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The map label for this gene is argC

Identifier: 52784978

GI number: 52784978

Start: 1216576

End: 1217613

Strand: Direct

Name: argC

Synonym: BLi01206

Alternate gene names: 52784978

Gene position: 1216576-1217613 (Clockwise)

Preceding gene: 52784977

Following gene: 52784979

Centisome position: 28.81

GC content: 46.92

Gene sequence:

>1038_bases
TTGAAAATAGGTATTATAGGTGCTACTGGCTATGGAGGGGCAGAAATCATGAGGATTATGAGGACTCACCCTTATGCAGA
TGAATGCATATTGTATTCATCGAGTGATGAGGGAGCCCGCTATGACGCCGCATACCCGCACCTTGTGAAACTGACAGATC
AACACCTGCAACCGATCGAGGTTAAGAGGATTGCGAATGAAATCGATTTTTTATTTATGGCAGCGCCTCCGGGGATATCC
AGCCGGCTGACGCCACAGTTTGATGCATATGACATACCCATCATTGATCTGTCCGGCGATCTCAGGATACAGAACCCAAG
CGTCTATGAAAAGTGGTATAAAAGGGAAGCCGCGCCTGAACACGTGCTTCAAAAAGCGGTATACGGACTGTCTGAGCTGA
ATCGGGAAGACATTAAAACGGCGCAGTATATAGCCAATCCAGGATGTTTTCCGACAGCGGTTCTTCTCGGCTTGGCGCCG
CTCGTCAAAAGCGGCAGCATCAACGAATCTTTTGTCATCATCGATGCAAAAACAGGGGTATCGGGGGCAGGCAGAAAGCC
GTCGATGGGCACTCATTTTTCAGAGGTCAATGACAATTTTAAAATATACAAGGTAAACGAACACCAGCACACGCCTGAAA
TCGAGCAGACTGTCAAACAGTGGAACTCCGCATTTAAACCGATCACATTCAGCACGCATTTAGTTCCAATGACAAGAGGC
ATTATGGCGACCATCTACACAGAGCTGAAAGACAGCATGGATGCCGAACAGCTGCAGCTTATTTTTTCTAAATTTTATAA
AGATTCATACTTTGTCAGAGTGAGAGAAACGGGTTCGTTCCCTGCCACAAAAGAGGTGTACGGCAGCAATTTTTGCGATA
TCGGCGTTACCGTCGATGAACGGACGAACAGAGTGACAATCGTGTCAGTGATCGATAACTTGATGAAGGGAGCCGCGGGT
CAAGCGGTTCAAAACTTCAACATTATGAACGGCTTGAGCGAAACCGCCGGGCTTGAATTTACGCCAATTTATCCATAA

Upstream 100 bases:

>100_bases
TGAAAGGTGATTGAAAAAATATTAAATATACAATTGAATTAATTTTTATTCATGTTATAATGTTAAATAATTTCACAAAG
ACCAAGAAGGTGAACTCGTT

Downstream 100 bases:

>100_bases
GACGGGAGAGAACAAACTTATGATTCAGGTGAGTCAAGACAGCATAAAAAAAACAGACGGAAGCGTCGCTTCGCCTAAGG
GCTATCTTGCAAAAGGGGTC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKIGIIGATGYGGAEIMRIMRTHPYADECILYSSSDEGARYDAAYPHLVKLTDQHLQPIEVKRIANEIDFLFMAAPPGIS
SRLTPQFDAYDIPIIDLSGDLRIQNPSVYEKWYKREAAPEHVLQKAVYGLSELNREDIKTAQYIANPGCFPTAVLLGLAP
LVKSGSINESFVIIDAKTGVSGAGRKPSMGTHFSEVNDNFKIYKVNEHQHTPEIEQTVKQWNSAFKPITFSTHLVPMTRG
IMATIYTELKDSMDAEQLQLIFSKFYKDSYFVRVRETGSFPATKEVYGSNFCDIGVTVDERTNRVTIVSVIDNLMKGAAG
QAVQNFNIMNGLSETAGLEFTPIYP

Sequences:

>Translated_345_residues
MKIGIIGATGYGGAEIMRIMRTHPYADECILYSSSDEGARYDAAYPHLVKLTDQHLQPIEVKRIANEIDFLFMAAPPGIS
SRLTPQFDAYDIPIIDLSGDLRIQNPSVYEKWYKREAAPEHVLQKAVYGLSELNREDIKTAQYIANPGCFPTAVLLGLAP
LVKSGSINESFVIIDAKTGVSGAGRKPSMGTHFSEVNDNFKIYKVNEHQHTPEIEQTVKQWNSAFKPITFSTHLVPMTRG
IMATIYTELKDSMDAEQLQLIFSKFYKDSYFVRVRETGSFPATKEVYGSNFCDIGVTVDERTNRVTIVSVIDNLMKGAAG
QAVQNFNIMNGLSETAGLEFTPIYP
>Mature_345_residues
MKIGIIGATGYGGAEIMRIMRTHPYADECILYSSSDEGARYDAAYPHLVKLTDQHLQPIEVKRIANEIDFLFMAAPPGIS
SRLTPQFDAYDIPIIDLSGDLRIQNPSVYEKWYKREAAPEHVLQKAVYGLSELNREDIKTAQYIANPGCFPTAVLLGLAP
LVKSGSINESFVIIDAKTGVSGAGRKPSMGTHFSEVNDNFKIYKVNEHQHTPEIEQTVKQWNSAFKPITFSTHLVPMTRG
IMATIYTELKDSMDAEQLQLIFSKFYKDSYFVRVRETGSFPATKEVYGSNFCDIGVTVDERTNRVTIVSVIDNLMKGAAG
QAVQNFNIMNGLSETAGLEFTPIYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=339, Percent_Identity=35.9882005899705, Blast_Score=191, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6320913, Length=342, Percent_Identity=30.1169590643275, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_BACLD (Q65LF0)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078406.1
- RefSeq:   YP_090807.1
- ProteinModelPortal:   Q65LF0
- SMR:   Q65LF0
- STRING:   Q65LF0
- EnsemblBacteria:   EBBACT00000055458
- EnsemblBacteria:   EBBACT00000061718
- GeneID:   3030195
- GeneID:   3098234
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01206
- KEGG:   bli:BL03241
- NMPDR:   fig|279010.5.peg.2287
- eggNOG:   COG0002
- GeneTree:   EBGT00050000002599
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   BLIC279010-1:BLI01206-MONOMER
- BioCyc:   BLIC279010:BL03241-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38412; Mature: 38412

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIIGATGYGGAEIMRIMRTHPYADECILYSSSDEGARYDAAYPHLVKLTDQHLQPIE
CEEEEEEECCCCHHHHHHHHHCCCCCCCEEEECCCCCCCEECCCCCHHHHHHHHCCCCHH
VKRIANEIDFLFMAAPPGISSRLTPQFDAYDIPIIDLSGDLRIQNPSVYEKWYKREAAPE
HHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHCCCHH
HVLQKAVYGLSELNREDIKTAQYIANPGCFPTAVLLGLAPLVKSGSINESFVIIDAKTGV
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
SGAGRKPSMGTHFSEVNDNFKIYKVNEHQHTPEIEQTVKQWNSAFKPITFSTHLVPMTRG
CCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHH
IMATIYTELKDSMDAEQLQLIFSKFYKDSYFVRVRETGSFPATKEVYGSNFCDIGVTVDE
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHCCCCEEEEEEECC
RTNRVTIVSVIDNLMKGAAGQAVQNFNIMNGLSETAGLEFTPIYP
CCCCEEHHHHHHHHHHCCCCHHHHHHHHHHCCHHHCCCEEECCCC
>Mature Secondary Structure
MKIGIIGATGYGGAEIMRIMRTHPYADECILYSSSDEGARYDAAYPHLVKLTDQHLQPIE
CEEEEEEECCCCHHHHHHHHHCCCCCCCEEEECCCCCCCEECCCCCHHHHHHHHCCCCHH
VKRIANEIDFLFMAAPPGISSRLTPQFDAYDIPIIDLSGDLRIQNPSVYEKWYKREAAPE
HHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHCCCHH
HVLQKAVYGLSELNREDIKTAQYIANPGCFPTAVLLGLAPLVKSGSINESFVIIDAKTGV
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
SGAGRKPSMGTHFSEVNDNFKIYKVNEHQHTPEIEQTVKQWNSAFKPITFSTHLVPMTRG
CCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHH
IMATIYTELKDSMDAEQLQLIFSKFYKDSYFVRVRETGSFPATKEVYGSNFCDIGVTVDE
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHCCCCEEEEEEECC
RTNRVTIVSVIDNLMKGAAGQAVQNFNIMNGLSETAGLEFTPIYP
CCCCEEHHHHHHHHHHCCCCHHHHHHHHHHCCHHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA