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The map label for this gene is ndhF [H]

Identifier: 52142368

GI number: 52142368

Start: 3003253

End: 3004785

Strand: Reverse

Name: ndhF [H]

Synonym: BCZK2874

Alternate gene names: 52142368

Gene position: 3004785-3003253 (Counterclockwise)

Preceding gene: 52142366

Following gene: 52142369

Centisome position: 56.68

GC content: 36.33

Gene sequence:

>1533_bases
ATGTTAATTTCGCTAAGTTCATCAACACTGTTAACATTATTTTTTATCGCGCTTAGTGCTTCTTGGCTAAGTGGATTATT
GTTTTTACATGCAAGGATGCCTTTACGTTTTGTTCATATCCATATTGGTATCGCTGCTTTGCCTTCATTGGTTTCTTTAC
TTGCACTTGTTAATCACAATGGAGATAGCGTTGTAGGGCCTTGGCATTTAGATACTTTAGCTTGGTTCATGGCTTTCTTC
GTTCTTACAATTGGTTTAATCATTCAGCGTTTCTCTGTACGTTACTTAATGGGAGATCGCTCATATCGAAAATACTTTGC
ACTTTTTACATTTACTACAGGTGTATCTTCGGTCGCATGGTTAAGCGATGATCTTCGTTTCATGATTATTTGTTGGGGAG
CAACTCTTATAGGGTTGGTTTTACTCATAGGTCTAAATAAAGGGTGGAAAGTAGTTAGTGAAGCAACAAAAATCTCAGGC
TATTTATTTACAATAAGTTGGATTGCCTTACTATTAGTTATCATTTGGCTATTCCAAATAACTGGACAGTGGCAGTTAAC
ATCAGTTTTAACGAATGAAAATGTAGCCCAATTTGGAACATTGGAGAAAACGGGAATTAACTTATTGATTATAGTAGCTG
TGATGATTCCAGCAGCACAATGGCCTTTTCAAAGATGGTTAATTGAATCAGCTGTTGCTCCAACTCCTGTTTCTGCTATT
ATGCATGCGGGTTTAGTAAATGCTGGCGGTATCATGTTAACTAGATTTTCGCCACTTTTTCATGATGATATTGCACAAAT
CATTTTACTAATTTTCTCTAGTATTTCGGTCTTAATAGGAACAGGAATTAGTTTAGTTCAAGTTGAGTATAAACGTCAGC
TAGTAGGTTCAACGATTGCACAAATGGGATTTATGCTGATTCAATGTGCATTAGGCGCTTATTTAGCAGCTGTTATTCAT
TTAATTTTACACGGTTTATTTAAAGCCACACTGTTTTTACAAGCTGGTTCTTCCGTACAACGTGTTGGGGTAGTGAAGCA
GTCTAATGAAAAGATATCTAATTTATGGATTATGGTCGGACGTGTTTTCGGATTATTTATAGCGATTGCTTTTTGGTTTA
CGACTTCTGGAGAAGGATATCAATTCGTTAGTGCGTTCATCTTAGGCTGGTCATTATACTTTTCATGGAAACAGCTTGTT
GTTTTTGGAGAGGGAAGAATGGGACGAATTGCTGGCTTAATAGTTTTGAGTGGATTTTCACTCATTTACTTTACTGTTCA
TAACTCTCTTTATAAATGGTTGCATACTGACATGTATCAGAATGCTCAACCGTCGGCTTCAGCCGTTATTTTTGTTATAA
GTCTCTTATTATTTGGTAGTGCTATTAGTACTCTTGTTACTCGTAATCAATCTTCTACAATATTTGCTGTAATGTATCTT
TGGTTCGTTCGAGTAGGTGAAGCAAGACAAAAGTCAGTAGAAAGTCATCCAAGCTATCTGAAACATGATGTATCAAAGGG
AGGTAATCAGTGA

Upstream 100 bases:

>100_bases
CGATGTACTAAAAAGAGTGAATAAAAATTGAAATTAAAAAAACTATCGTAATGAAAAGGAATTTTTATAGGTTATTTTCG
TTTGGAAGGGAGTATTTTAC

Downstream 100 bases:

>100_bases
TGAGCATACAGTCAATCGTAACGAAAGAAACTTTAAAAAAGAAAGATACAAACATTGAAATACAAGAAAAGAATATGAAT
GATTTAGTTGTATCTGCTAG

Product: NADH dehydrogenase subunit 5

Products: NA

Alternate protein names: NADH dehydrogenase subunit 5 [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHNGDSVVGPWHLDTLAWFMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAWLSDDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLLVIIWLFQITGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVEYKRQLVGSTIAQMGFMLIQCALGAYLAAVIH
LILHGLFKATLFLQAGSSVQRVGVVKQSNEKISNLWIMVGRVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYFSWKQLV
VFGEGRMGRIAGLIVLSGFSLIYFTVHNSLYKWLHTDMYQNAQPSASAVIFVISLLLFGSAISTLVTRNQSSTIFAVMYL
WFVRVGEARQKSVESHPSYLKHDVSKGGNQ

Sequences:

>Translated_510_residues
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHNGDSVVGPWHLDTLAWFMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAWLSDDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLLVIIWLFQITGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVEYKRQLVGSTIAQMGFMLIQCALGAYLAAVIH
LILHGLFKATLFLQAGSSVQRVGVVKQSNEKISNLWIMVGRVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYFSWKQLV
VFGEGRMGRIAGLIVLSGFSLIYFTVHNSLYKWLHTDMYQNAQPSASAVIFVISLLLFGSAISTLVTRNQSSTIFAVMYL
WFVRVGEARQKSVESHPSYLKHDVSKGGNQ
>Mature_510_residues
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHNGDSVVGPWHLDTLAWFMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAWLSDDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLLVIIWLFQITGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVEYKRQLVGSTIAQMGFMLIQCALGAYLAAVIH
LILHGLFKATLFLQAGSSVQRVGVVKQSNEKISNLWIMVGRVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYFSWKQLV
VFGEGRMGRIAGLIVLSGFSLIYFTVHNSLYKWLHTDMYQNAQPSASAVIFVISLLLFGSAISTLVTRNQSSTIFAVMYL
WFVRVGEARQKSVESHPSYLKHDVSKGGNQ

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=128, Percent_Identity=32.03125, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788614, Length=278, Percent_Identity=28.7769784172662, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788831, Length=131, Percent_Identity=32.0610687022901, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 56543; Mature: 56543

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
GDSVVGPWHLDTLAWFMAFFVLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
LSDDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKISGYLFTISWIALLLVIIWLFQI
HCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
CCCEEEEEECCCCCHHHHCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVEYKRQLVGSTIA
HHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QMGFMLIQCALGAYLAAVIHLILHGLFKATLFLQAGSSVQRVGVVKQSNEKISNLWIMVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHH
RVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYFSWKQLVVFGEGRMGRIAGLIVLSGFS
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
LIYFTVHNSLYKWLHTDMYQNAQPSASAVIFVISLLLFGSAISTLVTRNQSSTIFAVMYL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
WFVRVGEARQKSVESHPSYLKHDVSKGGNQ
HHHHHCHHHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
GDSVVGPWHLDTLAWFMAFFVLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
LSDDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKISGYLFTISWIALLLVIIWLFQI
HCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
CCCEEEEEECCCCCHHHHCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVEYKRQLVGSTIA
HHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QMGFMLIQCALGAYLAAVIHLILHGLFKATLFLQAGSSVQRVGVVKQSNEKISNLWIMVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHH
RVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYFSWKQLVVFGEGRMGRIAGLIVLSGFS
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
LIYFTVHNSLYKWLHTDMYQNAQPSASAVIFVISLLLFGSAISTLVTRNQSSTIFAVMYL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
WFVRVGEARQKSVESHPSYLKHDVSKGGNQ
HHHHHCHHHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]