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The map label for this gene is isdE [H]

Identifier: 52140959

GI number: 52140959

Start: 4398684

End: 4399559

Strand: Reverse

Name: isdE [H]

Synonym: BCZK4291

Alternate gene names: 52140959

Gene position: 4399559-4398684 (Counterclockwise)

Preceding gene: 52140958

Following gene: 52140960

Centisome position: 83.0

GC content: 35.16

Gene sequence:

>876_bases
GTGAAGAAAATTGCAAGTGTACTAATGGCTATCATTTTATTAGTAAGTATAGCTGGATGCTCGGCGCCCAAAAAAGAAGC
AGCAAAACAGGTGAAGAGTGAGAGTAAAGAGAGAGTTGTTGCTACGACAGTCGCTGTTACTGAAATTATGGATGCGTTAG
AAGTAGATTTAGTTGGTGTTCCAACGAGTACGAAAGATTTACCAAAGAGATATAAAGGGTTACCTGAAGTCGGGAATCCG
ATGAGTCCTGATATGGAAAAGGTAAAGTCATTAAAGCCGTCAGAAGTATTATCTGTTACAACACTTGAATATGAATTAAA
GCCAGTTTTTGATGGTGTAGGTATGAAAGCAAACTTTGTAGACTTAACTAGTTTAAAAAATATGCAAAATGCCATTAGTA
ATTTAGGTAAGCAATATGGGCGTGAGAAACAAGCTGAAGCAGTTGTAACGAAGTTAGATAAAAAGGTTGCTAGCATTCAA
AAAGAAGTAAAGGGAAAGAAAGAACCGACAGTACTTATTTTATTAGGTGTGCCGGGGAGTTATTTAGTAGCAACAGAGCA
TTCCTATATTGGTGATTTAGTGAAACAACTAGGTGGTAAAAATATTGTACAAGGTGAACAAGTAGAATATTTAGCTTCTA
ATACAGAGTATTTAAAGAAAGCTGATCCGGATATTATTTTACGAGCAGCTCATGGTATGCCTGATGAAGTTGTAAAAATG
TTTGATAAAGAATTTAAAACAAATGATATTTGGAAACACTTCGCTGCAGTTAAAAATAATCGTGTTTACGATTTAGAAGA
GCGTTTATTTGGAACGACAGGAAATTTAGCAGCAATTGAAGCGTTAGATGAATTGAAAAAAATGATGTATCCGTGA

Upstream 100 bases:

>100_bases
TAAATATAGAGCAGGTAGATTGTAATTTTTGGAGTCTTGATGCATGTTCGCGTGCATCAAGACTTGTTTCATATTGTTTG
GAAAGGAGTGGTGATTGAGA

Downstream 100 bases:

>100_bases
TGCATTTTCATATAAAGGAAGAGTGAAATGAATAAAAAAACTTGGAGTTTCCTCATTGTTACTGCATTACTTATCGTTAT
GACATCATTGTCAGCGATGA

Product: iron compound ABC transporter, iron compound-binding protein

Products: NA

Alternate protein names: Iron-regulated surface determinant protein E; Staphylococcal iron-regulated protein F [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLVGVPTSTKDLPKRYKGLPEVGNP
MSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKANFVDLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVASIQ
KEVKGKKEPTVLILLGVPGSYLVATEHSYIGDLVKQLGGKNIVQGEQVEYLASNTEYLKKADPDIILRAAHGMPDEVVKM
FDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP

Sequences:

>Translated_291_residues
MKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLVGVPTSTKDLPKRYKGLPEVGNP
MSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKANFVDLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVASIQ
KEVKGKKEPTVLILLGVPGSYLVATEHSYIGDLVKQLGGKNIVQGEQVEYLASNTEYLKKADPDIILRAAHGMPDEVVKM
FDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP
>Mature_291_residues
MKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLVGVPTSTKDLPKRYKGLPEVGNP
MSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKANFVDLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVASIQ
KEVKGKKEPTVLILLGVPGSYLVATEHSYIGDLVKQLGGKNIVQGEQVEYLASNTEYLKKADPDIILRAAHGMPDEVVKM
FDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP

Specific function: Involved in heme (porphyrin) scavenging. Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme. Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors t

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019957
- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 32015; Mature: 32015

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLVGV
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEC
PTSTKDLPKRYKGLPEVGNPMSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKANFV
CCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHEEEEEEEEEHHHHHCCCCCCCCHH
DLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVASIQKEVKGKKEPTVLILLGVPGS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
YLVATEHSYIGDLVKQLGGKNIVQGEQVEYLASNTEYLKKADPDIILRAAHGMPDEVVKM
EEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHCCCCCEEEECCCCCHHHHHH
FDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP
HHHHCCHHHHHHHHHHHHCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLVGV
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEC
PTSTKDLPKRYKGLPEVGNPMSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKANFV
CCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHEEEEEEEEEHHHHHCCCCCCCCHH
DLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVASIQKEVKGKKEPTVLILLGVPGS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
YLVATEHSYIGDLVKQLGGKNIVQGEQVEYLASNTEYLKKADPDIILRAAHGMPDEVVKM
EEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHCCCCCEEEECCCCCHHHHHH
FDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP
HHHHCCHHHHHHHHHHHHCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA