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The map label for this gene is isdC [H]

Identifier: 52140957

GI number: 52140957

Start: 4402465

End: 4403169

Strand: Reverse

Name: isdC [H]

Synonym: BCZK4293

Alternate gene names: 52140957

Gene position: 4403169-4402465 (Counterclockwise)

Preceding gene: 52140955

Following gene: 52140958

Centisome position: 83.06

GC content: 33.62

Gene sequence:

>705_bases
ATGAGAAAGATTTCTGTATTACCCGCTTTTATTATAACGCTCGTATGTATGCTAGCTTTTCTTGTCATGCCATATGGAAA
AGTTTCAGCACAACTAGCTGACGGTACGTATGATATTAACTATGTCATTCAAAAAGCGGAAAATGATTCAGCTTCAATGG
CAAATGATTATTTTGAAAAACCAGCTAAGCTAGTTGTGAAAAATGGTGAGATGAGAGTACAAATTCCGATGAATCATAGT
GCTTGGATTACAGAATTTAAAGCACCTGAGAACGGGAATTTTGTTGATGCAAAAGTTGTTAGTAAAGATGAATCAGCAGA
TAAAAGAACTGTAGAGTTTAAAATAGATGATTTATCTAAACCAGCAGCTGCAAAAATTCATGTTGTTGTACCAAACGTAA
ATTATGACCATAACTACACCATTCGCTTTGCATTTGATGCAAATGTAAAAGTGATAGGTGGAGAAAATAAAGCAACTGAT
GTAACAAAGAATAGTGATCAAACAAAAACAGATACAAAAGTAGAAGAAGTGAAAAAAGAAGAGAGTAAAGAAGTAAATAA
AGAGACGAACAAAGGAACAAATGAAAGTGCTAAAACTGAAAAAACCGATAATCCAAAAACTGGTGATGAAGCACGCATCG
GATTATTTGCAACGTTACTCCTTATTTCGGGTGTTTTCTTAATTCGTAAAGTACGTCAAAACTAA

Upstream 100 bases:

>100_bases
AATAATGATAGAAGATTATTATTTTTTTCTAACATATTGAGAATAATTATCATTTTCAAAAAAGTAGGGATGAAAGATAA
ACAAGGAGGAAGTAAGCCAA

Downstream 100 bases:

>100_bases
ATAAAGGAGCGGTATTCCATTGAATAGATATTTTAAAATTGTTGTTGCGATGCTTTTAATGATATTTACATTCGTATCAA
CATTACAACCCCTTGCAGTT

Product: cell surface protein, iron transport associated

Products: NA

Alternate protein names: Staphylococcal iron-regulated protein D [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRKISVLPAFIITLVCMLAFLVMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEKPAKLVVKNGEMRVQIPMNHS
AWITEFKAPENGNFVDAKVVSKDESADKRTVEFKIDDLSKPAAAKIHVVVPNVNYDHNYTIRFAFDANVKVIGGENKATD
VTKNSDQTKTDTKVEEVKKEESKEVNKETNKGTNESAKTEKTDNPKTGDEARIGLFATLLLISGVFLIRKVRQN

Sequences:

>Translated_234_residues
MRKISVLPAFIITLVCMLAFLVMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEKPAKLVVKNGEMRVQIPMNHS
AWITEFKAPENGNFVDAKVVSKDESADKRTVEFKIDDLSKPAAAKIHVVVPNVNYDHNYTIRFAFDANVKVIGGENKATD
VTKNSDQTKTDTKVEEVKKEESKEVNKETNKGTNESAKTEKTDNPKTGDEARIGLFATLLLISGVFLIRKVRQN
>Mature_234_residues
MRKISVLPAFIITLVCMLAFLVMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEKPAKLVVKNGEMRVQIPMNHS
AWITEFKAPENGNFVDAKVVSKDESADKRTVEFKIDDLSKPAAAKIHVVVPNVNYDHNYTIRFAFDANVKVIGGENKATD
VTKNSDQTKTDTKVEEVKKEESKEVNKETNKGTNESAKTEKTDNPKTGDEARIGLFATLLLISGVFLIRKVRQN

Specific function: Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e., mediates the transfer of the iron-containing nutrient from isdABH

COG id: COG5386

COG function: function code M; Cell surface protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 NEAT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019909
- InterPro:   IPR006635
- InterPro:   IPR017505 [H]

Pfam domain/function: PF05031 NEAT [H]

EC number: NA

Molecular weight: Translated: 26066; Mature: 26066

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS50978 NEAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKISVLPAFIITLVCMLAFLVMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEEECCCCCHHHHHHHHHC
PAKLVVKNGEMRVQIPMNHSAWITEFKAPENGNFVDAKVVSKDESADKRTVEFKIDDLSK
CCEEEEECCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCC
PAAAKIHVVVPNVNYDHNYTIRFAFDANVKVIGGENKATDVTKNSDQTKTDTKVEEVKKE
CCCEEEEEEECCCCCCCCEEEEEEEECCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
ESKEVNKETNKGTNESAKTEKTDNPKTGDEARIGLFATLLLISGVFLIRKVRQN
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKISVLPAFIITLVCMLAFLVMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEEECCCCCHHHHHHHHHC
PAKLVVKNGEMRVQIPMNHSAWITEFKAPENGNFVDAKVVSKDESADKRTVEFKIDDLSK
CCEEEEECCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCC
PAAAKIHVVVPNVNYDHNYTIRFAFDANVKVIGGENKATDVTKNSDQTKTDTKVEEVKKE
CCCEEEEEEECCCCCCCCEEEEEEEECCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
ESKEVNKETNKGTNESAKTEKTDNPKTGDEARIGLFATLLLISGVFLIRKVRQN
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA