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The map label for this gene is isdA [H]

Identifier: 52140958

GI number: 52140958

Start: 4399635

End: 4402445

Strand: Reverse

Name: isdA [H]

Synonym: BCZK4292

Alternate gene names: 52140958

Gene position: 4402445-4399635 (Counterclockwise)

Preceding gene: 52140957

Following gene: 52140959

Centisome position: 83.05

GC content: 34.12

Gene sequence:

>2811_bases
TTGAATAGATATTTTAAAATTGTTGTTGCGATGCTTTTAATGATATTTACATTCGTATCAACATTACAACCCCTTGCAGT
TCAAGCAGCGACTCAATTAGCTGACGGTGAATATTCAATCGGTTTTAAAGTTCTTAAAGATACATCGGATGAAGTATCTA
AGATGAATGACTATGTTGTAAGTCCAGCTACTTTAAAAGTAAAAGATGGCAAACAAAAAGTCGCATTTACTTTAAAGAAT
AGTGAATGGATTACACAGTTTACAACAGAAAAAGATGGTCAGTTTGTTGATGTAAATGTGATTGAAGAAAATAAAGAGAA
GAATACTAGAGTAGTAGAATTCGATGTAGCAGATGTAGCAAACATTTTAAATGGAAAAGTCAAAGTAGATATCGATGCGA
TGAATTATCATCATGTTTTTGATGTTCGCATTACATTTGATTCAAGCAGTATTACACCAGTTCATGTAGAAAAGCCAAAT
GAAAAAGAGGATCCAGCAAATAAGCCAGATCCAAATGAAACTACGGATCCAAGTCAGAAGCCCGACCAAAAGCCTGACTC
AGATCAACAACCAAATTCTAACACAATTGCAGATGGAGAGTACAGCATTCCATTTAAAGTGTTAAAAAACAAGACAGATG
AAGAATCTAGAATGAATGAAAATGTTATAAGTCCAGCGATATTAAAAGTAGAAAATGATAAGAAAAAAGTGCTTGTGACA
TTAAAAGGTAGCTCATTAATTAAAAATTTCCAAACGGAAAAAAATGGCGCATTTATTGATGCCAATGTAGTGAGTGAAGA
TAAAGAAAAAGATACAAGAGTAGTAGAATTTGAAGTAGACGATGTATCTAAAAAACTAAATACAAAAGTGTTTATTGAAA
TGGCATCAAGAAATTATAAACAAACGCATGAGGTACAGCTTTTATTTGACCAAGAAAAACTTGAGCCAATTAAGAATGAA
GAAAAACAACCGGATGAAGATAAAAAGCCGGAAGTAGAAAAACCAAATGCTGAAACAATTAAAGACGGTGAATACAGCAT
CAATTTCAAAGCTTTAAAAGATCAAACAGAAGAAATTTCAATGATGAACACGTATACAAAGAGTCCAGGCGTGTTAAAAG
TAAAAAACGGTAAAAAATATGTATCATTCACATTAACGAATAGTGCATGGATTACAAAGTTTGAATTTGAGAAAAATGGT
TCGTTCATTGATGCAAGTGTACTAAGTGAAGATAAAAAGGCTGATACACGCGTAGTGGAAGTAGAAGTAAACGACTTATC
TAAAAAGTTAAATGCAAAAGTCAAAGTAGATATCGATTCAATGAATTATCACCATTTCTACGACATTCAATTTGCATTTG
ATAAAGATAGCATGAAACCGTTAGACAACCAAGGCGGAAACGACAACCAAGGCGGAAACGACAACCAAGGCGGAAACGAC
AACCAAGGCGGAAACGACAACCAAGGCGGAAACGACAACCAAGGCGGAAACGAAAACCAAGGCGGAAACGAAAACCAAGG
CGGAAACGACAACCAAGGTGGAAACGAAAACCAAGGCGAGAACAATAACCAAGGTGGGAACGACAATCAAGGCGGAAACA
ATAACCAAGGTGGAAATAACAACCAAGATAATAACACAATCATTGATCCAAAAGCTCTTAAAGATGGTGAATACAGCATT
GGTTTTAAAGTTTTAAAAGATCAAACAGAAGAAATTTCAATCATGAACACATATACAAAGAATCCAGGTGTATTAAAAGT
AAAAGATGGTAAAAAGTATGTATCGTTTACATTAACGAATAGTGCGTGGATTACGAAGTTTGAGTATGAAAAAAATGGTT
CTTTCGTGGACGCGAAAGCGTTAAGCGAGAACAAAGAGAAAAACACAAAGGTAGTAGAAATAGAAGTAGATGATTTATCG
GAAAAATTAAATGCAAAAGTCAAAGTAGATATCGATGCAATGAATTATCACCATTTCTACGATGTTCAATTTGTATTTGA
TGAAGGTAGTATTAAAGCATTAGGTAACCGAGGCGGAAACGATAACCAAGGCGGAAACGACAACCAAGGCGGAAACGACA
ACCAAGGCGGAAACGACAACCAAGGCGGAAACGATAACCAAGGTGGAAACAATAACCAAGGTGGAAATAATAAACCAAAA
GTAATAGTTGATCCAAAAAATTTAGTGGATGGTCAATATGATATTCCATTTAAAGTGTTAAAAGATAAAACAAATGAACT
TTCAAAGATGCATGACTATACTGTACATCCAGCAAAATTAATTGTTAAAGATGGTAAAAAGTACATTGAGATGACCTTGA
AAAATAGTGCGTGGATTACGAAATTCCAAACAGAAAATAACAGCCTTTTTGCTGATGCGAAAGTAGTAAGCGAAGATAAA
AAGGCAAATACGAGAGTAGTGCAATTTGAAGTAAGTGATTTATTTGCGAAATTAAATGCAAAAGTGAAAGTAGATATTGA
TGAAATGAACTACCATCATTTCTACGATGTCCAAATTCAATTTGATACAAATAATATTGGTGCATTAGGAACGATTAAAG
AGGAGCCAAAAAAAGATCCAAAGAATGAATCGAAAAACCCAGTAACTACACCAAAAATAGATAATGTAAAAACAGTAGGA
ACTCCTGATTTTAACCGAAATGCAGATGGTAAAAAGAAAAACGAAGCTAATGATCCGAAAAAAGAAAAAAACTCAAAAAC
TGCAGATACAGCACAACTTGGTTTATACATGGTGTTACTGCTAGGTTCACTTGCTTTACTAGTTCGTAAATATAGAGCAG
GTAGATTGTAA

Upstream 100 bases:

>100_bases
GATGAAGCACGCATCGGATTATTTGCAACGTTACTCCTTATTTCGGGTGTTTTCTTAATTCGTAAAGTACGTCAAAACTA
AATAAAGGAGCGGTATTCCA

Downstream 100 bases:

>100_bases
TTTTTGGAGTCTTGATGCATGTTCGCGTGCATCAAGACTTGTTTCATATTGTTTGGAAAGGAGTGGTGATTGAGAGTGAA
GAAAATTGCAAGTGTACTAA

Product: cell surface protein

Products: NA

Alternate protein names: Fur-regulated protein A; Staphylococcal transferrin-binding protein A [H]

Number of amino acids: Translated: 936; Mature: 936

Protein sequence:

>936_residues
MNRYFKIVVAMLLMIFTFVSTLQPLAVQAATQLADGEYSIGFKVLKDTSDEVSKMNDYVVSPATLKVKDGKQKVAFTLKN
SEWITQFTTEKDGQFVDVNVIEENKEKNTRVVEFDVADVANILNGKVKVDIDAMNYHHVFDVRITFDSSSITPVHVEKPN
EKEDPANKPDPNETTDPSQKPDQKPDSDQQPNSNTIADGEYSIPFKVLKNKTDEESRMNENVISPAILKVENDKKKVLVT
LKGSSLIKNFQTEKNGAFIDANVVSEDKEKDTRVVEFEVDDVSKKLNTKVFIEMASRNYKQTHEVQLLFDQEKLEPIKNE
EKQPDEDKKPEVEKPNAETIKDGEYSINFKALKDQTEEISMMNTYTKSPGVLKVKNGKKYVSFTLTNSAWITKFEFEKNG
SFIDASVLSEDKKADTRVVEVEVNDLSKKLNAKVKVDIDSMNYHHFYDIQFAFDKDSMKPLDNQGGNDNQGGNDNQGGND
NQGGNDNQGGNDNQGGNENQGGNENQGGNDNQGGNENQGENNNQGGNDNQGGNNNQGGNNNQDNNTIIDPKALKDGEYSI
GFKVLKDQTEEISIMNTYTKNPGVLKVKDGKKYVSFTLTNSAWITKFEYEKNGSFVDAKALSENKEKNTKVVEIEVDDLS
EKLNAKVKVDIDAMNYHHFYDVQFVFDEGSIKALGNRGGNDNQGGNDNQGGNDNQGGNDNQGGNDNQGGNNNQGGNNKPK
VIVDPKNLVDGQYDIPFKVLKDKTNELSKMHDYTVHPAKLIVKDGKKYIEMTLKNSAWITKFQTENNSLFADAKVVSEDK
KANTRVVQFEVSDLFAKLNAKVKVDIDEMNYHHFYDVQIQFDTNNIGALGTIKEEPKKDPKNESKNPVTTPKIDNVKTVG
TPDFNRNADGKKKNEANDPKKEKNSKTADTAQLGLYMVLLLGSLALLVRKYRAGRL

Sequences:

>Translated_936_residues
MNRYFKIVVAMLLMIFTFVSTLQPLAVQAATQLADGEYSIGFKVLKDTSDEVSKMNDYVVSPATLKVKDGKQKVAFTLKN
SEWITQFTTEKDGQFVDVNVIEENKEKNTRVVEFDVADVANILNGKVKVDIDAMNYHHVFDVRITFDSSSITPVHVEKPN
EKEDPANKPDPNETTDPSQKPDQKPDSDQQPNSNTIADGEYSIPFKVLKNKTDEESRMNENVISPAILKVENDKKKVLVT
LKGSSLIKNFQTEKNGAFIDANVVSEDKEKDTRVVEFEVDDVSKKLNTKVFIEMASRNYKQTHEVQLLFDQEKLEPIKNE
EKQPDEDKKPEVEKPNAETIKDGEYSINFKALKDQTEEISMMNTYTKSPGVLKVKNGKKYVSFTLTNSAWITKFEFEKNG
SFIDASVLSEDKKADTRVVEVEVNDLSKKLNAKVKVDIDSMNYHHFYDIQFAFDKDSMKPLDNQGGNDNQGGNDNQGGND
NQGGNDNQGGNDNQGGNENQGGNENQGGNDNQGGNENQGENNNQGGNDNQGGNNNQGGNNNQDNNTIIDPKALKDGEYSI
GFKVLKDQTEEISIMNTYTKNPGVLKVKDGKKYVSFTLTNSAWITKFEYEKNGSFVDAKALSENKEKNTKVVEIEVDDLS
EKLNAKVKVDIDAMNYHHFYDVQFVFDEGSIKALGNRGGNDNQGGNDNQGGNDNQGGNDNQGGNDNQGGNNNQGGNNKPK
VIVDPKNLVDGQYDIPFKVLKDKTNELSKMHDYTVHPAKLIVKDGKKYIEMTLKNSAWITKFQTENNSLFADAKVVSEDK
KANTRVVQFEVSDLFAKLNAKVKVDIDEMNYHHFYDVQIQFDTNNIGALGTIKEEPKKDPKNESKNPVTTPKIDNVKTVG
TPDFNRNADGKKKNEANDPKKEKNSKTADTAQLGLYMVLLLGSLALLVRKYRAGRL
>Mature_936_residues
MNRYFKIVVAMLLMIFTFVSTLQPLAVQAATQLADGEYSIGFKVLKDTSDEVSKMNDYVVSPATLKVKDGKQKVAFTLKN
SEWITQFTTEKDGQFVDVNVIEENKEKNTRVVEFDVADVANILNGKVKVDIDAMNYHHVFDVRITFDSSSITPVHVEKPN
EKEDPANKPDPNETTDPSQKPDQKPDSDQQPNSNTIADGEYSIPFKVLKNKTDEESRMNENVISPAILKVENDKKKVLVT
LKGSSLIKNFQTEKNGAFIDANVVSEDKEKDTRVVEFEVDDVSKKLNTKVFIEMASRNYKQTHEVQLLFDQEKLEPIKNE
EKQPDEDKKPEVEKPNAETIKDGEYSINFKALKDQTEEISMMNTYTKSPGVLKVKNGKKYVSFTLTNSAWITKFEFEKNG
SFIDASVLSEDKKADTRVVEVEVNDLSKKLNAKVKVDIDSMNYHHFYDIQFAFDKDSMKPLDNQGGNDNQGGNDNQGGND
NQGGNDNQGGNDNQGGNENQGGNENQGGNDNQGGNENQGENNNQGGNDNQGGNNNQGGNNNQDNNTIIDPKALKDGEYSI
GFKVLKDQTEEISIMNTYTKNPGVLKVKDGKKYVSFTLTNSAWITKFEYEKNGSFVDAKALSENKEKNTKVVEIEVDDLS
EKLNAKVKVDIDAMNYHHFYDVQFVFDEGSIKALGNRGGNDNQGGNDNQGGNDNQGGNDNQGGNDNQGGNNNQGGNNKPK
VIVDPKNLVDGQYDIPFKVLKDKTNELSKMHDYTVHPAKLIVKDGKKYIEMTLKNSAWITKFQTENNSLFADAKVVSEDK
KANTRVVQFEVSDLFAKLNAKVKVDIDEMNYHHFYDVQIQFDTNNIGALGTIKEEPKKDPKNESKNPVTTPKIDNVKTVG
TPDFNRNADGKKKNEANDPKKEKNSKTADTAQLGLYMVLLLGSLALLVRKYRAGRL

Specific function: Transfers its hemin to hemin-free isdC (apo-isdC) directly probably through the activated holo-isdA-apo-isdC complex and driven by the higher affinity of apo-isdC for the cofactor. The reaction is reversible. Binds transferrin, lactoferrin, heme, hemoglob

COG id: COG5386

COG function: function code M; Cell surface protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 NEAT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR006635
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00746 Gram_pos_anchor; PF05031 NEAT [H]

EC number: NA

Molecular weight: Translated: 104540; Mature: 104540

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50978 NEAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYFKIVVAMLLMIFTFVSTLQPLAVQAATQLADGEYSIGFKVLKDTSDEVSKMNDYVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCEEE
SPATLKVKDGKQKVAFTLKNSEWITQFTTEKDGQFVDVNVIEENKEKNTRVVEFDVADVA
CCEEEEEECCCEEEEEEEECCCEEEEEECCCCCCEEEEEEEECCCCCCCEEEEEEHHHHH
NILNGKVKVDIDAMNYHHVFDVRITFDSSSITPVHVEKPNEKEDPANKPDPNETTDPSQK
HHHCCEEEEEEEECCEEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCC
PDQKPDSDQQPNSNTIADGEYSIPFKVLKNKTDEESRMNENVISPAILKVENDKKKVLVT
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHCCCCCCEEEEEECCCEEEEEE
LKGSSLIKNFQTEKNGAFIDANVVSEDKEKDTRVVEFEVDDVSKKLNTKVFIEMASRNYK
ECCCHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHHHCCCEEEEEECCCCCC
QTHEVQLLFDQEKLEPIKNEEKQPDEDKKPEVEKPNAETIKDGEYSINFKALKDQTEEIS
CCEEEEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHH
MMNTYTKSPGVLKVKNGKKYVSFTLTNSAWITKFEFEKNGSFIDASVLSEDKKADTRVVE
HHHHCCCCCCEEEECCCCEEEEEEEECCEEEEEEEECCCCCEEEHHHHCCCCCCCCEEEE
VEVNDLSKKLNAKVKVDIDSMNYHHFYDIQFAFDKDSMKPLDNQGGNDNQGGNDNQGGND
EEHHHHHHHCCCEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
NQGGNDNQGGNDNQGGNENQGGNENQGGNDNQGGNENQGENNNQGGNDNQGGNNNQGGNN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NQDNNTIIDPKALKDGEYSIGFKVLKDQTEEISIMNTYTKNPGVLKVKDGKKYVSFTLTN
CCCCCEEECCHHCCCCCCEECEEEECCCCCEEEEEEEECCCCCEEEEECCCEEEEEEEEC
SAWITKFEYEKNGSFVDAKALSENKEKNTKVVEIEVDDLSEKLNAKVKVDIDAMNYHHFY
CEEEEEEEECCCCCEEEHHHHHCCCCCCCEEEEEEHHHHHHHCCCEEEEEEEEECCEEEE
DVQFVFDEGSIKALGNRGGNDNQGGNDNQGGNDNQGGNDNQGGNDNQGGNNNQGGNNKPK
EEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
VIVDPKNLVDGQYDIPFKVLKDKTNELSKMHDYTVHPAKLIVKDGKKYIEMTLKNSAWIT
EEECCHHHCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCEEEE
KFQTENNSLFADAKVVSEDKKANTRVVQFEVSDLFAKLNAKVKVDIDEMNYHHFYDVQIQ
EEEECCCCEEEEEEECCCCCCCCCEEEEEEHHHHHHHCCCEEEEEEECCCCEEEEEEEEE
FDTNNIGALGTIKEEPKKDPKNESKNPVTTPKIDNVKTVGTPDFNRNADGKKKNEANDPK
ECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCH
KEKNSKTADTAQLGLYMVLLLGSLALLVRKYRAGRL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNRYFKIVVAMLLMIFTFVSTLQPLAVQAATQLADGEYSIGFKVLKDTSDEVSKMNDYVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCEEE
SPATLKVKDGKQKVAFTLKNSEWITQFTTEKDGQFVDVNVIEENKEKNTRVVEFDVADVA
CCEEEEEECCCEEEEEEEECCCEEEEEECCCCCCEEEEEEEECCCCCCCEEEEEEHHHHH
NILNGKVKVDIDAMNYHHVFDVRITFDSSSITPVHVEKPNEKEDPANKPDPNETTDPSQK
HHHCCEEEEEEEECCEEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCC
PDQKPDSDQQPNSNTIADGEYSIPFKVLKNKTDEESRMNENVISPAILKVENDKKKVLVT
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHCCCCCCEEEEEECCCEEEEEE
LKGSSLIKNFQTEKNGAFIDANVVSEDKEKDTRVVEFEVDDVSKKLNTKVFIEMASRNYK
ECCCHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHHHCCCEEEEEECCCCCC
QTHEVQLLFDQEKLEPIKNEEKQPDEDKKPEVEKPNAETIKDGEYSINFKALKDQTEEIS
CCEEEEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHH
MMNTYTKSPGVLKVKNGKKYVSFTLTNSAWITKFEFEKNGSFIDASVLSEDKKADTRVVE
HHHHCCCCCCEEEECCCCEEEEEEEECCEEEEEEEECCCCCEEEHHHHCCCCCCCCEEEE
VEVNDLSKKLNAKVKVDIDSMNYHHFYDIQFAFDKDSMKPLDNQGGNDNQGGNDNQGGND
EEHHHHHHHCCCEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
NQGGNDNQGGNDNQGGNENQGGNENQGGNDNQGGNENQGENNNQGGNDNQGGNNNQGGNN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NQDNNTIIDPKALKDGEYSIGFKVLKDQTEEISIMNTYTKNPGVLKVKDGKKYVSFTLTN
CCCCCEEECCHHCCCCCCEECEEEECCCCCEEEEEEEECCCCCEEEEECCCEEEEEEEEC
SAWITKFEYEKNGSFVDAKALSENKEKNTKVVEIEVDDLSEKLNAKVKVDIDAMNYHHFY
CEEEEEEEECCCCCEEEHHHHHCCCCCCCEEEEEEHHHHHHHCCCEEEEEEEEECCEEEE
DVQFVFDEGSIKALGNRGGNDNQGGNDNQGGNDNQGGNDNQGGNDNQGGNNNQGGNNKPK
EEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
VIVDPKNLVDGQYDIPFKVLKDKTNELSKMHDYTVHPAKLIVKDGKKYIEMTLKNSAWIT
EEECCHHHCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCEEEE
KFQTENNSLFADAKVVSEDKKANTRVVQFEVSDLFAKLNAKVKVDIDEMNYHHFYDVQIQ
EEEECCCCEEEEEEECCCCCCCCCEEEEEEHHHHHHHCCCEEEEEEECCCCEEEEEEEEE
FDTNNIGALGTIKEEPKKDPKNESKNPVTTPKIDNVKTVGTPDFNRNADGKKKNEANDPK
ECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCH
KEKNSKTADTAQLGLYMVLLLGSLALLVRKYRAGRL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA