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The map label for this gene is vgb [H]

Identifier: 52784087

GI number: 52784087

Start: 236083

End: 237024

Strand: Direct

Name: vgb [H]

Synonym: BLi00263

Alternate gene names: 52784087

Gene position: 236083-237024 (Clockwise)

Preceding gene: 52784084

Following gene: 52784091

Centisome position: 5.59

GC content: 53.61

Gene sequence:

>942_bases
ATGAGAGATGCCTGGGGCAAAATAGCTTGCAGGAAAAAGGAAGGGAGGGTATCCATGCAGATTCGCATGACTGAATATCA
GGTTCCCGACCCCGAATCGGGGCCGTACGGGATCACAGTATGTGCAAACGGGCGCATTTGGTTTACTGAACAAAAGGGGA
ACCGGATTGGTATGCTCACAGAGTCCGGGGATATCACCGAATATACGATTCCGACGGAGAGCGCAGGCGCCTCGATTATT
ACGTCCGGGATTGACGGCGAGCTTTGGTTTACAGAGTATAAAGCGGGGAAAATCGGCAAAATCACGCCTCAAGGGAAAAT
AACCGAGTATGCTCTTCCACCGGGTGCTGCCCCGTTTGGAATCGCTGCAGGCTGTGACGACGCCATGTGGTATACAGATA
TGGCCGGACATCAAATCGGCAGGCTGTCCTCTTCAGGCGAAATAACAGAATACAAACTGCCCAAACCAGGAGCCTTCCCG
TCATTTATTACAAGGGGAGCAGACGGCGCGCTCTGGTTTACACAAAACCAAAGCGGCTCCATCGGGCGAATAACGGCAGA
TGGAGACATCAGCGAGTATCCGCTGCCCCAAGAACAATCCGGCCCGGTCGGGATCACTGCCGGCCCGGACGGGGCTTTAT
GGTTTACAGAAATAAACGCAAATCAAATTGGGAGAATAACGGTCTCAGGAAAGATCAGCGAATACCAGCTTCCGACAGCG
CATGCACGCCCGCACGCGATTGCCGCAGGCGGTGACGGAGCACTGTGGTTTACGGAATGGGGCGCGGGTCAAATCGGCCG
CATTACAGTCGACGGGGATATTACGGAATATCCAATCCCGACGGCAGATTCTGAACCGCACGGGATAGCGGCCGGATCAG
CCCATTCGATCTGGTTTGCAGAAGAGTGCGGCCGTATTGGGAAAATCTCTATCCAAAATTAA

Upstream 100 bases:

>100_bases
ATATTTTAAAACCATTTTATGATACTAGAGTGAGCCTGTACAATTCATATTGATGGAATTTTTTGTTTCACTGCATGCTC
CCCCCTGAGGTAACATAAAA

Downstream 100 bases:

>100_bases
GAAACGTCCAGCCAACTGGACGTTCTTTTTTTATTGTTATTCCGTTCTCGTTTCCATTCTGCGGTTGGGCGAGCCAAGGC
CTTTATTCATCAAGTAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Streptogramin B lyase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRDAWGKIACRKKEGRVSMQIRMTEYQVPDPESGPYGITVCANGRIWFTEQKGNRIGMLTESGDITEYTIPTESAGASII
TSGIDGELWFTEYKAGKIGKITPQGKITEYALPPGAAPFGIAAGCDDAMWYTDMAGHQIGRLSSSGEITEYKLPKPGAFP
SFITRGADGALWFTQNQSGSIGRITADGDISEYPLPQEQSGPVGITAGPDGALWFTEINANQIGRITVSGKISEYQLPTA
HARPHAIAAGGDGALWFTEWGAGQIGRITVDGDITEYPIPTADSEPHGIAAGSAHSIWFAEECGRIGKISIQN

Sequences:

>Translated_313_residues
MRDAWGKIACRKKEGRVSMQIRMTEYQVPDPESGPYGITVCANGRIWFTEQKGNRIGMLTESGDITEYTIPTESAGASII
TSGIDGELWFTEYKAGKIGKITPQGKITEYALPPGAAPFGIAAGCDDAMWYTDMAGHQIGRLSSSGEITEYKLPKPGAFP
SFITRGADGALWFTQNQSGSIGRITADGDISEYPLPQEQSGPVGITAGPDGALWFTEINANQIGRITVSGKISEYQLPTA
HARPHAIAAGGDGALWFTEWGAGQIGRITVDGDITEYPIPTADSEPHGIAAGSAHSIWFAEECGRIGKISIQN
>Mature_313_residues
MRDAWGKIACRKKEGRVSMQIRMTEYQVPDPESGPYGITVCANGRIWFTEQKGNRIGMLTESGDITEYTIPTESAGASII
TSGIDGELWFTEYKAGKIGKITPQGKITEYALPPGAAPFGIAAGCDDAMWYTDMAGHQIGRLSSSGEITEYKLPKPGAFP
SFITRGADGALWFTQNQSGSIGRITADGDISEYPLPQEQSGPVGITAGPDGALWFTEINANQIGRITVSGKISEYQLPTA
HARPHAIAAGGDGALWFTEWGAGQIGRITVDGDITEYPIPTADSEPHGIAAGSAHSIWFAEECGRIGKISIQN

Specific function: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid [H]

COG id: COG4257

COG function: function code V; Streptogramin lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the vgb family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011217 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33418; Mature: 33418

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDAWGKIACRKKEGRVSMQIRMTEYQVPDPESGPYGITVCANGRIWFTEQKGNRIGMLT
CCCCCCCEEEEECCCCEEEEEEEEEEECCCCCCCCEEEEEEECCEEEEEECCCCEEEEEE
ESGDITEYTIPTESAGASIITSGIDGELWFTEYKAGKIGKITPQGKITEYALPPGAAPFG
CCCCEEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCEEECCCCCEEEEECCCCCCCCC
IAAGCDDAMWYTDMAGHQIGRLSSSGEITEYKLPKPGAFPSFITRGADGALWFTQNQSGS
EECCCCCCEEEECCCCCHHCCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEEEEECCCCC
IGRITADGDISEYPLPQEQSGPVGITAGPDGALWFTEINANQIGRITVSGKISEYQLPTA
EEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCEEEEEEECCCEEEECCCC
HARPHAIAAGGDGALWFTEWGAGQIGRITVDGDITEYPIPTADSEPHGIAAGSAHSIWFA
CCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCEECCCCCCCCCCCCEECCCCCEEEEH
EECGRIGKISIQN
HHCCCCCEEEECC
>Mature Secondary Structure
MRDAWGKIACRKKEGRVSMQIRMTEYQVPDPESGPYGITVCANGRIWFTEQKGNRIGMLT
CCCCCCCEEEEECCCCEEEEEEEEEEECCCCCCCCEEEEEEECCEEEEEECCCCEEEEEE
ESGDITEYTIPTESAGASIITSGIDGELWFTEYKAGKIGKITPQGKITEYALPPGAAPFG
CCCCEEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCEEECCCCCEEEEECCCCCCCCC
IAAGCDDAMWYTDMAGHQIGRLSSSGEITEYKLPKPGAFPSFITRGADGALWFTQNQSGS
EECCCCCCEEEECCCCCHHCCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEEEEECCCCC
IGRITADGDISEYPLPQEQSGPVGITAGPDGALWFTEINANQIGRITVSGKISEYQLPTA
EEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCEEEEEEECCCEEEECCCC
HARPHAIAAGGDGALWFTEWGAGQIGRITVDGDITEYPIPTADSEPHGIAAGSAHSIWFA
CCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCEECCCCCCCCCCCCEECCCCCEEEEH
EECGRIGKISIQN
HHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA