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The map label for this gene is fhuB [H]

Identifier: 52140960

GI number: 52140960

Start: 4397673

End: 4398656

Strand: Reverse

Name: fhuB [H]

Synonym: BCZK4290

Alternate gene names: 52140960

Gene position: 4398656-4397673 (Counterclockwise)

Preceding gene: 52140959

Following gene: 52140961

Centisome position: 82.98

GC content: 37.7

Gene sequence:

>984_bases
ATGAATAAAAAAACTTGGAGTTTCCTCATTGTTACTGCATTACTTATCGTTATGACATCATTGTCAGCGATGAAAGGGAG
TTTAGAAATAGGGATAGTAGACCTTGTACAAGGGATATTTACAGGGGCAAATGAAGATGTTGAGGTCATTAAAGATTTAC
GTTTTCCGCGTATTATTATTGCGTTATTCACTGGAGCAGCTCTTGCTGTTTCAGGTGTGCTTTTTCAAGCTGTTATGAAA
AACCCACTCGCTGATGCTGGGGTAATCGGGATATCTTCAGGAGCAAGTTTTATGACACTTGTTATTATAACGTTGTTCCC
GCAATTCTTTTTCTGGACACCAGTATTTGCCTTTTTAGGTGGTGCGTTTGCGTGTTATCTTGTTTATGCATTTTCATGGA
AGTCAGGGTTAAGTCCACTTCGTATTATTTTAGTTGGTATAGCTATTAATGCGATGTTTACTGGATTAAATGAATCGTTC
ATTACGATTTGTGGATATTTTATTAAGAGTATTAAGCAAACGACGACTTCTAATATAACGATGAAGACGTGGGGCGATGT
AGAAATAATGGTTACGTATGGAACAATTGGTTTGGTTCTTGCTCTGTTTGTAGGAGCTTGGTGTAACTTATTATCGTTAC
AAGATAAGACTGCAAAAAACTTAGGTTTGCACGTGACGAGAGTTCGTCTTATTATTTCTGCTATTGCAGTACTTTTAGCT
GCAGTATCAACAGCGATTGCAGGTGTTATTGCTTTTGTAGGATTACTCGTTCCGCACATTTCAAGGCAATTAGTCGGTTC
AGATCATAAAGTATTAATTCCATTTTCTGCTCTTGCAGGAGCGTTATTAATTTTGACGGCGGATACGATTGGAAGGTTAA
TTGTACCACCTAACGAAATTCCAGCGGCGACGATTATGGCAGTTATTGGTGGCCCATTCTTAATATTCTTGCTTAGAAAG
AGTGATAAAGTTCATGGAAATTAA

Upstream 100 bases:

>100_bases
TTTATTTGGAACGACAGGAAATTTAGCAGCAATTGAAGCGTTAGATGAATTGAAAAAAATGATGTATCCGTGATGCATTT
TCATATAAAGGAAGAGTGAA

Downstream 100 bases:

>100_bases
AAATGTAACCTTTTCGTATGATAATGTAACGGATCGATTAAAGTCGGTTAGTAGTGAAATAGAAATTGGTAAAGTGACAA
CAATTATTGGTCCAAATGGT

Product: iron compound ABC transporter, permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron-regulated surface determinant protein F; Staphylococcal iron-regulated protein G [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNKKTWSFLIVTALLIVMTSLSAMKGSLEIGIVDLVQGIFTGANEDVEVIKDLRFPRIIIALFTGAALAVSGVLFQAVMK
NPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLGGAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESF
ITICGYFIKSIKQTTTSNITMKTWGDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEIPAATIMAVIGGPFLIFLLRK
SDKVHGN

Sequences:

>Translated_327_residues
MNKKTWSFLIVTALLIVMTSLSAMKGSLEIGIVDLVQGIFTGANEDVEVIKDLRFPRIIIALFTGAALAVSGVLFQAVMK
NPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLGGAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESF
ITICGYFIKSIKQTTTSNITMKTWGDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEIPAATIMAVIGGPFLIFLLRK
SDKVHGN
>Mature_327_residues
MNKKTWSFLIVTALLIVMTSLSAMKGSLEIGIVDLVQGIFTGANEDVEVIKDLRFPRIIIALFTGAALAVSGVLFQAVMK
NPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLGGAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESF
ITICGYFIKSIKQTTTSNITMKTWGDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEIPAATIMAVIGGPFLIFLLRK
SDKVHGN

Specific function: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=282, Percent_Identity=32.6241134751773, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790741, Length=298, Percent_Identity=30.5369127516779, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786805, Length=287, Percent_Identity=35.191637630662, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786347, Length=282, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786804, Length=328, Percent_Identity=30.1829268292683, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788004, Length=282, Percent_Identity=32.6241134751773, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34906; Mature: 34906

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKTWSFLIVTALLIVMTSLSAMKGSLEIGIVDLVQGIFTGANEDVEVIKDLRFPRIII
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
ALFTGAALAVSGVLFQAVMKNPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESFITICGYFIKSIKQTTTSNIT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEE
MKTWGDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
EEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHH
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHEEHHHHCCEEECCCCC
PAATIMAVIGGPFLIFLLRKSDKVHGN
CHHHHHHHHCCHHHEEEECCCCCCCCC
>Mature Secondary Structure
MNKKTWSFLIVTALLIVMTSLSAMKGSLEIGIVDLVQGIFTGANEDVEVIKDLRFPRIII
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
ALFTGAALAVSGVLFQAVMKNPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESFITICGYFIKSIKQTTTSNIT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEE
MKTWGDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
EEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHH
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHEEHHHHCCEEECCCCC
PAATIMAVIGGPFLIFLLRKSDKVHGN
CHHHHHHHHCCHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA