52784999

GI number: 52784999

Start: 1237850

End: 1238800

Strand: Direct

Name: appB [H]

Synonym: BLi01227

Alternate gene names: 52784999

Gene position: 1237850-1238800 (Clockwise)

Preceding gene: 52784998

Following gene: 52785000

Centisome position: 29.31

GC content: 43.95

Gene sequence:

>951_bases
ATGATTACATATATCATTCGAAGGACGCTCATGTCGATTCCAATATTATTTGGTATTACAATTTTGTCATTTGCGATTAT
GAAAGCAGCGCCGGGAGATCCAATGGCATTGATGATGGATCCGACCATCAGCGCGGGAGACCGTGAAAAATTCATTGAAA
AATACGGGTTGGATGAACCTGAACACGTTCAATATTTAAAGTGGCTCGGAAATATGGTTCAAGGTGACTTCGGTACTTCA
ATCGTTAGAAAAGGAACGCCAGTGACTGATTTGATTATGGCGAGGCTGCCGAATACGTTATTGTTAATGCTCGTTTCAAC
CATTTTGGCTCTCCTCATATCGATCCCGCTTGGAGTGCTTTCAGCTAGGCGGCCATATTCTAAATTGGATTATGGCATCA
CATTCACATCATTTATCGGTCTTGCTGTCCCAAATTTTTGGCTTGGACTGATTCTAATCATGTTTCTTGCTGTTAATTTA
GGATGGTTTCCAACCGGGGGCGTTATGACTCTGAATGCCGATTTTAGTTTATGGGATCGCATTCATCATCTAATTTTGCC
TGCATTCGTCCTGGCGACCGCAGATATGGCGGGACTCACCCGCTACACGAGATCGAGCATGCTTGATGTGCTCAGGCAAG
ACTACATGCGGACAGCGAGAGCAAAGGGTTTTAAAGAAAATCGTGTCGTGTACAAGCATGGGCTTCGAAATGGTTTGCTT
CCGGTTATTACGATCTTTGGTCTGATGATTCCTTCTTTCATCGGCGGAGCTGTCGTTACTGAACAGATTTTCAGTTGGCC
AGGACTTGGAAAGCTGTTTGTCGACTCTGCTTTCCAGAGGGACTATCCTGTCATTATGGCAATGACGGTTATTTCAGCCA
CACTTGTTGTCATTGGGAATTTAGTTGCGGATATTCTTTATGCAATGGTCGATCCGCGGATTGAGTATTAA

Upstream 100 bases:

>100_bases
CTGGTGGCTGGATCAAAAATAACGAGAATCCCTTGAGGGAAGTGTAGCTTGCAGCTTCCTTCCCTTCCTTCTTAATGACT
TTTAAAAAAGGGGATAAAAA

Downstream 100 bases:

>100_bases
TGAAGGAGGGAATTGATTCATGACACAGACAAATCCATCGACACCTTCGCCGGAGATCACATTGCAGGAAAATGTCGCAC
CAAAGCCCGAGACAATGACA

Product: AppB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MITYIIRRTLMSIPILFGITILSFAIMKAAPGDPMALMMDPTISAGDREKFIEKYGLDEPEHVQYLKWLGNMVQGDFGTS
IVRKGTPVTDLIMARLPNTLLLMLVSTILALLISIPLGVLSARRPYSKLDYGITFTSFIGLAVPNFWLGLILIMFLAVNL
GWFPTGGVMTLNADFSLWDRIHHLILPAFVLATADMAGLTRYTRSSMLDVLRQDYMRTARAKGFKENRVVYKHGLRNGLL
PVITIFGLMIPSFIGGAVVTEQIFSWPGLGKLFVDSAFQRDYPVIMAMTVISATLVVIGNLVADILYAMVDPRIEY

Sequences:

>Translated_316_residues
MITYIIRRTLMSIPILFGITILSFAIMKAAPGDPMALMMDPTISAGDREKFIEKYGLDEPEHVQYLKWLGNMVQGDFGTS
IVRKGTPVTDLIMARLPNTLLLMLVSTILALLISIPLGVLSARRPYSKLDYGITFTSFIGLAVPNFWLGLILIMFLAVNL
GWFPTGGVMTLNADFSLWDRIHHLILPAFVLATADMAGLTRYTRSSMLDVLRQDYMRTARAKGFKENRVVYKHGLRNGLL
PVITIFGLMIPSFIGGAVVTEQIFSWPGLGKLFVDSAFQRDYPVIMAMTVISATLVVIGNLVADILYAMVDPRIEY
>Mature_316_residues
MITYIIRRTLMSIPILFGITILSFAIMKAAPGDPMALMMDPTISAGDREKFIEKYGLDEPEHVQYLKWLGNMVQGDFGTS
IVRKGTPVTDLIMARLPNTLLLMLVSTILALLISIPLGVLSARRPYSKLDYGITFTSFIGLAVPNFWLGLILIMFLAVNL
GWFPTGGVMTLNADFSLWDRIHHLILPAFVLATADMAGLTRYTRSSMLDVLRQDYMRTARAKGFKENRVVYKHGLRNGLL
PVITIFGLMIPSFIGGAVVTEQIFSWPGLGKLFVDSAFQRDYPVIMAMTVISATLVVIGNLVADILYAMVDPRIEY

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=319, Percent_Identity=41.3793103448276, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=37.8698224852071, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1787497, Length=321, Percent_Identity=34.5794392523364, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789888, Length=322, Percent_Identity=36.9565217391304, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=33.4254143646409, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=36.3914373088685, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=30.8550185873606, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35162; Mature: 35162

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITYIIRRTLMSIPILFGITILSFAIMKAAPGDPMALMMDPTISAGDREKFIEKYGLDEP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCH
EHVQYLKWLGNMVQGDFGTSIVRKGTPVTDLIMARLPNTLLLMLVSTILALLISIPLGVL
HHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SARRPYSKLDYGITFTSFIGLAVPNFWLGLILIMFLAVNLGWFPTGGVMTLNADFSLWDR
HCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHH
IHHLILPAFVLATADMAGLTRYTRSSMLDVLRQDYMRTARAKGFKENRVVYKHGLRNGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHH
PVITIFGLMIPSFIGGAVVTEQIFSWPGLGKLFVDSAFQRDYPVIMAMTVISATLVVIGN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVADILYAMVDPRIEY
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MITYIIRRTLMSIPILFGITILSFAIMKAAPGDPMALMMDPTISAGDREKFIEKYGLDEP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCH
EHVQYLKWLGNMVQGDFGTSIVRKGTPVTDLIMARLPNTLLLMLVSTILALLISIPLGVL
HHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SARRPYSKLDYGITFTSFIGLAVPNFWLGLILIMFLAVNLGWFPTGGVMTLNADFSLWDR
HCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHH
IHHLILPAFVLATADMAGLTRYTRSSMLDVLRQDYMRTARAKGFKENRVVYKHGLRNGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHH
PVITIFGLMIPSFIGGAVVTEQIFSWPGLGKLFVDSAFQRDYPVIMAMTVISATLVVIGN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVADILYAMVDPRIEY
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]