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The map label for this gene is sdcS [H]

Identifier: 52784308

GI number: 52784308

Start: 495054

End: 496694

Strand: Direct

Name: sdcS [H]

Synonym: BLi00488

Alternate gene names: 52784308

Gene position: 495054-496694 (Clockwise)

Preceding gene: 52784306

Following gene: 52784309

Centisome position: 11.72

GC content: 49.3

Gene sequence:

>1641_bases
ATGAAATCAAGCGTTGTGTCAGCATGGGATATGCTTTGGAGATCACACCGGGAAGCAAAGAGGCTGCTTTTGTTCGCCAT
GCCTGTCAGGGCGGGAAAAGATGCCGGTTTAAAGATAAATTCGGAACAAACCATGAAGGAAGAGAAGCCGCCGAGCTATA
AAACGCCTCAAAAAATCGGGCTGCTGCTTGGTCCTGCATTGTTTTTCGCTGTCCTTTTGTTCTTTTTTCCCGAGGGTCTG
AGCTATGAAGGTAGAATGGTATTGGCGACTACTTTGTGGGTTGCGGTTTGGTGGATTACGGAGGCTGTTCCGATTCCGGC
TGCATCATTGCTGCCGATCGTGCTGCTTCCGCTGACGGGGGCGCTGGAAGGGGCAGCTGTCACGTCGAGCTACGGCGATC
CGATCGTCTTTTTATTCTTAGGGGGCTTCTTGATTGCACTTGCGATGGAACGTTGGAATCTCCATAAACGGATTGCGCTC
AATATTATTTCTGTAGTGGGCACGAGCACCTCGAGGATCGTCCTCGGTTTTATGGCGGCCACAGGATTTTTGTCTATGTG
GGTCTCAAATACGGCCGCGGTGATGATGATGCTTCCAATTGGAACCGCTATCATTCATCAGGTATCAGCTGTCATAAAGT
CTGAAAGAAAAGATTTAGCCGCAGAAGAGGCGAAATTTTCAAAAGCGCTGATCTTCAGCATCGGGTATGCGGGGACAATC
GGCGGACTCGGTACGCTGATCGGCACGCCGCCGAACATTATTTTGGCGGCCAATATTAAGAAGCTGTACGGAGTTGAAGT
GTCTTTCGGCGGATGGATGGCTTTTGCCGTTCCGGTCGTCGTCATTTTGCTTGTAGCGGTATGGCTGTACTTGACGAAAG
TGGCGCATCCGATCAAGATGAAGGAGCTTCCGGGCGGAAAAGAATTGATTCTCGAAGAAAAAAGAAAGCTTGGAAAGATG
AGTTTTGAAGAAACAATGGTTCTGCTCGTCTTCGGGTTTGCCGCGTTTATGTGGGTGACGAGAACGTTTTTATGGGATGA
CAAAATACCGGGTATTGACGATACAATGATTGCGATATTCGCCGCTTCATTGCTCTTCTTGATCCCTTCGCTCAATAAAG
GGGGCAGGGTATTGGACTGGTCGGTATCAAAGGACTTGCCGTGGGGGATTCTCCTTTTATTCGGAGGAGGCTTGGCGCTC
GCAACAGGTTTTAAAGAAACGGGTCTGGCGGAGTGGATCGGCGGAAGGCTGACGGTATTGGATGGATTTAACTTTGTGGT
TATTGTCATCATCTCAACGGCATTGGTGCTGTTTTTGACGGAGATTACGTCGAATACGGCTACGGCGACCATGATTCTGC
CTGTACTGGCCTCGCTCGCTTTAGCGCTGAATGTTCATCCGTACGCATTAATGGTGCCTGCTGCAATGGCGGCAAACTGC
GCCTTCATGCTGCCGGTCGGCACGCCGCCGAATGCAATTATTTTCGCATCGGGCAAATTGAAGATCAGCGAAATGGTTCG
AACCGGCTTTGTCATTAATATTTTCACGCTAATTTTAATCGTCGGAGCTGTGTTCTACATTCTTCCGCATTTATGGGGAG
TAGATCTGACCGTCTTCCCCGACAATCTGAAATCGAATTGA

Upstream 100 bases:

>100_bases
CTGTCCGTTATAATTAAGTTATAACTGTCGACAGTCGGCAGATTACTTTTTGATTATTATTGTAAGCGCTTTATAGATAG
AGGGGAAGGGGGAGTTTTTT

Downstream 100 bases:

>100_bases
TGAAGCGAAGCCGGAGCTTAAGCCCCGGCTTTTGGTCATGGTGAAGCTTGCAATTGATCGTTCAGCAGCCATTTAAAAAG
AGAAAAAAATGAAACTGCTG

Product: hypothetical protein

Products: tartrate [Cytoplasm]; succinate [Periplasm] [C]

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKSSVVSAWDMLWRSHREAKRLLLFAMPVRAGKDAGLKINSEQTMKEEKPPSYKTPQKIGLLLGPALFFAVLLFFFPEGL
SYEGRMVLATTLWVAVWWITEAVPIPAASLLPIVLLPLTGALEGAAVTSSYGDPIVFLFLGGFLIALAMERWNLHKRIAL
NIISVVGTSTSRIVLGFMAATGFLSMWVSNTAAVMMMLPIGTAIIHQVSAVIKSERKDLAAEEAKFSKALIFSIGYAGTI
GGLGTLIGTPPNIILAANIKKLYGVEVSFGGWMAFAVPVVVILLVAVWLYLTKVAHPIKMKELPGGKELILEEKRKLGKM
SFEETMVLLVFGFAAFMWVTRTFLWDDKIPGIDDTMIAIFAASLLFLIPSLNKGGRVLDWSVSKDLPWGILLLFGGGLAL
ATGFKETGLAEWIGGRLTVLDGFNFVVIVIISTALVLFLTEITSNTATATMILPVLASLALALNVHPYALMVPAAMAANC
AFMLPVGTPPNAIIFASGKLKISEMVRTGFVINIFTLILIVGAVFYILPHLWGVDLTVFPDNLKSN

Sequences:

>Translated_546_residues
MKSSVVSAWDMLWRSHREAKRLLLFAMPVRAGKDAGLKINSEQTMKEEKPPSYKTPQKIGLLLGPALFFAVLLFFFPEGL
SYEGRMVLATTLWVAVWWITEAVPIPAASLLPIVLLPLTGALEGAAVTSSYGDPIVFLFLGGFLIALAMERWNLHKRIAL
NIISVVGTSTSRIVLGFMAATGFLSMWVSNTAAVMMMLPIGTAIIHQVSAVIKSERKDLAAEEAKFSKALIFSIGYAGTI
GGLGTLIGTPPNIILAANIKKLYGVEVSFGGWMAFAVPVVVILLVAVWLYLTKVAHPIKMKELPGGKELILEEKRKLGKM
SFEETMVLLVFGFAAFMWVTRTFLWDDKIPGIDDTMIAIFAASLLFLIPSLNKGGRVLDWSVSKDLPWGILLLFGGGLAL
ATGFKETGLAEWIGGRLTVLDGFNFVVIVIISTALVLFLTEITSNTATATMILPVLASLALALNVHPYALMVPAAMAANC
AFMLPVGTPPNAIIFASGKLKISEMVRTGFVINIFTLILIVGAVFYILPHLWGVDLTVFPDNLKSN
>Mature_546_residues
MKSSVVSAWDMLWRSHREAKRLLLFAMPVRAGKDAGLKINSEQTMKEEKPPSYKTPQKIGLLLGPALFFAVLLFFFPEGL
SYEGRMVLATTLWVAVWWITEAVPIPAASLLPIVLLPLTGALEGAAVTSSYGDPIVFLFLGGFLIALAMERWNLHKRIAL
NIISVVGTSTSRIVLGFMAATGFLSMWVSNTAAVMMMLPIGTAIIHQVSAVIKSERKDLAAEEAKFSKALIFSIGYAGTI
GGLGTLIGTPPNIILAANIKKLYGVEVSFGGWMAFAVPVVVILLVAVWLYLTKVAHPIKMKELPGGKELILEEKRKLGKM
SFEETMVLLVFGFAAFMWVTRTFLWDDKIPGIDDTMIAIFAASLLFLIPSLNKGGRVLDWSVSKDLPWGILLLFGGGLAL
ATGFKETGLAEWIGGRLTVLDGFNFVVIVIISTALVLFLTEITSNTATATMILPVLASLALALNVHPYALMVPAAMAANC
AFMLPVGTPPNAIIFASGKLKISEMVRTGFVINIFTLILIVGAVFYILPHLWGVDLTVFPDNLKSN

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=520, Percent_Identity=36.7307692307692, Blast_Score=298, Evalue=1e-80,
Organism=Homo sapiens, GI31377715, Length=552, Percent_Identity=35.8695652173913, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI58761541, Length=541, Percent_Identity=35.6746765249538, Blast_Score=288, Evalue=1e-77,
Organism=Homo sapiens, GI4506979, Length=536, Percent_Identity=34.8880597014925, Blast_Score=279, Evalue=6e-75,
Organism=Homo sapiens, GI301069349, Length=531, Percent_Identity=34.2749529190207, Blast_Score=271, Evalue=1e-72,
Organism=Homo sapiens, GI225637549, Length=585, Percent_Identity=32.991452991453, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI301069346, Length=522, Percent_Identity=35.4406130268199, Blast_Score=253, Evalue=4e-67,
Organism=Homo sapiens, GI225637552, Length=492, Percent_Identity=35.3658536585366, Blast_Score=253, Evalue=4e-67,
Organism=Homo sapiens, GI301069353, Length=490, Percent_Identity=34.6938775510204, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI19923838, Length=544, Percent_Identity=32.3529411764706, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI219802232, Length=435, Percent_Identity=35.8620689655172, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI31795546, Length=362, Percent_Identity=32.8729281767956, Blast_Score=184, Evalue=2e-46,
Organism=Escherichia coli, GI1789444, Length=418, Percent_Identity=24.8803827751196, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786986, Length=419, Percent_Identity=25.7756563245823, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786829, Length=419, Percent_Identity=23.3890214797136, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71989118, Length=521, Percent_Identity=31.8618042226488, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI71988385, Length=485, Percent_Identity=32.9896907216495, Blast_Score=257, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI32565804, Length=458, Percent_Identity=33.1877729257642, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI32564681, Length=552, Percent_Identity=29.1666666666667, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17551790, Length=531, Percent_Identity=28.4369114877589, Blast_Score=216, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6324340, Length=458, Percent_Identity=25.3275109170306, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322263, Length=426, Percent_Identity=23.7089201877934, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319885, Length=428, Percent_Identity=24.2990654205607, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281362116, Length=555, Percent_Identity=33.6936936936937, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI281362114, Length=555, Percent_Identity=33.5135135135135, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI281362112, Length=555, Percent_Identity=33.5135135135135, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI45551633, Length=531, Percent_Identity=30.8851224105461, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI281366409, Length=505, Percent_Identity=31.4851485148515, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI17737623, Length=505, Percent_Identity=31.4851485148515, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24666468, Length=505, Percent_Identity=31.4851485148515, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI78706796, Length=516, Percent_Identity=30.2325581395349, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI78706798, Length=516, Percent_Identity=30.2325581395349, Blast_Score=170, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 59162; Mature: 59162

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSVVSAWDMLWRSHREAKRLLLFAMPVRAGKDAGLKINSEQTMKEEKPPSYKTPQKIG
CCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEECCHHHHHHCCCCCCCCHHHHH
LLLGPALFFAVLLFFFPEGLSYEGRMVLATTLWVAVWWITEAVPIPAASLLPIVLLPLTG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
ALEGAAVTSSYGDPIVFLFLGGFLIALAMERWNLHKRIALNIISVVGTSTSRIVLGFMAA
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHH
TGFLSMWVSNTAAVMMMLPIGTAIIHQVSAVIKSERKDLAAEEAKFSKALIFSIGYAGTI
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
GGLGTLIGTPPNIILAANIKKLYGVEVSFGGWMAFAVPVVVILLVAVWLYLTKVAHPIKM
CCHHHHCCCCCCEEEEECCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KELPGGKELILEEKRKLGKMSFEETMVLLVFGFAAFMWVTRTFLWDDKIPGIDDTMIAIF
HCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AASLLFLIPSLNKGGRVLDWSVSKDLPWGILLLFGGGLALATGFKETGLAEWIGGRLTVL
HHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHCCEEEEE
DGFNFVVIVIISTALVLFLTEITSNTATATMILPVLASLALALNVHPYALMVPAAMAANC
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
AFMLPVGTPPNAIIFASGKLKISEMVRTGFVINIFTLILIVGAVFYILPHLWGVDLTVFP
EEEEECCCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
DNLKSN
CCCCCC
>Mature Secondary Structure
MKSSVVSAWDMLWRSHREAKRLLLFAMPVRAGKDAGLKINSEQTMKEEKPPSYKTPQKIG
CCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEECCHHHHHHCCCCCCCCHHHHH
LLLGPALFFAVLLFFFPEGLSYEGRMVLATTLWVAVWWITEAVPIPAASLLPIVLLPLTG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
ALEGAAVTSSYGDPIVFLFLGGFLIALAMERWNLHKRIALNIISVVGTSTSRIVLGFMAA
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHH
TGFLSMWVSNTAAVMMMLPIGTAIIHQVSAVIKSERKDLAAEEAKFSKALIFSIGYAGTI
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
GGLGTLIGTPPNIILAANIKKLYGVEVSFGGWMAFAVPVVVILLVAVWLYLTKVAHPIKM
CCHHHHCCCCCCEEEEECCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KELPGGKELILEEKRKLGKMSFEETMVLLVFGFAAFMWVTRTFLWDDKIPGIDDTMIAIF
HCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AASLLFLIPSLNKGGRVLDWSVSKDLPWGILLLFGGGLALATGFKETGLAEWIGGRLTVL
HHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHCCEEEEE
DGFNFVVIVIISTALVLFLTEITSNTATATMILPVLASLALALNVHPYALMVPAAMAANC
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
AFMLPVGTPPNAIIFASGKLKISEMVRTGFVINIFTLILIVGAVFYILPHLWGVDLTVFP
EEEEECCCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
DNLKSN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: tartrate [Periplasm]; succinate [Cytoplasm] [C]

Specific reaction: tartrate [Periplasm] + succinate [Cytoplasm] = tartrate [Cytoplasm] + succinate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA