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The map label for this gene is ddc [H]

Identifier: 52784956

GI number: 52784956

Start: 1192699

End: 1194210

Strand: Direct

Name: ddc [H]

Synonym: BLi01184

Alternate gene names: 52784956

Gene position: 1192699-1194210 (Clockwise)

Preceding gene: 52784955

Following gene: 52784957

Centisome position: 28.25

GC content: 50.99

Gene sequence:

>1512_bases
ATGAAGCAGTCAAGTAAACAAAAAAACTTTGATTCCCTGTTTATGCACAACGGGGAACAGGGGATCAAAGCATACCGTGA
CGCGGTAGAGACCGCTGTAGAGACGCTTTGGGCCGATTGGAAGAATAAATCGAAGCCCTACAGCGGGAAGATGCCGAAAG
AATTGGATCTCGAAATCAAAAGCTTGTTTTCGTTTCAGGAAGCGGGAGAATCGCTTGCGGATGTTCTTGAGCATCTGAAA
GAAGCCTATTTGCCGCACCGGATTCATGTTGAAGATCCAAAATGCGCCGCACACCTGCACTGTCCGCCGCTGATCCCGGC
GCTTGCTGCAGAGATGCTGATCAGCGTGCTGAATCAGTCGATGGATTCGTTTGATCAAAGCGGAGCGGCTTCATTGATCG
AGGAAGAAATGGTGCAGTGGCTTTGCCGAAAGTTTGAATACGGAAAAGATGCTGACGGAACATTTACGAGCGGAGGGACA
CAGTCTAATTACATGGGGCTTCTTTTGGCCCGCGATGCCTTCTGCGAAAAGCAGTGGAACTGGAATGTACAGAAGGACGG
ACTGCCGCCGGAAGCGAACAGGCTGCGGATCCTCTGTTCAAAGGATGCTCATTTTACCGTGAAAAAGTCGGCTTCCCAGC
TCGGCCTCGGAGAGCGCGCCGTCGTGCTTGTCGATACCGATGCTGAAAAGCGGATGAGCCTTTACGATTTAAAGCAAAAA
ACCGCTATGCTGAAGGAATCGGGCTTACATCCATTTGCGATTGTCGCAACATGCGGAACGACGGACTTCGGAAGCATCGA
TCCGCTTTCCGAGCTTGCGGATGCCGCGCATGCTGGCGGGCTTTGGTTCCACGTTGATGCCGCATATGGCGGAGCGTTGA
TTTTGAGCAGGACCCGCCGCTATAAATTGGCTGGGATCGACAGGGCCGATTCAATCAGCGTCGACTTCCACAAGCAGTTT
TATCAGCCGGTCAGCTGCGGCGCTTTTCTTGTAAAAGACAGAAGACATTTCCGCTTGATTGATTATCATGCCGATTATTT
AAATCCTGAGGAGGATGAAGCGGAGGGAATCGTTCATCTCGTCAATAAATCGATTCAGACGACGCGGCGCTTTGACGCCT
TAAAGCTGTTTGTCTCGCTGCGTGTGCTTGGAGAAGATACATTCGCCGAGATGATCGACTGGACATTCGCATTGGCTGAA
GCGGCAGCGGAAAAAATCTCAGCAAGCGATCGGTTCGAACTGCTGAATCCGCACCCTGAACTGAACGCTGTCGTCTTCCG
CTGCCTCGCCTCAGAAGACGACGCGGAGAACGACCGTTTGAATAAATGTATCCACAGAGAATTGTTCAGAACGGGACAGG
CGGTGATCGCAAAGACGGCAGCAGCTGGGAAAACATATTTAAAATTCACGCTGCTGAATCCGCGGACGACGCTTTCGGAT
CTTGATGACATTCTCGGGAGGATTCAAGAGCTTGCAAGTCTTTATACGAATAGCAGGAGGGTAACAGGATGA

Upstream 100 bases:

>100_bases
ACGGGAGGCCGCCACGGAAGCGTGATCCGCTTCTTGCCGCCGCTTATCGTAACAGAGGCGCAAATCGACGATATCATCAC
GATCTTCAGAGAGGCCGTCT

Downstream 100 bases:

>100_bases
GTTCATTTAAAGAAATAGCAGAAAACGCCACGATTCAAAGCTTTTTAAATTGCTATTTGCGTGAAACCGGCATCGAAACC
CGTGAGATCGCGGACGGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKQSSKQKNFDSLFMHNGEQGIKAYRDAVETAVETLWADWKNKSKPYSGKMPKELDLEIKSLFSFQEAGESLADVLEHLK
EAYLPHRIHVEDPKCAAHLHCPPLIPALAAEMLISVLNQSMDSFDQSGAASLIEEEMVQWLCRKFEYGKDADGTFTSGGT
QSNYMGLLLARDAFCEKQWNWNVQKDGLPPEANRLRILCSKDAHFTVKKSASQLGLGERAVVLVDTDAEKRMSLYDLKQK
TAMLKESGLHPFAIVATCGTTDFGSIDPLSELADAAHAGGLWFHVDAAYGGALILSRTRRYKLAGIDRADSISVDFHKQF
YQPVSCGAFLVKDRRHFRLIDYHADYLNPEEDEAEGIVHLVNKSIQTTRRFDALKLFVSLRVLGEDTFAEMIDWTFALAE
AAAEKISASDRFELLNPHPELNAVVFRCLASEDDAENDRLNKCIHRELFRTGQAVIAKTAAAGKTYLKFTLLNPRTTLSD
LDDILGRIQELASLYTNSRRVTG

Sequences:

>Translated_503_residues
MKQSSKQKNFDSLFMHNGEQGIKAYRDAVETAVETLWADWKNKSKPYSGKMPKELDLEIKSLFSFQEAGESLADVLEHLK
EAYLPHRIHVEDPKCAAHLHCPPLIPALAAEMLISVLNQSMDSFDQSGAASLIEEEMVQWLCRKFEYGKDADGTFTSGGT
QSNYMGLLLARDAFCEKQWNWNVQKDGLPPEANRLRILCSKDAHFTVKKSASQLGLGERAVVLVDTDAEKRMSLYDLKQK
TAMLKESGLHPFAIVATCGTTDFGSIDPLSELADAAHAGGLWFHVDAAYGGALILSRTRRYKLAGIDRADSISVDFHKQF
YQPVSCGAFLVKDRRHFRLIDYHADYLNPEEDEAEGIVHLVNKSIQTTRRFDALKLFVSLRVLGEDTFAEMIDWTFALAE
AAAEKISASDRFELLNPHPELNAVVFRCLASEDDAENDRLNKCIHRELFRTGQAVIAKTAAAGKTYLKFTLLNPRTTLSD
LDDILGRIQELASLYTNSRRVTG
>Mature_503_residues
MKQSSKQKNFDSLFMHNGEQGIKAYRDAVETAVETLWADWKNKSKPYSGKMPKELDLEIKSLFSFQEAGESLADVLEHLK
EAYLPHRIHVEDPKCAAHLHCPPLIPALAAEMLISVLNQSMDSFDQSGAASLIEEEMVQWLCRKFEYGKDADGTFTSGGT
QSNYMGLLLARDAFCEKQWNWNVQKDGLPPEANRLRILCSKDAHFTVKKSASQLGLGERAVVLVDTDAEKRMSLYDLKQK
TAMLKESGLHPFAIVATCGTTDFGSIDPLSELADAAHAGGLWFHVDAAYGGALILSRTRRYKLAGIDRADSISVDFHKQF
YQPVSCGAFLVKDRRHFRLIDYHADYLNPEEDEAEGIVHLVNKSIQTTRRFDALKLFVSLRVLGEDTFAEMIDWTFALAE
AAAEKISASDRFELLNPHPELNAVVFRCLASEDDAENDRLNKCIHRELFRTGQAVIAKTAAAGKTYLKFTLLNPRTTLSD
LDDILGRIQELASLYTNSRRVTG

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197383062, Length=450, Percent_Identity=28.4444444444444, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI194294551, Length=477, Percent_Identity=29.3501048218029, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI197276620, Length=497, Percent_Identity=27.1629778672032, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI4503875, Length=497, Percent_Identity=27.1629778672032, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI58331246, Length=442, Percent_Identity=28.0542986425339, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI4503281, Length=442, Percent_Identity=23.5294117647059, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI132814448, Length=442, Percent_Identity=23.5294117647059, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI92110055, Length=448, Percent_Identity=24.1071428571429, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17555682, Length=441, Percent_Identity=25.8503401360544, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71993062, Length=411, Percent_Identity=26.2773722627737, Blast_Score=151, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI71993058, Length=355, Percent_Identity=28.169014084507, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17534817, Length=425, Percent_Identity=25.1764705882353, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17534819, Length=425, Percent_Identity=25.1764705882353, Blast_Score=115, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71981211, Length=311, Percent_Identity=27.9742765273312, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71981217, Length=311, Percent_Identity=27.9742765273312, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI133931025, Length=434, Percent_Identity=23.963133640553, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551992, Length=296, Percent_Identity=24.6621621621622, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356415, Length=323, Percent_Identity=32.8173374613003, Blast_Score=161, Evalue=9e-40,
Organism=Drosophila melanogaster, GI17136594, Length=453, Percent_Identity=28.0353200883002, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24657193, Length=323, Percent_Identity=27.5541795665635, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24657185, Length=323, Percent_Identity=27.5541795665635, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24657188, Length=323, Percent_Identity=27.5541795665635, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24652373, Length=450, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28573972, Length=439, Percent_Identity=25.7403189066059, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221476190, Length=386, Percent_Identity=26.6839378238342, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585143, Length=386, Percent_Identity=26.6839378238342, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585139, Length=386, Percent_Identity=26.6839378238342, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17136190, Length=437, Percent_Identity=25.1716247139588, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24586044, Length=427, Percent_Identity=23.6533957845433, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24585135, Length=462, Percent_Identity=24.4588744588745, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 56333; Mature: 56333

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSSKQKNFDSLFMHNGEQGIKAYRDAVETAVETLWADWKNKSKPYSGKMPKELDLEIK
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
SLFSFQEAGESLADVLEHLKEAYLPHRIHVEDPKCAAHLHCPPLIPALAAEMLISVLNQS
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHH
MDSFDQSGAASLIEEEMVQWLCRKFEYGKDADGTFTSGGTQSNYMGLLLARDAFCEKQWN
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCC
WNVQKDGLPPEANRLRILCSKDAHFTVKKSASQLGLGERAVVLVDTDAEKRMSLYDLKQK
CCCCCCCCCCCCCCEEEEECCCCCEEEECCHHHCCCCCEEEEEEECCHHHHHHHHHHHHH
TAMLKESGLHPFAIVATCGTTDFGSIDPLSELADAAHAGGLWFHVDAAYGGALILSRTRR
HHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEHHCCC
YKLAGIDRADSISVDFHKQFYQPVSCGAFLVKDRRHFRLIDYHADYLNPEEDEAEGIVHL
EEEECCCCCCCCCHHHHHHHCCCCCCCHHEECCCCCEEEEEEECCCCCCCCHHHHHHHHH
VNKSIQTTRRFDALKLFVSLRVLGEDTFAEMIDWTFALAEAAAEKISASDRFELLNPHPE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCC
LNAVVFRCLASEDDAENDRLNKCIHRELFRTGQAVIAKTAAAGKTYLKFTLLNPRTTLSD
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCHHH
LDDILGRIQELASLYTNSRRVTG
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQSSKQKNFDSLFMHNGEQGIKAYRDAVETAVETLWADWKNKSKPYSGKMPKELDLEIK
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
SLFSFQEAGESLADVLEHLKEAYLPHRIHVEDPKCAAHLHCPPLIPALAAEMLISVLNQS
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHH
MDSFDQSGAASLIEEEMVQWLCRKFEYGKDADGTFTSGGTQSNYMGLLLARDAFCEKQWN
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCC
WNVQKDGLPPEANRLRILCSKDAHFTVKKSASQLGLGERAVVLVDTDAEKRMSLYDLKQK
CCCCCCCCCCCCCCEEEEECCCCCEEEECCHHHCCCCCEEEEEEECCHHHHHHHHHHHHH
TAMLKESGLHPFAIVATCGTTDFGSIDPLSELADAAHAGGLWFHVDAAYGGALILSRTRR
HHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEHHCCC
YKLAGIDRADSISVDFHKQFYQPVSCGAFLVKDRRHFRLIDYHADYLNPEEDEAEGIVHL
EEEECCCCCCCCCHHHHHHHCCCCCCCHHEECCCCCEEEEEEECCCCCCCCHHHHHHHHH
VNKSIQTTRRFDALKLFVSLRVLGEDTFAEMIDWTFALAEAAAEKISASDRFELLNPHPE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCC
LNAVVFRCLASEDDAENDRLNKCIHRELFRTGQAVIAKTAAAGKTYLKFTLLNPRTTLSD
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCHHH
LDDILGRIQELASLYTNSRRVTG
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]