Click here to switch to the map view.

The map label for this gene is rhbA [H]

Identifier: 52784955

GI number: 52784955

Start: 1191369

End: 1192715

Strand: Direct

Name: rhbA [H]

Synonym: BLi01183

Alternate gene names: 52784955

Gene position: 1191369-1192715 (Clockwise)

Preceding gene: 52784954

Following gene: 52784956

Centisome position: 28.21

GC content: 50.85

Gene sequence:

>1347_bases
ATGCCTGTACAAACGAGTTCTAAAAATCAAGTGTTTTTGGAGCAGCAAAATAGAAGAGAATCTAATGCGCGTTCATATCC
GAGAAGATTTCCGCTCGCCATGCAGACAGCGGAAGGCGTCTTGGTGACTGATGCGGATGGAAAGCAATATTATGACTGTC
TGGCAGGAGCGGGGACGCTTGCGCTTGGTCATAATCATCCAGTTGTGATTGAAGCGATTCAAAAAATGATTGAGGAAAAA
CGCCCGCTGCACACCCTTGATATTACTTCGGAAATCAAAGAGGAGTTTGTCAACGAAGTATTTGCAAGCCTTCCTGAGGC
GTTTGCCAAACGGGCGAAGATACAGTTTTGCGGTCCGACCGGCGGCGATGCGATCGAAGCCGCTCTCAAGCTTGTCAAAA
CGGCGACTGGGAAAAGAACCATCCTATCGTTTCACGGCGCCTACCATGGAGCAACTCACGGAACGATGGCGCTGAGCGGG
AATTTATCTCCTAAGGAAAACGTCCAGGGTCTCATGCCTGATGTGCATTTCCTGCCATATCCGTATGAATACCGCTGCCC
GTTTGGAAAAGGAGGAGAGGCGAGCCACAAGCTGTCGAGCGCATATATCGAAAATATGCTGGATGATCCGGAAAGCGGAG
TTTTACAGCCTGCAGGGATGATCTTTGAAGCCGTACAAGGAGAAGGAGGCTCAGTTCCGGCCCGGGCTGAATGGATAAGA
GAAATGAGAAGGATTACAAAAGAACGCGGAATCCCTCTGATCATTGACGAGGTGCAGACCGGCATCGGCAGAACCGGCAA
AATGTTTGCGTTCGAGCACGCCGGCATTATACCGGATGTCATCGTCCTTTCAAAAGCGATCGGCGGAAGCCTTCCTCTGT
CTGTCGTCATCTATGATCAAGACCTTGATCAGTGGGGACCCGGGGCGCACATCGGCACATTCAGAGGGAATCAGATGGCG
ATGGCGGCCGGAAGTGCAACTTTAAAATATATAAAAGAGCACGATGTGCTATCACATGTAGAAAAGGTCGGAGCGAAGCT
CATGCGGGAATTGCAAGACATTCAGGAGCACGTTCCCGAAATCGGCGATGTCCGGGGACGAGGGCTGATGATCGGCGCCG
AAATTGTCGCACCGCATAAAAAGCAAAACGCAAACGGCAGCTATCCGGCTGATGCGGAGCTTGCAAGCACGATTCAAAGA
AAATGCTTTGAAAAAGGACTGATCGTTGAAACGGGAGGCCGCCACGGAAGCGTGATCCGCTTCTTGCCGCCGCTTATCGT
AACAGAGGCGCAAATCGACGATATCATCACGATCTTCAGAGAGGCCGTCTATGAAGCAGTCAAGTAA

Upstream 100 bases:

>100_bases
TCCTATTTTTCTGAATCTTATTGACATGCCGGTGTCACAAAATATACACTTTTTTTGTAATTGAAAATGATAATCTTTAT
CAATTGGAGGGATGCTTTCT

Downstream 100 bases:

>100_bases
ACAAAAAAACTTTGATTCCCTGTTTATGCACAACGGGGAACAGGGGATCAAAGCATACCGTGACGCGGTAGAGACCGCTG
TAGAGACGCTTTGGGCCGAT

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MPVQTSSKNQVFLEQQNRRESNARSYPRRFPLAMQTAEGVLVTDADGKQYYDCLAGAGTLALGHNHPVVIEAIQKMIEEK
RPLHTLDITSEIKEEFVNEVFASLPEAFAKRAKIQFCGPTGGDAIEAALKLVKTATGKRTILSFHGAYHGATHGTMALSG
NLSPKENVQGLMPDVHFLPYPYEYRCPFGKGGEASHKLSSAYIENMLDDPESGVLQPAGMIFEAVQGEGGSVPARAEWIR
EMRRITKERGIPLIIDEVQTGIGRTGKMFAFEHAGIIPDVIVLSKAIGGSLPLSVVIYDQDLDQWGPGAHIGTFRGNQMA
MAAGSATLKYIKEHDVLSHVEKVGAKLMRELQDIQEHVPEIGDVRGRGLMIGAEIVAPHKKQNANGSYPADAELASTIQR
KCFEKGLIVETGGRHGSVIRFLPPLIVTEAQIDDIITIFREAVYEAVK

Sequences:

>Translated_448_residues
MPVQTSSKNQVFLEQQNRRESNARSYPRRFPLAMQTAEGVLVTDADGKQYYDCLAGAGTLALGHNHPVVIEAIQKMIEEK
RPLHTLDITSEIKEEFVNEVFASLPEAFAKRAKIQFCGPTGGDAIEAALKLVKTATGKRTILSFHGAYHGATHGTMALSG
NLSPKENVQGLMPDVHFLPYPYEYRCPFGKGGEASHKLSSAYIENMLDDPESGVLQPAGMIFEAVQGEGGSVPARAEWIR
EMRRITKERGIPLIIDEVQTGIGRTGKMFAFEHAGIIPDVIVLSKAIGGSLPLSVVIYDQDLDQWGPGAHIGTFRGNQMA
MAAGSATLKYIKEHDVLSHVEKVGAKLMRELQDIQEHVPEIGDVRGRGLMIGAEIVAPHKKQNANGSYPADAELASTIQR
KCFEKGLIVETGGRHGSVIRFLPPLIVTEAQIDDIITIFREAVYEAVK
>Mature_447_residues
PVQTSSKNQVFLEQQNRRESNARSYPRRFPLAMQTAEGVLVTDADGKQYYDCLAGAGTLALGHNHPVVIEAIQKMIEEKR
PLHTLDITSEIKEEFVNEVFASLPEAFAKRAKIQFCGPTGGDAIEAALKLVKTATGKRTILSFHGAYHGATHGTMALSGN
LSPKENVQGLMPDVHFLPYPYEYRCPFGKGGEASHKLSSAYIENMLDDPESGVLQPAGMIFEAVQGEGGSVPARAEWIRE
MRRITKERGIPLIIDEVQTGIGRTGKMFAFEHAGIIPDVIVLSKAIGGSLPLSVVIYDQDLDQWGPGAHIGTFRGNQMAM
AAGSATLKYIKEHDVLSHVEKVGAKLMRELQDIQEHVPEIGDVRGRGLMIGAEIVAPHKKQNANGSYPADAELASTIQRK
CFEKGLIVETGGRHGSVIRFLPPLIVTEAQIDDIITIFREAVYEAVK

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=29.6380090497738, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI37574042, Length=434, Percent_Identity=28.3410138248848, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI226442705, Length=433, Percent_Identity=27.7136258660508, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI4557809, Length=426, Percent_Identity=26.2910798122066, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442709, Length=403, Percent_Identity=28.5359801488834, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24119277, Length=444, Percent_Identity=25, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI284507298, Length=334, Percent_Identity=26.9461077844311, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI188536080, Length=449, Percent_Identity=24.2761692650334, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI38679950, Length=449, Percent_Identity=24.2761692650334, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI38679946, Length=449, Percent_Identity=24.2761692650334, Blast_Score=102, Evalue=1e-21,
Organism=Escherichia coli, GI1789016, Length=432, Percent_Identity=33.7962962962963, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787560, Length=434, Percent_Identity=33.1797235023041, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI145693181, Length=410, Percent_Identity=28.2926829268293, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789759, Length=421, Percent_Identity=29.9287410926366, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1788044, Length=418, Percent_Identity=28.9473684210526, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786991, Length=424, Percent_Identity=26.4150943396226, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=28.4431137724551, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=28.2407407407407, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=460, Percent_Identity=26.5217391304348, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25144271, Length=431, Percent_Identity=27.1461716937355, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25144274, Length=233, Percent_Identity=30.4721030042918, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17541228, Length=443, Percent_Identity=22.7990970654628, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323470, Length=450, Percent_Identity=29.5555555555556, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324432, Length=423, Percent_Identity=29.7872340425532, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6321456, Length=459, Percent_Identity=24.8366013071895, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=464, Percent_Identity=22.4137931034483, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28574759, Length=463, Percent_Identity=27.4298056155508, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI161085790, Length=458, Percent_Identity=27.292576419214, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI21357415, Length=428, Percent_Identity=28.0373831775701, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356575, Length=469, Percent_Identity=24.7334754797441, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281366494, Length=440, Percent_Identity=24.7727272727273, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24667139, Length=440, Percent_Identity=24.7727272727273, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24667143, Length=440, Percent_Identity=24.7727272727273, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 48934; Mature: 48803

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVQTSSKNQVFLEQQNRRESNARSYPRRFPLAMQTAEGVLVTDADGKQYYDCLAGAGTL
CCCCCCCCCEEEEEHHHCCHHHHHCCCHHCCCCEECCCCEEEECCCCHHHHHHHHCCCEE
ALGHNHPVVIEAIQKMIEEKRPLHTLDITSEIKEEFVNEVFASLPEAFAKRAKIQFCGPT
EECCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCC
GGDAIEAALKLVKTATGKRTILSFHGAYHGATHGTMALSGNLSPKENVQGLMPDVHFLPY
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCC
PYEYRCPFGKGGEASHKLSSAYIENMLDDPESGVLQPAGMIFEAVQGEGGSVPARAEWIR
CCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
EMRRITKERGIPLIIDEVQTGIGRTGKMFAFEHAGIIPDVIVLSKAIGGSLPLSVVIYDQ
HHHHHHHHCCCCEEEHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEC
DLDQWGPGAHIGTFRGNQMAMAAGSATLKYIKEHDVLSHVEKVGAKLMRELQDIQEHVPE
CCCCCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
IGDVRGRGLMIGAEIVAPHKKQNANGSYPADAELASTIQRKCFEKGLIVETGGRHGSVIR
HHCCCCCEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHH
FLPPLIVTEAQIDDIITIFREAVYEAVK
HHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVQTSSKNQVFLEQQNRRESNARSYPRRFPLAMQTAEGVLVTDADGKQYYDCLAGAGTL
CCCCCCCCEEEEEHHHCCHHHHHCCCHHCCCCEECCCCEEEECCCCHHHHHHHHCCCEE
ALGHNHPVVIEAIQKMIEEKRPLHTLDITSEIKEEFVNEVFASLPEAFAKRAKIQFCGPT
EECCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCC
GGDAIEAALKLVKTATGKRTILSFHGAYHGATHGTMALSGNLSPKENVQGLMPDVHFLPY
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCC
PYEYRCPFGKGGEASHKLSSAYIENMLDDPESGVLQPAGMIFEAVQGEGGSVPARAEWIR
CCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
EMRRITKERGIPLIIDEVQTGIGRTGKMFAFEHAGIIPDVIVLSKAIGGSLPLSVVIYDQ
HHHHHHHHCCCCEEEHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEC
DLDQWGPGAHIGTFRGNQMAMAAGSATLKYIKEHDVLSHVEKVGAKLMRELQDIQEHVPE
CCCCCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
IGDVRGRGLMIGAEIVAPHKKQNANGSYPADAELASTIQRKCFEKGLIVETGGRHGSVIR
HHCCCCCEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHH
FLPPLIVTEAQIDDIITIFREAVYEAVK
HHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]