Click here to switch to the map view.

The map label for this gene is yoeA [H]

Identifier: 52142380

GI number: 52142380

Start: 2985265

End: 2986674

Strand: Reverse

Name: yoeA [H]

Synonym: BCZK2862

Alternate gene names: 52142380

Gene position: 2986674-2985265 (Counterclockwise)

Preceding gene: 52142379

Following gene: 52142382

Centisome position: 56.34

GC content: 34.47

Gene sequence:

>1410_bases
GTGAAATCATCGATAGATAGTATTCAAAAAAGTAAAAAATTAAAAAATCAAGAAAAGGGAGAGAGAGCAACATGGAAATC
AATGTCTATGTTTCTAGTTCCCTTGCTTTTAAGTAACATATTACAATCAGTTGGACAATTATTTGGTATGGTGGTAGTTG
GACGATGGCTTGGTGTGAATGAATTAGCTGCCATTTCAGCATTTTTTCCATTATTCTTTTTACTTGTTTCATTTGTAATT
GGGATTGGATCGGGTAGTTCGATTTTAATTGGTCAGGCATTTGGAGCCCGTAATGAAGATCGTTTAAAAGCCATTGTTGG
TACGACATTAACATTTACCTTTATAATAGGCGTTATTTTGGCAATAGCGGGAAATGTATTTGCTTTGAAAATTATGCGTT
TTATGGGTACGCCAGAGAATATAATTGATATGAGTGTGCATTATGCGCGTATTTTATTTATTTCTATGCCAGTTTTATTT
CTATATTTCTCCTATACAACGTTTATACGAGGTACAGGAGATTCTAAGACACCGTTTTATTTCTTAATTGTTAGTACAGT
CTTAAATATAATTCTATTACCTATTCTAATTTTTGGTTGGCTAGGAATACCCAAACTTGGTGTGTACGGAGCTGCCTATG
CTTCTGTTATCTCGACCGTTGTAACATTTATTGTTATGCTTATGTATTTAAAGAAGAAGAATCATCCACTGCAATTAGAT
GAGACCGTACGGAAATATCTTCGTATGGATTGGAATTTATTAAAACTATTATTACGCCTTGGAATTCCAGCGAGTATTAA
TATGATTCTTGTTTCGTTATCTGAGATTGCGGTAATCGTATTTGTGAATCGTTTCGGTTCTGATGCGACTGCTGCATATG
GGGTTGTAAACCAGGTTGCAAGTTATGTTCAGATGCCTGCGGTTAGCCTTGGAATTACGGTATCTATTTTTGCTGCGCAA
TCTATTGGTGGGAAACAATTTAACCGATTACAGGAAGTTATTCGTGCTGGAATTATTATGAATTATATAATTGGTGGTAT
ATTAATTGCTTTTATTTACTTGTTTTCAAGAGAAATCTTATCGTTATTCTTAACGAACACGAATACAGTTGAAATTGCGC
ATAGTTTGGTGATGATTACACTTTGGAGTTACTTAATTTTCGGTCATGCTCAAATTATTGGTGCGACAATGCGAGCAAGT
GGAACTGTATTATGGCCCACTATTATCGGTGTCGTATCAATATGGCTTGTAGAAGTCCCTGTTGCTTATTACCTTTCTTA
TCATACAAATCTTGGTATAAAAGGAATATGGATTGGATATCCAGCAGCATATATTGCAAGTTTACTTTTGCAATATGGAT
ATTATAGAATTTCATGGAAGAAGAAACGAATTTCACGACTTGTTAGTTAG

Upstream 100 bases:

>100_bases
CAATGGATAAGATAATAACGTTAATTTAAAAATTTTTTTTATTCTTAACGTATTATTCTCGGAATAACATAATTCCTCCA
AATAAAAGGGGAAATCAAAT

Downstream 100 bases:

>100_bases
AATAGAAGGTGAAAAATGATATTCTCTTATAAGTTGTCAGTTTTAGGAGTATGACTATAACATCATCAAACGAATAAAAC
CGAGTTACCCTCAAACGGGA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MKSSIDSIQKSKKLKNQEKGERATWKSMSMFLVPLLLSNILQSVGQLFGMVVVGRWLGVNELAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGARNEDRLKAIVGTTLTFTFIIGVILAIAGNVFALKIMRFMGTPENIIDMSVHYARILFISMPVLF
LYFSYTTFIRGTGDSKTPFYFLIVSTVLNIILLPILIFGWLGIPKLGVYGAAYASVISTVVTFIVMLMYLKKKNHPLQLD
ETVRKYLRMDWNLLKLLLRLGIPASINMILVSLSEIAVIVFVNRFGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGGKQFNRLQEVIRAGIIMNYIIGGILIAFIYLFSREILSLFLTNTNTVEIAHSLVMITLWSYLIFGHAQIIGATMRAS
GTVLWPTIIGVVSIWLVEVPVAYYLSYHTNLGIKGIWIGYPAAYIASLLLQYGYYRISWKKKRISRLVS

Sequences:

>Translated_469_residues
MKSSIDSIQKSKKLKNQEKGERATWKSMSMFLVPLLLSNILQSVGQLFGMVVVGRWLGVNELAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGARNEDRLKAIVGTTLTFTFIIGVILAIAGNVFALKIMRFMGTPENIIDMSVHYARILFISMPVLF
LYFSYTTFIRGTGDSKTPFYFLIVSTVLNIILLPILIFGWLGIPKLGVYGAAYASVISTVVTFIVMLMYLKKKNHPLQLD
ETVRKYLRMDWNLLKLLLRLGIPASINMILVSLSEIAVIVFVNRFGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGGKQFNRLQEVIRAGIIMNYIIGGILIAFIYLFSREILSLFLTNTNTVEIAHSLVMITLWSYLIFGHAQIIGATMRAS
GTVLWPTIIGVVSIWLVEVPVAYYLSYHTNLGIKGIWIGYPAAYIASLLLQYGYYRISWKKKRISRLVS
>Mature_469_residues
MKSSIDSIQKSKKLKNQEKGERATWKSMSMFLVPLLLSNILQSVGQLFGMVVVGRWLGVNELAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGARNEDRLKAIVGTTLTFTFIIGVILAIAGNVFALKIMRFMGTPENIIDMSVHYARILFISMPVLF
LYFSYTTFIRGTGDSKTPFYFLIVSTVLNIILLPILIFGWLGIPKLGVYGAAYASVISTVVTFIVMLMYLKKKNHPLQLD
ETVRKYLRMDWNLLKLLLRLGIPASINMILVSLSEIAVIVFVNRFGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGGKQFNRLQEVIRAGIIMNYIIGGILIAFIYLFSREILSLFLTNTNTVEIAHSLVMITLWSYLIFGHAQIIGATMRAS
GTVLWPTIIGVVSIWLVEVPVAYYLSYHTNLGIKGIWIGYPAAYIASLLLQYGYYRISWKKKRISRLVS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=474, Percent_Identity=20.6751054852321, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1790477, Length=318, Percent_Identity=24.5283018867925, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321821, Length=377, Percent_Identity=20.9549071618037, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52094; Mature: 52094

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]