Click here to switch to the map view.

The map label for this gene is argJ

Identifier: 52784979

GI number: 52784979

Start: 1217633

End: 1218853

Strand: Direct

Name: argJ

Synonym: BLi01207

Alternate gene names: 52784979

Gene position: 1217633-1218853 (Clockwise)

Preceding gene: 52784978

Following gene: 52784980

Centisome position: 28.84

GC content: 52.17

Gene sequence:

>1221_bases
ATGATTCAGGTGAGTCAAGACAGCATAAAAAAAACAGACGGAAGCGTCGCTTCGCCTAAGGGCTATCTTGCAAAAGGGGT
CCACTGCGGCCTCCGCTATTCAAAAAAGGATCTTGGGATCATCATCAGCTCAAGACCGGCGGTGAGCGCCGCCGTTTATA
CCCAAAGCCACTTTCAGGCTGCGCCGATCAAGGTGACGCAGGAAAGCCTCAAAAAAAGCGCGCATCTCCAAGCCGTCATC
GTCAACAGCGCCAATGCCAACGCATGCACGGGAGAGCAGGGCTTAAAAGATGCTTATGAAATGCGCCGTCAAAGCGCTGA
TATGCTCGGGATCGAGCCGGATCTGGTGGCCGTGTCCTCAACCGGCGTCATCGGCGAATACCTCAATATGGAAAACATCA
CAAAAGGCATCAGCCTTCTCGCCGAGACAGAGCCTGCCGAAGGCGATTTCGAAGAAGCGATCTTAACGACGGACACCGTG
ATCAAACAAACGTGCTATGAACTGATGATCGGCGGCCAAAAAGTGACGATCGGCGGAGCGGCCAAGGGGTCGGGAATGAT
CCACCCGAATATGGCGACGATGCTCGGCTTTGTCACAACAGATGCATGCATCGAAGAAAGCGCGCTGCAAAGGGCTTTAA
GGGAAATCACGGACGTTTCGTTCAACCAGATAACGGTCGACGGCGATACATCGACGAACGATATGGTGCTCGTCATGGCG
AACGGATGCGCCGGAAATGAGCGCCTCCATGAAGAACACGAAGATTGGCCGGTTTTCAAAAAAGGCCTGCAGCTTGTCTG
CACAGACCTCGCCAAACAAATCGCAAGAGACGGGGAAGGGGCGACAAAGCTGATCGAGGTTGAAGTGAACGGCGCGAAAA
GCAATCTTGAAGCGCAAATCATCGCCAAAAAAATCGTCGGCTCAAACCTTGTAAAAACCGCGGTTTACGGAACGGATGCG
AACTGGGGCAGAATCGTTGTCGCAATCGGGGACAGCATGGCTGCTGTGACACCGGAGAAGGTGGAAATCCGCCTGGGCGG
CCAATGCCTATTTAAAAACAACGAACCCCAGCCGTTTTCGGAAGAGCTGGCCAAAACATATTTAGAAAACAGCGAAGTGA
AAATCGAGGTTTTCATGCAGGAAGGTGAAGGAAAGGGTACGGCTTGGGGCTGCGATTTAACTTATGAATACGTCAAAATC
AATGCGAGCTATCGTACGTAA

Upstream 100 bases:

>100_bases
GGTCAAGCGGTTCAAAACTTCAACATTATGAACGGCTTGAGCGAAACCGCCGGGCTTGAATTTACGCCAATTTATCCATA
AGACGGGAGAGAACAAACTT

Downstream 100 bases:

>100_bases
AAAAGGGGATCACAATGGGTAAAACAATCGTTTTTAAATGCGGCGGAAGCGTCATCCGCGAACTCTCGGACGAATTTTTT
CAAAACCTGAAAGATCTGAC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MIQVSQDSIKKTDGSVASPKGYLAKGVHCGLRYSKKDLGIIISSRPAVSAAVYTQSHFQAAPIKVTQESLKKSAHLQAVI
VNSANANACTGEQGLKDAYEMRRQSADMLGIEPDLVAVSSTGVIGEYLNMENITKGISLLAETEPAEGDFEEAILTTDTV
IKQTCYELMIGGQKVTIGGAAKGSGMIHPNMATMLGFVTTDACIEESALQRALREITDVSFNQITVDGDTSTNDMVLVMA
NGCAGNERLHEEHEDWPVFKKGLQLVCTDLAKQIARDGEGATKLIEVEVNGAKSNLEAQIIAKKIVGSNLVKTAVYGTDA
NWGRIVVAIGDSMAAVTPEKVEIRLGGQCLFKNNEPQPFSEELAKTYLENSEVKIEVFMQEGEGKGTAWGCDLTYEYVKI
NASYRT

Sequences:

>Translated_406_residues
MIQVSQDSIKKTDGSVASPKGYLAKGVHCGLRYSKKDLGIIISSRPAVSAAVYTQSHFQAAPIKVTQESLKKSAHLQAVI
VNSANANACTGEQGLKDAYEMRRQSADMLGIEPDLVAVSSTGVIGEYLNMENITKGISLLAETEPAEGDFEEAILTTDTV
IKQTCYELMIGGQKVTIGGAAKGSGMIHPNMATMLGFVTTDACIEESALQRALREITDVSFNQITVDGDTSTNDMVLVMA
NGCAGNERLHEEHEDWPVFKKGLQLVCTDLAKQIARDGEGATKLIEVEVNGAKSNLEAQIIAKKIVGSNLVKTAVYGTDA
NWGRIVVAIGDSMAAVTPEKVEIRLGGQCLFKNNEPQPFSEELAKTYLENSEVKIEVFMQEGEGKGTAWGCDLTYEYVKI
NASYRT
>Mature_406_residues
MIQVSQDSIKKTDGSVASPKGYLAKGVHCGLRYSKKDLGIIISSRPAVSAAVYTQSHFQAAPIKVTQESLKKSAHLQAVI
VNSANANACTGEQGLKDAYEMRRQSADMLGIEPDLVAVSSTGVIGEYLNMENITKGISLLAETEPAEGDFEEAILTTDTV
IKQTCYELMIGGQKVTIGGAAKGSGMIHPNMATMLGFVTTDACIEESALQRALREITDVSFNQITVDGDTSTNDMVLVMA
NGCAGNERLHEEHEDWPVFKKGLQLVCTDLAKQIARDGEGATKLIEVEVNGAKSNLEAQIIAKKIVGSNLVKTAVYGTDA
NWGRIVVAIGDSMAAVTPEKVEIRLGGQCLFKNNEPQPFSEELAKTYLENSEVKIEVFMQEGEGKGTAWGCDLTYEYVKI
NASYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=411, Percent_Identity=38.1995133819951, Blast_Score=249, Evalue=6e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_BACLD (Q65LE9)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078407.1
- RefSeq:   YP_090808.1
- ProteinModelPortal:   Q65LE9
- SMR:   Q65LE9
- STRING:   Q65LE9
- MEROPS:   T05.001
- EnsemblBacteria:   EBBACT00000055848
- EnsemblBacteria:   EBBACT00000062283
- GeneID:   3030196
- GeneID:   3100753
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01207
- KEGG:   bli:BL03242
- NMPDR:   fig|279010.5.peg.2288
- eggNOG:   COG1364
- GeneTree:   EBGT00050000002382
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BioCyc:   BLIC279010-1:BLI01207-MONOMER
- BioCyc:   BLIC279010:BL03242-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 43714; Mature: 43714

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQVSQDSIKKTDGSVASPKGYLAKGVHCGLRYSKKDLGIIISSRPAVSAAVYTQSHFQA
CEECCCHHHHHCCCCCCCCCCHHHCCEEECCEECCCCCEEEEECCCCCEEEEEECCCCCC
APIKVTQESLKKSAHLQAVIVNSANANACTGEQGLKDAYEMRRQSADMLGIEPDLVAVSS
CCEEEEHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEC
TGVIGEYLNMENITKGISLLAETEPAEGDFEEAILTTDTVIKQTCYELMIGGQKVTIGGA
CCCHHHHHCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
AKGSGMIHPNMATMLGFVTTDACIEESALQRALREITDVSFNQITVDGDTSTNDMVLVMA
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEE
NGCAGNERLHEEHEDWPVFKKGLQLVCTDLAKQIARDGEGATKLIEVEVNGAKSNLEAQI
CCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHH
IAKKIVGSNLVKTAVYGTDANWGRIVVAIGDSMAAVTPEKVEIRLGGQCLFKNNEPQPFS
HHHHHHCCHHHHHEEECCCCCCCEEEEEECCCCEECCCCEEEEEECCEEEECCCCCCCHH
EELAKTYLENSEVKIEVFMQEGEGKGTAWGCDLTYEYVKINASYRT
HHHHHHHHCCCCEEEEEEEECCCCCCCEEECCEEEEEEEEEECCCC
>Mature Secondary Structure
MIQVSQDSIKKTDGSVASPKGYLAKGVHCGLRYSKKDLGIIISSRPAVSAAVYTQSHFQA
CEECCCHHHHHCCCCCCCCCCHHHCCEEECCEECCCCCEEEEECCCCCEEEEEECCCCCC
APIKVTQESLKKSAHLQAVIVNSANANACTGEQGLKDAYEMRRQSADMLGIEPDLVAVSS
CCEEEEHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEC
TGVIGEYLNMENITKGISLLAETEPAEGDFEEAILTTDTVIKQTCYELMIGGQKVTIGGA
CCCHHHHHCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
AKGSGMIHPNMATMLGFVTTDACIEESALQRALREITDVSFNQITVDGDTSTNDMVLVMA
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEE
NGCAGNERLHEEHEDWPVFKKGLQLVCTDLAKQIARDGEGATKLIEVEVNGAKSNLEAQI
CCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHH
IAKKIVGSNLVKTAVYGTDANWGRIVVAIGDSMAAVTPEKVEIRLGGQCLFKNNEPQPFS
HHHHHHCCHHHHHEEECCCCCCCEEEEEECCCCEECCCCEEEEEECCEEEECCCCCCCHH
EELAKTYLENSEVKIEVFMQEGEGKGTAWGCDLTYEYVKINASYRT
HHHHHHHHCCCCEEEEEEEECCCCCCCEEECCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA