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The map label for this gene is adp [C]

Identifier: 52142382

GI number: 52142382

Start: 2981593

End: 2982750

Strand: Reverse

Name: adp [C]

Synonym: BCZK2860

Alternate gene names: 52142382

Gene position: 2982750-2981593 (Counterclockwise)

Preceding gene: 52142380

Following gene: 52142385

Centisome position: 56.27

GC content: 39.64

Gene sequence:

>1158_bases
ATGAAAATACGTAGTAAAATTACATGTGCAAGTCTAGCGCTTTTAATAGCTGGAAGTTCCCTGTTATACATAACACCAGC
CTCAATTGTAAAAGCAGAACCTACGCAAAATGTATCTAGTTCGTTACAAACAAGTACGCAAAGTAATCGTACTTCCGTTA
AGAAAGCAATACGTGATGAACTGCAACTTGGATACCCGGGAATACTCGCTCAAATTTCTAAGGGTGGTAAAACTTGGAGT
TATACCGCTGGGGTAGCGGATCTGAGAACTAAGAAACCAATGAAAGCAGATTTTCGCTTTCGCATTGGCAGTGTGACGAA
AACGTTCATTGCAACAGTGCTACTTCAATTATCTGGAGAGAACCGTTTGAATCTAGATGACTCCATTGAAAAATGGTTGC
CTGGTGTCATTCAAGGAAACGGATATGATGGTAACCAGATTACGATCCGGCAAATATTGAATCATACAAGTGGTATTGCT
GACTATATAAATTCAAAAGATTTTGATATTACGGATATAAAAAAATCGTATACAGCTGAAGAATTTGTAAAGATGGGGAT
TTCTCTTCCCCCAGACTTTGCTCCAGGAAAGGCGTGGTCTTATTCAAACACAGGATACGTATTACTGGGGATCCTTATTG
AAAAAGTAACTGGAAACAGCTATGCGGAAGAGGTTGAAAATCGCATTATTGAACCGCTTGATTTGTCAAATACATTCCTA
CCTGGCAATTCAAGCGTGATTCCAGGCACAAAGCATGCCCGTGGCTATTTGCAACTAGACGGAGCAAGTGAGCTAAAAGA
CGTTACTTATATTAACCCAGGTAGCTCGGATGGAGATATGATTTCTACTGCTGACGACTTAAACAAATTCTTCTCTTACT
TACTAGGTGGCAAATTACTGAAGGAACAGCAACTAAAACAAATGCTTACTACAGTTCCTACAGAAAGAGAGGGAACTGGA
TATGGCCTTGGAATACTTGAAATTAAGCTTCCAAATGGTGTCTCGGTATGGGGACACAGGGGGGCCGTTCCAGGGTTTTC
CACTTTTGTTGGTGGAACACTTGGAGGTAAACATACACTCGCTATCAATTCGAACAGTTTAAACATTAATAATCCGGAAT
TTTTTAAAGATATTTTACTTGCTGAATTTAGCAAGTAG

Upstream 100 bases:

>100_bases
TGTTGCCTTTTCATCATTGGGAGAATGGATAGCTGTGTGGTTCGTATAGGACACTGCTATCAACTATCTATACAATTTTA
ATAGAAGAGAGGAATTCTTT

Downstream 100 bases:

>100_bases
GCAAAAAGGAAAAACGAAAAAATTTTGTCATTTGTAATTTCAATCGGAATAGATTATCGGTTGAAATGAGTATAGAGGGG
ATTAAGTATATAGAAACGAT

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKIRSKITCASLALLIAGSSLLYITPASIVKAEPTQNVSSSLQTSTQSNRTSVKKAIRDELQLGYPGILAQISKGGKTWS
YTAGVADLRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPDFAPGKAWSYSNTGYVLLGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
PGNSSVIPGTKHARGYLQLDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTG
YGLGILEIKLPNGVSVWGHRGAVPGFSTFVGGTLGGKHTLAINSNSLNINNPEFFKDILLAEFSK

Sequences:

>Translated_385_residues
MKIRSKITCASLALLIAGSSLLYITPASIVKAEPTQNVSSSLQTSTQSNRTSVKKAIRDELQLGYPGILAQISKGGKTWS
YTAGVADLRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPDFAPGKAWSYSNTGYVLLGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
PGNSSVIPGTKHARGYLQLDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTG
YGLGILEIKLPNGVSVWGHRGAVPGFSTFVGGTLGGKHTLAINSNSLNINNPEFFKDILLAEFSK
>Mature_385_residues
MKIRSKITCASLALLIAGSSLLYITPASIVKAEPTQNVSSSLQTSTQSNRTSVKKAIRDELQLGYPGILAQISKGGKTWS
YTAGVADLRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPDFAPGKAWSYSNTGYVLLGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
PGNSSVIPGTKHARGYLQLDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTG
YGLGILEIKLPNGVSVWGHRGAVPGFSTFVGGTLGGKHTLAINSNSLNINNPEFFKDILLAEFSK

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=274, Percent_Identity=25.5474452554745, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082101, Length=204, Percent_Identity=26.4705882352941, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17550934, Length=303, Percent_Identity=26.4026402640264, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533026, Length=339, Percent_Identity=26.8436578171091, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17565630, Length=243, Percent_Identity=27.5720164609054, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41799; Mature: 41799

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRSKITCASLALLIAGSSLLYITPASIVKAEPTQNVSSSLQTSTQSNRTSVKKAIRDE
CCCCHHHHHHHHHHHHHCCCEEEECCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQLGYPGILAQISKGGKTWSYTAGVADLRTKKPMKADFRFRIGSVTKTFIATVLLQLSGE
HHCCCCHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCC
NRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIADYINSKDFDITDIKKSYTAE
CCCCCCHHHHHHCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFVKMGISLPPDFAPGKAWSYSNTGYVLLGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
PGNSSVIPGTKHARGYLQLDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLL
CCCCCCCCCCCCCCCEEEECCCCHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHH
KEQQLKQMLTTVPTEREGTGYGLGILEIKLPNGVSVWGHRGAVPGFSTFVGGTLGGKHTL
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHCCCCCCCEEE
AINSNSLNINNPEFFKDILLAEFSK
EEECCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIRSKITCASLALLIAGSSLLYITPASIVKAEPTQNVSSSLQTSTQSNRTSVKKAIRDE
CCCCHHHHHHHHHHHHHCCCEEEECCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQLGYPGILAQISKGGKTWSYTAGVADLRTKKPMKADFRFRIGSVTKTFIATVLLQLSGE
HHCCCCHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCC
NRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIADYINSKDFDITDIKKSYTAE
CCCCCCHHHHHHCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFVKMGISLPPDFAPGKAWSYSNTGYVLLGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
PGNSSVIPGTKHARGYLQLDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLL
CCCCCCCCCCCCCCCEEEECCCCHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHH
KEQQLKQMLTTVPTEREGTGYGLGILEIKLPNGVSVWGHRGAVPGFSTFVGGTLGGKHTL
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHCCCCCCCEEE
AINSNSLNINNPEFFKDILLAEFSK
EEECCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]